DK2125865T3 - Opløsning af proteasekrystaller i fermenteringssuppe - Google Patents

Opløsning af proteasekrystaller i fermenteringssuppe

Info

Publication number
DK2125865T3
DK2125865T3 DK08717479.3T DK08717479T DK2125865T3 DK 2125865 T3 DK2125865 T3 DK 2125865T3 DK 08717479 T DK08717479 T DK 08717479T DK 2125865 T3 DK2125865 T3 DK 2125865T3
Authority
DK
Denmark
Prior art keywords
protease crystals
dissolving
fermentation soup
soup
fermentation
Prior art date
Application number
DK08717479.3T
Other languages
English (en)
Inventor
Sune Jakobsen
Kim Uhre Hansen
Svend Kaasgaard
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37991373&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2125865(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of DK2125865T3 publication Critical patent/DK2125865T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK08717479.3T 2007-03-15 2008-03-06 Opløsning af proteasekrystaller i fermenteringssuppe DK2125865T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07104220 2007-03-15
PCT/EP2008/052732 WO2008110498A1 (en) 2007-03-15 2008-03-06 Solubilization of protease crystals in fermentation broth

Publications (1)

Publication Number Publication Date
DK2125865T3 true DK2125865T3 (da) 2014-10-06

Family

ID=37991373

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08717479.3T DK2125865T3 (da) 2007-03-15 2008-03-06 Opløsning af proteasekrystaller i fermenteringssuppe

Country Status (6)

Country Link
US (1) US8828677B2 (da)
EP (1) EP2125865B1 (da)
JP (1) JP5453116B2 (da)
CN (1) CN101631797B (da)
DK (1) DK2125865T3 (da)
WO (1) WO2008110498A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009152176A2 (en) 2008-06-09 2009-12-17 Danisco Us Inc., Genencor Division Recovery of insoluble enzyme from fermentation broth and formulation of insoluble enzyme
EP2451937A1 (en) * 2009-07-09 2012-05-16 Novozymes A/S Flocculation with divalent salt and phosphate
EP2552934B1 (en) 2010-03-30 2015-07-15 Novozymes A/S Crystal metabolite recovery
JP6591998B2 (ja) * 2014-03-28 2019-10-16 ノボザイムス アクティーゼルスカブ 低ｐＨでのタンパク質結晶の再可溶化
CN108367245A (zh) * 2015-12-09 2018-08-03 巴斯夫欧洲公司 在解吸条件下从发酵固体纯化蛋白质的方法
US20200109388A1 (en) 2017-04-03 2020-04-09 Novozymes A/S Recovery Process
US20210380667A1 (en) 2018-10-10 2021-12-09 Novozymes A/S Chymotrypsin Inhibitor Variants And The Use Thereof
US20220186177A1 (en) 2019-02-20 2022-06-16 Basf Se Industrial fermentation process for bacillus using defined medium and magnesium feed
MX2021010109A (es) 2019-02-20 2021-09-21 Basf Se Proceso de fermentacion industrial para bacillus mediante el uso de un medio definido y una alimentacion de oligoelementos.
MX2021015364A (es) 2019-06-13 2022-01-24 Basf Se Metodo de recuperacion de una proteina de un caldo de fermentacion mediante el uso de un cation divalente.
US20220340865A1 (en) 2019-07-02 2022-10-27 Basf Se Method for preparing a fermentation medium
PL3959326T3 (pl) 2019-07-05 2023-10-09 Basf Se Przemysłowy sposób fermentacji dla komórek bakteryjnych z wykorzystaniem kultury wstępnej okresowej z zasilaniem
MX2023009756A (es) 2021-02-22 2023-09-04 Basf Se Variantes de amilasa.
EP4047088A1 (en) 2021-02-22 2022-08-24 Basf Se Amylase variants
EP4565711A1 (en) 2022-08-02 2025-06-11 Basf Se Stabilized protein production process using bacillus host cells with salt feed
EP4569099A1 (en) 2022-08-11 2025-06-18 Basf Se Enzyme compositions comprising protease, mannanase, and/or cellulase
EP4569096A2 (en) 2022-08-11 2025-06-18 Basf Se Enzyme compositions comprising an amylase
US20260055347A1 (en) 2022-08-11 2026-02-26 Basf Se Amylase variants
WO2024033135A2 (en) 2022-08-11 2024-02-15 Basf Se Amylase variants
EP4612285A1 (en) 2022-11-04 2025-09-10 Basf Se Polypeptides having protease activity for use in detergent compositions
EP4612286A1 (en) 2022-11-04 2025-09-10 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2024094735A1 (en) 2022-11-04 2024-05-10 Basf Se Polypeptides having protease activity for use in detergent compositions
EP4389864A1 (en) 2022-12-20 2024-06-26 Basf Se Cutinases
CN121666450A (zh) 2023-08-08 2026-03-13 巴斯夫欧洲公司 具有失活的金属蛋白酶的改良的芽孢杆菌细胞
EP4624572A1 (en) 2024-03-27 2025-10-01 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202379A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202369A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202374A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202370A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202372A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340926A (en) * 1983-03-25 1994-08-23 Celltech, Limited Process for the recovery of recombinantly produced protein from insoluble aggregate
WO1991009943A1 (en) 1989-12-21 1991-07-11 Novo Nordisk A/S Method for crystallization of enzymes
JPH0466086A (ja) * 1990-07-04 1992-03-02 Tosoh Corp ウロキナーゼ前駆体含有溶液の取得方法
EP0574050A1 (en) * 1992-05-19 1993-12-15 Gist-Brocades N.V. Large scale separation and purification of fermentation product
DK83093D0 (da) 1993-07-09 1993-07-09 Novo Nordisk As Fremgangsmaade
BE1009844A3 (fr) * 1995-12-22 1997-10-07 Genencor Int Procede de recolte d'une proteine.
EP1149160B1 (en) * 1999-01-25 2006-04-19 Novozymes A/S Recovery of a protein at high ph
EP1289629B1 (en) 2000-05-18 2004-08-04 Novozymes A/S Microfiltration using activated carbon

Also Published As

Publication number Publication date
CN101631797A (zh) 2010-01-20
US8828677B2 (en) 2014-09-09
EP2125865B1 (en) 2014-07-30
JP2010521146A (ja) 2010-06-24
EP2125865A1 (en) 2009-12-02
US20080227175A1 (en) 2008-09-18
WO2008110498A1 (en) 2008-09-18
CN101631797B (zh) 2015-12-16
JP5453116B2 (ja) 2014-03-26

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