DK2155222T3 - Ekstrakt af Trigonella foenum-graecum - Google Patents
Ekstrakt af Trigonella foenum-graecum Download PDFInfo
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- DK2155222T3 DK2155222T3 DK08715639.4T DK08715639T DK2155222T3 DK 2155222 T3 DK2155222 T3 DK 2155222T3 DK 08715639 T DK08715639 T DK 08715639T DK 2155222 T3 DK2155222 T3 DK 2155222T3
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Plant Substances (AREA)
- Extraction Or Liquid Replacement (AREA)
Claims (13)
1. Fremgangsmåde til opnåelse af et ekstrakt, hvilken fremgangsmåde omfatter trinnene, der går ud på a. at fremstille en blanding af frø opnået af Trigonella foenum-graecum og vand, b. at inkubere blandingen i mindst 3 timer ved en temperatur på mellem 10 og 45°C, c. at koge blandingen i 10 til 45 minutter for at frigøre kimene fra frøene, og d. at indvinde et flydende ekstrakt fra blandingen.
2. Fremgangsmåde ifølge krav 1, som omfatter det yderligere trin, der går ud på at fryse den inkuberede blanding forud for varmebehandlingen ifølge trin c eller at fryse den varmebehandlede blanding.
3. Fremgangsmåde ifølge krav 2, hvor det yderligere trin omfatter at fryse blandingen som defineret i krav 2 og at gentage trin c.
4. Fremgangsmåde til opnåelse af en ekstraktfraktion ved at udføre revers fasekromatografi af ekstraktet, der er opnået ifølge et hvilket som helst af kravene 1 til 3, på Lichroprep RP-18 (40-63 pm) af størrelse B (Merck) under anvendelse af følgende gradient: 0-1 min FhO/AcN 98:2, og derefter under anvendelse af en konstant gradient fra 1-40 min op til 100 % AcN og indsamling af fraktionen i tidsrummet mellem 5 og 10 min.
5. Fremgangsmåde til opnåelse af et ekstrakt eller en fraktion deraf ifølge et hvilket som helst af kravene 1 til 4, hvor ekstraktet eller fraktionen deraf opkoncentreres ved helt eller delvis at fjerne opløsningsmiddel ved en metode, der er valgt fra gruppen bestående af membranfiltrering, afdampning, udfældning, ekstraktion, azeotrop destillation, lyofilisering, spraytørring og kombinationer deraf.
6. Farmaceutisk sammensætning, der omfatter et ekstrakt eller en fraktion deraf, som er opnået ved en fremgangsmåde ifølge et hvilket som helst af kravene 1 til 5, til anvendelse ved behandling af en betændelses- eller infektionstilstand.
7. Farmaceutisk sammensætning ifølge krav 6, hvor betændelsestilstanden er valgt fra gruppen bestående af bledermatitis, akne, astma og en betændelsestilstand i mave-tarmkanalen.
8. Farmaceutisk sammensætning ifølge krav 6, hvor infektionstilstanden er herpes simplex.
9. Farmaceutisk sammensætning ifølge krav 6, hvor infektionstilstanden er valgt fra gruppen bestående af et betændt sår, et kirurgisk sår, impetigo, en stafylokok, såsom infektion med staphylococcus aureus, en infektion i mundhulen, periodontal sygdom, en infektion i øjet eller øjets hjælpeorganer, almindelig forkølelse, forkølelsessår, vorter og pharyngitis.
10. Farmaceutisk sammensætning ifølge krav 9, hvor den periodontale sygdom er valgt blandt gingivitis, periodontitis og halitosis.
11. Farmaceutisk sammensætning ifølge et hvilket som helst af kravene 6 til 10, hvor den farmaceutiske sammensætning er formuleret som en mundskyllevæske, tyggegummi, tandpasta, balsam, plaster, læbesalve, spray, salve, gel, kapsel, drop eller tablet.
12. Anvendelse af ekstraktet, der er opnået ved en fremgangsmåde ifølge et hvilket som helst af kravene 1 til 5, til fremstilling af en sammensætning til desinficering af hud; anlæg såsom køkkener, slagterier, toiletter og stalde; køkkenudstyr såsom køleskabe eller frysere; vand; vandbeholdere; boliger med lugt af syge personer, eller betonelementer.
13. Anvendelse af ekstraktet, der er opnået ved en fremgangsmåde ifølge et hvilket som helst af kravene 1 til 5, til fremstilling af en sammensætning til konservering af fødevarer såsom kød, fjerkræ og produkter deraf.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91165307P | 2007-04-13 | 2007-04-13 | |
| PCT/DK2008/050086 WO2008125120A2 (en) | 2007-04-13 | 2008-04-14 | Extract of trigonella foenum-graecum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2155222T3 true DK2155222T3 (da) | 2018-01-22 |
Family
ID=39739903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08715639.4T DK2155222T3 (da) | 2007-04-13 | 2008-04-14 | Ekstrakt af Trigonella foenum-graecum |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US9107920B2 (da) |
| EP (1) | EP2155222B1 (da) |
| JP (1) | JP2010527326A (da) |
| KR (1) | KR20090129490A (da) |
| CN (1) | CN101687002B (da) |
| AU (1) | AU2008238445B2 (da) |
| BR (1) | BRPI0810532A2 (da) |
| CA (1) | CA2682138A1 (da) |
| DK (1) | DK2155222T3 (da) |
| EA (1) | EA018425B1 (da) |
| ES (1) | ES2655876T3 (da) |
| IL (1) | IL201047A (da) |
| LT (1) | LT2155222T (da) |
| NO (1) | NO2155222T3 (da) |
| PL (1) | PL2155222T3 (da) |
| WO (1) | WO2008125120A2 (da) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022214671A1 (en) | 2021-04-08 | 2022-10-13 | Qur Medical Aps | Pharmaceutical composition for prevention or treatment of virus-induced disease |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8513203B2 (en) * | 2011-05-02 | 2013-08-20 | Indus Biotech Private Limited | Composition and method thereof |
| CN102532248B (zh) * | 2011-12-19 | 2013-09-04 | 四川省中医药科学院 | 制备胡芦巴皂苷b的方法 |
| WO2013171764A2 (en) * | 2012-04-30 | 2013-11-21 | Rubicon Research Private Limited | Ophthalmic formulations |
| WO2014075676A1 (en) * | 2012-11-15 | 2014-05-22 | V-Biotek Holding Aps | Amines from trigonella foemum - graecum |
| MX2017014198A (es) * | 2015-05-06 | 2018-06-28 | Procter & Gamble | Desintoxicacion de los factores de virulencia microbiana en la cavidad oral. |
| ITUB20152286A1 (it) * | 2015-07-17 | 2017-01-17 | Harven S A S | Composizione anti herpes |
| EP3436041B1 (en) | 2016-03-31 | 2023-05-24 | Gojo Industries, Inc. | Sanitizer composition with probiotic/prebiotic active ingredient |
| US10806769B2 (en) | 2016-03-31 | 2020-10-20 | Gojo Industries, Inc. | Antimicrobial peptide stimulating cleansing composition |
| EP3435765A1 (en) | 2016-03-31 | 2019-02-06 | Gojo Industries, Inc. | Antimicrobial peptide stimulating sanitizing composition |
| EP3463393A1 (en) | 2016-06-03 | 2019-04-10 | Jens Steen Olsen | A composition comprising a mixture of an extract and bentonite |
| DE102016007774A1 (de) * | 2016-06-24 | 2017-12-28 | Hossam El Dakroury | Antibiotikum - goldene Flüssigkeit - |
| DK178915B1 (en) * | 2016-07-29 | 2017-05-22 | Helge Vinther Christensen | Composition and method for preventing algal growth on outdoor surfaces |
| JP2020500860A (ja) | 2016-11-23 | 2020-01-16 | ゴジョ・インダストリーズ・インコーポレイテッド | プロバイオティック/プレバイオティックな有効成分を含む消毒薬組成物 |
| CN106667785A (zh) * | 2017-02-27 | 2017-05-17 | 宁波圆明工业设计有限公司 | 一种利用PericoannosinA作为抗菌组分的牙膏 |
| US20200030226A1 (en) * | 2018-07-27 | 2020-01-30 | Johnson & Johnson Consumer Inc. | Botanical and bacterial extracts displaying retinol-like activity |
| WO2020021477A2 (en) | 2018-07-27 | 2020-01-30 | Johnson & Johnson Vision Care, Inc. | Compositions and methods for treating the eye |
| US10966948B2 (en) | 2019-07-23 | 2021-04-06 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| US11969454B2 (en) | 2019-11-19 | 2024-04-30 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| US20230405068A1 (en) | 2020-11-06 | 2023-12-21 | Handelsselskabet Af 20.10.2020 Aps | Radiation-induced fibrosis treatment |
| TR2021015672A2 (tr) * | 2021-10-07 | 2023-04-24 | Elbasheer Omer | Zona, yara ve ci̇lt enfeksi̇yonlarinin engellenmesi̇ne ve mi̇gren, artri̇t hastaliğinin tedavi̇si̇ne yöneli̇k bi̇tki̇sel bi̇leşenler i̇çeri̇kli̇ bi̇r krem |
| JP7705427B2 (ja) * | 2022-05-19 | 2025-07-09 | ルミスター バイオテクノロジー,インク. | コロナウイルス感染抑制のための植物成分組成物及び生薬組成物 |
| CN115336596A (zh) * | 2022-09-01 | 2022-11-15 | 武汉安慧生物科技有限公司 | 杀线虫剂及其制备方法和应用 |
| WO2025083459A1 (en) * | 2023-10-21 | 2025-04-24 | Carlos Alvarado | A multifunctional vulnerary composition |
Family Cites Families (5)
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| GB1239555A (da) * | 1967-08-30 | 1971-07-21 | ||
| AU6141498A (en) * | 1997-02-04 | 1998-08-25 | John V. Kosbab | Compositions and methods for prevention and treatment of vascular degenerative diseases |
| CN1313435C (zh) * | 2003-10-27 | 2007-05-02 | 成都华高药业有限公司 | 一种从葫芦巴中提取4-羟基异亮氨酸制品的新方法 |
| US8337915B2 (en) * | 2004-01-10 | 2012-12-25 | S George Aburdeineh | Fenugreek seed extract to lower blood cholesterol |
| US7645466B2 (en) * | 2004-03-02 | 2010-01-12 | Tsi Group Limited | Methods for deriving, isolating, and/or extracting amino acid compositions from Fenugreek seed |
-
2008
- 2008-04-14 NO NO08715639A patent/NO2155222T3/no unknown
- 2008-04-14 ES ES08715639.4T patent/ES2655876T3/es active Active
- 2008-04-14 JP JP2010502420A patent/JP2010527326A/ja active Pending
- 2008-04-14 US US12/595,715 patent/US9107920B2/en active Active
- 2008-04-14 EA EA200970942A patent/EA018425B1/ru not_active IP Right Cessation
- 2008-04-14 BR BRPI0810532-4A2A patent/BRPI0810532A2/pt not_active Application Discontinuation
- 2008-04-14 DK DK08715639.4T patent/DK2155222T3/da active
- 2008-04-14 PL PL08715639T patent/PL2155222T3/pl unknown
- 2008-04-14 KR KR1020097022218A patent/KR20090129490A/ko not_active Withdrawn
- 2008-04-14 LT LTEP08715639.4T patent/LT2155222T/lt unknown
- 2008-04-14 EP EP08715639.4A patent/EP2155222B1/en active Active
- 2008-04-14 CN CN200880011813.3A patent/CN101687002B/zh active Active
- 2008-04-14 AU AU2008238445A patent/AU2008238445B2/en not_active Ceased
- 2008-04-14 WO PCT/DK2008/050086 patent/WO2008125120A2/en not_active Ceased
- 2008-04-14 CA CA002682138A patent/CA2682138A1/en not_active Abandoned
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2009
- 2009-09-17 IL IL201047A patent/IL201047A/en active IP Right Grant
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2015
- 2015-07-07 US US14/793,153 patent/US10195239B2/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022214671A1 (en) | 2021-04-08 | 2022-10-13 | Qur Medical Aps | Pharmaceutical composition for prevention or treatment of virus-induced disease |
Also Published As
| Publication number | Publication date |
|---|---|
| LT2155222T (lt) | 2018-02-12 |
| EA018425B1 (ru) | 2013-07-30 |
| CN101687002A (zh) | 2010-03-31 |
| CA2682138A1 (en) | 2008-10-23 |
| JP2010527326A (ja) | 2010-08-12 |
| US9107920B2 (en) | 2015-08-18 |
| PL2155222T3 (pl) | 2018-06-29 |
| ES2655876T3 (es) | 2018-02-22 |
| US10195239B2 (en) | 2019-02-05 |
| EP2155222A2 (en) | 2010-02-24 |
| KR20090129490A (ko) | 2009-12-16 |
| EA200970942A1 (ru) | 2010-04-30 |
| US20160000845A1 (en) | 2016-01-07 |
| AU2008238445A1 (en) | 2008-10-23 |
| BRPI0810532A2 (pt) | 2014-10-21 |
| EP2155222B1 (en) | 2017-11-15 |
| WO2008125120A3 (en) | 2009-05-28 |
| IL201047A (en) | 2016-09-29 |
| IL201047A0 (en) | 2010-05-17 |
| AU2008238445B2 (en) | 2012-02-02 |
| NO2155222T3 (da) | 2018-04-14 |
| WO2008125120A2 (en) | 2008-10-23 |
| CN101687002B (zh) | 2014-03-26 |
| US20100129296A1 (en) | 2010-05-27 |
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