DK2155867T3 - Stabile enzymatiske systemer til generering af persyre - Google Patents
Stabile enzymatiske systemer til generering af persyre Download PDFInfo
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- DK2155867T3 DK2155867T3 DK08747632.1T DK08747632T DK2155867T3 DK 2155867 T3 DK2155867 T3 DK 2155867T3 DK 08747632 T DK08747632 T DK 08747632T DK 2155867 T3 DK2155867 T3 DK 2155867T3
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- water
- oxidase
- enzyme
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000012064 sodium phosphate buffer Substances 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000007655 standard test method Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 108010038851 tannase Proteins 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- MSLRPWGRFCKNIZ-UHFFFAOYSA-J tetrasodium;hydrogen peroxide;dicarbonate Chemical compound [Na+].[Na+].[Na+].[Na+].OO.OO.OO.[O-]C([O-])=O.[O-]C([O-])=O MSLRPWGRFCKNIZ-UHFFFAOYSA-J 0.000 description 1
- 229960004072 thrombin Drugs 0.000 description 1
- 108010030159 thrombin receptor peptide 14 Proteins 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000006276 transfer reaction Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 229940005605 valeric acid Drugs 0.000 description 1
- 230000003253 viricidal effect Effects 0.000 description 1
- 210000002845 virion Anatomy 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000001790 virustatic effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38636—Preparations containing enzymes, e.g. protease or amylase containing enzymes other than protease, amylase, lipase, cellulase, oxidase or reductase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
- C11D17/04—Detergent materials or soaps characterised by their shape or physical properties combined with or containing other objects
- C11D17/041—Compositions releasably affixed on a substrate or incorporated into a dispensing means
- C11D17/042—Water soluble or water disintegrable containers or substrates containing cleaning compositions or additives for cleaning compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38654—Preparations containing enzymes, e.g. protease or amylase containing oxidase or reductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/54—Acetic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Enzymes And Modification Thereof (AREA)
Claims (36)
- STABILE ENZYMATISKE SYSTEMER TIL GENERERING AF PERSYRE PATENTKRAV1. Alt-i-en-sammensætning omfattende et perhydrolaseenzym, en hydrogenperoxidkilde og et estersubstrat, hvor sammensætningen genererer en persyre, når den blandes med vand, og hvor esteren omfatter mindre end 5 vægt-% vand, og hvor estersubstratet er en væske og perhydrolaseenzymet og hydrogenperoxidkilden er tørre faststoffer suspenderet i væsken, og hvor estersubstratet er udvalgt fra gruppen bestående af: methylacetat, ethylacetat, propylacetat, triacetin (l,3-diacetyloxypropan-2-yl-acetat) og propylenglycoldiacetat.
- 2. Sammensætning ifølge krav 1, hvor esteren omfatter mindre end 1, mindre end 0,5 eller mindre end 0,1 vægt-% vand.
- 3. Sammensætning ifølge krav 1, hvor persyren er udvalgt fra pereddikesyre, pemonansyre, perpropionsyre, perbutansyre, perpentansyre og perhexansyre.
- 4. Sammensætning ifølge krav 3, hvor persyren er pereddikesyre.
- 5. Sammensætning ifølge krav 1, hvor estersubstratet er propylenglycoldiacetat.
- 6. Sammensætning ifølge krav 1, hvor perhydrolaseenzymet omfatter amino syre sekvens ifølge SEQ ID NO: 1.
- 7. Sammensætning ifølge krav 1, hvor perhydrolaseenzymet er S54V-varianten af SEQ ID NO: 1.
- 8. Sammensætning ifølge krav 1, hvor hydrogenperoxidkilden er en hydrogenperoxidgenerende forbindelse udvalgt fra natriumpercarbonat, natriumperborat og ureahydrogenperoxid.
- 9. Sammensætning ifølge krav 8, hvor hydrogenperoxidkilden er natriumpercarbonat.
- 10. Sammensætning ifølge krav 1, hvor sammensætningen omfatter 0,001 til 1 vægt-% perhydrolaseenzym, 35 til 45 vægt-% natriumpercarbonat og 55 til 65 vægt-% propylenglycoldiacetat.
- 11. Sammensætning ifølge krav 1, hvor hydrogenperoxidkilden er et enzymatisk system til generering af hydrogenperoxid omfattende en oxidase og substrat heraf.
- 12. Sammensætning ifølge krav 11, hvor oxidasen er udvalgt fra glucoseoxidase, sorbitoloxidase, hexoseoxidase, cholinoxidase, alkoholoxidase, glyceroloxidase, cholesteroloxidase, pyranoseoxidase, carboxyalkoholoxidase, L-aminosyreoxidase, glycinoxidase, pyruvatoxidase, glutamatoxidase, sarcosinoxidase, lysinoxidase, lactatoxidase, vanillyloxidase, glycolatoxidase, galactoseoxidase, uricase, oxalatoxidase og xanthinoxidase.
- 13. Sammensætning ifølge krav 1, hvilken sammensætning endvidere omfatter mindst ét supplerende enzym, der er udvalgt fra proteaser, cellulaser, amylaser og mikrocellevægsnedbrydende enzymer.
- 14. Sammensætning ifølge krav 1, hvor sammensætningen endvidere omfatter mindst ét overfladeaktivt middel.
- 15. Sammensætning ifølge krav 1, hvor sammensætningen bevarer persyregenererende aktivitet i mindst 7 dage efter at have været opbevaret ved en omgivelsestemperatur fra 18 °C til 25 °C.
- 16. Fremgangsmåde til fremstilling af en dekontamineringsopløsning, hvilken fremgangsmåde omfatter tilsætning af sammensætningen ifølge et hvilket som helst af kravene 1 til 15 til vand, hvor sammensætningen forinden har været opbevaret ved omgivelsestemperatur i mindst 7 dage, og blanding i mindst 20 minutter.
- 17. Fremgangsmåde til dekontaminering, hvilken fremgangsmåde omfatter: (a) tilvejebringelse af en sammensætning ifølge et hvilket som helst af kravene 1 til 15, hvor sammensætningen forinden har været opbevaret ved omgivelsestemperatur i mindst 7 dage; (b) tilsætning af sammensætningen til vand og blanding, hvorved der genereres en vandig persyreopløsning; (c) eksponering af et emne omfattende en kontaminant for opløsningen.
- 18. Fremgangsmåde ifølge krav 17, hvor sammensætningen er indeholdt i en vandopløselig beholder.
- 19. Fremgangsmåde ifølge krav 18, hvor beholderen er en pose fremstillet af polyvinylalkoholfilm.
- 20. Fremgangsmåde ifølge krav 17, hvor vandet er steriliseret.
- 21. Fremgangsmåde ifølge krav 17, hvor eksponeringen omfatter eksponering af emnet for opløsningen ved høj temperatur.
- 22. Fremgangsmåde ifølge krav 17, hvor kontaminanten omfatter et toksin udvalgt fra botulinumtoksin, anthraxtoksin, ricin, scombrotoksin, ciguatoksin, tetrodotoksin, mycotoksiner og en hvilken som helst kombination deraf.
- 23. Fremgangsmåde ifølge krav 17, hvor kontaminanten omfatter et patogen, der er udvalgt fra bakterier, vira, svampe, parasitter, prioner og en hvilken som helst kombination deraf.
- 24. Fremgangsmåde ifølge krav 23, hvor patogenet er udvalgt blandt Bacillus spp., B. anthracis, Clostridium spp., C. botulinum, C. perfringens, Listeria spp., Staphylococcus spp., Streptococcus spp., Salmonella spp., Shigella, ssp., E. coli, Yersinia spp., Y. pestis, Francisella spp., F. tularensis, Camplyobacter ssp., Vibrio spp., Brucella spp., Cryptosporidium spp., Giardia spp., Cyclospora spp. og Trichinella spp.
- 25. Fremgangsmåde ifølge krav 17, hvor emnet er udvalgt blandt hårde overflader, stof, fødevarer, foder, udstyr, tæpper, gulvtæpper, tekstiler, medicinske instrumenter og veterinære instrumenter.
- 26. Fremgangsmåde ifølge krav 17, hvor omgivelsestemperaturen er fra 18 °C til 25 °C.
- 27. System omfattende en vandopløselig beholder omfattende en stabil sammensætning ifølge et hvilket som helst af kravene 1 til 15.
- 28. System ifølge krav 27, hvor beholderen er en pose, ampul, kapsel eller kugle.
- 29. System ifølge krav 27, hvor den vandopløselige beholder er fremstillet af et vandopløseligt polymermateriale, polyvinylalkohol, polyethylenoxider, celluloseafledte vandopløselige carbohydrater og polylactider.
- 30. Fremgangsmåde til fremstilling af en dekontamineringsopløsning omfattende tilsætning af systemet ifølge krav 27 til vand og blanding.
- 31. Kit til dekontaminering omfattende den stabile sammensætning ifølge et hvilket som helst af kravene 1 til 15 ved emballering.
- 32. Kit ifølge krav 31, hvor sammensætningen er i en vandopløselig beholder.
- 33. Kit ifølge krav 32, hvor den vandopløselige beholder er en pose, ampul, kapsel eller kugle.
- 34. Kit ifølge krav 32, hvor den vandopløselige beholder er fremstillet af et vandopløseligt polymermateriale, der er udvalgt fra polyvinylalkohol, polyethylenoxider, celluloseafledte vandopløselige carbohydrater og polylactider.
- 35. Kit ifølge krav 31, hvilket kit endvidere omfatter en tom blandebeholder til blanding af sammensætningen med vand.
- 36. Kit ifølge krav 31, hvilket kit endvidere omfatter vand i en forseglet beholder, hvor vandet er steriliseret.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91725207P | 2007-05-10 | 2007-05-10 | |
| PCT/US2008/062633 WO2008140988A1 (en) | 2007-05-10 | 2008-05-05 | Stable enzymatic peracid generating systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2155867T3 true DK2155867T3 (da) | 2016-01-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08747632.1T DK2155867T3 (da) | 2007-05-10 | 2008-05-05 | Stabile enzymatiske systemer til generering af persyre |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100189707A1 (da) |
| EP (1) | EP2155867B1 (da) |
| JP (1) | JP5408126B2 (da) |
| CN (1) | CN101821385A (da) |
| AU (1) | AU2008251642B2 (da) |
| DK (1) | DK2155867T3 (da) |
| IL (1) | IL201160A (da) |
| NZ (1) | NZ579789A (da) |
| SG (1) | SG183703A1 (da) |
| WO (1) | WO2008140988A1 (da) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0719181D0 (en) * | 2007-10-02 | 2007-11-14 | Reckitt Benckiser Nv | Stain treating composition |
| CA2709480C (en) * | 2007-12-20 | 2016-06-21 | Danisco Us Inc. | Enzymatic prevention and control of biofilm |
| DE102008024084A1 (de) * | 2008-05-17 | 2009-11-19 | Clariant International Ltd. | Wasch- und Reinigungsmittel |
| US20120021486A1 (en) * | 2009-01-16 | 2012-01-26 | Cerasela Zoica Dinu | Enzyme-based nanoscale decontaminating composites |
| EP2403809B1 (en) * | 2009-03-03 | 2015-06-24 | Danisco US Inc. | Method of oxidative decolorization of dyes with enzymatically generated peracid |
| JP5730306B2 (ja) * | 2009-07-27 | 2015-06-10 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ | 過酸ベースの除去可能な抗菌性コーティング組成物の酵素的その場調製および使用方法 |
| CN102782209A (zh) * | 2009-08-27 | 2012-11-14 | 丹尼斯科美国公司 | 组合的纺织品磨蚀和颜色修饰 |
| WO2011090980A1 (en) | 2010-01-20 | 2011-07-28 | Danisco Us Inc. | Mold treatment |
| EP2377914B1 (en) | 2010-04-19 | 2016-11-09 | The Procter & Gamble Company | Mildly alkaline, low-built, solid fabric treatment detergent composition comprising perhydrolase |
| CN102844491B (zh) | 2010-03-26 | 2016-03-09 | 丹尼斯科美国公司 | 使用具有过水解酶活性的酶处理角质纤维 |
| EP2655646A4 (en) * | 2010-12-20 | 2014-05-21 | Du Pont | TARGETED PERHYDROLASES |
| RU2013133845A (ru) * | 2010-12-20 | 2015-01-27 | Е.И.Дюпон Де Немур Энд Компани | Ферментативное образование перкислоты для применения в продуктах для ухода за волосами |
| WO2012084426A1 (en) | 2010-12-22 | 2012-06-28 | Unilever Nv | Enzymatic laundry detergent composition for the promotion of hygiene and the prevention of malodour |
| EP2842423B1 (en) | 2011-03-24 | 2018-07-18 | Enviro Tech Chemical Services Inc. | Method for the generation of peracetic acid on site at the point-of-use. |
| US8546449B2 (en) | 2011-03-24 | 2013-10-01 | Enviro Tech Chemical Services, Inc. | Methods and compositions for the generation of peracetic acid on site at the point-of-use |
| PH12014500416A1 (en) * | 2011-09-14 | 2014-04-14 | Colgate Palmolive Co | Tooth whitening strip |
| WO2013096321A2 (en) | 2011-12-19 | 2013-06-27 | Colgate-Palmolive Company | Peracid-generating compositions |
| MX354223B (es) | 2011-12-19 | 2018-02-19 | Colgate Palmolive Co | Sistema que provee una reaccion catalizada por perhidrolasas. |
| US20130284637A1 (en) * | 2012-04-30 | 2013-10-31 | Danisco Us Inc. | Unit-dose format perhydrolase systems |
| US8871699B2 (en) | 2012-09-13 | 2014-10-28 | Ecolab Usa Inc. | Detergent composition comprising phosphinosuccinic acid adducts and methods of use |
| US20140308162A1 (en) | 2013-04-15 | 2014-10-16 | Ecolab Usa Inc. | Peroxycarboxylic acid based sanitizing rinse additives for use in ware washing |
| US9994799B2 (en) | 2012-09-13 | 2018-06-12 | Ecolab Usa Inc. | Hard surface cleaning compositions comprising phosphinosuccinic acid adducts and methods of use |
| US9752105B2 (en) | 2012-09-13 | 2017-09-05 | Ecolab Usa Inc. | Two step method of cleaning, sanitizing, and rinsing a surface |
| NZ726323A (en) | 2014-04-30 | 2020-02-28 | Matoke Holdings Ltd | Antimicrobial compositions |
| EP3766523A1 (en) | 2014-12-18 | 2021-01-20 | Ecolab USA Inc. | Generation of peroxyformic acid through polyhydric alcohol formate |
| US9944894B2 (en) | 2015-01-16 | 2018-04-17 | General Electric Company | Pluripotent stem cell expansion and passage using a rocking platform bioreactor |
| CN106544296B (zh) * | 2016-10-20 | 2019-07-16 | 清华大学深圳研究生院 | 促进冈比亚藻生长、光合作用及分泌雪卡毒素的微生物、方法及试剂盒 |
| JPWO2019059162A1 (ja) * | 2017-09-21 | 2020-10-22 | エンビロテックジャパン株式会社 | 鳥卵表面の殺菌方法 |
| WO2019077336A1 (en) * | 2017-10-16 | 2019-04-25 | Matoke Holdings Limited | DOUBLE DISTRIBUTOR CONTAINING WATER AND ANTIMICROBIAL COMPOSITION |
| GB201716986D0 (en) | 2017-10-16 | 2017-11-29 | Matoke Holdings Ltd | Antimicrobial compositions |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| WO2019241635A1 (en) | 2018-06-15 | 2019-12-19 | Ecolab Usa Inc. | On site generated performic acid compositions for teat treatment |
| US11421191B1 (en) | 2018-11-15 | 2022-08-23 | Ecolab Usa Inc. | Acidic cleaner |
| CN110577973B (zh) * | 2019-09-23 | 2022-06-14 | 山东大学 | 一种体外催化ω-氨基酸生产二元羧酸的方法 |
| US12252667B2 (en) | 2020-04-07 | 2025-03-18 | Church & Dwight Co., Inc. | Laundry detergent composition |
| CN117412678A (zh) | 2021-04-14 | 2024-01-16 | 普瑞纳动物营养有限公司 | 使用产生过氧化氢的组合物缓和隐孢子虫病 |
| CN115806952B (zh) * | 2022-09-14 | 2024-05-03 | 福建师范大学 | 可与葡萄糖氧化酶高效偶联的耻垢分枝杆菌酰基转移酶突变体及其制备方法和应用 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE739340A (da) * | 1968-10-01 | 1970-03-02 | ||
| GB1590432A (en) * | 1976-07-07 | 1981-06-03 | Novo Industri As | Process for the production of an enzyme granulate and the enzyme granuate thus produced |
| US4689297A (en) * | 1985-03-05 | 1987-08-25 | Miles Laboratories, Inc. | Dust free particulate enzyme formulation |
| US5350563A (en) * | 1986-02-06 | 1994-09-27 | Steris Corporation | Cold sterilant with extended active life |
| US5030240A (en) * | 1986-06-09 | 1991-07-09 | The Clorox Company | Enzymatic peracid bleaching system |
| US5814501A (en) * | 1990-06-04 | 1998-09-29 | Genencor International, Inc. | Process for making dust-free enzyme-containing particles from an enzyme-containing fermentation broth |
| JP2814142B2 (ja) * | 1990-10-11 | 1998-10-22 | ライオン株式会社 | ポリビニルアルコールフィルム入り漂白洗浄剤 |
| US5879920A (en) * | 1991-10-07 | 1999-03-09 | Genencor International, Inc. | Coated enzyme-containing granule |
| US5324649A (en) * | 1991-10-07 | 1994-06-28 | Genencor International, Inc. | Enzyme-containing granules coated with hydrolyzed polyvinyl alcohol or copolymer thereof |
| US5783541A (en) * | 1994-09-12 | 1998-07-21 | Procter & Gamble Company | Unit packaged detergent |
| US5576282A (en) * | 1995-09-11 | 1996-11-19 | The Procter & Gamble Company | Color-safe bleach boosters, compositions and laundry methods employing same |
| MA24137A1 (fr) * | 1996-04-16 | 1997-12-31 | Procter & Gamble | Fabrication d'agents de surface ramifies . |
| US6248706B1 (en) * | 1996-05-13 | 2001-06-19 | Genencor International, Inc. | Enzyme granulate for washing and cleaning |
| AU738231B2 (en) * | 1997-01-10 | 2001-09-13 | Hinton, Elizabeth Jane | Detergent |
| US6112380A (en) * | 1997-02-07 | 2000-09-05 | Lulirama International, Inc. | Novelty lace having expandable aglets |
| WO1998039405A1 (en) * | 1997-03-07 | 1998-09-11 | The Procter & Gamble Company | Bleach compositions containing metal bleach catalyst, and bleach activators and/or organic percarboxylic acids |
| US6037319A (en) * | 1997-04-01 | 2000-03-14 | Dickler Chemical Laboratories, Inc. | Water-soluble packets containing liquid cleaning concentrates |
| DE19718977A1 (de) * | 1997-05-05 | 1998-11-12 | Henkel Kgaa | Bleichendes Textilwaschverfahren |
| US6171551B1 (en) * | 1998-02-06 | 2001-01-09 | Steris Corporation | Electrolytic synthesis of peracetic acid and other oxidants |
| DE19812589A1 (de) * | 1998-03-23 | 1999-10-07 | Degussa | Perameisensäure enthaltendes wäßriges Desinfektionsmittel, Verfahren zu dessen Herstellung und deren Verwendung |
| ES2237209T3 (es) * | 1998-10-27 | 2005-07-16 | Genencor International, Inc. | Granulo de matriz. |
| DE60026970T2 (de) * | 1999-01-08 | 2006-11-30 | Genencor International, Inc., Palo Alto | Zusammensetzungen mit niedriger dichte und partikeln der diese enthalten |
| US6492312B1 (en) * | 2001-03-16 | 2002-12-10 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Water soluble sachet with a dishwashing enhancing particle |
| FI111459B (fi) * | 2001-04-04 | 2003-07-31 | Kemira Chemicals Oy | Menetelmä stabiilin peretikkahappotuotteen valmistamiseksi |
| DE60201142T2 (de) * | 2001-04-20 | 2005-10-20 | Kuraray Co., Ltd., Kurashiki | Wasserlösliche Folie und Verpackung, welche dieselbe verwendet |
| US6683037B2 (en) * | 2002-04-19 | 2004-01-27 | Colgate-Palmolive Company | Cleaning system including a liquid cleaning composition disposed in a water soluble container |
| WO2003099987A1 (en) * | 2002-05-23 | 2003-12-04 | Unilever N.V. | Article and process for cleaning fabrics |
| JP4056859B2 (ja) * | 2002-11-11 | 2008-03-05 | 日本合成化学工業株式会社 | 水溶性フィルム |
| DE10260903A1 (de) * | 2002-12-20 | 2004-07-08 | Henkel Kgaa | Neue Perhydrolasen |
| US7022656B2 (en) * | 2003-03-19 | 2006-04-04 | Monosol, Llc. | Water-soluble copolymer film packet |
| US7754460B2 (en) * | 2003-12-03 | 2010-07-13 | Danisco Us Inc. | Enzyme for the production of long chain peracid |
| CN103333870A (zh) * | 2003-12-03 | 2013-10-02 | 丹尼斯科美国公司 | 过水解酶 |
| EP1877566B1 (en) * | 2005-04-29 | 2009-02-18 | E.I. Du Pont De Nemours And Company | Enzymatic production of peracids using perhydrolytic enzymes |
| US7550420B2 (en) * | 2005-04-29 | 2009-06-23 | E. I. Dupont De Nemours And Company | Enzymatic production of peracids using perhydrolytic enzymes |
| EP1879994A1 (en) * | 2005-05-13 | 2008-01-23 | The Procter and Gamble Company | Bleaching product |
| US20070082832A1 (en) * | 2005-10-06 | 2007-04-12 | Dicosimo Robert | Enzymatic production of peracids from carboxylic acid ester substrates using non-heme haloperoxidases |
| US7563758B2 (en) * | 2005-10-06 | 2009-07-21 | E. I. Du Pont De Nemours And Company | Enzymatic production of peracids using Lactobacilli having perhydrolysis activity |
| WO2007133263A2 (en) * | 2005-12-09 | 2007-11-22 | Genencor International, Inc. | Acyl transferase useful for decontamination |
| GB0614278D0 (en) * | 2006-07-19 | 2006-08-30 | Insense Ltd | Hydrogen peroxide delivery system |
-
2008
- 2008-05-05 DK DK08747632.1T patent/DK2155867T3/da active
- 2008-05-05 EP EP08747632.1A patent/EP2155867B1/en active Active
- 2008-05-05 NZ NZ579789A patent/NZ579789A/en unknown
- 2008-05-05 CN CN200880015489A patent/CN101821385A/zh active Pending
- 2008-05-05 WO PCT/US2008/062633 patent/WO2008140988A1/en not_active Ceased
- 2008-05-05 JP JP2010507582A patent/JP5408126B2/ja active Active
- 2008-05-05 AU AU2008251642A patent/AU2008251642B2/en active Active
- 2008-05-05 US US12/593,386 patent/US20100189707A1/en not_active Abandoned
- 2008-05-05 SG SG2012058715A patent/SG183703A1/en unknown
-
2009
- 2009-09-24 IL IL201160A patent/IL201160A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US20100189707A1 (en) | 2010-07-29 |
| SG183703A1 (en) | 2012-09-27 |
| NZ579789A (en) | 2012-05-25 |
| EP2155867A1 (en) | 2010-02-24 |
| IL201160A (en) | 2013-10-31 |
| JP5408126B2 (ja) | 2014-02-05 |
| EP2155867B1 (en) | 2015-10-14 |
| AU2008251642B2 (en) | 2014-02-13 |
| JP2010526909A (ja) | 2010-08-05 |
| IL201160A0 (en) | 2011-08-01 |
| CN101821385A (zh) | 2010-09-01 |
| AU2008251642A1 (en) | 2008-11-20 |
| WO2008140988A1 (en) | 2008-11-20 |
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