DK2175877T3 - Anvendelse af muterede antitrombiner til behandling eller forebyggelse af koagulationssygdomme - Google Patents

Anvendelse af muterede antitrombiner til behandling eller forebyggelse af koagulationssygdomme

Info

Publication number
DK2175877T3
DK2175877T3 DK08786266.0T DK08786266T DK2175877T3 DK 2175877 T3 DK2175877 T3 DK 2175877T3 DK 08786266 T DK08786266 T DK 08786266T DK 2175877 T3 DK2175877 T3 DK 2175877T3
Authority
DK
Denmark
Prior art keywords
prevention
treatment
coagulation disorders
mutated antithrombin
antithrombin
Prior art date
Application number
DK08786266.0T
Other languages
English (en)
Inventor
Delphine Borgel-Botbol
Veronique Feger-Picard
Elsa Bianchini
Original Assignee
Univ Paris Sud Xi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Paris Sud Xi filed Critical Univ Paris Sud Xi
Application granted granted Critical
Publication of DK2175877T3 publication Critical patent/DK2175877T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8128—Antithrombin III
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK08786266.0T 2007-07-20 2008-07-18 Anvendelse af muterede antitrombiner til behandling eller forebyggelse af koagulationssygdomme DK2175877T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07290913 2007-07-20
PCT/EP2008/059486 WO2009013251A1 (en) 2007-07-20 2008-07-18 Use of mutated antithrombins for treating or preventing coagulation disorders

Publications (1)

Publication Number Publication Date
DK2175877T3 true DK2175877T3 (da) 2012-04-16

Family

ID=39111552

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08786266.0T DK2175877T3 (da) 2007-07-20 2008-07-18 Anvendelse af muterede antitrombiner til behandling eller forebyggelse af koagulationssygdomme

Country Status (7)

Country Link
US (1) US8741844B2 (da)
EP (1) EP2175877B1 (da)
JP (1) JP2010533684A (da)
AT (1) ATE539764T1 (da)
CA (1) CA2694047C (da)
DK (1) DK2175877T3 (da)
WO (1) WO2009013251A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010081878A1 (en) * 2009-01-16 2010-07-22 Universite Paris-Sud Xi Mutated antithrombins, a process for preparing the same and their use as drugs
US20140356377A1 (en) * 2011-08-25 2014-12-04 Umc Utrecht Holding B.V. Compounds for use in boosting coagulation
US9127274B2 (en) * 2012-04-26 2015-09-08 Alnylam Pharmaceuticals, Inc. Serpinc1 iRNA compositions and methods of use thereof
US9593166B2 (en) 2013-03-14 2017-03-14 Bayer Healthcare Llc Monoclonal antibodies against antithrombin β
GB201322091D0 (en) 2013-12-13 2014-01-29 Cambridge Entpr Ltd Modified serpins for the treatment of bleeding disorders
EP3904519A1 (en) 2014-10-30 2021-11-03 Genzyme Corporation Polynucleotide agents targeting serpinc1 (at3) and methods of use thereof
SG11201804729RA (en) 2015-12-07 2018-07-30 Genzyme Corp Methods and compositions for treating a serpinc1-associated disorder
ES2992695B2 (es) * 2023-06-15 2025-07-23 Fundacion Para La Formacion E Investig Sanitarias De La Region De Murcia [Ffiis Antidoto

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3901917A1 (de) * 1989-01-24 1990-07-26 Behringwerke Ag Mutanten von humanem antithrombin iii
JP3479539B2 (ja) * 1992-04-10 2003-12-15 エーザイ株式会社 ヒトアンチトロンビンｉｉｉ変異体
JPH0971600A (ja) * 1995-09-06 1997-03-18 Eisai Co Ltd ヒトアンチトロンビンｉｉｉ 変異体
AU782069B2 (en) * 1999-05-13 2005-06-30 Gtc Biotherapeutics, Inc. Transgenically produced antithrombin III and mutants thereof
US20060198836A1 (en) * 2003-07-17 2006-09-07 Smithkline Beecham Corporation Method of treating hit patients with argatroban

Also Published As

Publication number Publication date
ATE539764T1 (de) 2012-01-15
US20100298224A1 (en) 2010-11-25
JP2010533684A (ja) 2010-10-28
CA2694047A1 (en) 2009-01-29
EP2175877A1 (en) 2010-04-21
US8741844B2 (en) 2014-06-03
CA2694047C (en) 2018-01-30
EP2175877B1 (en) 2012-01-04
WO2009013251A1 (en) 2009-01-29

Similar Documents

Publication Publication Date Title
ES2352576T8 (es) Inhibidores de la replicación del virus de la inmunodeficiencia humana.
DK2375907T3 (da) Behandling af sygdomme, lidelser eller tilstande i lungerne under anvendelse af placentaceller
CY1121203T1 (el) Θεραπευτικες χρησεις της εμπαγλιφλοζινης
PT2323642E (pt) Utilização de edta+trometamina ou de fotoiativadores, associados a riboflavina para reticulação da córnea no tratamento de ceratocone ou de outros distúrbios ectásicos da córnea
AU2018253580A1 (en) Compositions, methods and uses for the treatment of diabetes and related conditions by controlling blood glucose level
CY1112813T1 (el) 4-(4-κυανο-2-θειοαρυλ)διϋδροπυριμιδινονες και η χρηση αυτων
WO2009108856A3 (en) Microrna signatures associated with human chronic lymphocytic leukemia (ccl) and uses thereof
AU2011274619A8 (en) miRNA and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated BRAF pathway
GT201400033A (es) Pirimidinas anilladas sustituidas y uso de las mismas
AU2012205878A8 (en) miRNA for treating diseases and conditions associated with neo-angiogenesis
BRPI0808775A2 (pt) compostos e composições como moduladores de atividade de gpr119
UA102065C2 (xx) Заміщені 4-арил-1,4-дигідро-1,6-нафтиридинаміди і їх застосування$замещенные 4-арил-1,4-дигидро-1,6-нафтиридинамиды и их применение
EA201001329A1 (ru) Соединения и композиции в качестве модуляторов активности gpr119
EA201001402A1 (ru) Фармацевтические растворы, способ получения и терапевтическое применение
EA201400119A1 (ru) Фармацевтическая композиция, способы лечения и их применение
HRP20181727T1 (hr) Upotreba protutijela protiv čimbenika xi, namijenjena sprečavanju ili liječenju stvaranja krvnog ugruška
MX356210B (es) Formulaciones de polimero acrilico.
EA201001332A1 (ru) Соединения и композиции в качестве модуляторов активности gpr119
EA201001330A1 (ru) Соединения и композиции в качестве модуляторов активности gpr119
IT1395519B1 (it) Pezzo composito, nonche' impiego del pezzo composito
EA201600442A1 (ru) Мягкая фармацевтическая композиция на водной основе, содержащая тапентадол
JO2581B1 (en) Substituted Arylsulfonamides
ZA201402745B (en) Blood coagulation factor vii and viia derivatives, conjugates and complexes comprising the same, and the use thereof.
MX356728B (es) Combinación farmacéutica para usar en el tratamiento de pacientes que padecen diabetes de tipo 2.
CR20110552A (es) Tratamiento de transtornos resistentes a la insulina