DK2195457T3 - Enkeltcellebaseret reporterassay til overvågning afgenekspressionsmønstre med høj spatiotemporal opløsning - Google Patents
Enkeltcellebaseret reporterassay til overvågning afgenekspressionsmønstre med høj spatiotemporal opløsningInfo
- Publication number
- DK2195457T3 DK2195457T3 DK08804165.2T DK08804165T DK2195457T3 DK 2195457 T3 DK2195457 T3 DK 2195457T3 DK 08804165 T DK08804165 T DK 08804165T DK 2195457 T3 DK2195457 T3 DK 2195457T3
- Authority
- DK
- Denmark
- Prior art keywords
- gene expression
- expression patterns
- reporter assay
- monitoring high
- cell reporter
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07291093A EP2036989B1 (en) | 2007-09-12 | 2007-09-12 | Polynucleotide suitable for single cell based reporter assay to monitor gene expression patterns with high spatio-temporal resolution |
| PCT/EP2008/062204 WO2009065635A1 (en) | 2007-09-12 | 2008-09-12 | Single cell based reporter assay to monitor gene expression patterns with high spatio-temporal resolution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2195457T3 true DK2195457T3 (da) | 2012-10-29 |
Family
ID=38962162
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07291093.8T DK2036989T3 (da) | 2007-09-12 | 2007-09-12 | Polynukleotid, der er egnet til enkeltcellebaseret reporterassay tilovervågning af genekspressionsmønstre med høj spatiotemporalopløsning |
| DK08804165.2T DK2195457T3 (da) | 2007-09-12 | 2008-09-12 | Enkeltcellebaseret reporterassay til overvågning afgenekspressionsmønstre med høj spatiotemporal opløsning |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07291093.8T DK2036989T3 (da) | 2007-09-12 | 2007-09-12 | Polynukleotid, der er egnet til enkeltcellebaseret reporterassay tilovervågning af genekspressionsmønstre med høj spatiotemporalopløsning |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9663833B2 (da) |
| EP (2) | EP2036989B1 (da) |
| JP (1) | JP2010538628A (da) |
| AU (1) | AU2008328177B2 (da) |
| CA (1) | CA2699358C (da) |
| DK (2) | DK2036989T3 (da) |
| ES (2) | ES2391906T3 (da) |
| PL (2) | PL2036989T3 (da) |
| WO (1) | WO2009065635A1 (da) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| AU2012236200B2 (en) * | 2011-03-30 | 2015-05-14 | Verinata Health, Inc. | Method for verifying bioassay samples |
| WO2012162260A2 (en) | 2011-05-21 | 2012-11-29 | Kdt, Llc. | Transgenic biosensors |
| CA2865575C (en) | 2012-02-27 | 2024-01-16 | Cellular Research, Inc. | Compositions and kits for molecular counting |
| GB2525568B (en) | 2013-03-15 | 2020-10-14 | Abvitro Llc | Single cell barcoding for antibody discovery |
| KR102758333B1 (ko) | 2013-08-28 | 2025-01-23 | 벡톤 디킨슨 앤드 컴퍼니 | 대량의 동시 단일 세포 분석 |
| TWI493036B (zh) * | 2013-12-24 | 2015-07-21 | Ind Tech Res Inst | 含一cd54表現之報導系統之免疫細胞的應用以及一經選殖之新穎細胞 |
| DK3089822T3 (da) * | 2013-12-30 | 2022-05-02 | Atreca Inc | Analyse af nukleinsyrer associeret med enkelte celler under anvendelse af nukleinsyrestregkoder |
| EP3950944A1 (en) | 2014-09-15 | 2022-02-09 | AbVitro LLC | High-throughput nucleotide library sequencing |
| WO2016049544A1 (en) | 2014-09-25 | 2016-03-31 | Northwestern University | Devices, methods, and systems relating to super resolution imaging |
| US20210166320A1 (en) | 2014-10-06 | 2021-06-03 | State Farm Mutual Automobile Insurance Company | System and method for obtaining and/or maintaining insurance coverage |
| US20210357481A1 (en) | 2014-10-06 | 2021-11-18 | State Farm Mutual Automobile Insurance Company | Medical diagnostic-initiated insurance offering |
| US10713728B1 (en) | 2014-10-06 | 2020-07-14 | State Farm Mutual Automobile Insurance Company | Risk mitigation for affinity groupings |
| US11574368B1 (en) | 2014-10-06 | 2023-02-07 | State Farm Mutual Automobile Insurance Company | Risk mitigation for affinity groupings |
| US10664920B1 (en) | 2014-10-06 | 2020-05-26 | State Farm Mutual Automobile Insurance Company | Blockchain systems and methods for providing insurance coverage to affinity groups |
| WO2016138496A1 (en) | 2015-02-27 | 2016-09-01 | Cellular Research, Inc. | Spatially addressable molecular barcoding |
| WO2016149422A1 (en) * | 2015-03-16 | 2016-09-22 | The Broad Institute, Inc. | Encoding of dna vector identity via iterative hybridization detection of a barcode transcript |
| WO2016160844A2 (en) | 2015-03-30 | 2016-10-06 | Cellular Research, Inc. | Methods and compositions for combinatorial barcoding |
| EP4582556A3 (en) | 2015-04-23 | 2025-10-08 | Becton, Dickinson and Company | Methods and compositions for whole transcriptome amplification |
| JP2016208851A (ja) * | 2015-04-30 | 2016-12-15 | 国立大学法人東北大学 | Tlr刺激物質の検出方法 |
| JP6940484B2 (ja) | 2015-09-11 | 2021-09-29 | セルラー リサーチ, インコーポレイテッド | ライブラリー正規化のための方法および組成物 |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| CN109791157B (zh) * | 2016-09-26 | 2022-06-07 | 贝克顿迪金森公司 | 使用具有条形码化的寡核苷酸序列的试剂测量蛋白质表达 |
| EP4556575A3 (en) | 2016-11-21 | 2025-10-08 | Bruker Spatial Biology, Inc. | A method for sequencing nucleic acids |
| CN110382708A (zh) | 2017-02-01 | 2019-10-25 | 赛卢拉研究公司 | 使用阻断性寡核苷酸进行选择性扩增 |
| CN110719959B (zh) | 2017-06-05 | 2021-08-06 | 贝克顿迪金森公司 | 针对单细胞的样品索引 |
| EP4491743A3 (en) * | 2018-03-02 | 2025-03-19 | Life Technologies Corporation | Novel quencher and reporter dye combinations |
| JP7358388B2 (ja) | 2018-05-03 | 2023-10-10 | ベクトン・ディキンソン・アンド・カンパニー | 反対側の転写物末端における分子バーコーディング |
| CN112272710A (zh) | 2018-05-03 | 2021-01-26 | 贝克顿迪金森公司 | 高通量多组学样品分析 |
| EP3794146B1 (en) | 2018-05-14 | 2025-12-10 | Bruker Spatial Biology, Inc. | Method for identifying a predetermined nucleotide sequence |
| WO2019222284A1 (en) * | 2018-05-14 | 2019-11-21 | The Broad Institute, Inc. | In situ cell screening methods and systems |
| US20210317527A1 (en) * | 2018-08-27 | 2021-10-14 | The Regents Of The University Of California | Reporter nucleic acids for type v crispr-mediated detection |
| US20210346401A1 (en) * | 2018-09-25 | 2021-11-11 | Yichang Humanwell Pharmaceutical Co., Ltd | Regulator of tgr5 signaling as immunomodulatory agent |
| ES2992135T3 (es) | 2018-10-01 | 2024-12-09 | Becton Dickinson Co | Determinar secuencias de transcripción 5 |
| US11932849B2 (en) | 2018-11-08 | 2024-03-19 | Becton, Dickinson And Company | Whole transcriptome analysis of single cells using random priming |
| US11492660B2 (en) | 2018-12-13 | 2022-11-08 | Becton, Dickinson And Company | Selective extension in single cell whole transcriptome analysis |
| ES2945227T3 (es) | 2019-01-23 | 2023-06-29 | Becton Dickinson Co | Oligonucleótidos asociados con anticuerpos |
| WO2020167920A1 (en) | 2019-02-14 | 2020-08-20 | Cellular Research, Inc. | Hybrid targeted and whole transcriptome amplification |
| US11965208B2 (en) | 2019-04-19 | 2024-04-23 | Becton, Dickinson And Company | Methods of associating phenotypical data and single cell sequencing data |
| CN120099137A (zh) | 2019-07-22 | 2025-06-06 | 贝克顿迪金森公司 | 单细胞染色质免疫沉淀测序测定 |
| JP7522189B2 (ja) | 2019-11-08 | 2024-07-24 | ベクトン・ディキンソン・アンド・カンパニー | 免疫レパートリーシーケンシングのための完全長v(d)j情報を得るためのランダムプライミングの使用 |
| US11649497B2 (en) | 2020-01-13 | 2023-05-16 | Becton, Dickinson And Company | Methods and compositions for quantitation of proteins and RNA |
| WO2021146219A1 (en) | 2020-01-13 | 2021-07-22 | Becton, Dickinson And Company | Cell capture using du-containing oligonucleotides |
| WO2021155057A1 (en) | 2020-01-29 | 2021-08-05 | Becton, Dickinson And Company | Barcoded wells for spatial mapping of single cells through sequencing |
| WO2021173719A1 (en) | 2020-02-25 | 2021-09-02 | Becton, Dickinson And Company | Bi-specific probes to enable the use of single-cell samples as single color compensation control |
| US11661625B2 (en) | 2020-05-14 | 2023-05-30 | Becton, Dickinson And Company | Primers for immune repertoire profiling |
| US12157913B2 (en) | 2020-06-02 | 2024-12-03 | Becton, Dickinson And Company | Oligonucleotides and beads for 5 prime gene expression assay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| US12391940B2 (en) | 2020-07-31 | 2025-08-19 | Becton, Dickinson And Company | Single cell assay for transposase-accessible chromatin |
| EP4247967A1 (en) | 2020-11-20 | 2023-09-27 | Becton, Dickinson and Company | Profiling of highly expressed and lowly expressed proteins |
| JP2023554368A (ja) * | 2020-12-15 | 2023-12-27 | クアンタム-エスアイ インコーポレイテッド | 単一分子速度論による分子バーコード分析 |
| CN116685850A (zh) | 2020-12-15 | 2023-09-01 | 贝克顿迪金森公司 | 单细胞分泌组分析 |
| CN115479923B (zh) * | 2021-05-31 | 2024-06-18 | 北京大学 | 一种基于荧光共振能量转移的活细胞单分子rna标记方法 |
| US12163190B2 (en) | 2022-06-17 | 2024-12-10 | Insitro, Inc. | In situ sequencing of RNA transcripts with non-uniform 5 prime ends |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3572799A (en) * | 1998-04-24 | 1999-11-16 | Genova Pharmaceuticals Corporation | Function-based gene discovery |
| US6203986B1 (en) * | 1998-10-22 | 2001-03-20 | Robert H. Singer | Visualization of RNA in living cells |
| US6692965B1 (en) * | 1999-11-23 | 2004-02-17 | Chromocell Corporation | Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences |
| AU2001245945A1 (en) * | 2000-03-23 | 2001-10-03 | Pe Corporation (Ny) | Detection kits, such as nucleic acid arrays, for detecting the expression of 10,000 or more drosophila genes and uses thereof |
| WO2004027028A2 (en) * | 2002-09-18 | 2004-04-01 | The Trustees Of The University Of Pennsylvania | Compositions, methods and kits for detection of an antigen on a cell and in a biological mixture |
| US7829278B2 (en) * | 2004-10-28 | 2010-11-09 | Board Of Trustees Of The University Of Illinois | Polynucleotide barcoding |
-
2007
- 2007-09-12 EP EP07291093A patent/EP2036989B1/en not_active Not-in-force
- 2007-09-12 PL PL07291093T patent/PL2036989T3/pl unknown
- 2007-09-12 DK DK07291093.8T patent/DK2036989T3/da active
- 2007-09-12 ES ES07291093T patent/ES2391906T3/es active Active
-
2008
- 2008-09-12 WO PCT/EP2008/062204 patent/WO2009065635A1/en not_active Ceased
- 2008-09-12 CA CA2699358A patent/CA2699358C/en not_active Expired - Fee Related
- 2008-09-12 DK DK08804165.2T patent/DK2195457T3/da active
- 2008-09-12 PL PL08804165T patent/PL2195457T3/pl unknown
- 2008-09-12 JP JP2010524516A patent/JP2010538628A/ja active Pending
- 2008-09-12 ES ES08804165T patent/ES2392005T3/es active Active
- 2008-09-12 AU AU2008328177A patent/AU2008328177B2/en not_active Ceased
- 2008-09-12 US US12/676,135 patent/US9663833B2/en not_active Expired - Fee Related
- 2008-09-12 EP EP08804165A patent/EP2195457B1/en not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP2195457B1 (en) | 2012-07-25 |
| WO2009065635A1 (en) | 2009-05-28 |
| AU2008328177A1 (en) | 2009-05-28 |
| EP2036989B1 (en) | 2012-07-25 |
| CA2699358A1 (en) | 2009-05-28 |
| CA2699358C (en) | 2017-11-21 |
| JP2010538628A (ja) | 2010-12-16 |
| ES2392005T3 (es) | 2012-12-03 |
| PL2036989T3 (pl) | 2012-12-31 |
| PL2195457T3 (pl) | 2012-12-31 |
| EP2195457A1 (en) | 2010-06-16 |
| EP2036989A1 (en) | 2009-03-18 |
| AU2008328177B2 (en) | 2015-01-22 |
| DK2036989T3 (da) | 2012-10-22 |
| US9663833B2 (en) | 2017-05-30 |
| ES2391906T3 (es) | 2012-11-30 |
| US20110021369A1 (en) | 2011-01-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK2195457T3 (da) | Enkeltcellebaseret reporterassay til overvågning afgenekspressionsmønstre med høj spatiotemporal opløsning | |
| DK2497834T4 (da) | Fremgangsmåde til påvisning af methyleringen af colon-cancer-specifikke methyleringsmarkørgener til colon-cancer-diagnose | |
| DK2129797T3 (da) | Nukleinsyrepåvisning | |
| EP2139616A4 (en) | NEW ELECTRODE | |
| BRPI0811503A2 (pt) | Diagnótico de melanoma por análise de ácido nucleico | |
| DE602007003881D1 (de) | Intraperikardiale Elektrode | |
| DE602008005237D1 (de) | Tintenstrahlaufzeichnungsverfahren | |
| DK2344682T3 (da) | Elektrode for elektrolysecelle | |
| DK2061766T3 (da) | Nye forbindelser | |
| SMT201600131B (it) | Procedimento per la produzione di piastrine | |
| EP2344029A4 (en) | Electrode system | |
| BRPI0817781A2 (pt) | piperazino-diidroteinopirimidinas substituídas com heterociclo | |
| EP2519522A4 (en) | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | |
| DK2250161T3 (da) | Forbindelser med CRTH2-antagonistaktivitet | |
| EP2114634A4 (en) | TESTING HEAD MANIPULATOR | |
| BRPI0921710A2 (pt) | relatório de medição de células vizinhas | |
| DK3564240T3 (da) | Piperidinmellemprodukter | |
| DK2120936T3 (da) | Nye fremgangsmåder | |
| DK2234976T3 (da) | Nye pyrazol-substituerede arylamider | |
| DK1991541T3 (da) | Nye pyron-indolderivater samt fremgangsmåde til deres fremstilling | |
| DK2074123T3 (da) | Nye anxiolytiske forbindelser | |
| EP2117306A4 (en) | NEUROGENIC COMPOUNDS | |
| EP2266301A4 (en) | ACTIVITY MESSAGE FOR CUTTING APPLICATIONS | |
| EP2514426A4 (en) | CONNECTION WITH ANTI-INFLAMMATORY EFFECT | |
| EP2192402A4 (en) | Enzyme electrode |