DK2200980T3 - Aminoarylsulfonamidforbindelser og deres anvendelse som 5-HT6-ligander - Google Patents

Aminoarylsulfonamidforbindelser og deres anvendelse som 5-HT6-ligander

Info

Publication number
DK2200980T3
DK2200980T3 DK08776656.4T DK08776656T DK2200980T3 DK 2200980 T3 DK2200980 T3 DK 2200980T3 DK 08776656 T DK08776656 T DK 08776656T DK 2200980 T3 DK2200980 T3 DK 2200980T3
Authority
DK
Denmark
Prior art keywords
compounds
pharmaceutically acceptable
disorders
stereoisomers
derivatives
Prior art date
Application number
DK08776656.4T
Other languages
English (en)
Inventor
Nirogi Venkata Satya Ramakrishna
Rama Sastri Kambhampati
Anil Karbhari Shinde
Nagaraj Vishwottam Kandikere
Venkateswarlu Jasti
Original Assignee
Suven Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd
Application granted granted Critical
Publication of DK2200980T3 publication Critical patent/DK2200980T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
DK08776656.4T 2007-10-26 2008-05-02 Aminoarylsulfonamidforbindelser og deres anvendelse som 5-HT6-ligander DK2200980T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2433CH2007 2007-10-26
PCT/IN2008/000281 WO2009053997A1 (en) 2007-10-26 2008-05-02 Amino arylsulfonamide compounds and their use as 5-ht6 ligands

Publications (1)

Publication Number Publication Date
DK2200980T3 true DK2200980T3 (da) 2011-11-21

Family

ID=39769531

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08776656.4T DK2200980T3 (da) 2007-10-26 2008-05-02 Aminoarylsulfonamidforbindelser og deres anvendelse som 5-HT6-ligander

Country Status (20)

Country Link
US (1) US7964627B2 (da)
EP (1) EP2200980B9 (da)
JP (1) JP5236001B2 (da)
KR (1) KR101268654B1 (da)
CN (1) CN101835748B (da)
AT (1) ATE518833T1 (da)
AU (1) AU2008315309B2 (da)
BR (1) BRPI0816571A2 (da)
CA (1) CA2703157C (da)
CY (1) CY1112181T1 (da)
DK (1) DK2200980T3 (da)
EA (1) EA017154B1 (da)
ES (1) ES2370680T3 (da)
HR (1) HRP20110780T2 (da)
IL (1) IL205231A (da)
MX (1) MX2010003765A (da)
NZ (1) NZ585374A (da)
SI (1) SI2200980T1 (da)
WO (1) WO2009053997A1 (da)
ZA (1) ZA201002165B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102153884B (zh) * 2011-02-16 2013-06-19 连云港清泰化工有限公司 一种墨水型染料及其制备方法与用途
WO2013055386A2 (en) 2011-10-03 2013-04-18 The University Of Utah Research Foundation Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome
CN104220088A (zh) * 2012-02-02 2014-12-17 柯尔朗恩有限责任公司 酶组合物及其用于创伤愈合的用途
EP3083588B1 (en) 2013-12-20 2020-12-09 Sunshine Lake Pharma Co., Ltd. Aromatic heterocyclic compounds and their application in pharmaceuticals
DK3180001T3 (da) * 2014-08-16 2019-04-01 Suven Life Sciences Ltd Aktiv metabolit af 1-[(2-bromphenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1h-indol-dimesylat-monohydrat og dimesylat-dihydratsalt af aktivt metabolit

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DZ2376A1 (fr) 1996-12-19 2002-12-28 Smithkline Beecham Plc Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
EP0994862B1 (en) 1997-07-11 2005-06-01 SmithKline Beecham plc Sulphonamide derivatives being 5-ht6 receptor antagonists and process for their preparation
EP0930302B1 (en) * 1998-01-16 2003-04-02 F.Hoffmann-La Roche Ag Benzosulfone derivatives
GB9801392D0 (en) 1998-01-22 1998-03-18 Smithkline Beecham Plc Novel compounds
GB9803411D0 (en) 1998-02-18 1998-04-15 Smithkline Beecham Plc Novel compounds
ATE375990T1 (de) 1999-04-21 2007-11-15 Nps Allelix Corp Piperidin-indol derivate mit 5-ht6 affinität
GB9926302D0 (en) 1999-11-05 2000-01-12 Smithkline Beecham Plc Novel compounds
ATE340795T1 (de) 2001-01-30 2006-10-15 Lilly Co Eli Benzolsulfonsäureester-indol-5-yl als 5-ht6 rezeptor-antagonisten
CN100439370C (zh) 2001-02-08 2008-12-03 记忆药物公司 作为磷酸二酯酶4抑制剂的三氟甲基嘌呤
BR0210929A (pt) 2001-06-07 2004-06-08 Hoffmann La Roche Derivados de indol com afinidade para o receptor 5-ht6
WO2003065046A2 (en) 2002-02-01 2003-08-07 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with a new human 5-ht6 receptor
AU2003244452A1 (en) 2002-02-05 2003-09-02 Glaxo Group Limited Method of promoting neuronal growth
RU2309154C9 (ru) 2002-03-27 2016-09-27 Глэксо Груп Лимитед 3-фенилсульфонил-8-пиперазин-1-ил-хинолины, обладающие аффинностью к 5-нт6 рецептору, способы их получения (варианты)
RU2324693C2 (ru) * 2002-10-18 2008-05-20 Ф.Хоффманн-Ля Рош Аг 4-пиперазинилбензолсульфонилиндолы, характеризующиеся сродством к рецептору 5-нт6
JP4559230B2 (ja) 2002-11-28 2010-10-06 スベン ライフ サイエンシズ リミティド セロトニン受容体に対する親和性を有する新規ｎ−アリールスルホニル−３−置換されたインドール、その調製方法、それを含有する医薬組成物
MXPA05005700A (es) * 2002-11-28 2005-08-16 Suven Life Sciences Ltd N-arilsulfonil-3-aminoalcoxiindoles.
AU2003292508A1 (en) 2002-11-28 2004-06-18 Suven Life Sciences Limited N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands
EA009367B1 (ru) 2002-12-18 2007-12-28 Сувен Лайф Сайенсиз Лимитед ПРОИЗВОДНЫЕ 5-ТИА-5-ДИОКСО-4b-АЗАИНДЕНО[2,1-a]ИНДЕНА, ОБЛАДАЮЩИЕ АФФИННОСТЬЮ К РЕЦЕПТОРУ СЕРОТОНИНА
BRPI0520579B8 (pt) * 2005-08-12 2021-05-25 Suven Life Sciences Ltd composto, processo para a preparação de um composto e composição farmacêutica

Also Published As

Publication number Publication date
CA2703157C (en) 2013-02-05
HRP20110780T1 (hr) 2011-11-30
ZA201002165B (en) 2011-05-25
CA2703157A1 (en) 2009-04-30
CN101835748A (zh) 2010-09-15
EA017154B1 (ru) 2012-10-30
EP2200980B9 (en) 2011-12-28
US20100216861A1 (en) 2010-08-26
EP2200980B1 (en) 2011-08-03
WO2009053997A1 (en) 2009-04-30
NZ585374A (en) 2011-09-30
ES2370680T3 (es) 2011-12-21
AU2008315309A1 (en) 2009-04-30
HK1147750A1 (en) 2011-08-19
MX2010003765A (es) 2010-04-30
US7964627B2 (en) 2011-06-21
JP5236001B2 (ja) 2013-07-17
BRPI0816571A2 (pt) 2015-12-22
EA201070527A1 (ru) 2010-10-29
CN101835748B (zh) 2012-11-14
KR101268654B1 (ko) 2013-05-29
CY1112181T1 (el) 2015-12-09
SI2200980T1 (sl) 2011-12-30
ES2370680T9 (es) 2012-02-15
AU2008315309B2 (en) 2011-06-09
KR20100069707A (ko) 2010-06-24
JP2011500792A (ja) 2011-01-06
IL205231A (en) 2014-03-31
HRP20110780T2 (hr) 2018-06-29
EP2200980A1 (en) 2010-06-30
ATE518833T1 (de) 2011-08-15
IL205231A0 (en) 2010-12-30

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