DK2205618T3 - Syntetiske 5' ikke-translaterede regioner, ekspressionsvektorer og fremgangsmåder til forøgelse af transgen ekspression - Google Patents

Syntetiske 5' ikke-translaterede regioner, ekspressionsvektorer og fremgangsmåder til forøgelse af transgen ekspression Download PDF

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Publication number: DK2205618T3
Authority: DK; Denmark
Prior art keywords: sequence; gene; seq; utr; synthetic
Prior art date: 2007-09-26

Application number

DK08833086.5T

Other languages

English (en)

Inventor

Thomas Reed

Original Assignee

Intrexon Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-09-26

Filing date

2008-09-26

Publication date

2017-02-20

2008-09-26 Application filed by Intrexon Corp filed Critical Intrexon Corp

2017-02-20 Application granted granted Critical

2017-02-20 Publication of DK2205618T3 publication Critical patent/DK2205618T3/da

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- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4732—Casein
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
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- C12N2830/00—Vector systems having a special element relevant for transcription

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DK08833086.5T 2007-09-26 2008-09-26 Syntetiske 5' ikke-translaterede regioner, ekspressionsvektorer og fremgangsmåder til forøgelse af transgen ekspression DK2205618T3 (da)

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US97540707P	2007-09-26	2007-09-26
PCT/US2008/078028 WO2009042971A2 (en)	2007-09-26	2008-09-26	Synthetic 5'utrs, expression vectors, and methods for increasing transgene expression

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DK16184100.2T DK3156414T3 (da)	2007-09-26	2008-09-26	Syntetisk 5'utrs ekspressionsvektorer og fremgangsmåder til øgning af transgen ekspression

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US (1)	US8835621B2 (da)
EP (3)	EP2535419A3 (da)
JP (1)	JP5514727B2 (da)
KR (1)	KR101541935B1 (da)
CN (1)	CN101855233B (da)
AU (1)	AU2008304201C1 (da)
BR (1)	BRPI0817231B1 (da)
CA (1)	CA2715078C (da)
DK (2)	DK2205618T3 (da)
ES (1)	ES2614402T3 (da)
HU (1)	HUE031422T2 (da)
IL (1)	IL204730A (da)
MX (1)	MX2010003369A (da)
RU (1)	RU2524431C2 (da)
WO (1)	WO2009042971A2 (da)

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Publication number	Publication date
ES2614402T3 (es)	2017-05-31
IL204730A (en)	2014-01-30
CA2715078A1 (en)	2009-04-02
EP2535419A2 (en)	2012-12-19
CA2715078C (en)	2019-07-23
EP2535419A3 (en)	2013-05-29
AU2008304201C1 (en)	2015-02-05
WO2009042971A3 (en)	2009-05-14
JP5514727B2 (ja)	2014-06-04
EP3156414A1 (en)	2017-04-19
BRPI0817231B1 (pt)	2020-06-09
BRPI0817231A2 (pt)	2015-06-16
IL204730A0 (en)	2010-11-30
EP2205618A2 (en)	2010-07-14
WO2009042971A8 (en)	2009-07-16
KR101541935B1 (ko)	2015-08-05
US20100293625A1 (en)	2010-11-18
RU2010116782A (ru)	2011-11-10
DK3156414T3 (da)	2020-03-09
KR20100085935A (ko)	2010-07-29
EP2205618B1 (en)	2016-11-09
MX2010003369A (es)	2010-05-05
CN101855233B (zh)	2014-05-07
EP2205618A4 (en)	2011-02-02
EP3156414B1 (en)	2019-12-04
HUE031422T2 (en)	2017-07-28
AU2008304201A1 (en)	2009-04-02
CN101855233A (zh)	2010-10-06
RU2524431C2 (ru)	2014-07-27
AU2008304201B2 (en)	2014-08-14
JP2010539946A (ja)	2010-12-24
US8835621B2 (en)	2014-09-16
WO2009042971A2 (en)	2009-04-02

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