DK2307042T3 - Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte - Google Patents
Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerteInfo
- Publication number
- DK2307042T3 DK2307042T3 DK09768854.3T DK09768854T DK2307042T3 DK 2307042 T3 DK2307042 T3 DK 2307042T3 DK 09768854 T DK09768854 T DK 09768854T DK 2307042 T3 DK2307042 T3 DK 2307042T3
- Authority
- DK
- Denmark
- Prior art keywords
- trpv
- pain
- module
- treatment
- receptor system
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7562708P | 2008-06-25 | 2008-06-25 | |
| DKPA200800880 | 2008-06-25 | ||
| PCT/DK2009/050143 WO2009155932A2 (en) | 2008-06-25 | 2009-06-24 | Modulation of the trpv : vps10p-domain receptor system for the treatment of pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2307042T3 true DK2307042T3 (da) | 2014-05-12 |
Family
ID=41445008
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09768854.3T DK2307042T3 (da) | 2008-06-25 | 2009-06-24 | Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte |
| DK14154831.3T DK2732823T3 (da) | 2008-06-25 | 2009-06-24 | Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14154831.3T DK2732823T3 (da) | 2008-06-25 | 2009-06-24 | Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8460657B2 (da) |
| EP (2) | EP2307042B1 (da) |
| DK (2) | DK2307042T3 (da) |
| ES (1) | ES2464459T3 (da) |
| WO (1) | WO2009155932A2 (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004085648A2 (en) | 2003-03-19 | 2004-10-07 | Biogen Idec Ma Inc. | Nogo receptor binding protein |
| PT1776136E (pt) | 2004-06-24 | 2012-12-05 | Biogen Idec Inc | Tratamento de estados que envolvem desmielinização |
| SI1904104T1 (sl) | 2005-07-08 | 2013-12-31 | Biogen Idec Ma Inc. | Protitelesa SP35 in njihova uporaba |
| JP2009544703A (ja) * | 2006-07-24 | 2009-12-17 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Sp35またはTrkAアンタゴニストの投与により髄鞘形成、ニューロンの生存および希乏突起膠細胞の分化を促進するための方法 |
| EP3225251B1 (en) * | 2006-12-21 | 2020-02-12 | H. Lundbeck A/S | Modulation of activity of proneurotrophins |
| WO2009048605A1 (en) * | 2007-10-11 | 2009-04-16 | Biogen Idec Ma Inc. | Methods for treating pressure induced optic neuropathy, preventing neuronal degeneration and promoting neuronal cell, survival via administration of lingo-1 antagonists and trkb agonists |
| CA2702630C (en) * | 2007-11-08 | 2017-11-21 | Biogen Idec Ma Inc. | Use of lingo-4 antagonists in the treatment of conditions involving demyelination |
| US9751947B2 (en) | 2008-02-04 | 2017-09-05 | Lay Line Genomics S.P.A. | Antibodies and derivatives thereof |
| DK2982695T3 (da) | 2008-07-09 | 2019-05-13 | Biogen Ma Inc | Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf |
| WO2011157275A1 (en) * | 2010-06-14 | 2011-12-22 | H. Lundbeck A/S | Modulation of the interaction between sorla and gdnf-family ligand receptors |
| JP6190723B2 (ja) | 2010-12-01 | 2017-08-30 | アルダーバイオ ホールディングス エルエルシー | 抗ngf組成物およびその使用 |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| CN104470541A (zh) | 2012-05-14 | 2015-03-25 | 比奥根艾迪克Ma公司 | 用于治疗涉及运动神经元的疾患的lingo-2拮抗剂 |
| CN104955456B (zh) | 2013-01-28 | 2018-07-03 | H.隆德贝克有限公司 | 作为分拣蛋白抑制剂的n-取代的-5-取代的邻氨甲酰苯甲酸 |
| ES2925071T3 (es) | 2013-02-08 | 2022-10-13 | Gen Mills Inc | Productos alimentarios reducidos en sodio |
| US20160334391A1 (en) * | 2014-01-23 | 2016-11-17 | Biogaia Ab | Selection of Agents Modulating Gastrointestinal Pain |
| JP2018504400A (ja) | 2015-01-08 | 2018-02-15 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | Lingo‐1拮抗薬及び脱髄障害の治療のための使用 |
| CN107708733B (zh) | 2015-04-07 | 2022-11-15 | 艾利妥 | 抗分拣蛋白抗体和其使用方法 |
| US10849992B1 (en) | 2015-04-07 | 2020-12-01 | Alector Llc | Methods of screening for sortilin binding antagonists |
| EP3390435A1 (en) * | 2015-12-18 | 2018-10-24 | Aarhus Universitet | Sorcs peptides and uses thereof |
| TWI809147B (zh) | 2018-07-13 | 2023-07-21 | 美商阿列克特有限責任公司 | 抗分揀蛋白抗體及其使用方法 |
| GB201918103D0 (en) | 2019-12-10 | 2020-01-22 | Oblique Therapeutics Ab | Epitopes and antibodies |
| US20230248684A1 (en) * | 2020-05-28 | 2023-08-10 | Phor-Med, Inc. | Compositions and methods for treating acute respiratory distress syndrome (ards) and inflammatory disorders caused by coronaviruses and other respiratory pathogens or agents that mediate pulmonary injury, inflammation or acute respiratory distress, and related compositions and methods for treating and preventing human sars coronavirus infection, covid-19 disease and related symptoms |
| JP2025506481A (ja) | 2022-02-09 | 2025-03-11 | テイトゥル トロフィックス エーピーエス | 新規ペプチド |
| CN120309699B (zh) * | 2025-04-18 | 2025-11-21 | 中国医学科学院基础医学研究所 | 稀释诱导相分离多肽及其应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4474893A (en) | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4588580B2 (en) | 1984-07-23 | 1999-02-16 | Alaz Corp | Transdermal administration of fentanyl and device therefor |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4904475A (en) | 1985-05-03 | 1990-02-27 | Alza Corporation | Transdermal delivery of drugs from an aqueous reservoir |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US6071517A (en) | 1986-07-07 | 2000-06-06 | Medarex, Inc. | Bispecific heteroantibodies with dual effector functions |
| US4954617A (en) | 1986-07-07 | 1990-09-04 | Trustees Of Dartmouth College | Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes |
| US4881175A (en) | 1986-09-02 | 1989-11-14 | Genex Corporation | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4816258A (en) | 1987-02-26 | 1989-03-28 | Alza Corporation | Transdermal contraceptive formulations |
| US4788062A (en) | 1987-02-26 | 1988-11-29 | Alza Corporation | Transdermal administration of progesterone, estradiol esters, and mixtures thereof |
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| ATE243754T1 (de) | 1987-05-21 | 2003-07-15 | Micromet Ag | Multifunktionelle proteine mit vorbestimmter zielsetzung |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
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| WO1994013806A1 (en) | 1992-12-11 | 1994-06-23 | The Dow Chemical Company | Multivalent single chain antibodies |
| PT1231268E (pt) | 1994-01-31 | 2005-11-30 | Univ Boston | Bancos de anticorpos policlonais |
| US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| AU2003287930A1 (en) | 2002-12-20 | 2004-07-14 | Neuronicon Aps | Modulation of activity of neurotrophins |
| WO2007100718A2 (en) * | 2006-02-24 | 2007-09-07 | Denise Barbut | Neurotensin receptor agonists and opioid receptor agonists |
| EP3225251B1 (en) * | 2006-12-21 | 2020-02-12 | H. Lundbeck A/S | Modulation of activity of proneurotrophins |
| WO2009132656A2 (en) * | 2008-04-27 | 2009-11-05 | H. Lundbeck A/S | Design of specific ligands to sortilin |
-
2009
- 2009-06-24 US US13/000,854 patent/US8460657B2/en not_active Expired - Fee Related
- 2009-06-24 ES ES09768854.3T patent/ES2464459T3/es active Active
- 2009-06-24 EP EP09768854.3A patent/EP2307042B1/en active Active
- 2009-06-24 DK DK09768854.3T patent/DK2307042T3/da active
- 2009-06-24 WO PCT/DK2009/050143 patent/WO2009155932A2/en not_active Ceased
- 2009-06-24 DK DK14154831.3T patent/DK2732823T3/da active
- 2009-06-24 EP EP14154831.3A patent/EP2732823B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009155932A2 (en) | 2009-12-30 |
| US8460657B2 (en) | 2013-06-11 |
| ES2464459T3 (es) | 2014-06-02 |
| US20110142830A1 (en) | 2011-06-16 |
| EP2732823B1 (en) | 2019-08-07 |
| DK2732823T3 (da) | 2019-09-16 |
| EP2732823A1 (en) | 2014-05-21 |
| EP2307042B1 (en) | 2014-03-26 |
| EP2307042A2 (en) | 2011-04-13 |
| WO2009155932A3 (en) | 2010-04-22 |
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