DK231985A - Fremgangsmaade til fremstilling af rimantadin - Google Patents

Fremgangsmaade til fremstilling af rimantadin Download PDF

Info

Publication number: DK231985A
Authority: DK; Denmark
Prior art keywords: rimantadine; pressure; procedure; preparation; low temperature
Prior art date: 1984-05-23

Application number

DK231985A

Other languages

English (en)

Other versions

DK231985D0 (da

DK170331B1 (da

Inventor

John Jih-Hua Liu

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-05-23

Filing date

1985-05-23

Publication date

1985-11-24

1985-05-23 Application filed by Du Pont filed Critical Du Pont

1985-05-23 Publication of DK231985D0 publication Critical patent/DK231985D0/da

1985-11-24 Publication of DK231985A publication Critical patent/DK231985A/da

1995-08-07 Application granted granted Critical

1995-08-07 Publication of DK170331B1 publication Critical patent/DK170331B1/da

Links

UBCHPRBFMUDMNC-UHFFFAOYSA-N 1-(1-adamantyl)ethanamine Chemical compound C1C(C2)CC3CC2CC1(C(N)C)C3 UBCHPRBFMUDMNC-UHFFFAOYSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
229960000888 rimantadine Drugs 0.000 title abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
NOWUKHMRBUCWRA-UHFFFAOYSA-N n-[1-(1-adamantyl)ethylidene]hydroxylamine Chemical compound C1C(C2)CC3CC2CC1(C(=NO)C)C3 NOWUKHMRBUCWRA-UHFFFAOYSA-N 0.000 abstract 1
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
- C07C209/40—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of hydroxylamino or oxyimino groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Catalysts (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Luminescent Compositions (AREA)
Heat Treatment Of Sheet Steel (AREA)
Materials For Medical Uses (AREA)
Infusion, Injection, And Reservoir Apparatuses (AREA)
Forging (AREA)

DK231985A 1984-05-23 1985-05-23 Fremgangsmåde til fremstilling af rimantadin DK170331B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/613,374 US4551552A (en)	1984-05-23	1984-05-23	Process for preparing rimantadine
US61337484		1984-05-23

Publications (3)

Publication Number	Publication Date
DK231985D0 DK231985D0 (da)	1985-05-23
DK231985A true DK231985A (da)	1985-11-24
DK170331B1 DK170331B1 (da)	1995-08-07

Family

ID=24457071

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK231985A DK170331B1 (da)	1984-05-23	1985-05-23	Fremgangsmåde til fremstilling af rimantadin

Country Status (20)

Country	Link
US (1)	US4551552A (da)
EP (1)	EP0162444B1 (da)
JP (1)	JPH0635423B2 (da)
AT (1)	ATE51395T1 (da)
AU (1)	AU569987B2 (da)
CA (1)	CA1220198A (da)
DE (1)	DE3576819D1 (da)
DK (1)	DK170331B1 (da)
ES (1)	ES8700223A1 (da)
FI (1)	FI85010C (da)
GR (1)	GR851257B (da)
HU (1)	HU194155B (da)
IE (1)	IE58285B1 (da)
IL (1)	IL75281A (da)
MX (1)	MX160131A (da)
NO (1)	NO161217C (da)
NZ (1)	NZ212157A (da)
PT (1)	PT80515B (da)
SU (1)	SU1327786A3 (da)
ZA (1)	ZA853892B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5019482A (en) *	1987-08-12	1991-05-28	Asahi Kasei Kogyo Kabushiki Kaisha	Polymer/oxime ester/coumarin compound photosensitive composition
US5326643A (en) *	1991-10-07	1994-07-05	International Business Machines Corporation	Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier
EP2316468A1 (en)	2002-02-22	2011-05-04	Shire LLC	Delivery system and methods for protecting and administering dextroamphetamine
BR112014005490A2 (pt)	2011-09-08	2017-06-13	Merz Pharma Gmbh & Co. Kgaa	uso de derivados de adamantano no tratamento de queratose actínica
US10583171B2 (en)	2015-11-30	2020-03-10	INSERM (Institut National de la Santé et de la Recherche Médicale)	NMDAR antagonists for the treatment of diseases associated with angiogenesis
RU2635991C2 (ru) *	2016-03-18	2017-11-17	Открытое акционерное общество "Ирбитский химико-фармацевтический завод"	Способ получения римантадина гидрохлорида

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3352912A (en) *	1963-07-24	1967-11-14	Du Pont	Adamantanes and tricyclo[4. 3. 1. 1 3.8] undecanes
FR5758M (da) *	1964-07-24	1968-02-05
US4100170A (en) *	1967-12-18	1978-07-11	Pennwalt Corporation	Anorectic adamantane derivatives and method of using the same
JPS5581841A (en) *	1978-12-15	1980-06-20	Kao Corp	1-(1-aminoalkyl)tricyclo 4.3.1.12,5 undecane

1984
- 1984-05-23 US US06/613,374 patent/US4551552A/en not_active Expired - Lifetime
1985
- 1985-05-20 AU AU42668/85A patent/AU569987B2/en not_active Ceased
- 1985-05-21 CA CA000481949A patent/CA1220198A/en not_active Expired
- 1985-05-21 GR GR851257A patent/GR851257B/el unknown
- 1985-05-21 EP EP85106207A patent/EP0162444B1/en not_active Expired - Lifetime
- 1985-05-21 AT AT85106207T patent/ATE51395T1/de not_active IP Right Cessation
- 1985-05-21 DE DE8585106207T patent/DE3576819D1/de not_active Expired - Lifetime
- 1985-05-21 SU SU853915007A patent/SU1327786A3/ru active
- 1985-05-22 ES ES543383A patent/ES8700223A1/es not_active Expired
- 1985-05-22 JP JP60108477A patent/JPH0635423B2/ja not_active Expired - Lifetime
- 1985-05-22 NZ NZ212157A patent/NZ212157A/en unknown
- 1985-05-22 HU HU851938A patent/HU194155B/hu not_active IP Right Cessation
- 1985-05-22 IL IL75281A patent/IL75281A/xx not_active IP Right Cessation
- 1985-05-22 MX MX6143A patent/MX160131A/es unknown
- 1985-05-22 ZA ZA853892A patent/ZA853892B/xx unknown
- 1985-05-22 FI FI852040A patent/FI85010C/fi not_active IP Right Cessation
- 1985-05-22 NO NO852039A patent/NO161217C/no unknown
- 1985-05-22 PT PT80515A patent/PT80515B/pt not_active IP Right Cessation
- 1985-05-22 IE IE127385A patent/IE58285B1/en not_active IP Right Cessation
- 1985-05-23 DK DK231985A patent/DK170331B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI852040L (fi)	1985-11-24
IE58285B1 (en)	1993-08-25
CA1220198A (en)	1987-04-07
FI85010C (fi)	1992-02-25
ZA853892B (en)	1987-01-28
MX160131A (es)	1989-12-06
PT80515A (en)	1985-06-01
ES8700223A1 (es)	1986-10-16
DK231985D0 (da)	1985-05-23
IE851273L (en)	1985-11-23
NZ212157A (en)	1988-04-29
ATE51395T1 (de)	1990-04-15
EP0162444A3 (en)	1986-11-26
HU194155B (en)	1988-01-28
FI852040A0 (fi)	1985-05-22
EP0162444A2 (en)	1985-11-27
PT80515B (pt)	1987-11-11
NO161217B (no)	1989-04-10
JPS60255754A (ja)	1985-12-17
EP0162444B1 (en)	1990-03-28
FI85010B (fi)	1991-11-15
NO161217C (no)	1989-07-19
IL75281A (en)	1988-06-30
IL75281A0 (en)	1985-09-29
DE3576819D1 (de)	1990-05-03
US4551552A (en)	1985-11-05
JPH0635423B2 (ja)	1994-05-11
AU569987B2 (en)	1988-02-25
HUT38896A (en)	1986-07-28
GR851257B (da)	1985-11-25
NO852039L (no)	1985-11-25
SU1327786A3 (ru)	1987-07-30
AU4266885A (en)	1985-11-28
DK170331B1 (da)	1995-08-07
ES543383A0 (es)	1986-10-16

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Legal Events

Date	Code	Title	Description
1995-08-07	B1	Patent granted (law 1993)
1999-03-29	PBP	Patent lapsed