DK232184A - Fremgangsmaade til fremstilling af 4-halogenmethylthiazoler og mellemprodukt til brug ved fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af 4-halogenmethylthiazoler og mellemprodukt til brug ved fremgangsmaaden Download PDF

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Publication number
DK232184A
DK232184A DK232184A DK232184A DK232184A DK 232184 A DK232184 A DK 232184A DK 232184 A DK232184 A DK 232184A DK 232184 A DK232184 A DK 232184A DK 232184 A DK232184 A DK 232184A
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DK
Denmark
Prior art keywords
procedure
halogenmethylthiazoles
intermediates
preparation
Prior art date
Application number
DK232184A
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English (en)
Other versions
DK161142B (da
DK161142C (da
DK232184D0 (da
Inventor
Gifford Purnell Marzoni
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK232184D0 publication Critical patent/DK232184D0/da
Publication of DK232184A publication Critical patent/DK232184A/da
Publication of DK161142B publication Critical patent/DK161142B/da
Application granted granted Critical
Publication of DK161142C publication Critical patent/DK161142C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK232184A 1983-05-12 1984-05-10 Fremgangsmaade til fremstilling af 4-halogenmethylthiazoler og mellemprodukt til brug ved fremgangsmaaden DK161142C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/493,883 US4468517A (en) 1983-05-12 1983-05-12 Synthesis of thiazoles
US49388383 1983-05-12

Publications (4)

Publication Number Publication Date
DK232184D0 DK232184D0 (da) 1984-05-10
DK232184A true DK232184A (da) 1984-11-13
DK161142B DK161142B (da) 1991-06-03
DK161142C DK161142C (da) 1991-11-18

Family

ID=23962095

Family Applications (1)

Application Number Title Priority Date Filing Date
DK232184A DK161142C (da) 1983-05-12 1984-05-10 Fremgangsmaade til fremstilling af 4-halogenmethylthiazoler og mellemprodukt til brug ved fremgangsmaaden

Country Status (12)

Country Link
US (1) US4468517A (da)
EP (1) EP0125887B1 (da)
JP (1) JPS59212482A (da)
KR (1) KR860001510B1 (da)
CA (1) CA1217486A (da)
DE (1) DE3461638D1 (da)
DK (1) DK161142C (da)
GB (1) GB2140802B (da)
GR (1) GR82074B (da)
HU (1) HU189111B (da)
IE (1) IE57395B1 (da)
IL (1) IL71786A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0960880A1 (en) * 1991-05-21 1999-12-01 Eli Lilly And Company Process for preparing intermediates to nizatidine and related compounds
US5541335A (en) * 1994-07-11 1996-07-30 Torcan Chemical Ltd. Process for preparing nizatidine
WO2002094798A1 (en) * 2001-05-23 2002-11-28 Nippon Soda Co.,Ltd. Process for preparation of thiazole compounds
AU2003245032A1 (en) * 2003-02-10 2004-08-30 Dinesh R. Kumar An improved process for preparing nizatidine intermediate
CN106279060A (zh) * 2016-08-10 2017-01-04 四川摩尔生物制药有限公司 尼扎替丁原料药的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3391151A (en) * 1966-05-23 1968-07-02 American Home Prod Benzhydrylthiazole derivatives
JPS5516145B2 (da) * 1971-10-18 1980-04-30
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
GB2140802A (en) 1984-12-05
IE57395B1 (en) 1992-08-26
GB8411887D0 (en) 1984-06-13
JPH0579672B2 (da) 1993-11-04
GR82074B (da) 1984-12-13
IL71786A (en) 1987-10-20
DE3461638D1 (en) 1987-01-22
KR840008800A (ko) 1984-12-19
HU189111B (en) 1986-06-30
IL71786A0 (en) 1984-09-30
HUT36104A (en) 1985-08-28
IE841161L (en) 1984-11-12
DK161142B (da) 1991-06-03
DK161142C (da) 1991-11-18
JPS59212482A (ja) 1984-12-01
CA1217486A (en) 1987-02-03
KR860001510B1 (ko) 1986-09-30
GB2140802B (en) 1986-10-15
EP0125887B1 (en) 1986-12-10
EP0125887A1 (en) 1984-11-21
US4468517A (en) 1984-08-28
DK232184D0 (da) 1984-05-10

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