DK237689A - PROCEDURE FOR PREPARING PYRIMIDINE DERIVATIVES - Google Patents

PROCEDURE FOR PREPARING PYRIMIDINE DERIVATIVES Download PDF

Info

Publication number
DK237689A
DK237689A DK237689A DK237689A DK237689A DK 237689 A DK237689 A DK 237689A DK 237689 A DK237689 A DK 237689A DK 237689 A DK237689 A DK 237689A DK 237689 A DK237689 A DK 237689A
Authority
DK
Denmark
Prior art keywords
procedure
pyrimidine derivatives
formula
image
preparing pyrimidine
Prior art date
Application number
DK237689A
Other languages
Danish (da)
Other versions
DK237689D0 (en
Inventor
Urs Hengartner
Gerard Moine
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK237689D0 publication Critical patent/DK237689D0/en
Publication of DK237689A publication Critical patent/DK237689A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D415/00—Heterocyclic compounds containing the thiamine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A process for the preparation of thiamine is described. This entails Grewe diamine being heated with an orthoformic ester, the resulting pyrimidine derivative of the formula <IMAGE> being reacted with a ketone of the formula <IMAGE> and the resulting compound of the formula <IMAGE> being converted into thiamine.
DK237689A 1988-05-17 1989-05-16 PROCEDURE FOR PREPARING PYRIMIDINE DERIVATIVES DK237689A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH185788 1988-05-17

Publications (2)

Publication Number Publication Date
DK237689D0 DK237689D0 (en) 1989-05-16
DK237689A true DK237689A (en) 1989-11-18

Family

ID=4220229

Family Applications (1)

Application Number Title Priority Date Filing Date
DK237689A DK237689A (en) 1988-05-17 1989-05-16 PROCEDURE FOR PREPARING PYRIMIDINE DERIVATIVES

Country Status (5)

Country Link
EP (1) EP0342482B1 (en)
JP (1) JP2755368B2 (en)
AT (1) ATE109479T1 (en)
DE (1) DE58908130D1 (en)
DK (1) DK237689A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105315272B (en) * 2015-10-19 2018-10-26 天津大学 A kind of preparation method of thiamine hydrochloride crystal product
CN114181203B (en) * 2021-12-24 2023-08-18 江苏兄弟维生素有限公司 Preparation method of thiamine hydrochloride, application and vitamin B1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4825198B1 (en) * 1969-08-20 1973-07-26

Also Published As

Publication number Publication date
ATE109479T1 (en) 1994-08-15
EP0342482A2 (en) 1989-11-23
JPH0217188A (en) 1990-01-22
EP0342482B1 (en) 1994-08-03
JP2755368B2 (en) 1998-05-20
DE58908130D1 (en) 1994-09-08
DK237689D0 (en) 1989-05-16
EP0342482A3 (en) 1990-11-28

Similar Documents

Publication Publication Date Title
DK0629609T3 (en) Process for the preparation of alkoxyiminoacetamide derivatives and an intermediate thereof
EP0742209A3 (en) A process for producing an optically active quinolinemevalonolactone and a process for producing an optically active quinolinemevalonic acid salt
AU518470B2 (en) 2-(2-alkoxyethyl)-2:-hydroxy-6,7-benzomorphanes
NO892626D0 (en) PROCEDURE FOR THE PREPARATION OF DIORGANODIAL COXYSILANES.
EP0291799A3 (en) Dioxyalkylenearyl-dihydropyridines and their intermediary compounds, process for their preparation and their use
DK150187A (en) PROCEDURE FOR THE PREPARATION OF HYDROXYAMINE DERIVATIVES
IE780145L (en) Meta-sulphonamido-benzamides
DK63388A (en) ISOCYANOMETHYL COMPOUND AND PROCEDURE FOR PREPARING AN OXADIAZOLIMIDAZOBENZODIAZEPINE DERIVATIVE
ES2086065T3 (en) PREPARATION OF SUBSTITUTED TETRAHIDROPIRIDINAS.
DK0565558T3 (en) Process and intermediates for the preparation of azabicyclo (2.2.2) octan-3-imines
DK0545511T3 (en) Process for the preparation of mono-N-substituted tetraazamacrocycles
DK237689D0 (en) PROCEDURE FOR PREPARING PYRIMIDINE DERIVATIVES
BR9105424A (en) PROCESS FOR PREPARING A PESTICIDE COMPOUND
DK0614908T3 (en) Process for the preparation of 3beta-aminocholanoic acid derivatives.
NO910911D0 (en) PROCEDURE FOR THE PREPARATION OF OXAZOLINE COMPOUNDS.
SE8701317L (en) PROCEDURE FOR PREPARING MORANOLINE DERIVATIVES
DK521785D0 (en) METHOD FOR PREPARING HALOGENERATED 3,3-DIMETHYL-5-HEXAN-2-ONER
AU2202892A (en) Ammonium salt of methyl 4,4,4-trifluoro-3-oxo-butanethioate
DK0538100T3 (en) Process for preparing derivatives of fluoroquinoline-3-carboxylic acid
DK464985A (en) PROCEDURE FOR THE MANUFACTURING OF OPTICAL ACTIVE RELATIONS
IL65663A (en) 5-aminomethyl-2,3-dihydro-2-oxo-1h-imidazole-4-carboxylic acid derivatives and process for their preparation
NO892410D0 (en) PROCEDURE FOR THE PREPARATION OF (+) 1 - ((3,4,5-TRIMETHOXY) -BENZYLOXYMETHYL) -1-PHENYL-N, N-DIMETHYL-N-PROPYLAMINE.
DK0533132T3 (en) Process for Oxidation of Hydroxymethylpyridine Derivatives to Pyridinecarboxylic Acid Derivatives
ES2074472T3 (en) PREPARATION PROCEDURE FOR A DERIVATIVE OF 1,4-DIHYDRO-PIRIDINE, LA (-) - 2 - ((2- (2-AMINO-ETOXI) -ETOXI) -METIL) -4- (2,3-DICHLORINE- PHENYL) -3-ETOXI-CARBONYL-5-METOXI-CARBONYL-6-METHYL-1,4-DIHYDRO-PIRIDINE AND ITS SALTS.
EP0080592B1 (en) A novel vasodilator compound, process for the preparation thereof and pharmaceutical compositions thereform

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment