DK2380587T3 - Anvendelse af en C1-inhibitor til forebyggelse af iskæmi-reperfusionsskade - Google Patents
Anvendelse af en C1-inhibitor til forebyggelse af iskæmi-reperfusionsskade Download PDFInfo
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- DK2380587T3 DK2380587T3 DK11172880.4T DK11172880T DK2380587T3 DK 2380587 T3 DK2380587 T3 DK 2380587T3 DK 11172880 T DK11172880 T DK 11172880T DK 2380587 T3 DK2380587 T3 DK 2380587T3
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- ischemia
- c1inh
- inhibitor
- inh
- ischemic
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Classifications
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
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Claims (4)
1. Anvendelse af en C1-inhibitor, der har et reduceret niveau af terminale sialinsyrerester sammenlignet med plasmaderiveret C1-inhibitor, hvor det reducerede niveau af terminale sialinsyrerester resulterer i en plasmahalveringstid på mindre end 6 timer, til fremstilling af en farmaceutisk sammensætning til forebyggelse, reduktion eller behandling af en iskæ-mi/reperfusionsskade, hvor C1-inhibitoren indgives højst 3 timer, 2 timer, 1 time eller 30 minutter før mindst én forudset forekomst af iskæmi og reperfu-sionsskade.
2. Anvendelse ifølge krav 1, hvor den forudsete forekomst af iskæmi og re-perfusionsskade er organtransplantation.
3. Anvendelse ifølge et hvilket som helst af kravene 1 eller 2, hvor C1-inhibitoren indgives kontinuerligt til et individ med behov herfor.
4. Anvendelse ifølge krav 1 eller 2, hvor C1-inhibitoren indgives til det organ, der skal transplanteres.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP05112630 | 2005-12-21 | ||
| US76094406P | 2006-01-23 | 2006-01-23 | |
| EP06824316A EP1965831B1 (en) | 2005-12-21 | 2006-12-19 | Use of c1 inhibitor for the prevention of ischemia-reperfusion injury |
Publications (1)
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|---|---|
| DK2380587T3 true DK2380587T3 (da) | 2017-12-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| DK11172880.4T DK2380587T3 (da) | 2005-12-21 | 2006-12-19 | Anvendelse af en C1-inhibitor til forebyggelse af iskæmi-reperfusionsskade |
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| EP (2) | EP1965831B1 (da) |
| JP (2) | JP5394748B2 (da) |
| KR (1) | KR101508668B1 (da) |
| AT (1) | ATE516043T1 (da) |
| AU (1) | AU2006327989B2 (da) |
| CA (1) | CA2632400C (da) |
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| HR (2) | HRP20110622T1 (da) |
| IL (2) | IL192180A (da) |
| NZ (1) | NZ568749A (da) |
| PL (2) | PL1965831T3 (da) |
| SI (1) | SI2380587T1 (da) |
| WO (1) | WO2007073186A2 (da) |
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| AU2003301332B2 (en) * | 2002-10-17 | 2008-06-12 | Pharming Intellectual Property B.V. | Protein modification |
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| CA2372128A1 (en) | 1999-05-14 | 2000-11-23 | Steffen Thiel | Novel indications of mannan-binding lectin (mbl) in the treatment of immunocompromised individuals |
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| DK1252184T3 (da) | 2000-01-31 | 2008-02-04 | Pharming Intellectual Pty Bv | Human C1-inhibitor produceret i mælk af transgene dyr |
| JP2004100982A (ja) * | 2002-09-05 | 2004-04-02 | Denso Corp | 熱交換器 |
| AU2003301332B2 (en) | 2002-10-17 | 2008-06-12 | Pharming Intellectual Property B.V. | Protein modification |
| PT1626736T (pt) | 2003-05-16 | 2020-10-13 | Pharming Intellectual Property B V | Inibidor c1 com curta meia-vida para tratamento transitório |
| SI2380587T1 (en) | 2005-12-21 | 2018-03-30 | Pharming Intellectual Property B.V. | Use of a C1 inhibitor to prevent ischemic reperfusion injury |
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