DK2388007T3 - Topisk præparat til anvendelse i behandlingen af rosacea-induceret rødme - Google Patents
Topisk præparat til anvendelse i behandlingen af rosacea-induceret rødme Download PDFInfo
- Publication number
- DK2388007T3 DK2388007T3 DK11175578.1T DK11175578T DK2388007T3 DK 2388007 T3 DK2388007 T3 DK 2388007T3 DK 11175578 T DK11175578 T DK 11175578T DK 2388007 T3 DK2388007 T3 DK 2388007T3
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- DK
- Denmark
- Prior art keywords
- pharmaceutically acceptable
- topical
- composition
- rosacea
- topical composition
- Prior art date
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Claims (12)
1. Anvendelse af et præparat, der omfatter: mindst den ene af en a2-adrenerg receptoragonist og et farmaceutisk acceptabelt salt deraf; og et farmaceutisk acceptabelt bæremateriale til fremstilling af et medikament til behandling af rosacea-induceret rødme, hvor præparatet er til topisk påføring direkte på det berørte hudområde hos en patient, der har behov for en sådan behandling, til reducering af blodstrømningen gennem de små arterier eller arterioler i patientens hud, og hvor præparatet virker lokalt i patientens hud, hvor den mindst ene af en a2-adrenerg receptoragonist og et farmaceutisk acceptabelt salt deraf er udvalgt fra forbindelsen, der vises nedenfor, og de farmaceutisk acceptable salte deraf:
2. Anvendelse ifølge krav 1, hvor det farmaceutisk acceptable bæremateriale er udvalgt fra gruppen, der består af sprayer, tåger, aerosoler, opløsninger, lotioner, geler, cremer, salver, pastaer, emulsioner og suspensioner.
3. Topisk præparat til anvendelse i behandlingen af rosacea-induceret rødme, hvilket topiske præparat omfatter: mindst den ene af en a2-adrenerg receptoragonist og et farmaceutisk acceptabelt salt deraf; og et farmaceutisk acceptabelt bæremateriale hvor præparatet er til topisk påføring direkte på det berørte hudområde hos en patient, der har behov for en sådan behandling, til reducering af blodstrømningen gennem de små arterier eller arterioler i patientens hud, og hvor præparatet virker lokalt i patientens hud, hvor den mindst ene af en a2-adrenerg receptoragonist og et farmaceutisk acceptabelt salt deraf er udvalgt fra forbindelsen, der vises nedenfor, og de farmaceutisk acceptable salte deraf:
4. Topisk præparat til anvendelse ifølge krav 3, hvor det farmaceutisk acceptable bæremateriale er udvalgt fra gruppen, der består af sprayer, tåger, aerosoler, opløsninger, lotioner, geler, cremer, salver, pastaer, emulsioner og suspensioner.
5. Topisk præparat til anvendelse ifølge krav 4, hvor det farmaceutisk acceptable bæremateriale er en vandig gel omfattende vand, og en vandgelerende mængde af et farmaceutisk acceptabelt geleringsmiddel udvalgt fra gruppen bestående af carbomerer, glycerinpolyacrylat og blandinger deraf, hvilket topisk præparat har et fysiologisk acceptabelt pH.
6. Topisk præparat til anvendelse ifølge krav 4, hvor det farmaceutisk acceptable bæremateriale er mindst én af en creme og en salve omfattende stearinsyre, stearylalkohol, cetylalkohol, glycerin og vand, hvilket topisk præparat har et fysiologisk acceptabelt pH.
7. Topisk præparat til anvendelse ifølge et hvilket som helst af kravene 3, 5 eller 6, hvor den mindst ene af en a2-adrenerg receptoragonist og et farmaceutisk acceptabelt salt deraf er til stede i en mængde i intervallet fra ca. 0,01 til 5 vægtprocent.
8. Topisk præparat til anvendelse ifølge et hvilket som helst af kravene 3, 5 eller 6, hvor pH-værdien for præparatet ligger i intervallet fra ca. 5 til 8.
9. Topisk præparat til anvendelse ifølge krav 5 eller 6, hvilket præparat yderligere omfatter et konserveringsmiddel.
10. Topisk præparat til anvendelse ifølge krav 5 eller 6, hvilket præparat yderligere omfatter et lokalanæstetikum.
11. Topisk præparat til anvendelse ifølge krav 5 eller 6, hvilket præparat yderligere omfatter et fugtighedsbevarende middel.
12. Topisk præparat til anvendelse ifølge krav 3, hvor præparatet er indbefattet i en emballage, hvilken emballage omfatter en beholder og anvisninger til brug af det topiske præparat til behandling af rosacea-induceret rødme.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47361103P | 2003-05-27 | 2003-05-27 | |
| US10/853,585 US7439241B2 (en) | 2003-05-27 | 2004-05-25 | Compounds, formulations, and methods for treating or preventing rosacea |
| EP04753601.6A EP1631293B2 (en) | 2003-05-27 | 2004-05-26 | Compounds, formulations, and methods for treating or preventing rosacea |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2388007T3 true DK2388007T3 (da) | 2015-09-28 |
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11175578.1T DK2388007T3 (da) | 2003-05-27 | 2004-05-26 | Topisk præparat til anvendelse i behandlingen af rosacea-induceret rødme |
| DK14179642.5T DK2815748T3 (da) | 2003-05-27 | 2004-05-26 | Forbindelser, formuleringer og fremgangsmåder til behandling eller forebyggelse af rosacea |
| DK04753601.6T DK1631293T4 (da) | 2003-05-27 | 2004-05-26 | Forbindelser, formuleringer og fremgangsmåder til behandling eller forebyggelse af rosacea |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14179642.5T DK2815748T3 (da) | 2003-05-27 | 2004-05-26 | Forbindelser, formuleringer og fremgangsmåder til behandling eller forebyggelse af rosacea |
| DK04753601.6T DK1631293T4 (da) | 2003-05-27 | 2004-05-26 | Forbindelser, formuleringer og fremgangsmåder til behandling eller forebyggelse af rosacea |
Country Status (22)
| Country | Link |
|---|---|
| US (13) | US7439241B2 (da) |
| EP (3) | EP1631293B2 (da) |
| CN (4) | CN1829518B (da) |
| AT (1) | ATE530185T1 (da) |
| AU (1) | AU2004242967C1 (da) |
| CA (1) | CA2530938C (da) |
| CY (3) | CY1112242T1 (da) |
| DK (3) | DK2388007T3 (da) |
| ES (3) | ES2376172T5 (da) |
| FR (1) | FR14C0056I2 (da) |
| HR (1) | HRP20150957T1 (da) |
| HU (3) | HUE027616T2 (da) |
| IL (1) | IL172612A (da) |
| LT (1) | LT2815748T (da) |
| LU (1) | LU92462I2 (da) |
| MX (1) | MXPA05014107A (da) |
| NO (1) | NO333468B1 (da) |
| NZ (1) | NZ544300A (da) |
| PL (3) | PL1631293T5 (da) |
| PT (3) | PT1631293E (da) |
| SI (3) | SI2815748T1 (da) |
| WO (1) | WO2004105703A2 (da) |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040266776A1 (en) * | 2003-06-25 | 2004-12-30 | Gil Daniel W. | Methods of preventing and reducing the severity of stress-associated conditions |
| US8410102B2 (en) * | 2003-05-27 | 2013-04-02 | Galderma Laboratories Inc. | Methods and compositions for treating or preventing erythema |
| US7439241B2 (en) | 2003-05-27 | 2008-10-21 | Galderma Laboratories, Inc. | Compounds, formulations, and methods for treating or preventing rosacea |
| US20050020600A1 (en) * | 2003-07-23 | 2005-01-27 | Scherer Warren J. | Methods of treating cutaneous flushing using selective alpha-2-adrenergic receptor agonists |
| US7812049B2 (en) * | 2004-01-22 | 2010-10-12 | Vicept Therapeutics, Inc. | Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using α1-adrenoceptor agonists |
| PT1761266E (pt) * | 2004-05-25 | 2013-06-04 | Galderma Pharma Sa | Compostos, formulações, e métodos para tratamento ou prevenção de distúrbios inflamatórios da pele |
| US20080095735A1 (en) * | 2005-01-31 | 2008-04-24 | Kross Robert D | Skin-Protective Polymer For Use In Teat Care Compositions |
| DE202005002183U1 (de) | 2005-02-04 | 2005-04-14 | Beiersdorf Ag | Hautverwöhnende Cremelotion |
| JP5388568B2 (ja) * | 2005-03-30 | 2014-01-15 | ルバンス セラピュティックス インク． | ざ瘡を治療するための組成物及び方法 |
| PL1890732T3 (pl) | 2005-06-17 | 2018-11-30 | Wisconsin Alumni Research Foundation | Preparaty zwężające naczynia krwionośne do podawania miejscowego i sposoby ochrony komórek podczas chemioterapii i radioterapii przeciwnowotworowej |
| WO2007002447A2 (en) * | 2005-06-23 | 2007-01-04 | Bioform Medical, Inc. | Compositions for treating rosacea |
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