DK2490708T3 - Stabiliserede glucagon-opløsninger - Google Patents

Stabiliserede glucagon-opløsninger

Info

Publication number: DK2490708T3
Authority: DK; Denmark
Prior art keywords: glucagon solutions; stabilized glucagon; stabilized; solutions; glucagon
Prior art date: 2009-10-22

Application number

DK10763107.9T

Other languages

English (en)

Inventor

Solomon S Steiner

Robert Hauser

Ming Li

Robert Feldstein

Roderike Pohl

Original Assignee

Biodel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-10-22

Filing date

2010-09-27

Publication date

2013-04-15

2010-03-01 Priority claimed from US12/715,203 external-priority patent/US20110097386A1/en

2010-09-27 Application filed by Biodel Inc filed Critical Biodel Inc

2013-04-15 Application granted granted Critical

2013-04-15 Publication of DK2490708T3 publication Critical patent/DK2490708T3/da

Links

102000051325 Glucagon Human genes 0.000 title 1
108060003199 Glucagon Proteins 0.000 title 1
MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 title 1
229960004666 glucagon Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Zoology (AREA)
Dispersion Chemistry (AREA)
Endocrinology (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dermatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

DK10763107.9T 2009-10-22 2010-09-27 Stabiliserede glucagon-opløsninger DK2490708T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US25412809P	2009-10-22	2009-10-22
US12/715,203 US20110097386A1 (en)	2009-10-22	2010-03-01	Stabilized glucagon solutions
US32744010P	2010-04-23	2010-04-23
PCT/US2010/050386 WO2011049713A2 (en)	2009-10-22	2010-09-27	Stabilized glucagon solutions

Publications (1)

Publication Number	Publication Date
DK2490708T3 true DK2490708T3 (da)	2013-04-15

Family

ID=43900885

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK10763107.9T DK2490708T3 (da)	2009-10-22	2010-09-27	Stabiliserede glucagon-opløsninger

Country Status (3)

Country	Link
EP (1)	EP2490708B1 (da)
DK (1)	DK2490708T3 (da)
WO (1)	WO2011049713A2 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5894174B2 (ja)	2010-11-03	2016-03-23	アレコーリミテッド	グルカゴンを含む新規組成物
UA116217C2 (uk)	2012-10-09	2018-02-26	Санофі	Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
SG10201705097PA (en)	2012-12-21	2017-07-28	Sanofi Sa	Functionalized exendin-4 derivatives
WO2015086730A1 (en)	2013-12-13	2015-06-18	Sanofi	Non-acylated exendin-4 peptide analogues
EP3080149A1 (en)	2013-12-13	2016-10-19	Sanofi	Dual glp-1/glucagon receptor agonists
TW201609795A (zh)	2013-12-13	2016-03-16	賽諾菲公司	作為雙重ｇｌｐ－１／ｇｉｐ受體促效劑的艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物
WO2015086729A1 (en)	2013-12-13	2015-06-18	Sanofi	Dual glp-1/gip receptor agonists
TW201625668A (zh)	2014-04-07	2016-07-16	賽諾菲公司	作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物
TW201625669A (zh)	2014-04-07	2016-07-16	賽諾菲公司	衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
TW201625670A (zh)	2014-04-07	2016-07-16	賽諾菲公司	衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑
US9932381B2 (en)	2014-06-18	2018-04-03	Sanofi	Exendin-4 derivatives as selective glucagon receptor agonists
AR105319A1 (es)	2015-06-05	2017-09-27	Sanofi Sa	Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
AR105284A1 (es)	2015-07-10	2017-09-20	Sanofi Sa	Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
CN114028655A (zh)	2015-08-24	2022-02-11	阿达米制药公司	注射器装置
GB201611077D0 (en)	2016-06-24	2016-08-10	Arecor Ltd	Novel composition
US11027072B2 (en)	2018-05-25	2021-06-08	Adamis Pharmaceuticals Corporation	Emergency devices
KR20210013617A (ko)	2018-05-25	2021-02-04	아다미스 파마슈티칼스 코포레이션	응급 장치

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1202607A (en)	1968-01-10	1970-08-19	Novo Terapeutisk Labor As	Improvements in or relating to stable glucagon solutions and their preparation
US5652216A (en)	1994-05-26	1997-07-29	Novo Nordisk A/S	Pharmaceutical preparation
AU2612599A (en)	1998-03-13	1999-10-11	Novo Nordisk A/S	Stabilized aqueous peptide solutions
GB9930882D0 (en) *	1999-12-30	2000-02-23	Nps Allelix Corp	GLP-2 formulations
CN1812808B (zh) *	2003-06-03	2012-07-04	诺沃挪第克公司	稳定化的药物肽组合物

2010
- 2010-09-27 WO PCT/US2010/050386 patent/WO2011049713A2/en not_active Ceased
- 2010-09-27 DK DK10763107.9T patent/DK2490708T3/da active
- 2010-09-27 EP EP10763107A patent/EP2490708B1/en not_active Not-in-force

Also Published As

Publication number	Publication date
WO2011049713A2 (en)	2011-04-28
EP2490708B1 (en)	2013-03-27
WO2011049713A3 (en)	2011-12-01
EP2490708A2 (en)	2012-08-29

Publication	Publication Date	Title
DK2490708T3 (da)	2013-04-15	Stabiliserede glucagon-opløsninger
NO2017031I1 (no)	2017-07-06	insulin aspart
DK2370461T3 (da)	2013-12-16	Glucagonanaloger
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DE112010004215A5 (de)	2012-08-23	Hydrostataktor
DE112010002949A5 (de)	2012-09-06	Kupplungstastpunkte
EP2469625A4 (en)	2015-11-04	OMNIBUS BAR
EP2445547A4 (en)	2012-12-12	CATHETERISM SYSTEM
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DK2430035T3 (da)	2013-05-27	Uracylspipooxetannukleosider
BRPI1008827A2 (pt)	2016-02-23	deisobutenizador
BRPI1014968A2 (pt)	2016-12-13	subalargador
DE112010002728A5 (de)	2012-06-21	Turboinhalator
DE112010004249A5 (de)	2012-11-29	Spindelaktor
EP2446176A4 (en)	2016-12-14	CYLINDER SEAL
DE112009005323A5 (de)	2012-07-26	Hebelarmprüfmaschine
DE112009005462T8 (de)	2013-03-28	Lenkungsssteuervorrichtung
BRPI1008070A2 (pt)	2016-03-15	tricianoboratos
BR112012004964A2 (pt)	2016-04-05	girocóptero
EP2409976A4 (en)	2012-09-19	GLYCINE TRANSPORTER INHIBITOR
EP2508411A4 (en)	2013-05-08	STRUCTURE
DK2483126T3 (da)	2015-06-22	Skinnekøretøj