DK255190A - Visse paf-antagonist/antihistamin-kombinationer og fremgangsmaader - Google Patents

Visse paf-antagonist/antihistamin-kombinationer og fremgangsmaader Download PDF

Info

Publication number: DK255190A
Authority: DK; Denmark
Prior art keywords: certain; procedures; paf antagonist; combinations; antihistamine
Prior art date: 1988-04-27

Application number

DK255190A

Other languages

English (en)

Other versions

DK255190D0 (da

Inventor

M Motasim Billah

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-27

Filing date

1990-10-23

Publication date

1990-10-23

1990-10-23 Application filed by Schering Corp filed Critical Schering Corp

1990-10-23 Publication of DK255190D0 publication Critical patent/DK255190D0/da

1990-10-23 Publication of DK255190A publication Critical patent/DK255190A/da

Links

238000000034 method Methods 0.000 title abstract 2
239000003848 thrombocyte activating factor antagonist Substances 0.000 title abstract 2
GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title 1
230000001387 anti-histamine Effects 0.000 title 1
239000000739 antihistaminic agent Substances 0.000 title 1
-1 diaryl tetrahydrofuran Chemical compound 0.000 abstract 2
206010020751 Hypersensitivity Diseases 0.000 abstract 1
229940066051 combinations of antihistamines Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
WYURNTSHIVDZCO-UHFFFAOYSA-N tetrahydrofuran Substances C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 1
KYTREVLPRJOBEM-UHFFFAOYSA-N triazolo[4,5-i][1,2]benzodiazepine Chemical compound C1=CC2=CC=CN=NC2=C2C1=NN=N2 KYTREVLPRJOBEM-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK255190A 1988-04-27 1990-10-23 Visse paf-antagonist/antihistamin-kombinationer og fremgangsmaader DK255190A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US18653588A	1988-04-27	1988-04-27
PCT/US1989/001671 WO1989010143A1 (en)	1988-04-27	1989-04-24	Certain paf antagonist antihistamine combinations and methods

Publications (2)

Publication Number	Publication Date
DK255190D0 DK255190D0 (da)	1990-10-23
DK255190A true DK255190A (da)	1990-10-23

Family

ID=22685331

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK255190A DK255190A (da)	1988-04-27	1990-10-23	Visse paf-antagonist/antihistamin-kombinationer og fremgangsmaader

Country Status (15)

Country	Link
EP (2)	EP0345931B1 (da)
JP (1)	JPH0655673B2 (da)
KR (1)	KR930009786B1 (da)
AT (1)	ATE84724T1 (da)
AU (1)	AU619555B2 (da)
CA (1)	CA1327316C (da)
DE (1)	DE68904475T2 (da)
DK (1)	DK255190A (da)
ES (1)	ES2044100T4 (da)
IE (1)	IE63697B1 (da)
IL (1)	IL90100A (da)
MY (1)	MY106956A (da)
NZ (1)	NZ228879A (da)
WO (1)	WO1989010143A1 (da)
ZA (1)	ZA893101B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH30676A (en) *	1986-07-22	1997-09-16	Boehringer Ingelhein Kg	Hetrazepine compounds which have useful pharmaceutical utility
US6277846B1 (en) *	1990-05-31	2001-08-21	Allergan Sales, Inc.	Use of platelet activating factor antagonists as anti-pruritic agents
US5227378A (en) *	1990-08-02	1993-07-13	Hoffmann-La Roche Inc.	Combination of PAF antagonists and LTD4 antagonists for the treatment of allergic reactions
EP0469477B1 (en) *	1990-08-02	1995-09-20	F. Hoffmann-La Roche Ag	Antiallergic combination
FR2673842B1 (fr) *	1991-03-13	1993-12-24	Rhone Poulenc Rorer Sa	Nouvelles compositions liquides a base de derives de la piperidine substitues en 1,4.
FR2684298B1 (fr) *	1991-12-03	1994-03-11	Rhone Poulenc Rorer Sa	Nouvelles compositions pharmaceutiques solides a base de derives de lapiperidine substitues en 1,4.
JP3060287B2 (ja) *	1995-10-09	2000-07-10	参天製薬株式会社	アパファントを主薬とする水性点眼剤
DE10007203A1 (de) *	2000-02-17	2001-08-23	Asta Medica Ag	Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US8492376B2 (en) *	2010-04-21	2013-07-23	Hoffmann-La Roche Inc.	Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4539332A (en) *	1983-11-14	1985-09-03	Merck & Co., Inc.	2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists
NZ211146A (en) *	1984-02-29	1987-10-30	Merck & Co Inc	2,5-diaryl-tetrahydrothiophene derivatives and pharmaceutical compositions
US4595693A (en) *	1984-06-04	1986-06-17	Merck & Co., Inc.	Method of use of 2,5-diaryl tetrahydrofurans and analogs thereof as PAF-antagonists
DE3502392A1 (de) *	1985-01-25	1986-07-31	Boehringer Ingelheim KG, 6507 Ingelheim	Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
US4910206A (en) *	1986-07-14	1990-03-20	Sandoz Pharmaceuticals Corp.	5-hetero-or aryl-substituted-imidazo(2,1-a)isoquinolines and their use as PAF receptor antagonists

1989
- 1989-04-24 EP EP89304068A patent/EP0345931B1/en not_active Expired - Lifetime
- 1989-04-24 DE DE8989304068T patent/DE68904475T2/de not_active Expired - Fee Related
- 1989-04-24 AT AT89304068T patent/ATE84724T1/de not_active IP Right Cessation
- 1989-04-24 ES ES89304068T patent/ES2044100T4/es not_active Expired - Lifetime
- 1989-04-24 AU AU35782/89A patent/AU619555B2/en not_active Ceased
- 1989-04-24 EP EP89905952A patent/EP0402422A1/en active Pending
- 1989-04-24 KR KR1019890702438A patent/KR930009786B1/ko not_active Expired - Fee Related
- 1989-04-24 JP JP1505865A patent/JPH0655673B2/ja not_active Expired - Lifetime
- 1989-04-24 WO PCT/US1989/001671 patent/WO1989010143A1/en not_active Ceased
- 1989-04-26 NZ NZ228879A patent/NZ228879A/en unknown
- 1989-04-26 IE IE136289A patent/IE63697B1/en not_active IP Right Cessation
- 1989-04-26 MY MYPI89000538A patent/MY106956A/en unknown
- 1989-04-26 ZA ZA893101A patent/ZA893101B/xx unknown
- 1989-04-26 CA CA000597855A patent/CA1327316C/en not_active Expired - Fee Related
- 1989-04-27 IL IL9010089A patent/IL90100A/en not_active IP Right Cessation
1990
- 1990-10-23 DK DK255190A patent/DK255190A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
NZ228879A (en)	1992-08-26
AU3578289A (en)	1989-11-24
MY106956A (en)	1995-08-30
EP0345931A1 (en)	1989-12-13
ATE84724T1 (de)	1993-02-15
ZA893101B (en)	1989-12-27
IE891362L (en)	1989-10-27
ES2044100T4 (es)	1996-07-16
DE68904475D1 (de)	1993-03-04
EP0402422A1 (en)	1990-12-19
EP0345931B1 (en)	1993-01-20
JPH0655673B2 (ja)	1994-07-27
CA1327316C (en)	1994-03-01
DK255190D0 (da)	1990-10-23
IL90100A0 (en)	1989-12-15
IE63697B1 (en)	1995-05-31
DE68904475T2 (de)	1993-05-13
WO1989010143A1 (en)	1989-11-02
ES2044100T3 (es)	1994-01-01
JPH03502097A (ja)	1991-05-16
KR900700136A (ko)	1990-08-11
KR930009786B1 (ko)	1993-10-11
AU619555B2 (en)	1992-01-30
IL90100A (en)	1995-01-24

Legal Events

Date	Code	Title	Description
2000-12-04	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DE3885816D1 (de)	1994-01-05	Mischungen von Polycarbonat und von Siloxan-Polyetherimid-Copolymer.
FI882791A7 (fi)	1988-12-13	Aineita, jotka parantavat määrättyjen 1,4-dihydropyridiinijohdannaisten siirtymistä ihon läpi.
ES8602768A1 (es)	1985-11-16	Un procedimiento para la preparacion de nuevas n-(heterociclil biciclo)-4-piperidinaminas.
DE3889091D1 (de)	1994-05-19	Härtbare Zusammensetzung von Oxyalkylenpolymeren.
DE69402330D1 (de)	1997-04-30	Analgetisches mittel und dessen verwendung
DE3853340D1 (de)	1995-04-20	Dien-Blockpolymer und Polymerzusammensetzung.
FI915970A7 (fi)	1991-12-18	Lääkkeitä, jotka ovat hyödyllisiä syövän hoidossa ja joilla on antihis tamiiniominaisuuksia
DE3866038D1 (de)	1991-12-12	Bohrer und zugehoeriger schneideinsatz.
DK255190A (da)	1990-10-23	Visse paf-antagonist/antihistamin-kombinationer og fremgangsmaader
DE68906345D1 (de)	1993-06-09	Antimalariazusammenstellungen, gebrauchmachend von quinidin, artemisinin und ihren derivaten.
DE3887345D1 (de)	1994-03-03	Fluoriertes copolymer und sperrschichten.
DK0669394T3 (da)	2000-05-29	Bifunktionelle urokinasevarianter med forbedrede fibrinolytiske egenskaber og thrombinhæmmende virkninger
NO893892D0 (no)	1989-09-29	Antimikrobiologisk sammensetning og fremgangsmaate for anvendelse.
DE68914711D1 (de)	1994-05-26	1,4-Disubstituierte-2,3,4,6-tetrahydroxy-1,4-diphosphorinan und ihre Oxide oder Sulfides.
NO894532D0 (no)	1989-11-14	Titandioksyd, fremgangsmaate for dets fremstilling og anvendelse derav.
DE3576689D1 (de)	1990-04-26	Oxa- und thiadiazolylderivate und ihre verwendung.
FI883943A0 (fi)	1988-08-26	Modifierade plasminogen-aktivatorer.
NO881965D0 (no)	1988-05-05	Tilsetningsmiddel for borevaesker, fremstilling og anvendelse.
DK0458537T3 (da)	1999-10-18	Anvendelse af en terapeutisk forbindelse til behandling af bronkitis
DE68919593D1 (de)	1995-01-12	Verwendung von Zofenopril zur Herstellung von Medikamenten gegen rheumatoide Arthritis.
FI896159A0 (fi)	1989-12-21	Valsanordning med en undervals med hydrauliskt innerstoed.
DK24889D0 (da)	1989-01-20	Tetrahydropyridin-derivater
FI883268A0 (fi)	1988-07-08	Engaongssugpaose foer patientsekret.
FR2654242B1 (fr)	1994-05-20	Jeu educatif.
ATE88893T1 (de)	1993-05-15	Antimalariazusammenstellungen, gebrauchmachend von quinidin, artemisinin und ihren derivaten.