DK2571507T3 - Formuleringer og fremgangsmåder til behandling af hudtilstande - Google Patents
Formuleringer og fremgangsmåder til behandling af hudtilstande Download PDFInfo
- Publication number
- DK2571507T3 DK2571507T3 DK11777830.8T DK11777830T DK2571507T3 DK 2571507 T3 DK2571507 T3 DK 2571507T3 DK 11777830 T DK11777830 T DK 11777830T DK 2571507 T3 DK2571507 T3 DK 2571507T3
- Authority
- DK
- Denmark
- Prior art keywords
- hypericin
- psoriasis
- treatment
- light
- skin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (3)
1. Flydende formulering til anvendelse inden for topisk behandling af psoriasis, omfattende: en fotosensibilisator i en mængde på 0,001 % til 1 %, hvor fotosensibilisato-ren udviser cytotoksicitet, når den udsættes for lys i det synlige spektrum, og fotosensibilisatoren er hypericin eller et hypericin-derivat; og et organisk opløsningsmiddel i en mængde på 25 % til 75 %, hvor det organiske opøsningsmiddel øger hudgennemtrængeligheden, og det organiske opløsningsmiddel er dimethylsulfoxid.
2. Flydende formulering af en fotosensibilisator ifølge krav 1 til anvendelse inden for behandling af psoriasis, hvilken omfatter de følgende trin: At påføre den flydende formulering topisk på en hudlæsion af en patient, der lider af psoriasis; og at udsætte hudlæsionen for en lyskilde.
3. Flydende formulering til anvendelse ifølge krav 2, hvor lyskilden er en synlig lyskilde, som udsender lys med en bølgelængde på mellem 500 nm og 650 nm, en bølgelængde på mellem 390 nm og 750 nm, en bølgelængde på mellem 380 nm og 750 nm, en bølgelængde på mellem 495 nm og 570 nm, en bølgelængde på mellem 450 nm og 495 nm, en bølgelængde på mellem 570 nm og 590 nm, en bølgelængde på mellem 590 nm og 620 nm, eller en bølgelængde på mellem 620 nm og 750 nm.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33113110P | 2010-05-04 | 2010-05-04 | |
| PCT/US2011/033161 WO2011139558A1 (en) | 2010-05-04 | 2011-04-20 | Formulations and methods of treatment of skin conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2571507T3 true DK2571507T3 (da) | 2017-04-03 |
Family
ID=44903962
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11777830.8T DK2571507T3 (da) | 2010-05-04 | 2011-04-20 | Formuleringer og fremgangsmåder til behandling af hudtilstande |
| DK15167184.9T DK2932973T3 (da) | 2010-05-04 | 2011-04-20 | Formuleringer til anvendelse til behandling af hudtilstande |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15167184.9T DK2932973T3 (da) | 2010-05-04 | 2011-04-20 | Formuleringer til anvendelse til behandling af hudtilstande |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20130211371A1 (da) |
| EP (2) | EP2571507B1 (da) |
| DK (2) | DK2571507T3 (da) |
| ES (2) | ES2619612T3 (da) |
| WO (1) | WO2011139558A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10053413B2 (en) | 2016-03-01 | 2018-08-21 | Soligenix, Inc. | Systems and methods for producing synthetic hypericin |
| JP2024524602A (ja) * | 2021-07-08 | 2024-07-05 | ソリジェニックス インコーポレーテッド | 皮膚科学的組成物および皮膚ｔ細胞リンパ腫に対する治療方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001882A (en) | 1997-07-03 | 1999-12-14 | The Trustees Of The University Of Pennsylvania | Photoactivated hypericin and the use thereof |
| IL121440A0 (en) | 1997-07-31 | 1998-01-04 | Yeda Res & Dev | The use of 1,3,4,6-tetrahydroxy-helianthrone and its derivatives in photodynamic therapy and certain such novel derivatives |
| WO2001056558A1 (en) | 2000-01-31 | 2001-08-09 | Yeda Research And Development Co. Ltd. | Polycyclic dianthraquinones as anti-cancer and anti-angiogenic agents |
| WO2009066294A1 (en) * | 2007-11-20 | 2009-05-28 | Hy Biopharma Inc. | Device and method for photodynamic therapy |
-
2011
- 2011-04-20 DK DK11777830.8T patent/DK2571507T3/da active
- 2011-04-20 ES ES11777830.8T patent/ES2619612T3/es active Active
- 2011-04-20 EP EP11777830.8A patent/EP2571507B1/en active Active
- 2011-04-20 ES ES15167184T patent/ES2791762T3/es active Active
- 2011-04-20 US US13/695,902 patent/US20130211371A1/en not_active Abandoned
- 2011-04-20 EP EP15167184.9A patent/EP2932973B1/en active Active
- 2011-04-20 WO PCT/US2011/033161 patent/WO2011139558A1/en not_active Ceased
- 2011-04-20 DK DK15167184.9T patent/DK2932973T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2932973B1 (en) | 2020-04-01 |
| EP2571507A1 (en) | 2013-03-27 |
| EP2571507B1 (en) | 2017-01-04 |
| HK1214771A1 (en) | 2016-08-05 |
| DK2932973T3 (da) | 2020-06-02 |
| ES2619612T3 (es) | 2017-06-26 |
| US20130211371A1 (en) | 2013-08-15 |
| EP2571507A4 (en) | 2013-11-06 |
| EP2932973A1 (en) | 2015-10-21 |
| WO2011139558A1 (en) | 2011-11-10 |
| ES2791762T3 (es) | 2020-11-05 |
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