DK26180A - Fremgangsmaade til fremstilling af diterpenderivater - Google Patents

Fremgangsmaade til fremstilling af diterpenderivater

Info

Publication number: DK26180A
Authority: DK; Denmark
Prior art keywords: diter; pendant; derivatives; procedure; preparation
Prior art date: 1979-01-23

Application number

DK26180A

Other languages

English (en)

Inventor

E Hecker

H Osswald

R Schmidt

H J Opferkuch

B Sorg

W Adolf

Original Assignee

Deutsches Krebsforsch

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-01-23

Filing date

1980-01-22

Publication date

1980-07-24

1980-01-22 Application filed by Deutsches Krebsforsch filed Critical Deutsches Krebsforsch

1980-07-24 Publication of DK26180A publication Critical patent/DK26180A/da

Links

238000000034 method Methods 0.000 title abstract 2
238000005392 polarisation enhancment during attached nucleus testing Methods 0.000 title 1
QGVLYPPODPLXMB-UBTYZVCOSA-N (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-5H-cyclopropa[3,4]benzo[1,2-e]azulen-5-one Chemical compound C1=C(CO)C[C@]2(O)C(=O)C(C)=C[C@H]2[C@@]2(O)[C@H](C)[C@@H](O)[C@@]3(O)C(C)(C)[C@H]3[C@@H]21 QGVLYPPODPLXMB-UBTYZVCOSA-N 0.000 abstract 1
230000005907 cancer growth Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
QGVLYPPODPLXMB-QXYKVGAMSA-N phorbol Natural products C[C@@H]1[C@@H](O)[C@]2(O)[C@H]([C@H]3C=C(CO)C[C@@]4(O)[C@H](C=C(C)C4=O)[C@@]13O)C2(C)C QGVLYPPODPLXMB-QXYKVGAMSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
- C07C49/727—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)
Treatments Of Macromolecular Shaped Articles (AREA)

DK26180A 1979-01-23 1980-01-22 Fremgangsmaade til fremstilling af diterpenderivater DK26180A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19792902506 DE2902506A1 (de)	1979-01-23	1979-01-23	Verwendung von nicht oder nur gering irritierenden und/oder promovierenden diterpenalkoholen und von derivaten davon als antineoplastische mittel

Publications (1)

Publication Number	Publication Date
DK26180A true DK26180A (da)	1980-07-24

Family

ID=6061217

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK26180A DK26180A (da)	1979-01-23	1980-01-22	Fremgangsmaade til fremstilling af diterpenderivater

Country Status (15)

Country	Link
US (1)	US4716179A (da)
EP (1)	EP0013983B1 (da)
JP (1)	JPS55136221A (da)
AT (1)	ATE8203T1 (da)
AU (1)	AU529955B2 (da)
CA (1)	CA1160953A (da)
DD (1)	DD150430A5 (da)
DE (1)	DE2902506A1 (da)
DK (1)	DK26180A (da)
FI (1)	FI800171A7 (da)
IE (1)	IE50419B1 (da)
MC (1)	MC1298A1 (da)
NO (1)	NO800148L (da)
YU (1)	YU17880A (da)
ZA (1)	ZA80403B (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6043270A (en) *	1986-06-11	2000-03-28	Procyon Pharmaceuticals, Inc.	Protein kinase C modulators V
US5716968A (en) *	1986-06-11	1998-02-10	Procyon Pharmaceuticals, Inc.	Protein kinase C modulators. H.
US5891870A (en) *	1986-06-11	1999-04-06	Procyon Pharmaceuticals, Inc.	Protein kinase C modulators Q
US5955501A (en) *	1986-06-11	1999-09-21	Procyon Pharmaceuticals, Inc.	Protein kinase C modulators O
US5750568A (en) *	1986-06-11	1998-05-12	Procyon Pharmaceuticals, Inc.	Protein kinase C Modulators. L.
US5962498A (en) *	1986-06-11	1999-10-05	Procyon Pharmaceuticals, Inc.	Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity
US5886019A (en) *	1986-06-11	1999-03-23	Procyon Pharmaceuticals, Inc.	Protein kinase C modulators. F.
US6080784A (en) *	1986-06-11	2000-06-27	Procyon Pharmaceuticals, Inc.	Protein kinase C modulators N
US5891906A (en) *	1986-06-11	1999-04-06	Procyon Pharmaceuticals, Inc.	Polyacetate-derived phorboids having anti-inflammatory and other uses
US4818359A (en) *	1986-08-27	1989-04-04	International Business Machines Corporation	Low contamination RF sputter deposition apparatus
US4939149A (en) *	1988-10-24	1990-07-03	The United States Of America As Represented By The Department Of Health And Human Services	Resiniferatoxin and analogues thereof to cause sensory afferent C-fiber and thermoregulatory desensitization
US5021450A (en) *	1989-05-30	1991-06-04	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	New class of compounds having a variable spectrum of activities for capsaicin-like responses, compositions and uses thereof
DE4005159A1 (de) *	1990-02-17	1991-08-22	Merck Patent Gmbh	Diterpene mit immunmodulatorischer wirkung
WO1992017064A2 (en) *	1991-04-08	1992-10-15	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Inhibitors of protein kinase c function
US5405875A (en) *	1991-04-08	1995-04-11	The United States Of America As Represented By The Department Of Health And Human Services	Method of inhibiting neoplasia and tumor promotion
AUPO864097A0 (en)	1997-08-19	1997-09-11	Peplin Pty Ltd	Anti-cancer compounds
KR100336982B1 (ko) *	1998-12-31	2002-05-17	성재갑	피부 미백용 조성물
AUPQ801700A0 (en) *	2000-06-07	2000-06-29	Peplin Research Pty Ltd	Enzyme and viral activation
AUPQ923100A0 (en)	2000-08-07	2000-08-31	Peplin Research Pty Ltd	Treatment of prostate cancer
GB0126000D0 (en) *	2001-10-30	2001-12-19	Univ Dundee	Use of 4ñ Phorbol
DE10233737A1 (de) *	2002-07-24	2004-02-05	Morphochem Aktiengesellschaft für kombinatorische Chemie	Verwendung von Modulatoren des Signaltransduktionswegs über die Proteinkinase Fyn zur Behandlung von Tumorerkrankungen
US7208183B2 (en) *	2002-10-05	2007-04-24	Bobrowski Paul J	Methods and preparations of the latex from the croton species
EP1838330A4 (en)	2004-12-13	2010-07-07	Peplin Research Pty Ltd	TREATMENT OF SOLID TUMORS
KR20080077625A (ko) *	2005-11-25	2008-08-25	페플린 리서치 피티이 리미티드	상처 치유 방법
JP2014507396A (ja) *	2010-12-22	2014-03-27	レオ・ラボラトリーズ・リミテッド	イノゲノール−３−アシラートｉ
CN103402969A (zh) *	2010-12-22	2013-11-20	利奥实验室有限公司	3-酰基-巨大戟二萜醇ii
CA2875461A1 (en) *	2012-06-26	2014-01-03	Xifu Liang	3-o-heteroaryl-ingenol
US12502369B2 (en)	2015-11-11	2025-12-23	K-Gen, Inc.	Methods of cancer treatment
CN107164421B (zh) *	2016-03-08	2021-01-26	复旦大学	羟基化续随子二萜烷型衍生物的转化方法及其在制备抗肿瘤药物中的用途
CN107164422B (zh) *	2016-03-08	2021-01-22	复旦大学	续随子二萜醇衍生物的转化方法及其在制备抗肿瘤药物中的用途
US10722484B2 (en)	2016-03-09	2020-07-28	K-Gen, Inc.	Methods of cancer treatment

1979
- 1979-01-23 DE DE19792902506 patent/DE2902506A1/de not_active Withdrawn
1980
- 1980-01-22 FI FI800171A patent/FI800171A7/fi not_active Application Discontinuation
- 1980-01-22 DK DK26180A patent/DK26180A/da not_active Application Discontinuation
- 1980-01-22 DD DD80218582A patent/DD150430A5/de unknown
- 1980-01-22 NO NO800148A patent/NO800148L/no unknown
- 1980-01-22 CA CA000344178A patent/CA1160953A/en not_active Expired
- 1980-01-23 JP JP672980A patent/JPS55136221A/ja active Pending
- 1980-01-23 AT AT80100353T patent/ATE8203T1/de not_active IP Right Cessation
- 1980-01-23 ZA ZA00800403A patent/ZA80403B/xx unknown
- 1980-01-23 EP EP80100353A patent/EP0013983B1/de not_active Expired
- 1980-01-23 IE IE132/80A patent/IE50419B1/en unknown
- 1980-01-23 AU AU54860/80A patent/AU529955B2/en not_active Ceased
- 1980-01-23 MC MC801423A patent/MC1298A1/fr unknown
- 1980-01-23 YU YU00178/80A patent/YU17880A/xx unknown
1984
- 1984-02-29 US US06/584,738 patent/US4716179A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0013983A2 (de)	1980-08-06
IE800132L (en)	1980-07-23
IE50419B1 (en)	1986-04-16
JPS55136221A (en)	1980-10-23
AU529955B2 (en)	1983-06-30
AU5486080A (en)	1980-07-31
US4716179A (en)	1987-12-29
ZA80403B (en)	1981-01-28
EP0013983A3 (en)	1981-03-25
CA1160953A (en)	1984-01-24
ATE8203T1 (de)	1984-07-15
NO800148L (no)	1980-07-24
YU17880A (en)	1983-01-21
DD150430A5 (de)	1981-09-02
FI800171A7 (fi)	1981-01-01
MC1298A1 (fr)	1980-10-03
DE2902506A1 (de)	1980-07-24
EP0013983B1 (de)	1984-07-04

Legal Events

Date	Code	Title	Description
1986-10-27	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK26180A (da)	1980-07-24	Fremgangsmaade til fremstilling af diterpenderivater
AR229951A1 (es)	1984-01-31	Procedimiento para la elaboracion de derivados del alcohol 1-alfa-(n-carbamoil-hidroxi-fenoxi)-alquilen-aminometil-arilico
ES494635A0 (es)	1981-08-16	Procedimiento de preparacion de derivados de tiadiazol
ES517332A0 (es)	1984-04-16	Procedimiento para preparar derivados de feniltiadiazinona.
DK377680A (da)	1981-03-07	Fremgangsmaade til fremstilling af kanelsyrederivater
RO78232A (ro)	1982-02-01	Procedeu pentru prepararea unor 4-tiazolidinone
RO76799A (ro)	1981-05-30	PROCEDEU PнNTRU PREPARAREA UNOR FENOLIMINOIMIDAZOLIDINE SUBSTITUITE
IT7850569A0 (it)	1978-08-02	Procedimento di preparazione di un estratto proteico vegetale
MX6291E (es)	1985-03-18	Procedimiento para preparar derivados de n-bencilhalogenoacetamida
AR231289A1 (es)	1984-10-31	Procedimiento para preparar derivados de quinolil-4-1-piperidilo-4-2-etanol o quinolil-4-1-piperidil-4-3-propanol
TR20755A (tr)	1982-06-25	Organik bilesik buhari uygulamasina mahsus usul
MX5826E (es)	1984-07-30	Procedimiento para la obtencion de derivados de fenilimino metil-piridina
ES511058A0 (es)	1983-07-16	Procedimiento para preparar nuevos derivados de fenoxibencilo.
ES504787A0 (es)	1983-10-01	Procedimiento para la obtencion de derivados de diaril-imi- dazol
IT7925426A0 (it)	1979-08-31	Metodo perfezionato di fecondazione artificiale.
ES509744A0 (es)	1983-06-16	Procedimiento para preparar derivados sustituidos de tetrahidropirimidinona.
ES499421A0 (es)	1982-12-16	Procedimiento para preparar derivados de indano
ES515567A0 (es)	1983-10-16	Procedimiento para preparar derivados de fenantreno.
ES505206A0 (es)	1982-08-16	Procedimiento para la obtencion de derivados de 1-azolil-bu-tano fluorados
RO76163A (ro)	1981-08-17	Procedeu pentru prepararea 11beta-hidroxisteroidelor
ES504681A0 (es)	1982-12-01	Procedimiento para preparar derivados de 11- hidroxi-13 oxa-prostaglandina.
ES504338A0 (es)	1982-06-01	Procedimiento de preparacion de derivados difeniletericos
MX5987E (es)	1984-09-14	Procedimiento para la preparacion de derivados de la l-cisteina
AR227341A1 (es)	1982-10-15	Procedimiento para preparar derivados de bis-aminometil-antraquinona
SE7900783L (sv)	1979-08-25	Redskap for behandling av markvexter