DK2646809T3 - Testapparat til udførelse af et assay og software til bærbar enhed - Google Patents
Testapparat til udførelse af et assay og software til bærbar enhed Download PDFInfo
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- DK2646809T3 DK2646809T3 DK12718728.4T DK12718728T DK2646809T3 DK 2646809 T3 DK2646809 T3 DK 2646809T3 DK 12718728 T DK12718728 T DK 12718728T DK 2646809 T3 DK2646809 T3 DK 2646809T3
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/8483—Investigating reagent band
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N2021/1765—Method using an image detector and processing of image signal
- G01N2021/177—Detector of the video camera type
- G01N2021/1776—Colour camera
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
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Claims (17)
1. Testapparat til udførelse af et assay, hvilket testapparat omfatter: en beholder (2), der indeholder et reagens, hvilket reagens reagerer over for en anvendt testprøve ved at udvikle en farve- eller mønstervariation; en bærbar enhed (1), der omfatter en processor og en billedregistreringsenhed (3); hvor processoren er tilpasset til at korrigere billedet for en hvilken som helst rotationsforskydning eller skævhed; hvor processorener er tilpasset til at bestemme en fejlgrad forbundet med en hvilken som helst rotationsforskydning eller skævhed for korrigering af billedet; hvor processoren er konfigureret til at behandle data registreret af billedregistreringsenheden (3) og udlæse et testresultat (4) for den anvendte testprøve; og kendetegnet ved, at testapparatet er konfigureret til at afvise et billede, når en fejlgrad forbundet med en hvilken som helst rotationsforskydning eller skævhed er større end en forudbestemt værdi.
2. Apparat ifølge krav 1, hvor den bærbare enhed (1) omfatter en mobiltelefon, PDA, et digitalkamera eller en bærbar computer.
3. Apparat ifølge krav 1 eller 2, hvor testapparatet er konfigureret til at udføre et immunoassay, for eksempel et lateralt strømningsimmunassay.
4. Apparat ifølge krav 3, hvor testapparatet er konfigureret til at detektere legionella-bakterier.
5. Apparat ifølge et hvilket som helst foregående krav, hvor processoren er konfigureret til at måle den udviklede farve- eller mønstervariation.
6. Apparat ifølge et hvilket som helst af kravene 1 til 5, hvor testapparatet indbefatter en fj embehandlingsenhed til måling af den udviklede farve- eller mønstervariation og beregning af testresultatet (4), og eventuelt hvor: - den bærbare enhed (1) er konfigureret til at sende data til fj embehandlingsenheden og til at modtage og udlæse det beregnede testresultat (4); - fjembehandlingsenheden er tilpasset til at lagre ét af eller dataene og restresultatet (4), og hvor den bærbare enhed (1) eller fj embehandlingsenheden passende er konfigureret til at behandle dataene og testresultatet (4) fra en flerhed af assays eller bærbare enheder (1) til at beregne én/ét eller flere af gruppeværdier eller -parametre.
7. Apparat ifølge et hvilket som helst foregående krav, hvor den bærbare enhed (1) er konfigureret til at ændre billedet for at optimere billedets farverepræsentation, for eksempel ved anvendelse afkomgering og/eller filtrering til et billede (20) for at fjerne elektronisk eller optisk støj fra billedet.
8. Apparat ifølge et hvilket som helst foregående krav, hvor den bærbare enhed (1) er konfigureret til at se bort fra dele af billedet (20) for at reducere behandlingstid.
9. Apparat ifølge et hvilket som helst foregående krav, hvor den bærbare enhed er konfigureret til at styre én eller flere af enhedens lysstyrke, kontrast, forstærkning, farvebalance og blitzindstillingeme under registrering for at opnå et optimalt billede (20) til efterfølgende behandling, for eksempel hvor: processoren er tilpasset til at anvende korrigeringer af lysstyrke, kontrast, skarphed og farvebalance efter billedregistrering; eller processoren er tilpasset til at konvertere et farvebillede til et gråskalabillede eller til et sort og hvidt billede.
10. Apparat ifølge et hvilket som helst foregående krav, hvor den bærbare enhed er konfigureret til at sammenligne to billeder (20) og udlæse testresultatet (4) mindst delvis baseret på sammenligningen, eller hvor den bærbare enhed er konfigureret til at registrere en flerhed af billeder (20), hvor der til hvert anvendes en forskellig eksponeringsindstilling, og eventuelt til at kombinere flerheden af billeder (20).
11. Apparat ifølge et hvilket som helst af kravene 1 til 10, hvor processoren er tilpasset til at bestemme en fejlgrad forbundet med en hvilken som helst rotationsforskydning eller skævhed (20), hvor fejlgraden passende bestemmes ved sammenligning af billedegenskaber med en kendt geometri for beholderen (2); eller hvor den bærbare enhed (1) indbefatter én eller flere retningssensorer og fejlgraden bestemmes baseret på signalet fra retningssensoreme.
12. Apparat ifølge krav 11, hvor testapparatet er konfigureret til at forhindre billedregistrering, når signalet fra retningssensoreme svarer til en retning, der er uden for et/en forudbestemt interval eller værdi.
13. Apparat ifølge et hvilket som helst foregående krav, hvor processoren er tilpasset til at sammenlægge én eller flere pixelværdier i et identificeret område af interesse (22) eller identificere testlinjemes (4) positioner, og eventuelt hvor processoren er tilpasset til at udføre peak-søgning inden for området af interesse (22), hvor processoren passende er tilpasset til at kvantificere teststørrelsen (4) eller kontrollinjer (18) ved anvendelse af en peak-højde eller et peak-område, og eventuelt den kvantificerede størrelse anvendes til at bestemme en koncentrationsmåling for testen.
14. Apparat ifølge et hvilket som helst foregående krav, hvor den bærbare enhed (1) er konfigureret til at sende og/eller lagre tilhørende data sammen med dataene, og eventuelt hvor de tilhørende data omfatter én eller flere af: en dato eller et tidspunkt for billedregistrering; geolokalisering af data for det udførte assay; billedregistreringsenhedens indstillinger; reagensdata og brugergenererede data, og hvor reagensdataene passende omfatter én eller flere af: et batchnummer; en udløbsdato og kalibreringsinformationer, hvilke reagensdata passende angives på beholderen.
15. Apparat ifølge et hvilket som helst foregående krav, hvor den bærbare enhed (1) er konfigureret til at vise en guide- eller skabelonoverlejring, der viser reagensets kontur og/eller ét eller flere områder af interesse; og/eller hvor processoren er konfigureret til at anvende kontrastfarver eller særskilte genstande til at behandle data registreret af billedregistreringsenheden (3) og udlæse testresultatet, eventuelt hvor kontrastfarverne eller de særskilte genstande tilvejebringes af beholderen (2).
16. Software til en bærbar enhed, hvilken software omfatter midler til behandling af et billede (20) af en beholder, der indeholder et reagens, hvilket reagens reagerer over for en anvendt testprøve ved udvikling af en farve- eller mønstervariation, hvor softwaren er tilpasset til at korrigere billedet for en hvilken som helst rotationsforskydning eller skævhed; hvor softwaren er tilpasset til at bestemme en fejlgrad forbundet med enhver rotationsforskydning eller skævhed for korrigering af billedet; hvor softwaren er konfigureret til at måle udviklet farve eller mønstervariation af data registreret af billedregistreringsenheden (3) og udlæse et testresultat (4) for den anvendte testprøve; kendetegnet ved, at softwaren er konfigureret til at afvise et billede når en fejlgrad forbundet med hver af en hvilken som helst rotationsforskydning eller skævhed er større end en forudbestemt værdi.
17. Software ifølge krav 16, der er er konfigureret til at bestemme farvenuancen, den optiske densitet eller skyggen af et billede registret af billedregistreringsenheden.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1105474.9A GB201105474D0 (en) | 2011-03-31 | 2011-03-31 | Testing apparatus |
| PCT/GB2012/050717 WO2012131386A1 (en) | 2011-03-31 | 2012-03-30 | Testing apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2646809T3 true DK2646809T3 (da) | 2018-12-10 |
Family
ID=44071746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12718728.4T DK2646809T3 (da) | 2011-03-31 | 2012-03-30 | Testapparat til udførelse af et assay og software til bærbar enhed |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9903857B2 (da) |
| EP (2) | EP3470825A1 (da) |
| JP (2) | JP6189286B2 (da) |
| KR (2) | KR101954783B1 (da) |
| CN (1) | CN103649731B (da) |
| BR (1) | BR112013025223B1 (da) |
| CA (1) | CA2857424C (da) |
| DK (1) | DK2646809T3 (da) |
| ES (1) | ES2696600T3 (da) |
| GB (1) | GB201105474D0 (da) |
| PT (1) | PT2646809T (da) |
| RU (1) | RU2582268C2 (da) |
| WO (1) | WO2012131386A1 (da) |
Families Citing this family (143)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201105474D0 (en) | 2011-03-31 | 2011-05-18 | Albagaia Ltd | Testing apparatus |
| US9063091B2 (en) | 2012-04-06 | 2015-06-23 | Ixensor Inc. | Test strips and method for reading test strips |
| US20230095831A1 (en) * | 2012-04-17 | 2023-03-30 | i-calQ, LLC | Device for performing an enzyme-based diagnostic test and methods for use thereof |
| US9915616B2 (en) | 2012-07-10 | 2018-03-13 | Fgroupip1, Llc | Method to identify chemical compounds using colorimetric spot tests |
| US9285323B2 (en) | 2012-08-08 | 2016-03-15 | Scanadu Incorporated | Quantifying color changes of chemical test pads induced concentrations of biological analytes under different lighting conditions |
| CA2887206A1 (en) * | 2012-10-05 | 2014-04-10 | Rustem F. Ismagilov | Methods and systems for microfluidics imaging and analysis |
| US9429553B2 (en) * | 2012-10-12 | 2016-08-30 | Industrial Test Systems, Inc. | Processor-based analysis system and method |
| WO2014064685A1 (en) * | 2012-10-22 | 2014-05-01 | Spectrophon Ltd. | Method for detecting analytes |
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| Publication number | Publication date |
|---|---|
| KR102069752B1 (ko) | 2020-01-23 |
| PT2646809T (pt) | 2018-11-27 |
| KR20140074256A (ko) | 2014-06-17 |
| ES2696600T3 (es) | 2019-01-17 |
| JP2014514547A (ja) | 2014-06-19 |
| US9903857B2 (en) | 2018-02-27 |
| RU2582268C2 (ru) | 2016-04-20 |
| CN103649731A (zh) | 2014-03-19 |
| CA2857424A1 (en) | 2012-10-04 |
| BR112013025223B1 (pt) | 2021-09-08 |
| JP6480988B2 (ja) | 2019-03-13 |
| US20140154789A1 (en) | 2014-06-05 |
| GB201105474D0 (en) | 2011-05-18 |
| EP3470825A1 (en) | 2019-04-17 |
| BR112013025223A2 (pt) | 2020-10-20 |
| JP6189286B2 (ja) | 2017-08-30 |
| EP2646809A1 (en) | 2013-10-09 |
| US20180196037A1 (en) | 2018-07-12 |
| CN103649731B (zh) | 2016-04-20 |
| US11698371B2 (en) | 2023-07-11 |
| CA2857424C (en) | 2020-08-25 |
| RU2013148400A (ru) | 2015-05-10 |
| JP2017215337A (ja) | 2017-12-07 |
| EP2646809B1 (en) | 2018-08-29 |
| WO2012131386A1 (en) | 2012-10-04 |
| KR20190026943A (ko) | 2019-03-13 |
| KR101954783B1 (ko) | 2019-03-06 |
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