DK2665486T3 - Sammensætninger til modulering af gamma-c-cytokin-aktivitet - Google Patents
Sammensætninger til modulering af gamma-c-cytokin-aktivitet Download PDFInfo
- Publication number
- DK2665486T3 DK2665486T3 DK12736203.6T DK12736203T DK2665486T3 DK 2665486 T3 DK2665486 T3 DK 2665486T3 DK 12736203 T DK12736203 T DK 12736203T DK 2665486 T3 DK2665486 T3 DK 2665486T3
- Authority
- DK
- Denmark
- Prior art keywords
- cytokin
- compositions
- activity
- modulating gamma
- modulating
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A61K38/10—Peptides having 12 to 20 amino acids
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Birds (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
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- Rheumatology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161433890P | 2011-01-18 | 2011-01-18 | |
| US201161527049P | 2011-08-24 | 2011-08-24 | |
| PCT/US2012/021566 WO2012099886A1 (en) | 2011-01-18 | 2012-01-17 | Compositions and mehthods for modulating gamma-c-cytokine activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2665486T3 true DK2665486T3 (da) | 2020-03-09 |
Family
ID=46516044
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19206731.2T DK3636274T3 (da) | 2011-01-18 | 2012-01-17 | Sammensætninger til modulering af gamma-c-cytokin-aktivitet |
| DK12736203.6T DK2665486T3 (da) | 2011-01-18 | 2012-01-17 | Sammensætninger til modulering af gamma-c-cytokin-aktivitet |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19206731.2T DK3636274T3 (da) | 2011-01-18 | 2012-01-17 | Sammensætninger til modulering af gamma-c-cytokin-aktivitet |
Country Status (19)
| Country | Link |
|---|---|
| US (10) | US9133244B2 (da) |
| EP (3) | EP2665486B1 (da) |
| JP (4) | JP6395379B2 (da) |
| CN (2) | CN109021069A (da) |
| AU (3) | AU2012207456C1 (da) |
| BR (1) | BR112013018046B1 (da) |
| CA (1) | CA2824515C (da) |
| CY (1) | CY1122846T1 (da) |
| DK (2) | DK3636274T3 (da) |
| ES (2) | ES2989085T3 (da) |
| FI (1) | FI3636274T3 (da) |
| HR (1) | HRP20200470T1 (da) |
| LT (1) | LT2665486T (da) |
| PL (2) | PL3636274T3 (da) |
| PT (2) | PT2665486T (da) |
| RS (1) | RS60050B1 (da) |
| SI (1) | SI2665486T1 (da) |
| SM (1) | SMT202000142T1 (da) |
| WO (1) | WO2012099886A1 (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20200470T1 (hr) | 2011-01-18 | 2020-10-02 | Bioniz, Llc | Pripravci za modulaciju aktivnosti gama-c-citokina |
| US9959384B2 (en) | 2013-12-10 | 2018-05-01 | Bioniz, Llc | Methods of developing selective peptide antagonists |
| CN104789527B (zh) * | 2015-05-15 | 2018-05-29 | 江苏杰晟生物科技有限公司 | 一种自体自然杀伤细胞鸡尾酒式培养的制备方法及其试剂盒产品 |
| CN119684428A (zh) * | 2015-10-09 | 2025-03-25 | 比奥尼斯治疗公司 | 调节γC-细胞因子活性 |
| JP2019518786A (ja) * | 2016-05-06 | 2019-07-04 | 牧林 王 | インターロイキンの組み合せ及びその使用 |
| WO2018187499A1 (en) * | 2017-04-07 | 2018-10-11 | Bioniz, Llc | Stable modulators of gamma-c-cytokine activity |
| CN112566664B (zh) * | 2018-07-19 | 2023-08-25 | 国立大学法人东京大学 | Htlv-1相关性脊髓病(ham)治疗或预防剂、及ham的治疗方法 |
| US12459980B2 (en) | 2018-07-25 | 2025-11-04 | AskGene Pharma, Inc. | IL-21 prodrugs and methods of use thereof |
| MX2021001493A (es) | 2018-08-06 | 2021-07-15 | Medikine Inc | Compuestos de fijación al receptor de il-2. |
| CN113710229B (zh) | 2019-02-25 | 2026-01-06 | 芝加哥大学 | 用与抗炎剂连接的ecm亲和肽治疗炎症性和自身免疫性病症的方法和组合物 |
| EP3976182A4 (en) * | 2019-05-03 | 2023-01-18 | Bioniz, LLC | MODULATION OF THE EFFECTS OF GAMMA CYTOKINE SIGNALING FOR THE TREATMENT OF ALOPECIA AND ALOPECIA-ASSOCIATED DISORDERS |
| KR20220020879A (ko) | 2019-06-12 | 2022-02-21 | 에스크진 파마, 아이엔씨. | 새로운 il-15 프로드럭 및 이를 사용하는 방법 |
| KR102265435B1 (ko) * | 2019-08-20 | 2021-06-15 | 주식회사 케어젠 | 피부 미백 활성을 갖는 펩타이드 및 이의 용도 |
| KR20220110207A (ko) | 2019-11-05 | 2022-08-05 | 메디카인 인코포레이티드 | IL-2RβγC 결합 화합물 |
| MX2022005404A (es) | 2019-11-05 | 2022-09-09 | Medikine Inc | Compuestos de fijación a il-2r e il-7r dual. |
| WO2021142471A1 (en) | 2020-01-11 | 2021-07-15 | AskGene Pharma, Inc. | Novel masked cytokines and methods of use thereof |
| IL295304A (en) | 2020-02-03 | 2022-10-01 | Medikine Inc | Il-7 receptor alpha gamma c binding compounds, compositions comprising same and uses thereof |
| JP2023512687A (ja) | 2020-02-03 | 2023-03-28 | メディカイン、インコーポレイテッド | IL-7Rα結合化合物 |
| AU2021254283B2 (en) | 2020-04-10 | 2025-12-11 | Cytomx Therapeutics, Inc. | Activatable cytokine constructs and related compositions and methods |
| EP4172175A4 (en) * | 2020-06-24 | 2024-07-24 | Bioniz Therapeutics, Inc. | Antagonistic peptide targeting il-2, il-9, and il-15 signaling for the treatment of cytokine-release syndrome and cytokine storm associated disorders |
| EP4212163A4 (en) | 2020-09-08 | 2024-09-18 | Dexon Pharmaceuticals Inc. | CYTOKINE STORM INHIBITOR, METHOD FOR USING CYTOKINE STORM INHIBITOR, AND METHOD FOR SCREENING CYTOKINE INHIBITOR |
| JP2024511387A (ja) | 2021-03-16 | 2024-03-13 | シートムエックス セラピューティクス,インコーポレイテッド | マスクした活性化可能サイトカイン構成体ならびに関連する組成物及び方法 |
| JP6974892B1 (ja) | 2021-05-27 | 2021-12-01 | デクソンファーマシューティカルズ株式会社 | 癌悪液質の改善剤および癌悪液質の改善方法 |
| US11999771B2 (en) | 2022-04-07 | 2024-06-04 | Medikine, Inc. | IL-7Rαγc ligand immunoglobulin fusion proteins |
Family Cites Families (87)
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