DK2714034T3 - Sammensætninger omfattende cefepim og tazobactam - Google Patents
Sammensætninger omfattende cefepim og tazobactam Download PDFInfo
- Publication number
- DK2714034T3 DK2714034T3 DK11761404.0T DK11761404T DK2714034T3 DK 2714034 T3 DK2714034 T3 DK 2714034T3 DK 11761404 T DK11761404 T DK 11761404T DK 2714034 T3 DK2714034 T3 DK 2714034T3
- Authority
- DK
- Denmark
- Prior art keywords
- tazobactam
- cefepime
- combination
- resistant
- infection
- Prior art date
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- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 1
- -1 such as for example Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- OHKOGUYZJXTSFX-KZFFXBSXSA-N ticarcillin Chemical compound C=1([C@@H](C(O)=O)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)C=CSC=1 OHKOGUYZJXTSFX-KZFFXBSXSA-N 0.000 description 1
- 229960004659 ticarcillin Drugs 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
- 229960003165 vancomycin Drugs 0.000 description 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- MYPYJXKWCTUITO-LYRMYLQWSA-O vancomycin(1+) Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C([O-])=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)[NH2+]C)[C@H]1C[C@](C)([NH3+])[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-O 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/04—Nitro compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (5)
1. Farmaceutisk sammensætning omfattende (a) cefepim eller et farmaceutisk acceptabelt salt deraf; og (b) tazobactam eller et farmaceutisk acceptabelt salt deraf, hvilken sammensætning er kendetegnet ved, at den omfatter 2 g cefepim og 2 g tazobactam.
2. Farmaceutisk sammensætning ifølge krav 1, til anvendelse ved behandling eller bekæmpelse afen bakterieinfektion hos et individ.
3. Farmaceutisk sammensætning ifølge krav 1, omfattende et farmaceutisk acceptabelt salt af tazobactam, der forefindes som tazobactamnatrium.
4. Farmaceutisk sammensætning ifølge krav 1, hvor sammensætningen er et pulver eller en opløsning.
5. Farmaceutisk sammensætning ifølge krav 1, hvilken sammensætning omfatter et farmaceutisk acceptabelt salt af cefepim, der forefindes som cefepimhydrochlorid, og et farmaceutisk acceptabelt salt af tazobactam, der forefindes som tazobactamnatrium.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1587MU2011 | 2011-05-28 | ||
| PCT/IB2011/053398 WO2012164358A1 (en) | 2011-05-28 | 2011-08-01 | Compositions comprising antibacterial agent and tazobactam |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2714034T3 true DK2714034T3 (da) | 2018-10-08 |
Family
ID=44681394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11761404.0T DK2714034T3 (da) | 2011-05-28 | 2011-08-01 | Sammensætninger omfattende cefepim og tazobactam |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US10525043B2 (da) |
| EP (2) | EP3412289A1 (da) |
| JP (1) | JP5767745B2 (da) |
| KR (3) | KR20140035376A (da) |
| CN (2) | CN103608013A (da) |
| AU (1) | AU2011369802B2 (da) |
| BR (1) | BR112013030282B1 (da) |
| CA (1) | CA2835907C (da) |
| DK (1) | DK2714034T3 (da) |
| ES (1) | ES2690725T3 (da) |
| HU (1) | HUE040049T2 (da) |
| MX (1) | MX356373B (da) |
| NZ (1) | NZ616692A (da) |
| PL (1) | PL2714034T3 (da) |
| PT (1) | PT2714034T (da) |
| RU (1) | RU2593363C2 (da) |
| WO (1) | WO2012164358A1 (da) |
| ZA (1) | ZA201307837B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20160130824A (ko) * | 2014-03-29 | 2016-11-14 | 욱크하르트 리미티드 | 세페파임 또는 술박탐을 포함하는 제약학적 조성물 |
| BR112017022796A2 (pt) * | 2016-03-31 | 2018-07-17 | Wockhardt Ltd | composições antibacterianas e métodos |
| US20180064722A1 (en) * | 2016-03-31 | 2018-03-08 | Wockhardt Limited | Antibacterial compositions |
| RU2017144216A (ru) * | 2016-03-31 | 2019-06-18 | Вокхардт Лимитед | Антибактериальные композиции |
| ES2907796T3 (es) | 2017-10-05 | 2022-04-26 | Fujifilm Corp | Nuevo compuesto de 2-carboxipenam o sal del mismo, composición farmacéutica que contiene dicho compuesto o sal y aplicación del mismo |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1565456A (zh) * | 2003-06-14 | 2005-01-19 | 张哲峰 | 一种头孢吡肟抗菌组合药物 |
| CN1565455A (zh) * | 2003-07-04 | 2005-01-19 | 成都博瑞医药科技开发有限公司 | 治疗产超广谱β－内酰胺酶细菌感染用的抗菌素组合物 |
| KR20070067189A (ko) * | 2004-12-02 | 2007-06-27 | 비너스 레머디스 리미티드 | 주사제에 유용한 베타-락타마제 억제제를 이용한베타-락타마제-매개 항생제 내성에 대처하기 위한 조성물 |
| WO2007086014A1 (en) * | 2006-01-25 | 2007-08-02 | Jegannathan Srinivas | Formulation comprising cefpirome, tazobactam and linezolid |
| WO2007086011A1 (en) | 2006-01-25 | 2007-08-02 | Jegannathan Srinivas | Formulation comprising cefepime, tazobactam and linezolid |
| EP1958630A1 (en) * | 2007-02-13 | 2008-08-20 | LEK Pharmaceuticals d.d. | Antibacterial combination of a tricyclic carbapenem and an antibiotic |
| BRPI0916885B8 (pt) * | 2008-08-28 | 2021-05-25 | Astrazeneca Ab | composição farmacêutica |
-
2011
- 2011-08-01 BR BR112013030282-8A patent/BR112013030282B1/pt active IP Right Grant
- 2011-08-01 HU HUE11761404A patent/HUE040049T2/hu unknown
- 2011-08-01 EP EP18184190.9A patent/EP3412289A1/en not_active Withdrawn
- 2011-08-01 AU AU2011369802A patent/AU2011369802B2/en active Active
- 2011-08-01 US US14/111,627 patent/US10525043B2/en active Active - Reinstated
- 2011-08-01 PT PT11761404T patent/PT2714034T/pt unknown
- 2011-08-01 CA CA2835907A patent/CA2835907C/en active Active
- 2011-08-01 RU RU2013157933/15A patent/RU2593363C2/ru active
- 2011-08-01 CN CN201180071223.1A patent/CN103608013A/zh active Pending
- 2011-08-01 EP EP11761404.0A patent/EP2714034B1/en active Active
- 2011-08-01 ES ES11761404.0T patent/ES2690725T3/es active Active
- 2011-08-01 MX MX2013013079A patent/MX356373B/es active IP Right Grant
- 2011-08-01 WO PCT/IB2011/053398 patent/WO2012164358A1/en not_active Ceased
- 2011-08-01 KR KR1020137029926A patent/KR20140035376A/ko not_active Ceased
- 2011-08-01 NZ NZ616692A patent/NZ616692A/en not_active IP Right Cessation
- 2011-08-01 JP JP2014504401A patent/JP5767745B2/ja active Active
- 2011-08-01 KR KR1020177006744A patent/KR20170032480A/ko not_active Ceased
- 2011-08-01 PL PL11761404T patent/PL2714034T3/pl unknown
- 2011-08-01 DK DK11761404.0T patent/DK2714034T3/da active
- 2011-08-01 KR KR1020187003773A patent/KR101850265B1/ko active Active
- 2011-08-01 CN CN201811566372.5A patent/CN109481439A/zh active Pending
-
2013
- 2013-10-21 ZA ZA2013/07837A patent/ZA201307837B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX356373B (es) | 2018-05-25 |
| CA2835907A1 (en) | 2012-12-06 |
| ES2690725T3 (es) | 2018-11-22 |
| AU2011369802B2 (en) | 2016-09-08 |
| EP3412289A1 (en) | 2018-12-12 |
| US20140162995A1 (en) | 2014-06-12 |
| ZA201307837B (en) | 2015-01-28 |
| CA2835907C (en) | 2017-03-21 |
| EP2714034A1 (en) | 2014-04-09 |
| KR20180016645A (ko) | 2018-02-14 |
| EP2714034B1 (en) | 2018-07-25 |
| RU2013157933A (ru) | 2015-07-10 |
| BR112013030282A2 (pt) | 2017-11-07 |
| NZ616692A (en) | 2015-07-31 |
| CN103608013A (zh) | 2014-02-26 |
| US10525043B2 (en) | 2020-01-07 |
| PL2714034T3 (pl) | 2018-12-31 |
| RU2593363C2 (ru) | 2016-08-10 |
| BR112013030282B1 (pt) | 2020-09-29 |
| JP2014514305A (ja) | 2014-06-19 |
| KR20170032480A (ko) | 2017-03-22 |
| HUE040049T2 (hu) | 2019-02-28 |
| KR101850265B1 (ko) | 2018-04-18 |
| CN109481439A (zh) | 2019-03-19 |
| MX2013013079A (es) | 2013-12-06 |
| JP5767745B2 (ja) | 2015-08-19 |
| AU2011369802A1 (en) | 2013-10-31 |
| PT2714034T (pt) | 2018-10-30 |
| KR20140035376A (ko) | 2014-03-21 |
| WO2012164358A1 (en) | 2012-12-06 |
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