DK272779A - Fremgangsmaade til fremstilling af sekundaere aminer - Google Patents
Fremgangsmaade til fremstilling af sekundaere aminerInfo
- Publication number
- DK272779A DK272779A DK272779A DK272779A DK272779A DK 272779 A DK272779 A DK 272779A DK 272779 A DK272779 A DK 272779A DK 272779 A DK272779 A DK 272779A DK 272779 A DK272779 A DK 272779A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- preparation
- secondary amines
- amines
- Prior art date
Links
- 150000003335 secondary amines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/54—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/86—Ketones containing a keto group bound to a six-membered aromatic ring containing —CHO groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7828208 | 1978-06-28 | ||
| GB7846215 | 1978-11-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK272779A true DK272779A (da) | 1980-02-04 |
Family
ID=26268079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK272779A DK272779A (da) | 1978-06-28 | 1979-06-27 | Fremgangsmaade til fremstilling af sekundaere aminer |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US4478849A (fr) |
| EP (1) | EP0006735B1 (fr) |
| AU (1) | AU523681B2 (fr) |
| CA (1) | CA1159072A (fr) |
| DE (1) | DE2965655D1 (fr) |
| DK (1) | DK272779A (fr) |
| IE (1) | IE48580B1 (fr) |
| IL (1) | IL57678A0 (fr) |
| MY (2) | MY8500958A (fr) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2965655D1 (en) * | 1978-06-28 | 1983-07-21 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
| US4845127A (en) * | 1978-07-03 | 1989-07-04 | Eli Lilly And Company | Phenethanolamines, compositions containing the same and method for effecting weight control |
| EP0028105B1 (fr) * | 1979-10-25 | 1983-01-19 | Beecham Group Plc | Amines secondaires, leur préparation et leur utilisation dans des compositions pharmaceutiques |
| EP0040000B1 (fr) * | 1980-05-08 | 1983-10-12 | Beecham Group Plc | Dérivés d'aryléthanolamine, leur préparation et leur utilisation dans des compositions pharmaceutiques |
| DE3162756D1 (en) * | 1980-05-22 | 1984-04-26 | Beecham Group Plc | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions |
| EP0063004A1 (fr) * | 1981-04-09 | 1982-10-20 | Beecham Group Plc | Amines secondaires, procédé pour leur préparation et compositions pharmaceutiques les contenant |
| EP0070133B1 (fr) * | 1981-07-11 | 1986-05-14 | Beecham Group Plc | Phényléthanolamines secondaires, procédés pour leur préparation et leur application pharmaceutique |
| EP0085514A3 (fr) * | 1982-01-28 | 1984-02-29 | Beecham Group Plc | Compositions contenant un bêta-antagoniste et un bêta-agoniste, procédé pour leur préparation et leur utilisation pour le traitement d'êtres humains et d'animaux obèses |
| EP0089154A3 (fr) * | 1982-03-12 | 1984-08-08 | Beecham Group Plc | Dérivés d'éthanolamine, leur fabrication et leur utilisation en compositions pharmaceutiques |
| CA1219865A (fr) * | 1982-05-14 | 1987-03-31 | Leo Alig | Derives de phenethanolamine d'aziridine |
| EP0099707B1 (fr) * | 1982-07-16 | 1986-12-10 | Beecham Group Plc | Dérivés d'éther 2-aminoéthyles, leurs procédés de préparation et compositions pharmaceutiques les contenant |
| US4849453A (en) * | 1983-01-31 | 1989-07-18 | Eli Lilly And Company | Growth promotion |
| US4690951A (en) * | 1983-01-31 | 1987-09-01 | Eli Lilly And Company | Growth promotion |
| US4657929A (en) * | 1983-10-25 | 1987-04-14 | Fisons Plc | Compounds |
| EP0142102B1 (fr) * | 1983-11-04 | 1987-09-23 | Beecham Group Plc | Amines tertiaires |
| US4562206A (en) * | 1983-12-23 | 1985-12-31 | Key Pharmaceuticals, Inc. | Orally effective inotropic compounds |
| NL8501124A (nl) * | 1984-04-17 | 1985-11-18 | Glaxo Group Ltd | Fenethanolamine-verbindingen, de bereiding daarvan, alsmede farmaceutische preparaten waarvan zij een component vormen. |
| IN161689B (fr) * | 1984-06-18 | 1988-01-16 | Sumitomo Chemical Co | |
| US4943591A (en) * | 1984-10-17 | 1990-07-24 | Glaxo Group Limited | Dichloroaniline derivatives |
| PT82120B (en) * | 1985-03-01 | 1988-06-16 | Beecham Group Plc | Process for preparing veterinary formulations containing ethanolamine derivatives |
| GB8519154D0 (en) * | 1985-07-30 | 1985-09-04 | Ici Plc | Aromatic ethers |
| EP0286703A1 (fr) * | 1987-04-14 | 1988-10-19 | Klinge Pharma GmbH | Dérivés de l'acide benzoique, leur procédé de fabrication et leur utilisation comme médicaments |
| EP0244062A3 (fr) * | 1986-03-03 | 1990-06-20 | Beecham Group Plc | Utilisation des dérivés de l'aryléthanolamine pour le traitement de l'athérosclérose |
| EG18188A (en) * | 1986-05-01 | 1992-09-30 | Pfizer Ltd | Process for preparation anti-arhythmia agents |
| CA1287061C (fr) * | 1986-06-27 | 1991-07-30 | F. Hoffmann-La Roche Ag | Derives de pyridineethanolamines |
| GB8615995D0 (en) * | 1986-07-01 | 1986-08-06 | Glaxo Group Ltd | Veterinary preparations |
| GB8714901D0 (en) * | 1986-07-23 | 1987-07-29 | Ici Plc | Amide derivatives |
| EP0300290B1 (fr) * | 1987-07-21 | 1991-12-18 | F. Hoffmann-La Roche Ag | Phénoxypropanolamines |
| US5108363A (en) * | 1988-02-19 | 1992-04-28 | Gensia Pharmaceuticals, Inc. | Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist |
| US5453418A (en) * | 1988-03-07 | 1995-09-26 | Eli Lilly And Company | Ractopamine and growth hormone combinations |
| GB8925032D0 (en) * | 1989-11-06 | 1989-12-28 | Ici Plc | Chemical compounds |
| US5356913A (en) * | 1990-02-09 | 1994-10-18 | The Upjohn Company | Use of insulin sensitizing agents to treat hypertension |
| WO1991012003A1 (fr) * | 1990-02-09 | 1991-08-22 | The Upjohn Company | Utilisation d'agents de sensibilisation a l'insuline afin de traiter l'hypertension |
| US5106867A (en) * | 1990-05-04 | 1992-04-21 | American Cyanamid Company | Method of increasing lean meat in edible animals |
| US5151439A (en) * | 1990-05-04 | 1992-09-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
| US5245053A (en) * | 1990-05-04 | 1993-09-14 | American Cyanamid Company | Substituted 5-(2-(2-aryl-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxoles |
| US5061727A (en) | 1990-05-04 | 1991-10-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
| GB9111426D0 (en) * | 1991-05-28 | 1991-07-17 | Ici Plc | Chemical compounds |
| US5502078A (en) * | 1991-05-28 | 1996-03-26 | Zeneca Limited | Chemical compounds |
| NO179246C (no) * | 1991-11-20 | 1996-09-04 | Sankyo Co | Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav |
| US5451677A (en) * | 1993-02-09 | 1995-09-19 | Merck & Co., Inc. | Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity |
| US5321036A (en) * | 1993-02-10 | 1994-06-14 | Bristol-Myers Squibb Company | Thiazole and oxazole-based β3 adrenergic receptor agonists |
| BR9406823A (pt) * | 1993-06-14 | 1996-03-26 | Pfizer | Aminas secundárias e agentes anti-diabéticos e antiobesidade |
| US5563171A (en) * | 1993-11-05 | 1996-10-08 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists |
| US5578638A (en) * | 1993-11-05 | 1996-11-26 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists |
| US5541197A (en) * | 1994-04-26 | 1996-07-30 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| US5705515A (en) * | 1994-04-26 | 1998-01-06 | Merck & Co., Inc. | Substituted sulfonamides as selective β-3 agonists for the treatment of diabetes and obesity |
| US5627200A (en) * | 1994-09-26 | 1997-05-06 | Pfizer Inc | β3 -Adrenoceptor agonists and antagonists for the treatment of intestinal motility disorders, depression, prostate disease and dyslipidemia |
| ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
| US6075040A (en) * | 1996-09-05 | 2000-06-13 | Eli Lilly And Company | Selective β3 adrenergic agonists |
| ES2171839T3 (es) | 1996-09-05 | 2002-09-16 | Lilly Co Eli | Analogos de carbazol como agonistas adrenergicos selectivos de beta3. |
| US5908830A (en) * | 1996-10-31 | 1999-06-01 | Merck & Co., Inc. | Combination therapy for the treatment of diabetes and obesity |
| ATE266639T1 (de) * | 1997-10-17 | 2004-05-15 | Yamanouchi Pharma Co Ltd | Amidderivate oder deren salze |
| CO5011072A1 (es) * | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
| GB9812709D0 (en) * | 1998-06-13 | 1998-08-12 | Glaxo Group Ltd | Chemical compounds |
| US7709677B2 (en) * | 2001-01-31 | 2010-05-04 | Glaxosmithkline Llc | Process of preparing arylethanoldiamines |
| GB0102407D0 (en) | 2001-01-31 | 2001-03-14 | Glaxo Group Ltd | Process |
| EP1236723A1 (fr) * | 2001-03-01 | 2002-09-04 | Pfizer Products Inc. | Dérivés de sulfamide utiles comme agonistes de beta3 et leurs applications pharmaceutiques |
| KR100816527B1 (ko) * | 2001-09-12 | 2008-04-10 | 한국화학연구원 | 페닐테트라졸 유도체로 치환된 β-아미노알코올 화합물 |
| WO2003072573A1 (fr) * | 2002-02-27 | 2003-09-04 | Pfizer Products Inc. | Formes cristallines de (r)-2-(2-(4-oxazol-4-yl-phenoxy)-ethylamino)-1-pyridin-3-yl-ethanol |
| WO2003072547A1 (fr) | 2002-02-27 | 2003-09-04 | Pfizer Products Inc. | Procedes et intermediaires utiles dans la preparation d'agonistes du recepteur $g(b)3 adrenergique |
| US6864268B2 (en) | 2002-02-27 | 2005-03-08 | Pfizer Inc. | β3 adrenergic receptor agonists |
| EP1577291A1 (fr) * | 2004-03-17 | 2005-09-21 | Pfizer Limited | Dérivés béta-2 agonistes de la phényléthanolamine |
| BRPI0508927A (pt) * | 2004-03-17 | 2007-08-14 | Pfizer | compostos úteis para o tratamento de doenças |
| EP1730103B1 (fr) * | 2004-03-23 | 2010-05-26 | Pfizer Limited | Derives du formamide utile comme adrenocepteur |
| DE102004021779A1 (de) * | 2004-04-30 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| ES2265276B1 (es) | 2005-05-20 | 2008-02-01 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
| ES2296516B1 (es) * | 2006-04-27 | 2009-04-01 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
| ES2306595B1 (es) | 2007-02-09 | 2009-09-11 | Laboratorios Almirall S.A. | Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2. |
| ES2320961B1 (es) * | 2007-11-28 | 2010-03-17 | Laboratorios Almirall, S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2. |
| EP2096105A1 (fr) * | 2008-02-28 | 2009-09-02 | Laboratorios Almirall, S.A. | Dérivés de 4-(2-amino-1-hydroxyethyl)phénol en tant qu'antagonistes du récepteur adrénergique b2 |
| UY32297A (es) | 2008-12-22 | 2010-05-31 | Almirall Sa | Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico |
| EP2228368A1 (fr) | 2009-03-12 | 2010-09-15 | Almirall, S.A. | Procédé de fabrication de 5-(2-{[6-(2,2-difluoro-2-ph2nyl2thoxy)hexyl]amino}-1-hydroxy2thyl)-8-hydroxyquinolin-2(1h)-one |
| JP2013532185A (ja) | 2010-07-12 | 2013-08-15 | ファイザー・リミテッド | 化合物 |
| US9522129B2 (en) | 2010-08-03 | 2016-12-20 | Velicept Therapeutics, Inc. | Pharmaceutical Combination |
| US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
| EP2578570A1 (fr) | 2011-10-07 | 2013-04-10 | Almirall, S.A. | Nouveau procédé de fabrication de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy)hexyl]amino}-1-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one via de nouveaux intermédiaires de synthèse |
| EP2641900A1 (fr) | 2012-03-20 | 2013-09-25 | Almirall, S.A. | Nouvelles formes polymorphes de héminapadisylate de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy) hexyl]amino}-1-(R)-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one en tant qu'agoniste du récepteur adrénergique ß2 |
| ES2394349B1 (es) | 2012-08-29 | 2013-11-04 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar |
| HK1245117A1 (zh) | 2014-12-03 | 2018-08-24 | Velicept Therapeutics, Inc. | 使用调节释放索拉贝隆用於下尿路症状的组合物和方法 |
| ES2967863T3 (es) | 2015-10-23 | 2024-05-06 | B3Ar Therapeutics Inc | Ion dipolar de solabegron y usos del mismo |
| CN110734382B (zh) * | 2019-10-09 | 2024-02-20 | 苏州弘森药业股份有限公司 | 一种合成特布他林的方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US28229A (en) * | 1860-05-08 | Improvement in air-pumps for steam-engines | ||
| US2205530A (en) * | 1937-01-02 | 1940-06-25 | Bilhuber Inc E | Chemical compounds beta-(ortho-hydroxyphenyl)-isopropylamines |
| DE894396C (de) * | 1944-05-21 | 1953-10-26 | Troponwerke Dinklage & Co | Verfahren zur Herstellung von 1-(o-, m- oder p-Oxyphenyl)-1-oxy-2-aralkylamino-aethanen |
| USRE28229E (en) | 1965-06-28 | 1974-11-05 | Ili-axnhr | |
| US3976695A (en) * | 1970-01-13 | 1976-08-24 | Smithkline Corporation | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols |
| US3856857A (en) * | 1970-02-13 | 1974-12-24 | En Nom Collectif Science Union | Amino acids and their derivatives |
| GB1301134A (en) * | 1970-07-18 | 1972-12-29 | Pfizer Ltd | SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES |
| US4086272A (en) * | 1970-07-18 | 1978-04-25 | Pfizer Inc. | Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants |
| US3809752A (en) * | 1971-03-24 | 1974-05-07 | W Fishman | Anti-obesity process |
| DE2143204C3 (de) * | 1971-08-28 | 1979-09-27 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis |
| US3801631A (en) * | 1972-02-16 | 1974-04-02 | Mead Johnson & Co | 2'-hydroxy-5'-(1-hydroxy-2-(2-methyl-1-phenyl-2-propylamino)ethyl)meth-anesulfonanilide and its salts |
| US3870715A (en) * | 1972-03-09 | 1975-03-11 | Nikolaus R Hansl | Substituted amino ethyl meta benzoic acid esters |
| US3818101A (en) * | 1972-08-28 | 1974-06-18 | Smithkline Corp | Methods for improving the feed intake of meat producing animals |
| BE788850A (fr) * | 1972-09-15 | 1973-03-15 | Hoffmann La Roche | Derives d'acide benzoique |
| GB1471431A (en) * | 1974-04-30 | 1977-04-27 | Science Union & Cie | Alkanolamine derivatives processes for their preparation and pharmaceutical compositions containing them |
| US4052506A (en) * | 1975-08-05 | 1977-10-04 | Smithkline Corporation | Pharmaceutical compositions and method of producing anti-parkinsonism activity |
| US4146638A (en) * | 1976-02-17 | 1979-03-27 | Boehringer Ingelheim Gmbh | N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines |
| US4044150A (en) * | 1976-06-18 | 1977-08-23 | Mead Johnson & Company | Antihypertensive 4'-[1-hydroxy-2-[(1-phenoxy ethyl)-amino]ethyl]methanesulfonanilide and salts thereof and therapeutic use |
| DD144050A5 (de) * | 1978-06-05 | 1980-09-24 | Ciba Geigy Ag | Verfahren zur herstellung von n-alkylierten aminoalkoholen |
| DE2965655D1 (en) * | 1978-06-28 | 1983-07-21 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
| DK269079A (da) * | 1978-07-03 | 1980-02-01 | Lilly Co Eli | Fremgangsmaade til fremstilling af phenethanolaminer |
| US4391826A (en) * | 1978-07-03 | 1983-07-05 | Eli Lilly And Company | Phenethanolamines, compositions containing the same, and method for effecting weight control |
| IL57671A (en) * | 1978-07-03 | 1982-11-30 | Lilly Co Eli | Phenethanolamines,process for their preparation and pharmaceutical and animal feed compositions containing the same |
| CA1120058A (fr) * | 1978-07-03 | 1982-03-16 | Jack Mills | Phenetolamines, compositions et potentialisation des medicaments oncolytiques |
| EP0028105B1 (fr) * | 1979-10-25 | 1983-01-19 | Beecham Group Plc | Amines secondaires, leur préparation et leur utilisation dans des compositions pharmaceutiques |
| DE3162756D1 (en) * | 1980-05-22 | 1984-04-26 | Beecham Group Plc | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions |
-
1979
- 1979-06-21 DE DE7979301197T patent/DE2965655D1/de not_active Expired
- 1979-06-21 EP EP79301197A patent/EP0006735B1/fr not_active Expired
- 1979-06-27 CA CA000330733A patent/CA1159072A/fr not_active Expired
- 1979-06-27 DK DK272779A patent/DK272779A/da unknown
- 1979-06-27 IL IL57678A patent/IL57678A0/xx unknown
- 1979-06-28 AU AU48498/79A patent/AU523681B2/en not_active Ceased
- 1979-08-08 IE IE1179/79A patent/IE48580B1/en unknown
-
1983
- 1983-03-10 US US06/474,199 patent/US4478849A/en not_active Expired - Fee Related
-
1985
- 1985-10-08 US US06/785,608 patent/US4654371A/en not_active Expired - Fee Related
- 1985-12-30 MY MY958/85A patent/MY8500958A/xx unknown
- 1985-12-30 MY MY959/85A patent/MY8500959A/xx unknown
-
1986
- 1986-12-01 US US06/936,714 patent/US4753962A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU523681B2 (en) | 1982-08-12 |
| DE2965655D1 (en) | 1983-07-21 |
| EP0006735A1 (fr) | 1980-01-09 |
| IE791179L (en) | 1979-12-28 |
| US4478849A (en) | 1984-10-23 |
| MY8500958A (en) | 1985-12-31 |
| MY8500959A (en) | 1985-12-31 |
| CA1159072A (fr) | 1983-12-20 |
| US4753962A (en) | 1988-06-28 |
| EP0006735B1 (fr) | 1983-06-15 |
| IE48580B1 (en) | 1985-03-06 |
| US4654371A (en) | 1987-03-31 |
| AU4849879A (en) | 1980-01-03 |
| IL57678A0 (en) | 1979-10-31 |
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