DK27383A - Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner - Google Patents

Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner Download PDF

Info

Publication number: DK27383A
Authority: DK; Denmark
Prior art keywords: pyridines; procedure; preparing pyrazole; pyrazole; preparing
Prior art date: 1982-02-17

Application number

DK27383A

Other languages

Danish (da)

English (en)

Other versions

DK27383D0 (da

Inventor

Giorgio Winters

Alberto Sala

Domenico Barone

Original Assignee

Lepetit Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-02-17

Filing date

1983-01-25

Publication date

1983-08-18

1983-01-25 Application filed by Lepetit Spa filed Critical Lepetit Spa

1983-01-25 Publication of DK27383D0 publication Critical patent/DK27383D0/da

1983-08-18 Publication of DK27383A publication Critical patent/DK27383A/da

Links

RQMWVVBHJMUJNZ-UHFFFAOYSA-N 4-chloropyridin-2-amine Chemical compound NC1=CC(Cl)=CC=N1 RQMWVVBHJMUJNZ-UHFFFAOYSA-N 0.000 title 1
WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 title 1
239000013543 active substance Substances 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
230000003276 anti-hypertensive effect Effects 0.000 abstract 1
230000003177 cardiotonic effect Effects 0.000 abstract 1
239000003874 central nervous system depressant Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003176 neuroleptic agent Substances 0.000 abstract 1
230000000701 neuroleptic effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003222 pyridines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Anesthesiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK27383A 1982-02-17 1983-01-25 Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner DK27383A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8204722		1982-02-17

Publications (2)

Publication Number	Publication Date
DK27383D0 DK27383D0 (da)	1983-01-25
DK27383A true DK27383A (da)	1983-08-18

Family

ID=10528419

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK27383A DK27383A (da)	1982-02-17	1983-01-25	Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner

Country Status (16)

Country	Link
US (1)	US4500525A (cs)
EP (1)	EP0086422B1 (cs)
JP (1)	JPS58152885A (cs)
KR (1)	KR900006853B1 (cs)
AT (1)	ATE30027T1 (cs)
AU (1)	AU563591B2 (cs)
CA (1)	CA1225646A (cs)
DE (1)	DE3373904D1 (cs)
DK (1)	DK27383A (cs)
ES (3)	ES519832A0 (cs)
GR (1)	GR78080B (cs)
IE (1)	IE55156B1 (cs)
IL (1)	IL67785A0 (cs)
NZ (1)	NZ203302A (cs)
PH (1)	PH23645A (cs)
ZA (1)	ZA83628B (cs)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5137890A (en) *	1990-02-14	1992-08-11	Ortho Pharmaceutical Corporation	4-phenyl tetrahydropyrido(4,3-d)pyrimidines
US5264576A (en) *	1992-10-22	1993-11-23	Hoechst-Roussel Pharmaceuticals Incorporated	Pyrazolo[4,3-c]pyridines which are intermediates
DE19834044A1 (de) *	1998-07-29	2000-02-03	Bayer Ag	Neue substituierte Pyrazolderivate
US20070117785A1 (en) *	2000-08-14	2007-05-24	Butler Christopher R	Substituted pyrazoles and methods of treatment with substituted pyrazoles
US20050101587A9 (en) *	2000-08-14	2005-05-12	Butler Christopher R.	Method for treating allergies using substituted pyrazoles
RU2317988C2 (ru)	2000-08-14	2008-02-27	Орто-Макнейл Фармасьютикал, Инк.	Замещенные пиразолы, фармацевтическая композиция на их основе, применение фармацевтической композиции и способ ингибирования активности катепсина s
EP1309591B1 (en) *	2000-08-14	2007-01-24	Ortho-McNeil Pharmaceutical, Inc.	Substituted pyrazoles
US7332494B2 (en)	2000-08-14	2008-02-19	Janssen Pharmaceutica, N.V.	Method for treating allergies using substituted pyrazoles
US20070105841A1 (en) *	2000-08-14	2007-05-10	Breitenbucher J G	Method for treating allergies using substituted pyrazoles
NZ524192A (en) *	2000-08-14	2005-02-25	Ortho Mcneil Pharm Inc	Substituted pyrazoles
HK1053129A1 (zh)	2000-09-06	2003-10-10	Ortho-Mcneil Pharmaceutical, Inc.	治疗变态反应的方法
DK1315491T3 (da) *	2000-09-06	2006-10-30	Ortho Mcneil Pharm Inc	Anvendelse af substituerede pyrazoler til fremstilling af et medikament til behandling af allergier
RU2286343C2 (ru) *	2001-08-10	2006-10-27	Орто-Макнейл Фармасьютикал, Инк.	Замещенные пиразолы
US7122552B2 (en) *	2002-05-30	2006-10-17	Vertex Pharmaceuticals Incorporated	Inhibitors of JAK and CDK2 protein kinases
AU2003244632A1 (en) *	2002-07-25	2004-02-25	Pharmacia Italia S.P.A.	Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
EP2243781A1 (en) *	2003-05-30	2010-10-27	Vertex Pharmaceuticals, Inc.	Pyrazolopyridine derivatives as inhibitors of JAK and CDK2 protein kinases
MXPA06003150A (es)	2003-09-17	2006-08-31	Johnson & Johnson	Compuestos heterociclicos fusionados.
WO2005030776A1 (en)	2003-09-23	2005-04-07	Vertex Pharmaceuticals Incorporated	Pyrazolopyrrole derivatives as protein kinase inhibitors
KR100838692B1 (ko)	2007-07-11	2008-06-16	한국화학연구원	7-(3′,4′-디알콕시페닐)-4,5,6,7-테트라히드로피라졸로[1,5-ａ]피리미딘 화합물, 이의 제조방법 및 이를 포함하는천식 및 만성폐쇄성 폐질환을 포함한 염증관련 질환,관절염, 아토피 피부염, 암 및 뇌질환의 치료 및 예방을위한 약제학적 조성물
EP2615916B1 (en) *	2010-09-16	2017-01-04	Merck Sharp & Dohme Corp.	Fused pyrazole derivatives as novel erk inhibitors
WO2013037736A1 (en)	2011-09-12	2013-03-21	Sanofi	Indanyl-substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
JP5893143B2 (ja) *	2011-09-12	2016-03-23	サノフイ	インダニル置換の４，５，６，７−テトラヒドロ−１Ｈ−ピラゾロ［４，３−ｃ］ピリジン、医薬としてのその使用、及びそれらを含む医薬製剤
EP2755973B1 (en) *	2011-09-16	2015-11-04	Sanofi	Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
WO2013037914A1 (en)	2011-09-16	2013-03-21	Sanofi	Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
WO2016109684A2 (en)	2014-12-30	2016-07-07	Novira Therapeutics, Inc.	Derivatives and methods of treating hepatitis b infections
CN109476663B (zh) *	2016-05-24	2021-11-09	基因泰克公司	用于治疗癌症的吡唑并吡啶衍生物
ES2817426T3 (es)	2016-06-29	2021-04-07	Novira Therapeutics Inc	Derivados de oxadiazepinona y su uso en el tratamiento de infecciones por hepatitis B
MA45550A (fr)	2016-06-29	2019-05-08	Novira Therapeutics Inc	Dérivés de diazépinone et leur utilisation dans le traitement des infections par l'hépatite b
JP7141130B2 (ja)	2017-05-31	2022-09-22	ケモセントリックス，インコーポレイティド	Ｃ５ａ阻害剤としての６－５融合環
US10828285B2 (en) *	2017-12-22	2020-11-10	Chemocentryx, Inc.	Diaryl substituted 6,5-fused ring compounds as C5aR inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3852279A (en) *	1973-03-12	1974-12-03	Squibb & Sons Inc	7-substituted -3,3a,4,5,6,7-hexahydro-3-substituted-2h- pyrazolo (4,3-c)pyridines

1983
- 1983-01-25 DK DK27383A patent/DK27383A/da not_active Application Discontinuation
- 1983-01-31 ZA ZA83628A patent/ZA83628B/xx unknown
- 1983-01-31 IL IL67785A patent/IL67785A0/xx unknown
- 1983-02-03 GR GR70399A patent/GR78080B/el unknown
- 1983-02-06 DE DE8383101109T patent/DE3373904D1/de not_active Expired
- 1983-02-06 EP EP83101109A patent/EP0086422B1/en not_active Expired
- 1983-02-06 AT AT83101109T patent/ATE30027T1/de not_active IP Right Cessation
- 1983-02-08 PH PH28489A patent/PH23645A/en unknown
- 1983-02-10 AU AU11305/83A patent/AU563591B2/en not_active Expired - Fee Related
- 1983-02-15 KR KR1019830000609A patent/KR900006853B1/ko not_active Expired
- 1983-02-15 US US06/466,701 patent/US4500525A/en not_active Expired - Fee Related
- 1983-02-16 NZ NZ203302A patent/NZ203302A/en unknown
- 1983-02-16 IE IE328/83A patent/IE55156B1/en not_active IP Right Cessation
- 1983-02-16 CA CA000421751A patent/CA1225646A/en not_active Expired
- 1983-02-16 ES ES519832A patent/ES519832A0/es active Granted
- 1983-02-17 JP JP58023893A patent/JPS58152885A/ja active Granted
1984
- 1984-04-27 ES ES531980A patent/ES531980A0/es active Granted
- 1984-04-27 ES ES531981A patent/ES8507547A1/es not_active Expired

Also Published As

Publication number	Publication date
US4500525A (en)	1985-02-19
DE3373904D1 (en)	1987-11-05
ES8500273A1 (es)	1984-10-01
KR900006853B1 (ko)	1990-09-22
AU563591B2 (en)	1987-07-16
EP0086422B1 (en)	1987-09-30
ES519832A0 (es)	1984-10-01
PH23645A (en)	1989-09-27
NZ203302A (en)	1986-08-08
JPH0412269B2 (cs)	1992-03-04
CA1225646A (en)	1987-08-18
EP0086422A2 (en)	1983-08-24
JPS58152885A (ja)	1983-09-10
ATE30027T1 (de)	1987-10-15
ES531981A0 (es)	1985-09-01
DK27383D0 (da)	1983-01-25
GR78080B (cs)	1984-09-26
EP0086422A3 (en)	1984-03-28
KR840003636A (ko)	1984-09-15
ES8507546A1 (es)	1985-09-01
IL67785A0 (en)	1983-05-15
IE55156B1 (en)	1990-06-20
ZA83628B (en)	1983-12-28
AU1130583A (en)	1983-08-25
ES531980A0 (es)	1985-09-01
ES8507547A1 (es)	1985-09-01
IE830328L (en)	1983-08-17

Legal Events

Date	Code	Title	Description
1993-09-27	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK27383A (da)	1983-08-18	Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner
IL72120A0 (en)	1984-10-31	2-pyrimidinyl-1-piperazine derivatives,their preparation and pharmaceutical compositions containing them
NO20001940D0 (no)	2000-04-13	Bicykliske kinase-inhibitorer
HUT70505A (en)	1995-10-30	Pyrrolo[2,3-d]pyrimidine derivatives, pharmaceutical compositions containing them and process for preparing them
ES8200094A1 (es)	1981-10-16	Procedimiento para la obtencion de alquilureas
IL64472A0 (en)	1982-03-31	Pharmaceutical compositions containing tricyclic cytosin derivatives,certain new compounds of this class and their production
JO1406B1 (en)	1986-11-30	Chemical compounds
ATE69228T1 (de)	1991-11-15	Amidabkoemmlinge.
ES8305783A1 (es)	1983-03-16	Procedimiento para la obtencion de derivados de aminociclitol saturados.
ES8800217A1 (es)	1987-10-16	Procedimiento para la preparacion de acidos 4-(isoxazolil)-tiazol-2-oxamicos y sus derivados
ES8600768A1 (es)	1985-10-16	Imidazotiadiazolalquencarboxiamidas
JPS53101328A (en)	1978-09-04	Succinic acid anhydride derivatives and process for their preparation