DK276184A - Fremstilling af human insulinlignende vaekstfaktor (igf) og epidermal vaekstfaktor (egf) via rekombinant-dna-teknologi - Google Patents

Fremstilling af human insulinlignende vaekstfaktor (igf) og epidermal vaekstfaktor (egf) via rekombinant-dna-teknologi Download PDF

Info

Publication number: DK276184A
Authority: DK; Denmark
Prior art keywords: growth factor; igf; egf; preparation; recombinant dna
Prior art date: 1983-06-06

Application number

DK276184A

Other languages

English (en)

Other versions

DK172480B1 (da

DK276184D0 (da

Inventor

James Mon Lee

Axel Ullrich

Original Assignee

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-06-06

Filing date

1984-06-04

Publication date

1985-01-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27053789&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK276184(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1984-06-04 Application filed by Genentech Inc filed Critical Genentech Inc

1984-06-04 Publication of DK276184D0 publication Critical patent/DK276184D0/da

1985-01-21 Publication of DK276184A publication Critical patent/DK276184A/da

1998-10-05 Application granted granted Critical

1998-10-05 Publication of DK172480B1 publication Critical patent/DK172480B1/da

Links

108020004511 Recombinant DNA Proteins 0.000 title 1
239000003102 growth factor Substances 0.000 title 1
VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Mycology (AREA)
Toxicology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)

DK198402761A 1983-06-06 1984-06-04 Fremgangsmåde til fremstilling af moden human insulinlignende vækstfaktor (IGF-I) eller et human IGF-I-fusionsprotein, eksp DK172480B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US50135383A	1983-06-06	1983-06-06
US50135383		1983-06-06
US50607883A	1983-06-20	1983-06-20
US50607883		1983-06-20

Publications (3)

Publication Number	Publication Date
DK276184D0 DK276184D0 (da)	1984-06-04
DK276184A true DK276184A (da)	1985-01-21
DK172480B1 DK172480B1 (da)	1998-10-05

Family

ID=27053789

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198402761A DK172480B1 (da)	1983-06-06	1984-06-04	Fremgangsmåde til fremstilling af moden human insulinlignende vækstfaktor (IGF-I) eller et human IGF-I-fusionsprotein, eksp

Country Status (10)

Country	Link
US (3)	US6331609B1 (da)
EP (1)	EP0128733B1 (da)
JP (2)	JP2608870B2 (da)
KR (1)	KR850000525A (da)
AU (1)	AU594301B2 (da)
DE (1)	DE3485693D1 (da)
DK (1)	DK172480B1 (da)
ES (1)	ES8603955A1 (da)
IE (1)	IE58317B1 (da)
IL (1)	IL71991A (da)

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1984
- 1984-06-01 IL IL7199184A patent/IL71991A/en unknown
- 1984-06-04 DK DK198402761A patent/DK172480B1/da not_active IP Right Cessation
- 1984-06-05 EP EP84303783A patent/EP0128733B1/en not_active Expired - Lifetime
- 1984-06-05 KR KR1019840003134A patent/KR850000525A/ko not_active Ceased
- 1984-06-05 DE DE8484303783T patent/DE3485693D1/de not_active Expired - Lifetime
- 1984-06-05 IE IE140084A patent/IE58317B1/en not_active IP Right Cessation
- 1984-06-06 JP JP59117422A patent/JP2608870B2/ja not_active Expired - Lifetime
- 1984-06-06 AU AU29133/84A patent/AU594301B2/en not_active Expired
- 1984-06-06 ES ES533170A patent/ES8603955A1/es not_active Expired
1994
- 1994-06-08 JP JP6126496A patent/JPH0759578A/ja active Pending
1995
- 1995-06-05 US US08/464,361 patent/US6331609B1/en not_active Ceased
- 1995-06-05 US US08/464,255 patent/US6331414B1/en not_active Expired - Lifetime
2003
- 2003-06-13 US US10/461,712 patent/USRE39355E1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0128733A1 (en)	1984-12-19
DE3485693D1 (de)	1992-06-11
JPH0759578A (ja)	1995-03-07
IL71991A0 (en)	1984-10-31
ES533170A0 (es)	1986-01-16
US6331414B1 (en)	2001-12-18
AU594301B2 (en)	1990-03-08
USRE39355E1 (en)	2006-10-17
IE58317B1 (en)	1993-09-08
DK172480B1 (da)	1998-10-05
DK276184D0 (da)	1984-06-04
IE841400L (en)	1984-12-06
JPS6069029A (ja)	1985-04-19
JP2608870B2 (ja)	1997-05-14
US6331609B1 (en)	2001-12-18
AU2913384A (en)	1984-12-13
ES8603955A1 (es)	1986-01-16
EP0128733B1 (en)	1992-05-06
KR850000525A (ko)	1985-02-27
IL71991A (en)	1994-05-30

Legal Events

Date	Code	Title	Description
2004-06-21	PUP	Patent expired

Publication	Publication Date	Title
DK276184A (da)	1985-01-21	Fremstilling af human insulinlignende vaekstfaktor (igf) og epidermal vaekstfaktor (egf) via rekombinant-dna-teknologi
DK162385A (da)	1985-10-12	Implanterbare praeparater af regulatoriske peptider med styret frigoerelse og fremgangsmaade til fremstilling heraf
DK166087D0 (da)	1987-04-01	Proteiner og fremgangsmaade til fremstilling deraf
DK478786D0 (da)	1986-10-07	Cystein-forarmede muteiner af biologisk aktive humantumornekrosefaktorproteiner
DK70385A (da)	1985-09-02	Bakteriepraeparat og fremgangsmaade til fremstilling deraf
DK294685A (da)	1985-12-30	Apparat og fremgangsmaade til pulseret administration af vaekstfremmende midler
DK579787A (da)	1988-05-06	Stabiliserede praeparater indeholdende epidermal vaekstfaktor
DK559586A (da)	1987-05-23	Fremgangsmaade til direkte indfoering af dna i plastider og mitochondrier
DK300782A (da)	1982-07-05	Dyrefoderblok fremstillet af melasse og calciumoxid
DK314786D0 (da)	1986-07-02	Fremgangsmaade til fremstilling af proteiner og polypeptider
DK62589D0 (da)	1989-02-10	Kloning og ekspression af human vaekstfaktor
DK182986D0 (da)	1986-04-21	5-pyrimidincarboxamider og behandling af leukaemi og tumorer dermed
DK381886A (da)	1987-02-13	Medicinsk praeparat og fremgangsmaade til dets fremstilling
DK2086A (da)	1986-07-06	Protraheret virkende sterilt vandigt praeparat af et peptid eller protein, dets fremstilling og anvendelse
DK50387D0 (da)	1987-01-30	Rekombinant-humant interleukin-2-praeparat og frem-gangsmaade til dets fremstilling
DK261485A (da)	1985-06-11	Kosmetiske praeparater og fremgangsmaade til deres fremstilling
DK368986D0 (da)	1986-08-01	Cardiotoniske heterocyclo(methyl)carbonylthiazoloner og deres fremstilling
EP0256553A3 (en)	1988-08-10	Gene encoding insecticidal protein and production of said protein using said gene
DK340288D0 (da)	1988-06-21	Polypeptidanaloger og fremgangsmaade til fremstilling deraf
DK271085D0 (da)	1985-06-14	N-benzoyl-n'-pyrimidinyloxyphenylurinstofforbindelser og fremgangsmaade til fremstilling af samme
DK467984A (da)	1985-03-30	4-alkylmethylendioxy-2-1(h)-quinazolinoner og fremgangsmaade til fremstilling deraf
DK356486D0 (da)	1986-07-25	Apparat og fremgangsmaade til vaadbehandling af tekstiler
ZA844207B (en)	1985-01-30	Preparation of human igf and egf via recombinant dna technology
DK128091D0 (da)	1991-06-28	Kloning og fremstilling af polypeptidanaloger af humant fibronektin og anvendelse af saadanne polypeptidanaloger
DK28885D0 (da)	1985-01-22	Hoejkoncentreret vandig human gamma-interferonoploesning sam t fremgangsmaade til fremstilling deraf