DK2767596T3 - Fremgangsmåde til forøgelse af udbytte i fremstillingen af lactose (III) - Google Patents
Fremgangsmåde til forøgelse af udbytte i fremstillingen af lactose (III) Download PDFInfo
- Publication number
- DK2767596T3 DK2767596T3 DK13155557.5T DK13155557T DK2767596T3 DK 2767596 T3 DK2767596 T3 DK 2767596T3 DK 13155557 T DK13155557 T DK 13155557T DK 2767596 T3 DK2767596 T3 DK 2767596T3
- Authority
- DK
- Denmark
- Prior art keywords
- lactose
- solution
- mother liquor
- temperature
- alpha
- Prior art date
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- 239000008101 lactose Substances 0.000 title claims description 71
- 238000000034 method Methods 0.000 title claims description 35
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- 235000013365 dairy product Nutrition 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 150000002402 hexoses Chemical class 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 150000002584 ketoses Chemical class 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000008141 laxative Substances 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 150000002972 pentoses Chemical class 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 150000003641 trioses Chemical class 0.000 description 1
- 238000005292 vacuum distillation Methods 0.000 description 1
- 238000007738 vacuum evaporation Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
- C13K5/00—Lactose
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Claims (13)
1. Fremgangsmåde til forbedring af udbyttet under fremstillingen af krystallinsk alfa-lactose, hvor (a) en vandig lactoseopløsning justeres til en temperatur på mellem ca. 62 : og 67°C, (b) opløsningen nedkøles derefter til mellem ca. 20 og 30°C, (c) opløsningen holdes ved denne temperatur i en periode på fra 0 til 5 timer, (d) opløsningen opvarmes efterfølgende til mellem ca. 30 og 45°C, i (e) opløsningen holdes ved denne temperatur i en periode på fra 0 til 5 timer, (f) opløsningen nedkøles derefter til ca. 10°C, og (g) derefter, adskilles den udfældede første mængde alfa-lactosekrystaller fra moderluden, i (h) en mængde afen kulhydratforbindelse valgt fra gruppen bestående af L-glyceraldehyd, dihydroxyacetone, D-erythrose, D-threose; D-ribose, D- og L-xylulose; D-glucose, D-mannose, D-gulose, D-idose, D-galaktose, D-glucronsyre, D-galacturonsyre, N-acetyl-D-glucosamin, D-glucosamin, D-fructose, L-rhamnose; cellobiose, gentiobiose, isomaltose, isomaltulose, i lactulose, laminaribiose, maltose, maltulose, melibiose, neohesperidose, neotrehalose, nigerose, rutinose, sophorose, saccharose, trehalose eller deres blandinger tilsættes til moderluden sådan at opløselighedsproduktet af restmængden af lactose der stadig er opløseligt overskrides, (i) den anden mængde udfældede alfa-lactosekrystaller adskilles fra i moderluden, tørres, og (j) begge mængder af alfa-lactosekrystaller kombineres.
2. Fremgangsmåden ifølge krav 1, kendetegnet ved at lactoseopløsningen under trin (a) justeres til mellem 63 og 65°C.
3. Fremgangsmåden ifølge kravene 1 og/eller 2, kendetegnet ved at opløsningen under trin (b) nedkøles ved en hastighed på fra ca. 1 til 5°K/time.
4. Fremgangsmåden ifølge mindst ét af kravene 1 til 3, kendetegnet ved at opløsningen under trin (b) nedkøles til mellem 23 og 26°C. i
5. Fremgangsmåden ifølge mindst ét af kravene 1 til 4, kendetegnet ved at opløsningen under trin (c) holdes ved denne temperatur i en periode på ca. 1 til 3 timer.
6. Fremgangsmåden ifølge mindst ét af kravene 1 til 5, kendetegnet ved at opløsningen under trin (d) opvarmes til mellem ca. 32 og 42°C.
7. Fremgangsmåden ifølge mindst ét af kravene 1 til 6, kendetegnet ved at opløsningen under trin (d) holdes ved denne temperatur i en periode på ca. 1 til 3 timer.
8. Fremgangsmåden ifølge mindst ét af kravene 1 til 7, kendetegnet ved at opløsningen under trin (f) nedkøles ved en hastighed på ca. 1 til 5°K/time.
9. Fremgangsmåden ifølge mindst ét af kravene 1 til 8, kendetegnet ved at temperaturprofilen der omfatter trinnene (a) til (g) passeres gennem inden for en periode på ca. 18 til 24 timer.
10. Fremgangsmåden ifølge mindst ét af kravene 1 til 9, kendetegnet ved at alfa-lactosekrystallerne adskilles ved hjælp af en dekanteringsanordning.
11. Fremgangsmåden ifølge mindst ét af kravene 1 til 10, kendetegnet ved at glucose eller en kulhydratfraktion der er rig på glucose anvendes.
12. Fremgangsmåden ifølge mindst ét af kravene 1 til 11, kendetegnet ved at kulhydratforbindelserne tilsættes til moderluden i mængder på op til 5 vægtprocent.
13. Fremgangsmåde til fremstillingen af krystallinsk alfa-lactose, hvor (i) valle underkastes en adskillelsesfremgangsmåde i en hvilken en proteinrig og en lactose-rig fraktion opnås, (ii) den lactose-rige fraktion (eventuelt efter koncentration af hovedstrømmen) underkastes demineralisering i hvilken langsomt i opløselige salte udfældes, (iii) den demineraliserede rest nedkøles, eventuelt efter yderligere koncentration, indtil lactose udfælder i krystallinsk form, (iv) lactosekrystallerne adskilles fra moderluden og dehydreres, kendetegnet ved at i (a) den første moderlud justeres til en temperatur på mellem ca. 62 og 67°C, (b) opløsningen nedkøles derefter til mellem ca. 20 og 30°C, (c) opløsningen holdes ved denne temperatur i en periode på fra 0 til 5 timer, i (d) derefter, genopvarmes opløsningen til mellem ca. 30 og 35°C, (e) opløsningen holdes ved denne temperatur i en periode på fra 0 til 5 timer, (f) derefter nedkøles opløsningen til ca. 10°C og (g) derefter, adskilles de udfældede alfa-lactosekrystaller fra den anden i moderlud, (h) en mængde afen kulhydratforbindelse valgt fra gruppen bestående af L-glyceraldehyd, dihydroxyacetone, D-erythrose, D-threose; D-ribose, D- og L-xylulose; D-glucose, D-mannose, D-gulose, D-idose, D-galaktose, D-glucronsyre, D-galacturonsyre, N-acetyl-D-glucosamin, D-glucosamin, i D-fructose, L-rhamnose; cellobiose, gentiobiose, isomaltose, isomaltulose, lactulose, laminaribiose, maltose, maltulose, melibiose, neohesperidose, neotrehalose, nigerose, rutinose, sophorose, saccharose, trehalose eller deres blanding tilsættes til den anden moderlud sådan at opløselighedsproduktet af restmængden af lactose der stadig er opløseligt i overskrides, (i) den anden mængde udfældede alfa-lactosekrystaller adskilles fra moderluden, tørres, og (j) begge mængder af alfa-lactosekrystaller kombineres.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13155557.5A EP2767596B1 (de) | 2013-02-16 | 2013-02-16 | Verfahren zur Steigerung der Ausbeute bei der Lactoseherstellung (III) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2767596T3 true DK2767596T3 (da) | 2016-05-23 |
Family
ID=47715916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13155557.5T DK2767596T3 (da) | 2013-02-16 | 2013-02-16 | Fremgangsmåde til forøgelse af udbytte i fremstillingen af lactose (III) |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9079932B2 (da) |
| EP (1) | EP2767596B1 (da) |
| CN (1) | CN103993107B (da) |
| DK (1) | DK2767596T3 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2743356T3 (da) * | 2012-12-12 | 2016-06-20 | Dmk Deutsches Milchkontor Gmbh | Fremgangsmåde til forbedring af udbytte ved fremstilling af laktose (I) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4202909A (en) | 1976-11-22 | 1980-05-13 | Patent Technology, Inc. | Treatment of whey |
| GB1575089A (en) | 1976-11-22 | 1980-09-17 | Patent Technology | Process for the treatment of whey and whey permeate and products resulting therefrom |
| US4316749A (en) * | 1980-10-07 | 1982-02-23 | Stauffer Chemical Company | Production of USP quality lactose |
| FR2493869A1 (fr) * | 1980-11-10 | 1982-05-14 | Fives Cail Babcock | Procede de production de lactose cristallise et installation pour la mise en oeuvre de ce procede |
| FI78504C (fi) * | 1987-10-14 | 1989-08-10 | Valio Meijerien | Foerfarande foer tillvaratagande av laktos ur vassla. |
| DE4113836A1 (de) * | 1990-07-04 | 1992-01-09 | Kali Chemie Ag | Verfahren zur suessmolkenpermeataufarbeitung |
| AUPR217700A0 (en) | 2000-12-19 | 2001-01-25 | Food Science Australia | Methods for purification of lactose |
| CN101239996B (zh) * | 2008-01-04 | 2010-10-27 | 华南理工大学 | 一种高剪切力微晶乳糖制备方法 |
| LT2629623T (lt) * | 2010-10-07 | 2018-08-27 | Fonterra Co-Operative Group Limited | Laktozės gamyba |
-
2013
- 2013-02-16 DK DK13155557.5T patent/DK2767596T3/da active
- 2013-02-16 EP EP13155557.5A patent/EP2767596B1/de active Active
-
2014
- 2014-02-11 US US14/177,837 patent/US9079932B2/en active Active
- 2014-02-12 CN CN201410048853.2A patent/CN103993107B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9079932B2 (en) | 2015-07-14 |
| CN103993107A (zh) | 2014-08-20 |
| EP2767596B1 (de) | 2016-02-10 |
| CN103993107B (zh) | 2019-03-01 |
| EP2767596A1 (de) | 2014-08-20 |
| US20140235849A1 (en) | 2014-08-21 |
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