DK27884A - Monoklonale antistofblandinger og anvendelsen deraf til foroeget sensitivitets-immunoassays - Google Patents

Monoklonale antistofblandinger og anvendelsen deraf til foroeget sensitivitets-immunoassays Download PDF

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Publication number
DK27884A
DK27884A DK27884A DK27884A DK27884A DK 27884 A DK27884 A DK 27884A DK 27884 A DK27884 A DK 27884A DK 27884 A DK27884 A DK 27884A DK 27884 A DK27884 A DK 27884A
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DK
Denmark
Prior art keywords
application
monoclonal antibody
increased sensitivity
antibody mixtures
sensitivity immunoassays
Prior art date
Application number
DK27884A
Other languages
English (en)
Other versions
DK27884D0 (da
Inventor
Robert E Canfield
Paul H Ehrlich
William R Moyle
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Publication of DK27884D0 publication Critical patent/DK27884D0/da
Publication of DK27884A publication Critical patent/DK27884A/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/965—Chemistry: molecular biology and microbiology involving idiotype or anti-idiotype antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y10S436/818—Human chorionic gonadotropin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK27884A 1982-05-21 1984-01-20 Monoklonale antistofblandinger og anvendelsen deraf til foroeget sensitivitets-immunoassays DK27884A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/380,959 US4514505A (en) 1982-05-21 1982-05-21 Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
PCT/US1983/000751 WO1983004312A1 (en) 1982-05-21 1983-05-17 Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays

Publications (2)

Publication Number Publication Date
DK27884D0 DK27884D0 (da) 1984-01-20
DK27884A true DK27884A (da) 1984-01-20

Family

ID=23503106

Family Applications (1)

Application Number Title Priority Date Filing Date
DK27884A DK27884A (da) 1982-05-21 1984-01-20 Monoklonale antistofblandinger og anvendelsen deraf til foroeget sensitivitets-immunoassays

Country Status (5)

Country Link
US (1) US4514505A (da)
EP (1) EP0108805A4 (da)
CA (1) CA1222449A (da)
DK (1) DK27884A (da)
WO (1) WO1983004312A1 (da)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792528A (en) * 1982-05-21 1988-12-20 The Trustees Of Columbia University In The City Of New York Methods for obtaining monoclonal antibodies useful in enhanced sensitivity immunoassays
US4851356A (en) * 1983-05-06 1989-07-25 The Trustees Of Columbia University In The City Of New York Immunoassay for human chorionic gonadotropin
US4839275A (en) * 1983-12-01 1989-06-13 The Jewish Hospital Circulating antigens of dirofilaria immitis, monoclonal antibodies specific therefor and methods of preparing such antibodies and detecting such antigens
US4666865A (en) * 1984-01-13 1987-05-19 Centocor, Inc. Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies
US5011771A (en) * 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
GR850899B (da) * 1984-04-12 1985-11-25 Gen Hospital Corp
NO171169C (no) * 1984-04-17 1993-02-03 Teijin Ltd Monoklonale antistoffer eller fragmenter derav, spesifikke for alfa2-plasmininhibitor
EP0232447A1 (en) * 1986-02-13 1987-08-19 Xoma Corporation Lectin immunotoxins
US4590071A (en) * 1984-09-25 1986-05-20 Xoma Corporation Human melanoma specific immunotoxins
US4722889A (en) * 1985-04-02 1988-02-02 Leeco Diagnostics, Inc. Immunoassays using multiple monoclonal antibodies and scavenger antibodies
US5026653A (en) * 1985-04-02 1991-06-25 Leeco Diagnostic, Inc. Scavenger antibody mixture and its use for immunometric assay
US4935339A (en) * 1985-05-07 1990-06-19 Nichols Institute Diagnostics Delayed solid phase immunologic assay
DE3525926A1 (de) * 1985-07-19 1987-01-29 Boehringer Mannheim Gmbh Verfahren und reagenz zur spezifischen bestimmung von pankreas-alpha-amylase
US5284778A (en) * 1985-08-12 1994-02-08 The Trustees Of Columbia University In The City Of New York Sensitive bioassay using monoclonal antibodies which bind to hormone-receptor complexes
EP0243471A4 (en) * 1985-10-22 1989-07-11 Cooper Lipotech Inc SOLID PHASE LIPOSOME IMMUNOANALYSIS SYSTEM.
WO1987006004A1 (en) * 1986-03-26 1987-10-08 Murex Corporation Device and method for determining microbial resistance to antimicrobic agents
JPH07119762B2 (ja) * 1986-04-09 1995-12-20 和光純薬工業株式会社 補体の定量方法
AU7358187A (en) * 1986-04-11 1987-11-09 Murex Corp. Colorimetric ratioing immunoassay
US5223441A (en) 1986-10-09 1993-06-29 Syntex (U.S.A.) Inc. Receptors for immune complexes
US4874693A (en) * 1986-10-10 1989-10-17 Mark Bogart Method for assessing placental dysfunction
DE3885388T2 (de) * 1987-03-17 1994-02-24 Daniel Navot Fruchtbarkeitsvorhersage durch verwendung eines clomiphen-kontrollsatzes.
US5091170A (en) * 1987-03-17 1992-02-25 Daniel Navot Fertility prediction by use of clomiphene challenge test
FR2615622B1 (fr) * 1987-05-19 1994-05-06 Ire Medgenix Sa Dosage plasmatique de monokines
NO884368L (no) * 1987-10-02 1989-04-03 Du Pont Immunanalyse ved anvendelse av igg-innfangelsesantistoff og multippel, monoklonalt antistoffpaavisningssystem.
US4900547A (en) * 1987-10-23 1990-02-13 University Of British Columbia Method to immunize mammals against tumors
US5356817A (en) * 1988-06-09 1994-10-18 Yale University Methods for detecting the onset, progression and regression of gynecologic cancers
US5177014A (en) * 1988-12-05 1993-01-05 Idexx Laboratories, Inc. Monoclonal antibodies to feline-T-lymphotropic lentivirus
US5219725A (en) * 1988-12-05 1993-06-15 Idexx Laboratories Incorporated Monoclonal antibodies to feline-t-lymphotropic lentivirus
DE3929119A1 (de) * 1989-09-01 1991-03-07 Boehringer Mannheim Gmbh Verfahren zum nachweis von analyten
WO1991005876A1 (en) * 1989-10-20 1991-05-02 Children's Biomedical Research Institute Human cytomegalovirus-specific monoclonal antibody cocktail
US5366863A (en) * 1990-04-05 1994-11-22 Hygeia Sciences, Inc. Total gonadotropal alpha peptide chain assay
US5223393A (en) * 1990-06-12 1993-06-29 Microgenics Corporation Detection of analytes having binding sites for at least two binding moieties
US5130232A (en) * 1990-06-12 1992-07-14 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibody immunoassay kit for avian reticuloendotheliosis virus
US6022541A (en) * 1991-10-18 2000-02-08 Beth Israel Deaconess Medical Center Immunological preparation for concurrent specific binding to spatially exposed regions of vascular permeability factor bound in-vivo to a tumor associated blood vessel
EP0751782B1 (en) * 1994-02-18 2006-10-11 Applied Research Systems ARS Holding N.V. Use of a non-neutralizing antibody specific for the beta-subunit of luteinizing hormone for enhancing fertility
US6376170B1 (en) 1994-10-03 2002-04-23 The Scripps Research Institute Ligand capture-directed selection of antibody
US6180340B1 (en) 1997-10-31 2001-01-30 Gen-Probe Incorporated Extended dynamic range assays
US6500627B1 (en) 1998-02-03 2002-12-31 The Trustees Of Columbia University In The City Of New York Methods for predicting pregnancy outcome in a subject by HCG assay
US6927034B2 (en) * 1998-02-03 2005-08-09 The Trustees Of Columbia University In The City Of New York Methods for detecting trophoblast malignancy by HCG assay
US7198954B1 (en) * 1999-02-03 2007-04-03 The Trustees Of Columbia University In The City Of New York Methods for predicting pregnancy outcome in a subject by hCG assay
US6458528B1 (en) 1998-05-15 2002-10-01 Idexx Laboratories, Inc. Diagnosis of feline immunodeficiency virus infection using ENV/GAG polypeptide markers
DE69938242T2 (de) * 1998-07-21 2009-04-09 Boehringer Ingelheim (Canada) Ltd., Laval Regionen des papillomavirus-e1-helikase beteiligt an e1 oligomerisierung
US20070111259A1 (en) * 1999-10-02 2007-05-17 Medarex, Inc. Human antibodies
US7135287B1 (en) 1999-10-02 2006-11-14 Biosite, Inc. Human antibodies
US6680209B1 (en) * 1999-12-06 2004-01-20 Biosite, Incorporated Human antibodies as diagnostic reagents
US20040018577A1 (en) * 2002-07-29 2004-01-29 Emerson Campbell John Lewis Multiple hybrid immunoassay
EP3330385A1 (en) 2009-07-21 2018-06-06 Gen-Probe Incorporated Methods for quantitative detection of nucleic acid sequences over an extended dynamic range
MY151976A (en) * 2009-07-21 2014-07-31 Sekisui Medical Co Ltd Insulin assay
US10088490B2 (en) 2010-08-20 2018-10-02 Siemens Healthcare Diagnostics Inc. Assay for analytes using multiple receptors
WO2012049316A1 (en) 2010-10-15 2012-04-19 Olink Ab Dynamic range methods
CN103308683B (zh) * 2012-03-14 2015-08-26 珀金埃尔默医学诊断产品（上海）有限公司 糖类抗原19-9时间分辨免疫荧光分析法及试剂盒
CN104714015B (zh) * 2014-10-28 2017-05-17 威海纽普生物技术有限公司 心型脂肪酸结合蛋白检测试剂盒及检测方法
CN104730251B (zh) * 2014-11-28 2016-11-23 威海纽普生物技术有限公司 肌钙蛋白i检测试剂盒及检测方法
GB2537604A (en) * 2015-04-15 2016-10-26 Ian Hawkins David A toy
CN111381027B (zh) * 2018-12-29 2023-07-28 深圳市帝迈生物技术有限公司 免疫捕获组合物及其制备方法和应用、免疫检测试剂盒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935074A (en) * 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US4048298A (en) * 1975-02-25 1977-09-13 Rohm And Haas Company Solid phase double-antibody radioimmunoassay procedure
GB1572220A (en) * 1976-10-07 1980-07-30 Mochida Pharm Co Ltd Immunochemical process of measuring physiologically active substances
US4098876A (en) * 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
JPS5359017A (en) * 1976-11-02 1978-05-27 Terumo Corp Fractionation and purification of red blood corpuscle
US4244940A (en) * 1978-09-05 1981-01-13 Bio-Rad Laboratories, Inc. Single-incubation two-site immunoassay
WO1982000364A1 (en) * 1980-07-16 1982-02-04 Jefferis R Methods of immuno-analysis using monoclonal antibodies
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies

Also Published As

Publication number Publication date
US4514505A (en) 1985-04-30
DK27884D0 (da) 1984-01-20
CA1222449A (en) 1987-06-02
EP0108805A4 (en) 1985-04-11
EP0108805A1 (en) 1984-05-23
WO1983004312A1 (en) 1983-12-08

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