DK2809648T3 - Oxygenberigede amino- eller ammonium-holdige sulfonsyrederivater og disses medicinske anvendelse - Google Patents

Oxygenberigede amino- eller ammonium-holdige sulfonsyrederivater og disses medicinske anvendelse Download PDF

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Publication number
DK2809648T3
DK2809648T3 DK12730164.6T DK12730164T DK2809648T3 DK 2809648 T3 DK2809648 T3 DK 2809648T3 DK 12730164 T DK12730164 T DK 12730164T DK 2809648 T3 DK2809648 T3 DK 2809648T3
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DK
Denmark
Prior art keywords
ammonium
oxygen
sulfonic acid
acid derivatives
medical use
Prior art date
Application number
DK12730164.6T
Other languages
English (en)
Inventor
Georg Schlechtingen
Hans-Joachim Knölker
Tim Friedrichson
Gary Jennings
Tobias Braxmeier
Original Assignee
Gri Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gri Bio Inc filed Critical Gri Bio Inc
Application granted granted Critical
Publication of DK2809648T3 publication Critical patent/DK2809648T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK12730164.6T 2011-05-26 2012-05-25 Oxygenberigede amino- eller ammonium-holdige sulfonsyrederivater og disses medicinske anvendelse DK2809648T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11167731 2011-05-26
PCT/EP2012/059810 WO2012160186A1 (en) 2011-05-26 2012-05-25 Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use

Publications (1)

Publication Number Publication Date
DK2809648T3 true DK2809648T3 (da) 2019-06-17

Family

ID=44839732

Family Applications (2)

Application Number Title Priority Date Filing Date
DK19166502.5T DK3597634T3 (da) 2011-05-26 2012-05-25 Oxygenerede, ammoniumholdige sulfonsyrer og medicinsk anvendelse deraf
DK12730164.6T DK2809648T3 (da) 2011-05-26 2012-05-25 Oxygenberigede amino- eller ammonium-holdige sulfonsyrederivater og disses medicinske anvendelse

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK19166502.5T DK3597634T3 (da) 2011-05-26 2012-05-25 Oxygenerede, ammoniumholdige sulfonsyrer og medicinsk anvendelse deraf

Country Status (6)

Country Link
US (4) US9751834B2 (da)
EP (2) EP2809648B1 (da)
CA (1) CA2886676C (da)
DK (2) DK3597634T3 (da)
ES (2) ES2727038T3 (da)
WO (1) WO2012160186A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9751834B2 (en) 2011-05-26 2017-09-05 Gri Bio, Inc. Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
EP2739606B1 (en) 2011-05-26 2016-04-27 Jado Technologies GmbH Hydroxy-substituted amino and ammonium derivatives and their medical use
DK2809318T3 (da) 2011-05-26 2019-07-22 Gri Bio Inc Ammoniumholdige sulfonsyre-, phosphonsyre- og carboxylsyrederivater og disses medicinske anvendelse
BR112013033309B1 (pt) 2011-06-24 2022-07-05 Gri Bio, Inc Uso de tazaroteno e método in vitro para inibição de ativação de células nkt tipo i
CN110734460B (zh) * 2019-10-22 2022-03-29 华南师范大学 一类磺酸-膦酸配体的制备及其用途
CN113548977A (zh) * 2021-07-12 2021-10-26 广州乐信生物科技有限公司 N-甲基-β-丙氨酸衍生物的制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3280179A (en) 1961-03-16 1966-10-18 Textilana Corp Processes for producing acyclic surfactant sulfobetaines
FR1326561A (fr) 1962-03-29 1963-05-10 Oreal Adjuvant pour fixateur de permanente
US3432408A (en) 1966-08-03 1969-03-11 Udylite Corp Chromium plating electrolyte and method for preventing mist therein
US3623990A (en) * 1967-06-26 1971-11-30 Procter & Gamble Liquid detergent composition
GB1471144A (en) * 1973-06-29 1977-04-21 Shell Int Research Manufacture of sulphobetaines
US4085134A (en) 1974-02-15 1978-04-18 Petrolite Corporation Amino-phosphonic-sulfonic acids
GB1541427A (en) * 1976-08-27 1979-02-28 Shell Int Research Preparation of hydroxysulphobetaines
US4259249A (en) * 1979-06-13 1981-03-31 The Procter & Gamble Company Preparation of hydroxyl zwitterionic compounds
US5314917A (en) 1991-03-22 1994-05-24 E. B. Michaels Research Associates, Inc. Method for inactivating enveloped viruses and sperm
US5545667A (en) 1991-04-26 1996-08-13 The Clorox Company Methods for treating neoplasms with betaines
EP0569028A2 (en) 1992-05-07 1993-11-10 Lonza Inc. Shampoos containing polyglyceryl esters
US5658749A (en) 1994-04-05 1997-08-19 Corning Clinical Laboratories, Inc. Method for processing mycobacteria
US6406880B1 (en) * 1997-05-02 2002-06-18 Integrated Research Technology, Llc Betaines as adjuvants to susceptibility testing and antimicrobial therapy
EP1296709A1 (en) 2000-06-21 2003-04-02 Ferring BV Solubilised protein vaccines
EP1646375A2 (en) 2003-06-23 2006-04-19 Neurochem (International) Limited Treatment of protein aggregation disorders
JP2009520730A (ja) 2005-12-23 2009-05-28 ヤド・テヒノロギース・ゲーエムベーハー アレルギー性疾患を治療および予防するための手段および方法
CN101456810A (zh) 2007-12-13 2009-06-17 中国科学院兰州化学物理研究所 一种酯交换反应合成脂肪酸酯的方法
US20110071100A1 (en) 2008-05-05 2011-03-24 Tiltan Pharma Ltd. Sulfobetaines for cancer, obesity, macular degeneration, neurodegenerative diseases
CA2743232C (en) 2008-11-11 2015-12-29 Novartis Ag Crystalline forms of fingolimod hcl
JP2010120998A (ja) 2008-11-18 2010-06-03 Toho Chem Ind Co Ltd 帯電防止剤および帯電防止性熱可塑性樹脂組成物
US9751834B2 (en) 2011-05-26 2017-09-05 Gri Bio, Inc. Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
DK2809318T3 (da) 2011-05-26 2019-07-22 Gri Bio Inc Ammoniumholdige sulfonsyre-, phosphonsyre- og carboxylsyrederivater og disses medicinske anvendelse
EP2739606B1 (en) 2011-05-26 2016-04-27 Jado Technologies GmbH Hydroxy-substituted amino and ammonium derivatives and their medical use

Also Published As

Publication number Publication date
US12528775B2 (en) 2026-01-20
ES2727038T3 (es) 2019-10-11
DK3597634T3 (da) 2025-03-24
EP2809648A1 (en) 2014-12-10
ES3015206T3 (en) 2025-04-30
CA2886676A1 (en) 2012-11-29
US20210114979A1 (en) 2021-04-22
US20230265052A1 (en) 2023-08-24
HK1204602A1 (en) 2015-11-27
US10815195B2 (en) 2020-10-27
WO2012160186A1 (en) 2012-11-29
US9751834B2 (en) 2017-09-05
CA2886676C (en) 2019-03-05
EP3597634A1 (en) 2020-01-22
US11453642B2 (en) 2022-09-27
US20150284320A1 (en) 2015-10-08
US20170369430A1 (en) 2017-12-28
EP2809648B1 (en) 2019-04-03
EP3597634B1 (en) 2025-02-26

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