DK2825558T3 - Kombinationsterapi til behandling af ovariecancer - Google Patents

Kombinationsterapi til behandling af ovariecancer Download PDF

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Publication number
DK2825558T3
DK2825558T3 DK13708435.6T DK13708435T DK2825558T3 DK 2825558 T3 DK2825558 T3 DK 2825558T3 DK 13708435 T DK13708435 T DK 13708435T DK 2825558 T3 DK2825558 T3 DK 2825558T3
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DK
Denmark
Prior art keywords
treatment
ovarian cancer
combination therapy
therapy
ovarian
Prior art date
Application number
DK13708435.6T
Other languages
English (en)
Inventor
Corrado Bernasconi
David Bollag
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47844333&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2825558(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK2825558T3 publication Critical patent/DK2825558T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00—Commerce
    • G06Q30/02—Marketing; Price estimation or determination; Fundraising
    • G06Q30/0241—Advertisements
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q90/00—Systems or methods specially adapted for administrative, commercial, financial, managerial or supervisory purposes, not involving significant data processing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Business, Economics & Management (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Economics (AREA)
  • Theoretical Computer Science (AREA)
  • Finance (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Development Economics (AREA)
  • Strategic Management (AREA)
  • General Physics & Mathematics (AREA)
  • General Business, Economics & Management (AREA)
  • Physics & Mathematics (AREA)
  • Accounting & Taxation (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Marketing (AREA)
  • Entrepreneurship & Innovation (AREA)
  • Game Theory and Decision Science (AREA)
  • Reproductive Health (AREA)
  • Dispersion Chemistry (AREA)
DK13708435.6T 2012-03-13 2013-03-11 Kombinationsterapi til behandling af ovariecancer DK2825558T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261610128P 2012-03-13 2012-03-13
US201261653598P 2012-05-31 2012-05-31
US201261672987P 2012-07-18 2012-07-18
PCT/EP2013/054818 WO2013135602A2 (en) 2012-03-13 2013-03-11 Combination therapy for the treatment of ovarian cancer

Publications (1)

Publication Number Publication Date
DK2825558T3 true DK2825558T3 (da) 2019-07-22

Family

ID=47844333

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13708435.6T DK2825558T3 (da) 2012-03-13 2013-03-11 Kombinationsterapi til behandling af ovariecancer

Country Status (32)

Country Link
US (2) US20150098988A1 (da)
EP (2) EP3553083A1 (da)
JP (2) JP6563197B2 (da)
KR (1) KR102082363B1 (da)
CN (1) CN104334577A (da)
AR (1) AR090313A1 (da)
AU (2) AU2013231410B2 (da)
BR (1) BR112014018964A2 (da)
CA (2) CA2860941C (da)
CO (1) CO7000770A2 (da)
CR (1) CR20140400A (da)
CY (1) CY1121821T1 (da)
DK (1) DK2825558T3 (da)
EA (1) EA201400996A1 (da)
ES (1) ES2736030T3 (da)
HK (1) HK1202122A1 (da)
HR (1) HRP20191248T1 (da)
HU (1) HUE045445T2 (da)
IL (2) IL234174B (da)
LT (1) LT2825558T (da)
MX (1) MX365139B (da)
PE (1) PE20141909A1 (da)
PH (1) PH12014501543A1 (da)
PL (1) PL2825558T3 (da)
PT (1) PT2825558T (da)
RS (1) RS58964B1 (da)
SG (1) SG11201404417PA (da)
SI (1) SI2825558T1 (da)
SM (1) SMT201900389T1 (da)
TW (1) TW201343178A (da)
WO (1) WO2013135602A2 (da)
ZA (1) ZA201404843B (da)

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TWI583699B (zh) 2011-09-23 2017-05-21 安可美德藥物股份有限公司 Ｖｅｇｆ／ｄｌｌ４結合劑類及彼等之用途
PL2825558T3 (pl) 2012-03-13 2019-11-29 Hoffmann La Roche Terapia skojarzona w leczeniu raka jajnika
WO2015200905A2 (en) 2014-06-28 2015-12-30 Oligasis, Llc Dual pdgf/vegf antagonists
US11339213B2 (en) 2015-09-23 2022-05-24 Mereo Biopharma 5, Inc. Methods and compositions for treatment of cancer
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US20200121703A1 (en) * 2017-06-26 2020-04-23 The Cleveland Clinic Foundation Cancer treatment
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CN120695174A (zh) * 2021-07-01 2025-09-26 江苏先声生物制药有限公司 抗人vegf抗体与化药联用在制备治疗卵巢癌的药物中的应用
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Also Published As

Publication number Publication date
SI2825558T1 (sl) 2019-08-30
KR20140138691A (ko) 2014-12-04
EP3553083A1 (en) 2019-10-16
PT2825558T (pt) 2019-07-11
LT2825558T (lt) 2019-08-12
HK1202122A1 (en) 2015-09-18
CA3056813A1 (en) 2013-09-19
WO2013135602A3 (en) 2013-11-07
PE20141909A1 (es) 2014-11-29
CR20140400A (es) 2014-10-07
BR112014018964A2 (pt) 2020-05-12
RS58964B1 (sr) 2019-08-30
PH12014501543A1 (en) 2014-10-08
JP2018193380A (ja) 2018-12-06
CO7000770A2 (es) 2014-07-21
AU2017258927A1 (en) 2017-11-30
HUE045445T2 (hu) 2019-12-30
JP2015511593A (ja) 2015-04-20
US20150098988A1 (en) 2015-04-09
CA2860941C (en) 2019-11-05
AU2013231410A1 (en) 2014-07-17
MX2014010591A (es) 2014-09-18
IL234174B (en) 2019-01-31
CA2860941A1 (en) 2013-09-19
HRP20191248T1 (hr) 2019-10-18
AU2013231410B2 (en) 2017-08-17
EP2825558B1 (en) 2019-05-15
CY1121821T1 (el) 2020-10-14
EP2825558A2 (en) 2015-01-21
US20160289317A1 (en) 2016-10-06
IL263781A (en) 2019-01-31
JP6640288B2 (ja) 2020-02-05
TW201343178A (zh) 2013-11-01
CN104334577A (zh) 2015-02-04
MX365139B (es) 2019-05-24
SG11201404417PA (en) 2014-10-30
KR102082363B9 (ko) 2023-05-02
US11384142B2 (en) 2022-07-12
EA201400996A1 (ru) 2015-03-31
WO2013135602A2 (en) 2013-09-19
SMT201900389T1 (it) 2019-09-09
BR112014018964A8 (pt) 2017-07-11
PL2825558T3 (pl) 2019-11-29
KR102082363B1 (ko) 2020-02-27
ZA201404843B (en) 2015-08-26
AR090313A1 (es) 2014-11-05
ES2736030T3 (es) 2019-12-23
JP6563197B2 (ja) 2019-08-21

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