DK2828292T3 - Jcv-neutraliserende antistoffer - Google Patents

Jcv-neutraliserende antistoffer

Info

Publication number
DK2828292T3
DK2828292T3 DK13763643.7T DK13763643T DK2828292T3 DK 2828292 T3 DK2828292 T3 DK 2828292T3 DK 13763643 T DK13763643 T DK 13763643T DK 2828292 T3 DK2828292 T3 DK 2828292T3
Authority
DK
Denmark
Prior art keywords
jcv
neutralizing antibodies
neutralizing
antibodies
Prior art date
Application number
DK13763643.7T
Other languages
English (en)
Inventor
Kenneth Simon
Thomas Cameron
Mia Rushe
George Campbell Kaynor
Justin Caravella
Original Assignee
Biogen Ma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Ma Inc filed Critical Biogen Ma Inc
Application granted granted Critical
Publication of DK2828292T3 publication Critical patent/DK2828292T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081DNA viruses
    • C07K16/084Papillomaviridae (F); Polyomaviridae (F), e.g. SV40, BK virus or JC virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK13763643.7T 2012-03-20 2013-03-15 Jcv-neutraliserende antistoffer DK2828292T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261613249P 2012-03-20 2012-03-20
PCT/US2013/031853 WO2013142300A2 (en) 2012-03-20 2013-03-15 Jcv neutralizing antibodies

Publications (1)

Publication Number Publication Date
DK2828292T3 true DK2828292T3 (da) 2019-01-02

Family

ID=49223445

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13763643.7T DK2828292T3 (da) 2012-03-20 2013-03-15 Jcv-neutraliserende antistoffer

Country Status (6)

Country Link
US (1) US9567391B2 (da)
EP (1) EP2828292B1 (da)
CA (1) CA2867910C (da)
DK (1) DK2828292T3 (da)
ES (1) ES2706173T3 (da)
WO (1) WO2013142300A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2828284T3 (da) 2012-03-20 2019-06-11 Biogen Ma Inc Jcv-neutraliserende antistoffer
ITTO20120570A1 (it) * 2012-06-27 2013-12-28 Pomona Ricerca Srl Anticorpo monoclonale diretto contro il virus jc
CN104936980B (zh) 2012-12-31 2019-06-07 生物控股有限公司 用于治疗和预防多瘤病毒相关的疾病的重组人抗体
WO2015095770A1 (en) * 2013-12-20 2015-06-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Immunogenic jc polyomavirus compositions and methods of use
US9862760B2 (en) 2015-09-16 2018-01-09 Novartis Ag Polyomavirus neutralizing antibodies
CA3083363A1 (en) * 2017-12-01 2019-06-06 Novartis Ag Polyomavirus neutralizing antibodies
WO2020119793A1 (en) * 2018-12-14 2020-06-18 Wuxi Biologics (Shanghai) Co., Ltd. Humanized antibodies against ox40, method for preparing the same, and use thereof
US12410238B2 (en) 2019-06-19 2025-09-09 Icahn School Of Medicine At Mount Sinai Monoclonal antibodies against JC virus
KR20230004725A (ko) * 2020-04-22 2023-01-06 아케소 바이오파마, 인크. 항-cd73 항체 및 이의 용도

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2322560B1 (en) 2005-03-10 2013-09-04 Morphotek, Inc. Anti-mesothelin antibodies
HUE039865T2 (hu) * 2005-12-20 2019-02-28 Sbi Biotech Co Ltd Anti-ILT7 antitest
US7655417B2 (en) 2006-05-31 2010-02-02 Hanwha Chemical Corporation VCAM-1 specific monoclonal antibody
US7910702B2 (en) 2006-07-28 2011-03-22 The Governors Of The University Of Alberta Recombinant antibodies to sclerotinia antigens
SI2308514T1 (sl) 2007-03-23 2013-09-30 To-Bbb Holding B.V. Konjugati za prenos zdravila preko krvno-moĹľganske pregrade
CN101990439A (zh) * 2007-07-06 2011-03-23 特鲁比昂药品公司 具有置于c末端的特异性结合结构域的结合肽
ES2687259T5 (es) 2008-06-25 2022-10-14 Novartis Ag Anticuerpos estables y solubles que inhiben TNF
WO2010090757A1 (en) * 2009-02-05 2010-08-12 Biogen Idec Ma Inc. Methods for the detection of jc polyoma virus
WO2010129959A1 (en) 2009-05-08 2010-11-11 Government Of The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for the prevention and treatment of lupus nephritis using anti-dsdna germline antibodies
EP2316481A1 (en) 2009-10-30 2011-05-04 Biomay Ag Pharmaceutical composition for the treatment and prevention of a rhinovirus infection
DK2828284T3 (da) 2012-03-20 2019-06-11 Biogen Ma Inc Jcv-neutraliserende antistoffer

Also Published As

Publication number Publication date
EP2828292A2 (en) 2015-01-28
ES2706173T3 (es) 2019-03-27
WO2013142300A3 (en) 2013-11-14
EP2828292A4 (en) 2016-03-30
WO2013142300A2 (en) 2013-09-26
CA2867910A1 (en) 2013-09-26
CA2867910C (en) 2023-09-26
US9567391B2 (en) 2017-02-14
EP2828292B1 (en) 2018-10-31
US20150056188A1 (en) 2015-02-26

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