DK282887A - Humane granulocyt-makrofag-kolonistimulationsfaktor-lignende polypeptider og fremgangsmaader til fremstilling deraf i hoeje udbytter i mikrobielle celler - Google Patents

Humane granulocyt-makrofag-kolonistimulationsfaktor-lignende polypeptider og fremgangsmaader til fremstilling deraf i hoeje udbytter i mikrobielle celler

Info

Publication number
DK282887A
DK282887A DK282887A DK282887A DK282887A DK 282887 A DK282887 A DK 282887A DK 282887 A DK282887 A DK 282887A DK 282887 A DK282887 A DK 282887A DK 282887 A DK282887 A DK 282887A
Authority
DK
Denmark
Prior art keywords
macrophag
polypeptides
procedures
production
high yield
Prior art date
Application number
DK282887A
Other languages
English (en)
Other versions
DK282887D0 (da
Inventor
John Delamarter
Joachim F Ernst
Original Assignee
Biogen Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Nv filed Critical Biogen Nv
Publication of DK282887D0 publication Critical patent/DK282887D0/da
Publication of DK282887A publication Critical patent/DK282887A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK282887A 1985-10-03 1987-06-02 Humane granulocyt-makrofag-kolonistimulationsfaktor-lignende polypeptider og fremgangsmaader til fremstilling deraf i hoeje udbytter i mikrobielle celler DK282887A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78341485A 1985-10-03 1985-10-03
PCT/US1986/002106 WO1987002060A1 (en) 1985-10-03 1986-10-03 Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells

Publications (2)

Publication Number Publication Date
DK282887D0 DK282887D0 (da) 1987-06-02
DK282887A true DK282887A (da) 1987-07-30

Family

ID=25129176

Family Applications (1)

Application Number Title Priority Date Filing Date
DK282887A DK282887A (da) 1985-10-03 1987-06-02 Humane granulocyt-makrofag-kolonistimulationsfaktor-lignende polypeptider og fremgangsmaader til fremstilling deraf i hoeje udbytter i mikrobielle celler

Country Status (5)

Country Link
EP (1) EP0238655A4 (da)
JP (1) JPS63502795A (da)
AU (2) AU606585B2 (da)
DK (1) DK282887A (da)
WO (1) WO1987002060A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
US5242811A (en) * 1985-03-26 1993-09-07 Biogen, Inc. Production of human somatomedin C
DE3712985A1 (de) * 1987-04-16 1988-11-03 Hoechst Ag Bifunktionelle proteine
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
EP0276846A3 (en) * 1987-01-29 1989-07-26 Zymogenetics, Inc. Colony-stimulating factor derivatives
JPS6420097A (en) * 1987-03-02 1989-01-24 Sumitomo Chemical Co Human granulocyte-macrophage colony stimulating factor
WO1988010310A1 (en) * 1987-06-25 1988-12-29 Immunex Corporation Bovine granulocyte-macrophage colony stimulating factor
CA1335717C (en) * 1987-07-17 1995-05-30 Takashi Yokota Human granulocyte-macrophage colony stimulating factor and muteins thereof
EP0391892A4 (en) * 1987-10-30 1990-11-28 Immunex Corporation Nonglycosylated analogs of human colony stimulating factors
GB2212159B (en) * 1987-11-13 1992-01-22 British Bio Technology Synthetic gene for human granulocyte/macrophage colony stimulating factor.
WO1989010403A1 (en) * 1988-04-21 1989-11-02 Medvet Science Pty. Ltd. Human gm-csf variants
WO1989010158A1 (en) * 1988-04-27 1989-11-02 Immunomedics, Inc. Improved radiotherapy
US5178855A (en) * 1989-01-30 1993-01-12 Schering Corporation Treatment of luekocyte dysfunction with GM-CSF
EP0791061A4 (en) * 1994-03-04 1998-07-15 Ludwig Inst Cancer Res TARGET GENE BREAKING ANIMALS
RU2144083C1 (ru) * 1998-03-13 2000-01-10 Государственный научный центр вирусологии и биотехнологии "Вектор" Способ промышленного получения рекомбинантного гранулоцит-макрофаг-колониестимулирующего фактора человека
US6979442B1 (en) 1998-08-17 2005-12-27 Pfizer Inc. Stabilized protein compositions
EP2042196B1 (en) 2001-10-10 2016-07-13 ratiopharm GmbH Remodelling and glycoconjugation of Granulocyte Colony Stimulating Factor (G-CSF)
MX2011000859A (es) 2008-07-23 2011-02-24 Ambrx Inc Polipeptidos g-csf bovinos modificados y sus usos.
TWI480288B (zh) 2010-09-23 2015-04-11 Lilly Co Eli 牛顆粒細胞群落刺激因子及其變體之調配物
JP6698854B2 (ja) * 2016-09-16 2020-05-27 キッセイ薬品工業株式会社 遺伝子改変細胞及びその作製方法
CN119842769A (zh) * 2025-01-21 2025-04-18 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 重组猫巨噬细胞集落刺激因子的原核表达质粒及其构建方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6030654B2 (ja) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 ヒトコロニ−刺激因子の製造方法
NZ212645A (en) * 1984-07-06 1990-02-26 Sandoz Ltd Method for producing primate granulocyte-macrophage colony stimulating factor (gm-csf)
ZA856108B (en) * 1984-10-29 1986-10-29 Immunex Corp Cloning of human granulocyte-macrophage colony simulating factor gene
EP0202300B1 (en) * 1984-11-20 1992-11-11 Schering Biotech Corporation Cdna clones coding for polypeptides exhibiting human granulocyte macrophage and eosinophil cellular growth factor activity
US5391485A (en) * 1985-08-06 1995-02-21 Immunex Corporation DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung

Also Published As

Publication number Publication date
AU630516B2 (en) 1992-10-29
AU6578190A (en) 1991-01-10
WO1987002060A1 (en) 1987-04-09
AU6549386A (en) 1987-04-24
AU606585B2 (en) 1991-02-14
JPS63502795A (ja) 1988-10-20
DK282887D0 (da) 1987-06-02
EP0238655A1 (en) 1987-09-30
EP0238655A4 (en) 1989-09-11

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