DK287980A - Fremgangsmaade til fremstilling af anthracyclinglycosider - Google Patents

Fremgangsmaade til fremstilling af anthracyclinglycosider

Info

Publication number: DK287980A
Authority: DK; Denmark
Prior art keywords: compounds; hydrogen atom; anthracycling; lycosides; procedure
Prior art date: 1979-07-04

Application number

DK287980A

Other languages

English (en)

Other versions

DK152053B (da

DK152053C (da

Inventor

G Cassinelli

S Forenza

M C Ripamonti

D Ruggieri

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-07-04

Filing date

1980-07-03

Publication date

1981-01-05

1980-07-03 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1981-01-05 Publication of DK287980A publication Critical patent/DK287980A/da

1988-01-25 Publication of DK152053B publication Critical patent/DK152053B/da

1988-08-29 Application granted granted Critical

1988-08-29 Publication of DK152053C publication Critical patent/DK152053C/da

Links

229930190071 lycoside Natural products 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 2
230000001225 therapeutic effect Effects 0.000 abstract 2
230000000259 anti-tumor effect Effects 0.000 abstract 1
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK287980A 1979-07-04 1980-07-03 Analogifremgangsmaade til fremstilling af anthracyclinglycosider eller deres farmaceutiske acceptable syreadditionssalte DK152053C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB7923225		1979-07-04
GB7923225		1979-07-04

Publications (3)

Publication Number	Publication Date
DK287980A true DK287980A (da)	1981-01-05
DK152053B DK152053B (da)	1988-01-25
DK152053C DK152053C (da)	1988-08-29

Family

ID=10506282

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK287980A DK152053C (da)	1979-07-04	1980-07-03	Analogifremgangsmaade til fremstilling af anthracyclinglycosider eller deres farmaceutiske acceptable syreadditionssalte

Country Status (9)

Country	Link
US (1)	US4322412A (da)
EP (1)	EP0022515B1 (da)
JP (1)	JPS5610200A (da)
AT (1)	ATE4387T1 (da)
CA (1)	CA1154012A (da)
DE (1)	DE3064485D1 (da)
DK (1)	DK152053C (da)
IT (1)	IT1131887B (da)
SU (1)	SU1017173A3 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS56156300A (en) *	1980-04-26	1981-12-02	Microbial Chem Res Found	Novel preparative method of anthracyclin derivative
NL8300150A (nl) *	1982-01-26	1983-08-16	Erba Farmitalia	Daunorubicine en doxorubicine-analoga, hun bereiding en toepassing.
GB8708927D0 (en) *	1987-04-14	1987-05-20	Erba Farmitalia	Chiral synthesis of anthracyclines
US5177091A (en) *	1990-12-06	1993-01-05	Ciba-Geigy Corporation	Use of carbazones as novel active ingredients in medicaments
AU658175B2 (en) *	1991-04-12	1995-04-06	Novartis Ag	Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients
PL380561A1 (pl) *	2006-09-05	2008-03-17	Szeja Wiesław Prochem Szeja	Sposób otrzymywania pochodnych antracyklin
US8357785B2 (en) *	2008-01-08	2013-01-22	Solux Corporation	Method of aralkylation of 4′-hydroxyl group of anthracylins
CN104151376B (zh) *	2014-06-23	2017-02-08	天津药物研究院新药评价有限公司	一种抗肿瘤药物及其合成方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4039663A (en) *	1975-03-19	1977-08-02	Societa' Farmaceutici Italia S.P.A.	Daunomycins, process for their uses and intermediates
GB1550879A (en) *	1976-12-22	1979-08-22	Farmaceutici Italia	Antitumour glycosides
BE864336A (fr) *	1977-05-05	1978-06-16	Farmaceutici Italia	Nouveaux derives d'anthracyclines
GB1573037A (en) *	1977-05-05	1980-08-13	Farmaceutici Italia	Anthracyclines
NL7900869A (nl) *	1978-02-09	1979-08-13	Erba Farmitalia	Anthracyclinenantibiotica.
BE883759A (fr) *	1979-06-16	1980-10-01	Erba Farmitalia	Glycosides d'anthracycline

1980
- 1980-07-01 AT AT80103743T patent/ATE4387T1/de not_active IP Right Cessation
- 1980-07-01 DE DE8080103743T patent/DE3064485D1/de not_active Expired
- 1980-07-01 EP EP80103743A patent/EP0022515B1/en not_active Expired
- 1980-07-02 IT IT23190/80A patent/IT1131887B/it active
- 1980-07-03 DK DK287980A patent/DK152053C/da not_active IP Right Cessation
- 1980-07-03 CA CA000355353A patent/CA1154012A/en not_active Expired
- 1980-07-03 JP JP9006180A patent/JPS5610200A/ja active Granted
- 1980-07-03 SU SU802943002A patent/SU1017173A3/ru active
- 1980-07-14 US US06/168,157 patent/US4322412A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE3064485D1 (en)	1983-09-08
DK152053B (da)	1988-01-25
EP0022515A1 (en)	1981-01-21
JPS5610200A (en)	1981-02-02
EP0022515B1 (en)	1983-08-03
IT1131887B (it)	1986-06-25
US4322412A (en)	1982-03-30
CA1154012A (en)	1983-09-20
DK152053C (da)	1988-08-29
ATE4387T1 (de)	1983-08-15
JPS6328076B2 (da)	1988-06-07
SU1017173A3 (ru)	1983-05-07
IT8023190A0 (it)	1980-07-02

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Legal Events

Date	Code	Title	Description
1991-03-25	PBP	Patent lapsed