DK2882441T3 - Behandling af immunrelaterede og inflammatoriske sygdomme - Google Patents

Behandling af immunrelaterede og inflammatoriske sygdomme Download PDF

Info

Publication number
DK2882441T3
DK2882441T3 DK13752753.7T DK13752753T DK2882441T3 DK 2882441 T3 DK2882441 T3 DK 2882441T3 DK 13752753 T DK13752753 T DK 13752753T DK 2882441 T3 DK2882441 T3 DK 2882441T3
Authority
DK
Denmark
Prior art keywords
immunrated
treatment
inflammatory diseases
inflammatory
diseases
Prior art date
Application number
DK13752753.7T
Other languages
English (en)
Inventor
Peter H Schafer
Anita Gandhi
Rajesh Chopra
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Application granted granted Critical
Publication of DK2882441T3 publication Critical patent/DK2882441T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK13752753.7T 2012-08-09 2013-08-08 Behandling af immunrelaterede og inflammatoriske sygdomme DK2882441T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261681491P 2012-08-09 2012-08-09
US201261722718P 2012-11-05 2012-11-05
PCT/US2013/054051 WO2014025958A2 (en) 2012-08-09 2013-08-08 Treatment of immune-related and inflammatory diseases

Publications (1)

Publication Number Publication Date
DK2882441T3 true DK2882441T3 (da) 2020-05-25

Family

ID=49029213

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13752753.7T DK2882441T3 (da) 2012-08-09 2013-08-08 Behandling af immunrelaterede og inflammatoriske sygdomme

Country Status (30)

Country Link
US (2) US10919883B2 (da)
EP (2) EP3741372A1 (da)
JP (2) JP6250671B2 (da)
KR (3) KR102118559B1 (da)
CN (4) CN114939119A (da)
AU (1) AU2013299625B2 (da)
BR (1) BR112015002272A2 (da)
CA (2) CA2881113C (da)
CY (1) CY1123106T1 (da)
DK (1) DK2882441T3 (da)
EA (1) EA029085B1 (da)
ES (1) ES2800026T3 (da)
HR (1) HRP20200836T1 (da)
HU (1) HUE049569T2 (da)
IL (1) IL237070B (da)
LT (1) LT2882441T (da)
MX (1) MX373328B (da)
NI (1) NI201500013A (da)
NZ (2) NZ727295A (da)
PH (1) PH12015500276A1 (da)
PL (1) PL2882441T3 (da)
PT (1) PT2882441T (da)
RS (1) RS60416B1 (da)
SG (1) SG11201500983RA (da)
SI (1) SI2882441T1 (da)
SM (1) SMT202000333T1 (da)
TW (1) TWI641371B (da)
UA (1) UA116992C2 (da)
WO (1) WO2014025958A2 (da)
ZA (1) ZA201500466B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2536706B1 (en) 2010-02-11 2017-06-14 Celgene Corporation Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
AU2012236655B2 (en) 2011-03-28 2016-09-22 Deuterx, Llc, 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds
US20150038511A1 (en) 2012-08-09 2015-02-05 Celgene Corporation Treatment of immune-related and inflammatory diseases
CA2935495C (en) 2013-01-14 2021-04-20 Deuterx, Llc 3-(5-substituted-4-oxoquinazolin-3(4h)-yl)-3-deutero-piperidine-2,6-dione derivatives
US9695145B2 (en) 2013-01-22 2017-07-04 Celgene Corporation Processes for the preparation of isotopologues of 3-(4-((4- morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and pharmaceutically acceptable salts thereof
EP2968334A4 (en) 2013-03-14 2016-08-03 Deuterx Llc 3- (SUBSTITIERTES-4-OXO-quinazolin-3 (4H) -yl) -3-deutero-PIPERIDINE-2,6-DIONE DERIVATIVES
US10245266B2 (en) * 2014-05-19 2019-04-02 Celgene Corporation 3-(4-((4-morpholinomethyl-benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione for the treatment of systemic lupus erythematosus
WO2015179279A1 (en) * 2014-05-19 2015-11-26 Celgene Corporation Treatment of immune-related and inflammatory diseases
US9809603B1 (en) 2015-08-18 2017-11-07 Deuterx, Llc Deuterium-enriched isoindolinonyl-piperidinonyl conjugates and oxoquinazolin-3(4H)-yl-piperidinonyl conjugates and methods of treating medical disorders using same
HRP20210694T1 (hr) 2016-07-15 2021-09-17 Acceleron Pharma, Inc. Pripravci koji sadrže actriia polipeptide za uporabu za liječenje plućne hipertenzije
BR112020023756A2 (pt) * 2018-05-23 2021-02-09 Celgene Corporation tratamento de mieloma múltiplo e uso de biomarcadores para 4-(4-(4-(((2-(2,6-dioxopiperidin-3-il)-1-oxoisoindolin-4-il)oxi)metil)benzil)piperazin-1-il)-3-fluorobenzonitrila
AU2019351811B2 (en) 2018-10-01 2025-01-02 Celgene Corporation Combination therapy for the treatment of cancer
US11939390B2 (en) * 2019-01-28 2024-03-26 Sanofi-Aventis U.S. Llc Methods of treating multiple myeloma
US11609233B2 (en) 2019-03-28 2023-03-21 Alentic Microscience Inc. Indicator-based analysis of a sample
US10684278B1 (en) * 2019-03-28 2020-06-16 Alentic Microscience Inc. Bead-based analysis of a sample
US11255850B2 (en) 2019-03-28 2022-02-22 Alentic Microscience Inc. Bead-based analysis of a sample
US11719700B2 (en) 2019-03-28 2023-08-08 Alentic Microscience Inc. Upconversion for microscopy
JP2022527133A (ja) 2019-04-12 2022-05-30 リップタイド バイオサイエンス インコーポレイテッド マクロファージの活性を調節する方法
WO2021108303A1 (en) * 2019-11-25 2021-06-03 PHPrecisionMed, LLC Pharmaceutical compositions for the treatment of pulmonary hypertension
EP4142769A4 (en) 2020-04-28 2024-05-15 Acceleron Pharma Inc. ACTRII PROTEINS AND USE IN THE TREATMENT OF POSTCAPILLARY PULMONARY HYPERTENSION
AR123650A1 (es) * 2020-10-02 2022-12-28 Celgene Corp Métodos para el tratamiento del lupus eritematoso sistémico y el uso de biomarcadores como un predictor de sensibilidad clínica a terapias
WO2023097111A2 (en) * 2021-11-29 2023-06-01 Riptide Bioscience, Inc. Methods and compositions for treating calcinosis associated conditions
WO2024064646A1 (en) 2022-09-20 2024-03-28 Celgene Corporation Salts and solid forms of (s)- or racemic 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and methods of using the same
WO2025233646A2 (en) * 2024-05-09 2025-11-13 Debreceni Egyetem Detection of celiac disease-specific autoantibodies

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
HU196714B (en) 1984-10-04 1989-01-30 Monsanto Co Process for producing non-aqueous composition comprising somatotropin
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
PH30995A (en) 1989-07-07 1997-12-23 Novartis Inc Sustained release formulations of water soluble peptides.
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5733566A (en) 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
TW333456B (en) 1992-12-07 1998-06-11 Takeda Pharm Ind Co Ltd A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
US6087324A (en) 1993-06-24 2000-07-11 Takeda Chemical Industries, Ltd. Sustained-release preparation
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
AU6242096A (en) 1995-06-27 1997-01-30 Takeda Chemical Industries Ltd. Method of producing sustained-release preparation
TW448055B (en) 1995-09-04 2001-08-01 Takeda Chemical Industries Ltd Method of production of sustained-release preparation
JP2909418B2 (ja) 1995-09-18 1999-06-23 株式会社資生堂 薬物の遅延放出型マイクロスフイア
US5980945A (en) 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
US6264970B1 (en) 1996-06-26 2001-07-24 Takeda Chemical Industries, Ltd. Sustained-release preparation
US5635517B1 (en) 1996-07-24 1999-06-29 Celgene Corp Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
US6419961B1 (en) 1996-08-29 2002-07-16 Takeda Chemical Industries, Ltd. Sustained release microcapsules of a bioactive substance and a biodegradable polymer
CA2217134A1 (en) 1996-10-09 1998-04-09 Sumitomo Pharmaceuticals Co., Ltd. Sustained release formulation
DE69730093T2 (de) 1996-10-31 2006-07-20 Takeda Pharmaceutical Co. Ltd. Zubereitung mit verzögerter Freisetzung
WO1998027980A2 (en) 1996-12-20 1998-07-02 Takeda Chemical Industries, Ltd. Method of producing a sustained-release preparation
US5891474A (en) 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
EP1064277B1 (en) 1998-03-16 2005-06-15 Celgene Corporation 2-(2,6-dioxopiperidin-3-yl)isoindoline derivatives, their preparation and their use as inhibitors of inflammatory cytokines
US6613358B2 (en) 1998-03-18 2003-09-02 Theodore W. Randolph Sustained-release composition including amorphous polymer
KR19990085365A (ko) 1998-05-16 1999-12-06 허영섭 지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6984522B2 (en) * 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
CA2418835A1 (en) 2000-10-16 2002-04-25 Phylos, Inc. Protein scaffolds for antibody mimics and other binding proteins
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
DK1390535T3 (da) 2001-04-26 2010-12-06 Amgen Mountain View Inc Kombinatoriske biblioteker af monomer-domæner
GB0120441D0 (en) 2001-08-22 2001-10-17 Novartis Forschungsstiftung Model of autoimmune disease and methods for identifying anti autoimmune disease disorders
US7173032B2 (en) 2001-09-21 2007-02-06 Reddy Us Therapeutics, Inc. Methods and compositions of novel triazine compounds
EP1824796A4 (en) 2004-11-16 2010-02-17 Avidia Res Inst PROTEIN SKELETONS AND USES THEREOF
AU2007249805B2 (en) * 2006-05-12 2013-01-10 University Of Miami Biomarkers for detection and diagnosis of head and neck squamous cell carcinoma
US20080045485A1 (en) 2006-08-17 2008-02-21 Peter Muir Methods of diagnosing synovial disease in a mammal by detecting bacterial DNA in synovial tissues from dogs with inflammatory knee arthritis and degenerative anterior cruciate ligament rupture
SG177221A1 (en) * 2006-12-15 2012-01-30 Abbott Lab Novel oxadiazole compounds
KR101791757B1 (ko) 2007-03-20 2017-10-30 셀진 코포레이션 4'-o-치환된 아이소인돌린 유도체 및 이를 포함하는 조성물 및 이의 사용 방법
WO2008119170A1 (en) 2007-03-30 2008-10-09 Chu Sainte Justine Method of determining risk of scoliosis
JP5442185B2 (ja) 2007-04-24 2014-03-12 日本メナード化粧品株式会社 感作性物質評価方法
WO2009124064A1 (en) 2008-03-31 2009-10-08 Boston Medical Center Corporation Predictive marker for topoisomerase i inhibitors
EP2274617A4 (en) 2008-04-10 2011-11-09 Massachusetts Inst Technology METHOD OF DETECTING AND USING MEDIUM-TREATMENT AID ON CANCER STEM CELLS
WO2011109440A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings Biomarkers for theranostics
HUE029289T2 (en) * 2008-12-05 2017-02-28 Abbvie Inc Sulfonamide derivatives as Bcl-2 selective apoptosis inducers for the treatment of cancer and immune diseases
KR101787768B1 (ko) 2009-04-18 2017-10-18 제넨테크, 인크. 항-cd40 항체를 사용한 치료에 대한 b-세포 림프종의 반응성 평가를 위한 방법
EP2536706B1 (en) * 2010-02-11 2017-06-14 Celgene Corporation Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
JP2013540995A (ja) 2010-08-18 2013-11-07 カリス ライフ サイエンシズ ルクセンブルク ホールディングス エス.アー.エール.エル. 疾患に対する循環バイオマーカー
WO2012115885A1 (en) * 2011-02-22 2012-08-30 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers
EP2721179A4 (en) * 2011-06-16 2014-10-01 Caris Life Sciences Luxembourg Holdings S A R L BIOMARKER COMPOSITIONS AND METHOD THEREFOR
ES2872967T3 (es) 2012-06-29 2021-11-03 Celgene Corp Métodos para determinar la eficacia de fármacos usando IKZF3 (AIOLOS)
US20150038511A1 (en) 2012-08-09 2015-02-05 Celgene Corporation Treatment of immune-related and inflammatory diseases
US20140343058A1 (en) 2012-08-09 2014-11-20 Celgene Corporation Treatment of systemic lupus erythematosus
UA117141C2 (uk) 2013-10-08 2018-06-25 Селджин Корпорейшн Склади (s)-3-(4-((4-(морфолінометил)бензил)оксі)-1-оксоізоіндолін-2-іл)піперидин-2,6-діону
US10245266B2 (en) 2014-05-19 2019-04-02 Celgene Corporation 3-(4-((4-morpholinomethyl-benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione for the treatment of systemic lupus erythematosus

Also Published As

Publication number Publication date
KR102118559B1 (ko) 2020-06-03
RS60416B1 (sr) 2020-07-31
EA201590342A1 (ru) 2015-07-30
ZA201500466B (en) 2016-06-29
JP6595565B2 (ja) 2019-10-23
NZ628077A (en) 2017-04-28
NI201500013A (es) 2019-05-10
JP2018070623A (ja) 2018-05-10
EP3741372A1 (en) 2020-11-25
JP2015527349A (ja) 2015-09-17
CY1123106T1 (el) 2021-10-29
US20140045844A1 (en) 2014-02-13
PH12015500276A1 (en) 2015-04-27
PL2882441T3 (pl) 2020-09-21
CA2881113A1 (en) 2014-02-13
CA3092279A1 (en) 2014-02-13
MX2015001686A (es) 2015-04-10
PT2882441T (pt) 2020-06-29
WO2014025958A2 (en) 2014-02-13
WO2014025958A3 (en) 2014-04-17
MX373328B (es) 2020-05-04
AU2013299625A1 (en) 2015-02-12
EA029085B1 (ru) 2018-02-28
JP6250671B2 (ja) 2017-12-20
IL237070B (en) 2019-06-30
KR102266509B1 (ko) 2021-06-16
CN115068484A (zh) 2022-09-20
AU2013299625B2 (en) 2018-02-01
NZ727295A (en) 2018-06-29
UA116992C2 (uk) 2018-06-11
KR20210073616A (ko) 2021-06-18
ES2800026T3 (es) 2020-12-23
EP2882441B1 (en) 2020-04-29
HK1211474A1 (en) 2016-05-27
SMT202000333T1 (it) 2020-07-08
KR20150039848A (ko) 2015-04-13
KR20200058606A (ko) 2020-05-27
TW201408298A (zh) 2014-03-01
BR112015002272A2 (pt) 2017-07-04
EP2882441A2 (en) 2015-06-17
CN104703605A (zh) 2015-06-10
CA3092279C (en) 2023-08-08
IL237070A0 (en) 2015-03-31
SI2882441T1 (sl) 2020-08-31
SG11201500983RA (en) 2015-04-29
US20210340132A1 (en) 2021-11-04
CN114939119A (zh) 2022-08-26
CA2881113C (en) 2020-10-27
US10919883B2 (en) 2021-02-16
HRP20200836T1 (hr) 2020-08-07
CN108938642A (zh) 2018-12-07
HUE049569T2 (hu) 2020-09-28
TWI641371B (zh) 2018-11-21
LT2882441T (lt) 2020-07-27

Similar Documents

Publication Publication Date Title
DK2882441T3 (da) Behandling af immunrelaterede og inflammatoriske sygdomme
DK2882496T3 (da) Behandling og diagnosticering af melanom
LT2885010T (lt) Tautopatijos gydymo būdai
DK2806892T3 (da) Kombineret terapeutisk anvendelse af antistoffer og endoglycosidaser
DK2968208T3 (da) Behandling af kataplexi
DK2846809T3 (da) Behandling af myelosuppression
DK2970101T4 (da) Pro-drugs af fumarater og deres anvendelse i behandling af forskellige sygdomme
DK2723347T3 (da) Forebyggelse og behandling af inflammationstilstande
DK3444342T3 (da) Fremgangsmåder og sammensætninger til behandlingen af lysosomale aflejringssygdomme
DK3626270T3 (da) Behandling af kardiovaskulære sygdomme
DK2919796T3 (da) Brug af akkermansia til behandling af stofskiftesygdomme
DK2981255T3 (da) Terapeutiske anvendelser af empagliflozin
DK2892912T3 (da) C17-alkandiyl og alkenediylderivater af oleanolsyre og fremgangsmåder til anvendelse deraf
DK2688557T3 (da) Fremgangsmåder og sammensætninger til behandling af forstyrelse af opmærksomhed
DK3238707T3 (da) Sammensætninger og fremgangsmåder til behandling af intestinal hyperpermeabilitet
PL2830654T3 (pl) Sposoby i kompozycje do leczenia zapalenia
LT3007726T (lt) Tautopatijos gydymo būdai
DK3060908T3 (da) Diagnosticering og behandling af autoimmune sygdomme
DK2800575T3 (da) Behandling af subarachnoidalblødning og iskæmi
DK2661274T3 (da) Sammensætninger og fremgangsmåder med aloepolysaccharider
PL3400958T3 (pl) Kompozycje i metody leczenia celiakii
DK2854910T3 (da) Ceramidniveauer i behandling og forebyggelse af infektioner
IL234606B (en) Novel methods and composition for treatment of disease
DK2673363T3 (da) Behandling af angiogenesesygdomme
DK2892556T3 (da) Sammensætninger og fremgangsmåder til behandling af sygdomme