DK2895867T3 - Hidtil ukendte d-enantiomer peptider afledt af d3 og anvendelse deraf - Google Patents

Hidtil ukendte d-enantiomer peptider afledt af d3 og anvendelse deraf Download PDF

Info

Publication number
DK2895867T3
DK2895867T3 DK13776426.2T DK13776426T DK2895867T3 DK 2895867 T3 DK2895867 T3 DK 2895867T3 DK 13776426 T DK13776426 T DK 13776426T DK 2895867 T3 DK2895867 T3 DK 2895867T3
Authority
DK
Denmark
Prior art keywords
enantiomes
unknown
peptides derived
peptides
derived
Prior art date
Application number
DK13776426.2T
Other languages
English (en)
Inventor
Dieter Willbold
Oleksander Brener
Susanne Aileen Funke
Luitgard Nagel-Steger
Antonia Nicole Klein
Dirk Bartnik
Original Assignee
Forschungszentrum Juelich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich Gmbh filed Critical Forschungszentrum Juelich Gmbh
Application granted granted Critical
Publication of DK2895867T3 publication Critical patent/DK2895867T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4709Amyloid plaque core protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2410/00Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
DK13776426.2T 2012-09-14 2013-09-13 Hidtil ukendte d-enantiomer peptider afledt af d3 og anvendelse deraf DK2895867T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102012108598.6A DE102012108598A1 (de) 2012-09-14 2012-09-14 Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung
PCT/EP2013/068992 WO2014041115A2 (de) 2012-09-14 2013-09-13 Neue, von d3 abgeleitete d-enantiomere peptide und deren verwendung

Publications (1)

Publication Number Publication Date
DK2895867T3 true DK2895867T3 (da) 2020-02-03

Family

ID=49354628

Family Applications (2)

Application Number Title Priority Date Filing Date
DK13776426.2T DK2895867T3 (da) 2012-09-14 2013-09-13 Hidtil ukendte d-enantiomer peptider afledt af d3 og anvendelse deraf
DK17172220.0T DK3346273T5 (da) 2012-09-14 2013-09-13 Hidtil ukendte d-enantiomer peptider afledt af d3 og anvendelse deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK17172220.0T DK3346273T5 (da) 2012-09-14 2013-09-13 Hidtil ukendte d-enantiomer peptider afledt af d3 og anvendelse deraf

Country Status (9)

Country Link
US (3) US20150307552A1 (da)
EP (2) EP2895867B1 (da)
JP (2) JP6345670B2 (da)
CN (2) CN107556375A (da)
DE (1) DE102012108598A1 (da)
DK (2) DK2895867T3 (da)
ES (2) ES2938773T3 (da)
PL (1) PL3346273T3 (da)
WO (1) WO2014041115A2 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012108598A1 (de) * 2012-09-14 2014-04-10 Forschungszentrum Jülich GmbH Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung
DE102015003503A1 (de) * 2015-03-20 2016-09-22 Forschungszentrum Jülich GmbH Spezifisch Amyloid-Beta bindende Peptide und deren Verwendung für die Therapie und Diagnose der Alzheimerschen Demenz
DE102015003676A1 (de) 2015-03-20 2016-09-22 Forschungszentrum Jülich GmbH Fachbereich Patente Spezifisch A-Beta Spezies bindende Peptide für die Therapie und/oder die Diagnose der Alzheimerschen Demenz
DE102016125645A1 (de) * 2016-12-23 2018-06-28 Forschungszentrum Jülich GmbH D-enantiomere Peptide zur Therapie von chronischem und neuropathischem Schmerz
RU2020114744A (ru) * 2017-10-02 2021-11-09 Седарс-Синаи Медикал Сентер Способы и композиции для эффективной доставки через множество биобарьеров
DE102021121435A1 (de) * 2021-08-18 2023-02-23 Priavoid Gmbh Aß-BINDENDE SUBSTANZEN

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60126980T2 (de) * 2000-11-27 2007-11-08 Praecis Pharmaceuticals Inc., Waltham Therapeutische agentien und methoden ihrer verwendung zur behandlung von amyloidogenen erkrankungen
WO2002081515A1 (fr) * 2001-04-03 2002-10-17 Kyowa Hakko Kogyo Co., Ltd. Proteine de liaison de facteur de croissance de type insuline
DE10117281A1 (de) 2001-04-06 2002-10-24 Inst Molekulare Biotechnologie Peptid zur Diagnose und Therapie der Alzheimer-Demenz
US20050158306A1 (en) * 2004-01-16 2005-07-21 Halikas James A. Treatment for neuro-degenerative disease by a blood cleansing system using monoclonal antibodies
AT500483B1 (de) * 2004-07-13 2006-01-15 Mattner Frank Dr Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung
US20070092508A1 (en) * 2005-10-21 2007-04-26 Recombiant Technologies, Llc Detoxification depot for Alzheimer's disease
WO2010062570A2 (en) * 2008-10-27 2010-06-03 Recombinant Technologies Llc COMPOSITIONS COMPRISING CAPTURE PEPTIDES FOR A β-AMYLOID PEPTIDE
DE102008037564A1 (de) * 2008-11-19 2010-05-20 Forschungszentrum Jülich GmbH Zusammensetzung zur Herstellung von anti-Amyloid beta-Peptid-Antikörpern mit D-Peptiden
DE102010017130B4 (de) 2010-05-28 2018-11-29 Forschungszentrum Jülich GmbH Hybrid-Verbindung, deren Verwendung und Verfahren zu deren Herstellung
DE102012108598A1 (de) * 2012-09-14 2014-04-10 Forschungszentrum Jülich GmbH Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung
CN108926749A (zh) * 2012-04-05 2018-12-04 于利希研究中心有限公司 处理血液、血液产品和器官的方法
JP6434903B2 (ja) * 2012-04-05 2018-12-05 フォルシュングスツェントルム ユーリッヒ ゲゼルシャフト ミット ベシュレンクテル ハフツングForschungszentrum Juelich GmbH 多価アミロイドβに結合するD−ペプチド含有ポリマー及びその使用

Also Published As

Publication number Publication date
JP6345670B2 (ja) 2018-06-20
PL3346273T3 (pl) 2023-04-11
EP3346273A8 (de) 2018-08-29
EP3346273B1 (de) 2023-01-04
JP2018141008A (ja) 2018-09-13
EP2895867A2 (de) 2015-07-22
JP2015531348A (ja) 2015-11-02
DK3346273T3 (da) 2023-02-27
DE102012108598A1 (de) 2014-04-10
JP6611858B2 (ja) 2019-11-27
ES2768264T3 (es) 2020-06-22
EP3346273A1 (de) 2018-07-11
US20150307552A1 (en) 2015-10-29
CN104704371A (zh) 2015-06-10
EP2895867B1 (de) 2019-10-23
WO2014041115A3 (de) 2014-06-26
CN104704371B (zh) 2017-11-07
US20170313744A1 (en) 2017-11-02
CN107556375A (zh) 2018-01-09
DK3346273T5 (da) 2024-09-30
ES2938773T3 (es) 2023-04-14
US20190085030A1 (en) 2019-03-21
US10889618B2 (en) 2021-01-12
WO2014041115A2 (de) 2014-03-20
US10167318B2 (en) 2019-01-01

Similar Documents

Publication Publication Date Title
DK2866825T3 (da) Anvendelse af langstidsvirkende glp-1-peptider
DK2914291T3 (da) Anti-komplement-c1s-antistoffer og anvendelser deraf
DK2895100T3 (da) Digital bideskinne
EP2920562A4 (en) PORTABLE SPECTROMETER
EP2661839A4 (en) SAFE PORTABLE ELEMENT
DK3195844T3 (da) Ganghjælpeindretning
DK2968443T3 (da) Hepcidinanaloger og anvendelser deraf
DK2920197T3 (da) Prolinlåste sammenhæftede peptider og anvendelser deraf
DK3725778T3 (da) Formuleringer af enzalutamid
EP2896039A4 (en) IMPROVING THE PHONETIC DEBATE
DK3055811T3 (da) Bærbar sportstidtagningsmærkeenhed
DK2970954T3 (da) Modifikation af polypeptider
IL236874B (en) Anti-kit antibodies and uses thereof
DK3363805T3 (da) Fremgangsmåder til syntese af sphingomyeliner og dihydrosphingomyeliner
EP4221456C0 (en) PORTABLE BRIDGE DEVICE
EP3719681C0 (de) Benutzer-identifikation
CL2014002180A1 (es) Peptidos antomicrobianos
EP2855506A4 (en) PEPTIDE AND USE THEREOF
HRP20180452T1 (hr) Peptidi
DK2943460T3 (da) 6-chlor-3-(phenyl-d5)-inden-1-on og anvendelse deraf
IL245924B (en) Topk peptides and vaccines including the same
DK2895867T3 (da) Hidtil ukendte d-enantiomer peptider afledt af d3 og anvendelse deraf
EP2914218A4 (en) SPIRAL SUPPORT
IL236690B (en) Ube2t peptides and vaccines containing the same
DK2702756T3 (da) Bærbart kamera