DK2900254T3 - Alfa-1-mikroglobulin til anvendelse ved behandlingen af mitokondrie-relaterede sygdomme - Google Patents
Alfa-1-mikroglobulin til anvendelse ved behandlingen af mitokondrie-relaterede sygdomme Download PDFInfo
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- DK2900254T3 DK2900254T3 DK13759995.7T DK13759995T DK2900254T3 DK 2900254 T3 DK2900254 T3 DK 2900254T3 DK 13759995 T DK13759995 T DK 13759995T DK 2900254 T3 DK2900254 T3 DK 2900254T3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Claims (8)
1. Alfa-1 -mikroglobulin til anvendelse ved behandlingen af en mitokondriesygdom eller til anvendelse ved reparation, retablering eller opretholdelse af mitokondriefunktion.
2. Alfa-1 -mikroglobulin til anvendelse ifølge krav 1, hvor mitokondriesygdommen er valgt fra den følgende liste: • Alpers sygdom (progressiv Infantil poliodystrofl) • Barth-syndrom (letal infantil kardlomyopati) • Beta-oxIdationsdefekter • Kardlomyopati • Carnitin-acyl-carnitin-mangel • Carnitin-mangel • Kreatin-mangelsyndromer (cerebrale kreatin-mangelsyndromer (CCDS) omfatter: guanidinoacetat-methyltransferase-mangel (GAMT-mangel), L-arginin:glycin-amidinotransferase-mangel (AGAT-mangel) og SLC6A8-rela-teret kreatintransportør-mangel (SLC6A8-mangel) • Coenzym Q1 O-mangel • Kompleks l-mangel (NADH-dehydrogenase (NADH-CoQ-reduktase)-mangel) • Kompleks Il-mangel (succinatdehydrogenase-mangel) • Kompleks IIl-mangel (ubiquinon-cytochrom c-oxidoreduktase-mangel) • Kompleks IV-mangel /COX-mangel (cytochrom c-oxidase-mangel skyldes en defekt i kompleks IV i den respiratoriske kæde) • Kompleks V-mangel (ATP-synthase-mangel) • COX-mangel • CPEO (kronisk progressivt eksternt oftalmoplegi-syndrom) • CPT l-mangel • CPT Il-mangel • Friedrelchs ataksi (FRDA eller FA) • Encefalomyopati • Glutarsyreuri type II • KSS (Kearns-Sayre-syndrom) • Laktisk acidose • LOAD (langkædet acyl-CoA-dehydrogenase-mangel) • LCHAD • Leighs sygdom eller syndrom (subakut nekrotiserende encefalomyelopati) • LHON (Lebers arvelige optiske neuropati) • Lufts sygdom • MCAD (mellemlang kæde-acyl-CoA-dehydrogenase-mangel) • MELAS (mitokondrie-encefalomyopati, laktisk acidose og slagtilfældelignende episoder) • MERRF (myoklonisk epilepsi og ragged-red fiber-sygdom) • MIRAS (mitokondrie-recessivt ataksi-syndrom) • Mitokondrie-cytopati • Mitokondrie-DNA-depletion • Mitokondrie-encefalopati omfatter: encefalomyopati, encefalomyelopati • Mitokondrie-myopati • MNGIE (myoneurogastrointestinal lidelse og encefalopati) • NARP (neuropati, ataksi og retinis pigmentosa) • Pearson-syndrom • Pyruvatcarboxylase-mangel • Pyruvatdehydrogenase-mangel • POLG-mutationer • Respiratorisk kæde-mangler • SCAD (kortkædet acyl-CoA-dehydrogenase-mangel) . SCHAD • VLCAD (meget langkædet acyl-CoA-dehydrogenase-mangel)
3. Alfa-1 -mikroglobulin til anvendelse ifølge ethvert af de foregående krav ved behandlingen eller forebyggelsen af respiratorisk kæde-sygdomme.
4. Alfa-1-mikroglobulin til anvendelse ifølge krav 3, hvor de respiratorisk kæde-sygdomme omfatter kompleks I, II, III, IV eller V-mangler.
5. Alfa-1 -mikroglobulin til anvendelse ifølge ethvert af de foregående krav ved behandlingen eller forebyggelsen af mitokondrie-dysfunktioner hos børn eller unge voksne.
6. Alfa-1 -mikroglobulin til anvendelse ifølge ethvert af de foregående krav ved behandlingen eller forebyggelsen af Alpers sygdom, Barth-syndrom, Friedreichs ataksi, KSS, Leighs sygdom eller syndrom, LHON, MELAS, MERRF, MIRAS og NARP.
7. Alfa-1 -mikroglobulin til anvendelse ifølge ethvert af de foregående krav ved behandlingen eller forebyggelsen af mitokondrie-dysfunktioner hos kvinder.
8. Alfa-1 -mikroglobulin til anvendelse ifølge ethvert af de foregående krav ved behandlingen eller forebyggelsen af beskadigelse eller dysfunktion af retina eller øjensygdomme associeret med mitokondrie-defekt(er) eller -dysfunktion(er).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201270538 | 2012-09-05 | ||
| DKPA201270557 | 2012-09-12 | ||
| PCT/EP2013/068270 WO2014037390A1 (en) | 2012-09-05 | 2013-09-04 | Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2900254T3 true DK2900254T3 (da) | 2016-08-29 |
Family
ID=49162118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13759995.7T DK2900254T3 (da) | 2012-09-05 | 2013-09-04 | Alfa-1-mikroglobulin til anvendelse ved behandlingen af mitokondrie-relaterede sygdomme |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10226507B2 (da) |
| EP (1) | EP2900254B1 (da) |
| JP (2) | JP2015533790A (da) |
| KR (1) | KR20150047510A (da) |
| CN (1) | CN104661673A (da) |
| AU (1) | AU2013311714C1 (da) |
| BR (1) | BR112015003957A2 (da) |
| CA (1) | CA2881321A1 (da) |
| DK (1) | DK2900254T3 (da) |
| EA (1) | EA028963B1 (da) |
| ES (1) | ES2599034T3 (da) |
| HR (1) | HRP20161364T1 (da) |
| HU (1) | HUE030559T2 (da) |
| IN (1) | IN2015DN00515A (da) |
| MX (1) | MX357656B (da) |
| NZ (1) | NZ629621A (da) |
| PL (1) | PL2900254T3 (da) |
| PT (1) | PT2900254T (da) |
| SG (1) | SG11201500669SA (da) |
| WO (1) | WO2014037390A1 (da) |
| ZA (1) | ZA201500547B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016204360A (ja) * | 2015-02-25 | 2016-12-08 | エー１エム ファーマ エービーＡ１Ｍ Ｐｈａｒｍａ ＡＢ | 放射性核種療法における腎臓の保護に用いるためのアルファ−１−ミクログロブリン |
| EP3419647A1 (en) * | 2016-02-25 | 2019-01-02 | A1M Pharma AB | Alpha-1-microglobulin for use in the protection of kidneys in connection with use of contrast media |
| CA3017836A1 (en) * | 2016-03-18 | 2017-09-21 | A1M Pharma Ab | Novel alpha-1-microglobulin derived proteins and their use |
| GB2566516A (en) | 2017-09-15 | 2019-03-20 | Univ Oxford Innovation Ltd | Electrochemical recognition and quantification of cytochrome c oxidase expression in bacteria |
| CN109867717A (zh) * | 2019-04-01 | 2019-06-11 | 山西瑞亚力生物技术有限公司 | 一种血浆中α1微球蛋白的提取方法 |
| CN110452980B (zh) * | 2019-09-23 | 2023-07-28 | 武汉儿童医院 | 一种线粒体脑肌病诊断试剂盒及应用 |
| US20220362293A1 (en) * | 2019-09-25 | 2022-11-17 | Cytegen Corp. | Treatment of Mitochondrial Deficits and Age-Related Diseases Using Blood Products |
| CN115575646B (zh) * | 2022-11-21 | 2023-04-28 | 四川大学华西医院 | 一种代谢标志物组在制备预测癫痫发作的试剂盒中的用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007513884A (ja) * | 2003-11-26 | 2007-05-31 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 高められた心血管性リスクのインジケーターとしての尿細管性蛋白尿 |
| ES2426069T3 (es) * | 2007-02-12 | 2013-10-21 | A1M Pharma Ab | Diagnóstico de preeclampsia |
| PT2300614E (pt) * | 2008-02-04 | 2016-03-02 | Yissum Res Dev Co | Métodos e composições para tratamento de distúrbios mitocondriais |
| EP2313106B1 (en) * | 2008-07-18 | 2016-03-30 | A1M Pharma AB | Medical use of the radical scavenger and antioxidant alpha-1-microglobulin |
-
2013
- 2013-09-04 MX MX2015002604A patent/MX357656B/es active IP Right Grant
- 2013-09-04 ES ES13759995.7T patent/ES2599034T3/es active Active
- 2013-09-04 US US14/423,260 patent/US10226507B2/en not_active Expired - Fee Related
- 2013-09-04 AU AU2013311714A patent/AU2013311714C1/en not_active Ceased
- 2013-09-04 CN CN201380043567.0A patent/CN104661673A/zh active Pending
- 2013-09-04 PL PL13759995T patent/PL2900254T3/pl unknown
- 2013-09-04 WO PCT/EP2013/068270 patent/WO2014037390A1/en not_active Ceased
- 2013-09-04 KR KR1020157005748A patent/KR20150047510A/ko not_active Ceased
- 2013-09-04 EP EP13759995.7A patent/EP2900254B1/en not_active Not-in-force
- 2013-09-04 BR BR112015003957A patent/BR112015003957A2/pt not_active Application Discontinuation
- 2013-09-04 CA CA2881321A patent/CA2881321A1/en not_active Abandoned
- 2013-09-04 HR HRP20161364TT patent/HRP20161364T1/hr unknown
- 2013-09-04 HU HUE13759995A patent/HUE030559T2/en unknown
- 2013-09-04 NZ NZ629621A patent/NZ629621A/en not_active IP Right Cessation
- 2013-09-04 PT PT137599957T patent/PT2900254T/pt unknown
- 2013-09-04 EA EA201590503A patent/EA028963B1/ru not_active IP Right Cessation
- 2013-09-04 IN IN515DEN2015 patent/IN2015DN00515A/en unknown
- 2013-09-04 SG SG11201500669SA patent/SG11201500669SA/en unknown
- 2013-09-04 DK DK13759995.7T patent/DK2900254T3/da active
- 2013-09-04 JP JP2015530375A patent/JP2015533790A/ja active Pending
-
2015
- 2015-01-23 ZA ZA2015/00547A patent/ZA201500547B/en unknown
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2018
- 2018-08-24 JP JP2018157394A patent/JP2018203756A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20150258171A1 (en) | 2015-09-17 |
| JP2015533790A (ja) | 2015-11-26 |
| JP2018203756A (ja) | 2018-12-27 |
| BR112015003957A2 (pt) | 2017-08-08 |
| IN2015DN00515A (da) | 2015-06-26 |
| EA028963B1 (ru) | 2018-01-31 |
| HRP20161364T1 (hr) | 2016-12-16 |
| WO2014037390A1 (en) | 2014-03-13 |
| EP2900254B1 (en) | 2016-08-03 |
| AU2013311714C1 (en) | 2018-01-25 |
| MX2015002604A (es) | 2015-06-10 |
| KR20150047510A (ko) | 2015-05-04 |
| MX357656B (es) | 2018-07-18 |
| HK1210585A1 (en) | 2016-04-29 |
| NZ629621A (en) | 2015-09-25 |
| SG11201500669SA (en) | 2015-02-27 |
| ZA201500547B (en) | 2017-09-27 |
| AU2013311714B2 (en) | 2017-10-12 |
| ES2599034T3 (es) | 2017-01-31 |
| HUE030559T2 (en) | 2017-05-29 |
| US10226507B2 (en) | 2019-03-12 |
| AU2013311714A1 (en) | 2015-03-12 |
| EP2900254A1 (en) | 2015-08-05 |
| CN104661673A (zh) | 2015-05-27 |
| EA201590503A1 (ru) | 2015-06-30 |
| CA2881321A1 (en) | 2014-03-13 |
| PT2900254T (pt) | 2016-10-18 |
| PL2900254T3 (pl) | 2017-02-28 |
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