DK2900263T3 - Monoklonale antistoffer mod vækst- og differentieringsfaktor 15 (gdf-15) - Google Patents

Monoklonale antistoffer mod vækst- og differentieringsfaktor 15 (gdf-15) Download PDF

Info

Publication number: DK2900263T3
Authority: DK; Denmark
Prior art keywords: gdf; monoclonal antibodies; antibodies against; against growth; differential factor
Prior art date: 2012-09-26

Application number

DK13776433.8T

Other languages

English (en)

Inventor

Jörg Wischhusen

Thomas Müller

Stefan Saremba

Markus Junker

Original Assignee

Univ Wuerzburg J Maximilians

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-09-26

Filing date

2013-09-26

Publication date

2019-07-29

2013-09-26 Application filed by Univ Wuerzburg J Maximilians filed Critical Univ Wuerzburg J Maximilians

2019-07-29 Application granted granted Critical

2019-07-29 Publication of DK2900263T3 publication Critical patent/DK2900263T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Oncology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Mycology (AREA)

DK13776433.8T 2012-09-26 2013-09-26 Monoklonale antistoffer mod vækst- og differentieringsfaktor 15 (gdf-15) DK2900263T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP12186185		2012-09-26
PCT/EP2013/070127 WO2014049087A1 (en)	2012-09-26	2013-09-26	Monoclonal antibodies to growth and differentiation factor 15 (gdf-15)

Publications (1)

Publication Number	Publication Date
DK2900263T3 true DK2900263T3 (da)	2019-07-29

Family

ID=46888333

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK13776433.8T DK2900263T3 (da)	2012-09-26	2013-09-26	Monoklonale antistoffer mod vækst- og differentieringsfaktor 15 (gdf-15)

Country Status (23)

Country	Link
US (5)	US20150239968A1 (da)
EP (2)	EP2900263B1 (da)
JP (4)	JP2015532271A (da)
KR (1)	KR101838786B1 (da)
CN (1)	CN104853775B (da)
AU (2)	AU2013322628B2 (da)
CA (1)	CA2886207C (da)
CY (1)	CY1121832T1 (da)
DK (1)	DK2900263T3 (da)
ES (1)	ES2742287T3 (da)
HR (1)	HRP20191326T1 (da)
HU (1)	HUE044363T2 (da)
IL (2)	IL237828B (da)
LT (1)	LT2900263T (da)
NZ (1)	NZ706189A (da)
PL (1)	PL2900263T3 (da)
PT (1)	PT2900263T (da)
RS (1)	RS59045B1 (da)
SG (1)	SG11201502279YA (da)
SI (1)	SI2900263T1 (da)
SM (1)	SMT201900457T1 (da)
TR (1)	TR201910744T4 (da)
WO (1)	WO2014049087A1 (da)

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GB2524553C (en) *	2014-03-26	2017-07-19	Julius-Maximilians-Universitãt Würzburg	Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and uses thereof for treating cancer cachexia
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KR20230107309A (ko)	2020-11-10	2023-07-14	카탈임 게엠베하	항-gdf15 항체 및 암 치료용 투여 용법
CN112698042A (zh) *	2020-12-17	2021-04-23	北京赛诺浦生物技术有限公司	检测人生长分化因子-15的荧光免疫层析试纸条及其制备方法和应用
US20240182585A1 (en)	2021-03-31	2024-06-06	Cambridge Enterprise Limited	Therapeutic inhibitors of gdf15 signalling
CN113252905A (zh) *	2021-05-12	2021-08-13	北京赛诺浦生物技术有限公司	人生长分化因子-15磁微粒化学发光检测试剂盒及其应用
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2013
- 2013-09-26 RS RS20190923A patent/RS59045B1/sr unknown
- 2013-09-26 HR HRP20191326 patent/HRP20191326T1/hr unknown
- 2013-09-26 PL PL13776433T patent/PL2900263T3/pl unknown
- 2013-09-26 ES ES13776433T patent/ES2742287T3/es active Active
- 2013-09-26 EP EP13776433.8A patent/EP2900263B1/en active Active
- 2013-09-26 AU AU2013322628A patent/AU2013322628B2/en active Active
- 2013-09-26 CN CN201380061148.XA patent/CN104853775B/zh active Active
- 2013-09-26 SG SG11201502279YA patent/SG11201502279YA/en unknown
- 2013-09-26 LT LTEP13776433.8T patent/LT2900263T/lt unknown
- 2013-09-26 SM SM20190457T patent/SMT201900457T1/it unknown
- 2013-09-26 EP EP19177843.0A patent/EP3590537A1/en active Pending
- 2013-09-26 US US14/431,281 patent/US20150239968A1/en not_active Abandoned
- 2013-09-26 JP JP2015533588A patent/JP2015532271A/ja active Pending
- 2013-09-26 WO PCT/EP2013/070127 patent/WO2014049087A1/en not_active Ceased
- 2013-09-26 HU HUE13776433 patent/HUE044363T2/hu unknown
- 2013-09-26 NZ NZ706189A patent/NZ706189A/en unknown
- 2013-09-26 PT PT13776433T patent/PT2900263T/pt unknown
- 2013-09-26 SI SI201331512T patent/SI2900263T1/sl unknown
- 2013-09-26 TR TR2019/10744T patent/TR201910744T4/tr unknown
- 2013-09-26 KR KR1020157010334A patent/KR101838786B1/ko active Active
- 2013-09-26 DK DK13776433.8T patent/DK2900263T3/da active
- 2013-09-26 CA CA2886207A patent/CA2886207C/en active Active
2015
- 2015-03-19 IL IL237828A patent/IL237828B/en active IP Right Grant
2017
- 2017-05-26 AU AU2017203523A patent/AU2017203523B2/en active Active
- 2017-07-31 JP JP2017147489A patent/JP6670275B2/ja active Active
2018
- 2018-03-12 US US15/918,841 patent/US10781251B2/en active Active
2019
- 2019-07-24 CY CY20191100787T patent/CY1121832T1/el unknown
- 2019-10-24 JP JP2019193124A patent/JP7270522B2/ja active Active
2020
- 2020-08-11 US US16/990,929 patent/US11891436B2/en active Active
- 2020-09-16 IL IL277392A patent/IL277392A/en unknown
2021
- 2021-08-11 JP JP2021131153A patent/JP2022017219A/ja active Pending
2023
- 2023-12-21 US US18/392,926 patent/US20240239882A1/en active Pending
2025
- 2025-09-24 US US19/338,643 patent/US20260116961A1/en active Pending

Also Published As

Publication number	Publication date
CA2886207C (en)	2021-01-05
US20210054060A1 (en)	2021-02-25
JP6670275B2 (ja)	2020-03-18
EP3590537A1 (en)	2020-01-08
US20150239968A1 (en)	2015-08-27
IL237828B (en)	2020-10-29
SG11201502279YA (en)	2015-04-29
EP2900263A1 (en)	2015-08-05
HUE044363T2 (hu)	2019-10-28
JP2015532271A (ja)	2015-11-09
CA2886207A1 (en)	2014-04-03
AU2013322628B2 (en)	2017-03-02
US20180305447A1 (en)	2018-10-25
CN104853775A (zh)	2015-08-19
BR112015006829A2 (pt)	2017-11-21
US11891436B2 (en)	2024-02-06
CY1121832T1 (el)	2020-07-31
US20260116961A1 (en)	2026-04-30
HK1210950A1 (en)	2016-05-13
AU2017203523A1 (en)	2017-06-15
JP2018019690A (ja)	2018-02-08
PL2900263T3 (pl)	2019-10-31
JP7270522B2 (ja)	2023-05-10
RS59045B1 (sr)	2019-08-30
SI2900263T1 (sl)	2019-09-30
ES2742287T3 (es)	2020-02-13
WO2014049087A1 (en)	2014-04-03
JP2022017219A (ja)	2022-01-25
AU2013322628A1 (en)	2015-04-09
HRP20191326T1 (hr)	2019-11-01
IL277392A (en)	2020-11-30
JP2020043855A (ja)	2020-03-26
IL237828A0 (en)	2015-05-31
US20240239882A1 (en)	2024-07-18
TR201910744T4 (tr)	2019-08-21
SMT201900457T1 (it)	2019-11-13
CN104853775B (zh)	2023-10-20
US10781251B2 (en)	2020-09-22
NZ706189A (en)	2016-09-30
EP2900263B1 (en)	2019-06-05
PT2900263T (pt)	2019-07-29
LT2900263T (lt)	2019-10-10
KR20150082229A (ko)	2015-07-15
AU2017203523B2 (en)	2019-02-07
KR101838786B1 (ko)	2018-03-15

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