DK2916954T3 - CIRCUIT BASED OPTION ELECTRONIC PINCETS - Google Patents
CIRCUIT BASED OPTION ELECTRONIC PINCETS Download PDFInfo
- Publication number
- DK2916954T3 DK2916954T3 DK13853719.6T DK13853719T DK2916954T3 DK 2916954 T3 DK2916954 T3 DK 2916954T3 DK 13853719 T DK13853719 T DK 13853719T DK 2916954 T3 DK2916954 T3 DK 2916954T3
- Authority
- DK
- Denmark
- Prior art keywords
- electrode
- light
- dep
- state
- switching
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/02—Separators
- B03C5/022—Non-uniform field separators
- B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0424—Dielectrophoretic forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Electrochemistry (AREA)
- Molecular Biology (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Engineering & Computer Science (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Mechanical Light Control Or Optical Switches (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Electronic Switches (AREA)
- Photometry And Measurement Of Optical Pulse Characteristics (AREA)
- Light Receiving Elements (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Solid State Image Pick-Up Elements (AREA)
- Switches Operated By Changes In Physical Conditions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261724168P | 2012-11-08 | 2012-11-08 | |
| US14/051,004 US9403172B2 (en) | 2012-11-08 | 2013-10-10 | Circuit based optoelectronic tweezers |
| PCT/US2013/067564 WO2014074367A1 (en) | 2012-11-08 | 2013-10-30 | Circuit based optoelectronic tweezers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2916954T3 true DK2916954T3 (en) | 2019-04-08 |
Family
ID=50621363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13853719.6T DK2916954T3 (en) | 2012-11-08 | 2013-10-30 | CIRCUIT BASED OPTION ELECTRONIC PINCETS |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9403172B2 (de) |
| EP (1) | EP2916954B1 (de) |
| JP (1) | JP6293160B2 (de) |
| KR (1) | KR102141261B1 (de) |
| CN (2) | CN107252733B (de) |
| CA (2) | CA3101130C (de) |
| DK (1) | DK2916954T3 (de) |
| HK (1) | HK1214558A1 (de) |
| IL (1) | IL238451B (de) |
| SG (1) | SG11201600581SA (de) |
| WO (1) | WO2014074367A1 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3783094B1 (de) | 2013-10-22 | 2023-10-11 | Berkeley Lights, Inc. | Mikrofluidische vorrichtungen zum testen einer biologischen aktivität |
| EP3760703A1 (de) | 2013-10-22 | 2021-01-06 | Berkeley Lights, Inc. | Mikrofluidische vorrichtungen mit isolationsstiften sowie verfahren zum testen biologischer mikroobjekte damit |
| US9889445B2 (en) | 2013-10-22 | 2018-02-13 | Berkeley Lights, Inc. | Micro-fluidic devices for assaying biological activity |
| US20150166326A1 (en) | 2013-12-18 | 2015-06-18 | Berkeley Lights, Inc. | Capturing Specific Nucleic Acid Materials From Individual Biological Cells In A Micro-Fluidic Device |
| US20150306599A1 (en) | 2014-04-25 | 2015-10-29 | Berkeley Lights, Inc. | Providing DEP Manipulation Devices And Controllable Electrowetting Devices In The Same Microfluidic Apparatus |
| US11192107B2 (en) | 2014-04-25 | 2021-12-07 | Berkeley Lights, Inc. | DEP force control and electrowetting control in different sections of the same microfluidic apparatus |
| US20150346148A1 (en) * | 2014-05-28 | 2015-12-03 | Agilent Technologies, Inc. | Method and Apparatus for Manipulating Samples Using Optoelectronic Forces |
| WO2015188171A1 (en) | 2014-06-06 | 2015-12-10 | Berkeley Lights, Inc. | Isolating microfluidic structures and trapping bubbles |
| KR102425337B1 (ko) * | 2014-08-15 | 2022-07-25 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 자가-잠금식 광전자 집게 및 그것의 제조 |
| EP3229961B1 (de) | 2014-12-08 | 2019-11-13 | Berkeley Lights, Inc. | Betätigte mikrofluidische strukturen für gerichtete strömung in einer mikrofluidischen vorrichtung und verfahren zur verwendung davon |
| DK3229958T3 (da) * | 2014-12-08 | 2020-11-30 | Berkeley Lights Inc | Mikrofluidanordning, der omfatter laterale/vertikale transistorstrukturer, samt fremgangsmåde til fremstilling og anvendelse heraf |
| CN107223208B (zh) | 2014-12-09 | 2021-04-09 | 伯克利之光生命科技公司 | 微流体装置中微物体的自动检测和重新定位 |
| TWI700125B (zh) * | 2014-12-10 | 2020-08-01 | 美商柏克萊燈光有限公司 | 用於操作電氣動力裝置之系統 |
| WO2016094715A2 (en) | 2014-12-10 | 2016-06-16 | Berkeley Lights, Inc. | Movement and selection of micro-objects in a microfluidic apparatus |
| CN107810059B (zh) | 2015-04-22 | 2021-03-23 | 伯克利之光生命科技公司 | 在微流体装置上冷冻和存档细胞 |
| SG11201708429WA (en) | 2015-04-22 | 2017-11-29 | Berkeley Lights Inc | Microfluidic cell culture |
| US10101250B2 (en) | 2015-04-22 | 2018-10-16 | Berkeley Lights, Inc. | Manipulation of cell nuclei in a micro-fluidic device |
| TWI712686B (zh) | 2015-04-22 | 2020-12-11 | 美商柏克萊燈光有限公司 | 用於微流體裝置之培養站 |
| EP3096134B1 (de) * | 2015-05-21 | 2019-07-24 | Nokia Technologies Oy | Vorrichtung und verfahren zur bereitstellung einer zeitvariablen spannung |
| CA3001616C (en) | 2015-10-27 | 2023-09-05 | Berkeley Lights, Inc. | Microfluidic apparatus having an optimized electrowetting surface and related systems and methods |
| US10799865B2 (en) | 2015-10-27 | 2020-10-13 | Berkeley Lights, Inc. | Microfluidic apparatus having an optimized electrowetting surface and related systems and methods |
| CN108495712A (zh) | 2015-11-23 | 2018-09-04 | 伯克利之光生命科技公司 | 原位生成的微流体隔离结构、试剂盒及其使用方法 |
| US10705082B2 (en) | 2015-12-08 | 2020-07-07 | Berkeley Lights, Inc. | In situ-generated microfluidic assay structures, related kits, and methods of use thereof |
| CA3009073C (en) | 2015-12-30 | 2024-11-12 | Berkeley Lights, Inc. | MICROFLUID DEVICES FOR OPTICALLY CONTROLLED CONVECTION AND MOVEMENT, KITS AND ASSOCIATED PROCESSES |
| WO2017117521A1 (en) | 2015-12-31 | 2017-07-06 | Berkeley Lights, Inc. | Tumor infilitrating cells engineered to express a pro-inflammatory polypeptide |
| EP3889176A1 (de) | 2016-01-15 | 2021-10-06 | Berkeley Lights, Inc. | Verfahren zur herstellung patientenspezifischer antikrebstherapeutika und verfahren zur behandlung davon |
| CN109922885B (zh) | 2016-03-16 | 2022-05-10 | 伯克利之光生命科技公司 | 用于基因组编辑克隆的选择和传代的方法、系统和装置 |
| CN109196094A (zh) | 2016-03-17 | 2019-01-11 | 伯克利之光生命科技公司 | 微流体装置中t淋巴细胞的选择和克隆 |
| JP7019590B2 (ja) | 2016-03-31 | 2022-02-15 | バークレー ライツ，インコーポレイテッド | 核酸安定化試薬、キット、及びその使用方法 |
| US10675625B2 (en) | 2016-04-15 | 2020-06-09 | Berkeley Lights, Inc | Light sequencing and patterns for dielectrophoretic transport |
| EP4684881A3 (de) | 2016-04-15 | 2026-03-18 | Bruker Cellular Analysis, Inc. | Verfahren, systeme und kits für in-pen-tests |
| CN115678773A (zh) | 2016-05-26 | 2023-02-03 | 伯克利之光生命科技公司 | 共价修饰的表面、试剂盒及制备方法和用途 |
| AU2017298545B2 (en) | 2016-07-21 | 2022-10-27 | Berkeley Lights, Inc. | Sorting of T lymphocytes in a microfluidic device |
| CA3038535A1 (en) | 2016-10-01 | 2018-04-05 | Berkeley Lights, Inc. | Dna barcode compositions and methods of in situ identification in a microfluidic device |
| CN114755412A (zh) | 2016-10-23 | 2022-07-15 | 伯克利之光生命科技公司 | 筛选b细胞淋巴细胞的方法 |
| AU2017368267B2 (en) | 2016-12-01 | 2022-12-15 | Berkeley Lights, Inc. | Apparatuses, systems and methods for imaging micro-objects |
| CA3045333A1 (en) | 2016-12-01 | 2018-06-07 | Berkeley Lights, Inc. | Automated detection and repositioning of micro-objects in microfluidic devices |
| US11473081B2 (en) | 2016-12-12 | 2022-10-18 | xCella Biosciences, Inc. | Methods and systems for screening using microcapillary arrays |
| JP7208902B2 (ja) | 2016-12-30 | 2023-01-19 | エクセラ・バイオサイエンシーズ・インコーポレイテッド | マルチステージサンプル回収システム |
| CN110546495B (zh) | 2016-12-30 | 2022-11-01 | 加利福尼亚州立大学董事会 | 用于基因组编辑t细胞的选择和传代的方法 |
| WO2018226900A2 (en) | 2017-06-06 | 2018-12-13 | Zymergen Inc. | A htp genomic engineering platform for improving fungal strains |
| TWI832820B (zh) | 2017-07-21 | 2024-02-21 | 美商伯克利之光生命科技公司 | 抗原呈現合成表面、共價功能化表面、經活化之t細胞及其用途 |
| EP3721209B1 (de) | 2017-10-15 | 2024-02-07 | Berkeley Lights, Inc. | Verfahren für in-pen-tests |
| JP7526100B2 (ja) | 2018-05-31 | 2024-07-31 | バークレー ライツ，インコーポレイテッド | マイクロ流体デバイスによる微小物体の自動検出及び特徴付け |
| WO2019236848A1 (en) | 2018-06-06 | 2019-12-12 | Zymergen Inc. | Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production |
| US11993766B2 (en) | 2018-09-21 | 2024-05-28 | Bruker Cellular Analysis, Inc. | Functionalized well plate, methods of preparation and use thereof |
| WO2020077274A1 (en) | 2018-10-11 | 2020-04-16 | Berkeley Lights, Inc. | Systems and methods for identification of optimized protein production and kits therefor |
| KR20210078526A (ko) | 2018-10-18 | 2021-06-28 | 버클리 라잇츠, 인크. | 원 항원 제시 합성 표면, 활성화된 t 세포, 및 이들의 용도 |
| CN113366312A (zh) | 2018-11-01 | 2021-09-07 | 伯克利之光生命科技公司 | 在微流体环境中测定生物细胞的方法 |
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| CN116351352A (zh) * | 2021-12-28 | 2023-06-30 | 彩科(苏州)生物科技有限公司 | 具有对称漏电流的晶体管光镊及包括该光镊的微流体设备 |
| TWI837762B (zh) * | 2022-08-10 | 2024-04-01 | 醫華生技股份有限公司 | 非接觸式分選裝置與其光感應結構、及生物微粒分選設備 |
| JP7782404B2 (ja) | 2022-09-29 | 2025-12-09 | 横河電機株式会社 | 誘電泳動装置 |
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| CA2255599C (en) | 1996-04-25 | 2006-09-05 | Bioarray Solutions, Llc | Light-controlled electrokinetic assembly of particles near surfaces |
| US6294063B1 (en) | 1999-02-12 | 2001-09-25 | Board Of Regents, The University Of Texas System | Method and apparatus for programmable fluidic processing |
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| WO2001040786A1 (en) * | 1999-12-01 | 2001-06-07 | The Regents Of The University Of California | Electric-field-assisted fluidic assembly of inorganic and organic materials, molecules and like small things including living cells |
| US6958132B2 (en) | 2002-05-31 | 2005-10-25 | The Regents Of The University Of California | Systems and methods for optical actuation of microfluidics based on opto-electrowetting |
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| WO2005100541A2 (en) | 2004-04-12 | 2005-10-27 | The Regents Of The University Of California | Optoelectronic tweezers for microparticle and cell manipulation |
| JP3952042B2 (ja) * | 2004-06-07 | 2007-08-01 | ソニー株式会社 | 凹状部位を有する電極を備えるハイブリダイゼーション検出部と該検出部を備えるｄｎａチップ |
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| CN101135680B (zh) * | 2007-07-13 | 2011-04-20 | 东南大学 | 光诱导介电泳辅助单细胞介电谱自动测试装置及测试方法 |
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| CN102764676B (zh) * | 2012-07-23 | 2014-08-06 | 西安交通大学 | 非接触式光驱动-双极电极的微流控芯片 |
| US20150166326A1 (en) * | 2013-12-18 | 2015-06-18 | Berkeley Lights, Inc. | Capturing Specific Nucleic Acid Materials From Individual Biological Cells In A Micro-Fluidic Device |
-
2013
- 2013-10-10 US US14/051,004 patent/US9403172B2/en active Active
- 2013-10-30 HK HK16102624.2A patent/HK1214558A1/zh unknown
- 2013-10-30 CA CA3101130A patent/CA3101130C/en active Active
- 2013-10-30 EP EP13853719.6A patent/EP2916954B1/de active Active
- 2013-10-30 DK DK13853719.6T patent/DK2916954T3/en active
- 2013-10-30 WO PCT/US2013/067564 patent/WO2014074367A1/en not_active Ceased
- 2013-10-30 CA CA2890352A patent/CA2890352C/en active Active
- 2013-10-30 KR KR1020157014857A patent/KR102141261B1/ko active Active
- 2013-10-30 CN CN201710258290.3A patent/CN107252733B/zh active Active
- 2013-10-30 JP JP2015540751A patent/JP6293160B2/ja active Active
- 2013-10-30 CN CN201380064064.1A patent/CN104955574B/zh active Active
- 2013-10-30 SG SG11201600581SA patent/SG11201600581SA/en unknown
-
2015
- 2015-04-26 IL IL238451A patent/IL238451B/en active IP Right Grant
-
2016
- 2016-07-11 US US15/207,210 patent/US9895699B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN107252733A (zh) | 2017-10-17 |
| CA3101130C (en) | 2023-03-14 |
| HK1214558A1 (zh) | 2016-07-29 |
| EP2916954A4 (de) | 2016-06-29 |
| EP2916954B1 (de) | 2019-01-02 |
| KR20150083890A (ko) | 2015-07-20 |
| JP2016505349A (ja) | 2016-02-25 |
| IL238451A0 (en) | 2015-06-30 |
| HK1245185A1 (zh) | 2018-08-24 |
| CN107252733B (zh) | 2020-12-01 |
| US20140124370A1 (en) | 2014-05-08 |
| EP2916954A1 (de) | 2015-09-16 |
| US9403172B2 (en) | 2016-08-02 |
| US9895699B2 (en) | 2018-02-20 |
| IL238451B (en) | 2018-04-30 |
| CA2890352C (en) | 2021-01-26 |
| SG11201600581SA (en) | 2016-03-30 |
| CA2890352A1 (en) | 2014-05-15 |
| CA3101130A1 (en) | 2014-05-15 |
| CN104955574B (zh) | 2017-05-17 |
| JP6293160B2 (ja) | 2018-03-14 |
| WO2014074367A1 (en) | 2014-05-15 |
| US20160318038A1 (en) | 2016-11-03 |
| KR102141261B1 (ko) | 2020-08-05 |
| HK1213218A1 (zh) | 2016-06-30 |
| CN104955574A (zh) | 2015-09-30 |
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