DK2921486T3 - Sammensætninger og fremgangsmåder til behandling af beta-amyloid-relaterede sygdomme - Google Patents

Sammensætninger og fremgangsmåder til behandling af beta-amyloid-relaterede sygdomme

Info

Publication number
DK2921486T3
DK2921486T3 DK14188202.7T DK14188202T DK2921486T3 DK 2921486 T3 DK2921486 T3 DK 2921486T3 DK 14188202 T DK14188202 T DK 14188202T DK 2921486 T3 DK2921486 T3 DK 2921486T3
Authority
DK
Denmark
Prior art keywords
amyloid
compositions
methods
related diseases
treating beta
Prior art date
Application number
DK14188202.7T
Other languages
English (en)
Inventor
Robert J Ternansky
Amy Allan
Greg Hook
Original Assignee
American Life Science Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Life Science Pharmaceuticals Inc filed Critical American Life Science Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2921486T3 publication Critical patent/DK2921486T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK14188202.7T 2009-08-07 2010-08-06 Sammensætninger og fremgangsmåder til behandling af beta-amyloid-relaterede sygdomme DK2921486T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23238809P 2009-08-07 2009-08-07
US23238309P 2009-08-07 2009-08-07
US29378310P 2010-01-11 2010-01-11
EP10807219.0A EP2462131B1 (en) 2009-08-07 2010-08-06 Compositions and methods for treating beta-amyloid related diseases

Publications (1)

Publication Number Publication Date
DK2921486T3 true DK2921486T3 (da) 2017-11-13

Family

ID=43544958

Family Applications (2)

Application Number Title Priority Date Filing Date
DK14188202.7T DK2921486T3 (da) 2009-08-07 2010-08-06 Sammensætninger og fremgangsmåder til behandling af beta-amyloid-relaterede sygdomme
DK10807219.0T DK2462131T3 (da) 2009-08-07 2010-08-06 Præparater og fremgangsmåder til behandling af beta-amyloid-relaterede sygdomme

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK10807219.0T DK2462131T3 (da) 2009-08-07 2010-08-06 Præparater og fremgangsmåder til behandling af beta-amyloid-relaterede sygdomme

Country Status (3)

Country Link
EP (3) EP2462131B1 (da)
DK (2) DK2921486T3 (da)
WO (1) WO2011017600A2 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015117094A1 (en) * 2014-02-03 2015-08-06 American Life Science Pharmaceuticals, Inc. Compositions and methods for synthesizing (2s,3s)-trans-epoxysuccinyl-l-leucyl-amido-3-methylbutane ethyl ester
WO2016126662A1 (en) * 2015-02-03 2016-08-11 Kardiatonos, Inc. Compounds for the prevention and treatment of vascular disease
US20190015361A1 (en) * 2017-07-17 2019-01-17 Maxwell Biosciences, Inc. Polytherapy modulating cathelicidin gene exprtession modulation for the treatment of alzheimer's disease and other conditions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1087725C (zh) * 1994-03-25 2002-07-17 同位素技术有限公司 用氘代方法增强药物效果
CN1491104A (zh) 2001-02-13 2004-04-21 新型改进释放制剂
WO2003066859A2 (en) 2002-02-07 2003-08-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Amino acid sequences capable of facilitating penetration across a biological barrier
DE10250084A1 (de) 2002-10-25 2004-05-06 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
WO2004084830A2 (en) * 2003-03-21 2004-10-07 Buck Institute Method for treating alzheimer’s dementia
US8906413B2 (en) 2003-05-12 2014-12-09 Supernus Pharmaceuticals, Inc. Drug formulations having reduced abuse potential
WO2004112747A2 (en) 2003-06-24 2004-12-29 Baxter International Inc. Specific delivery of drugs to the brain
WO2006097793A2 (en) 2004-04-15 2006-09-21 Chiasma, Ltd. Compositions capable of facilitating penetration across a biological barrier
WO2007038772A1 (en) * 2005-09-28 2007-04-05 American Life Science Pharmaceuticals Novel drugs for dementia
CN101808634A (zh) 2006-06-13 2010-08-18 利兰·斯坦福青年大学托管委员会 半胱氨酸蛋白酶的环氧化物抑制剂
WO2008037072A1 (en) 2006-09-25 2008-04-03 Merck Frosst Canada Ltd. Cathepsin b inhibitors
AU2008204335B2 (en) 2007-01-11 2013-06-13 Michael Bacher Diagnosis and treatment of Alzheimer's and other neurodementing diseases

Also Published As

Publication number Publication date
WO2011017600A2 (en) 2011-02-10
EP2462131A2 (en) 2012-06-13
DK2462131T3 (da) 2015-01-05
EP2921486B1 (en) 2017-09-27
EP2462131B1 (en) 2014-10-15
EP2921486A1 (en) 2015-09-23
WO2011017600A3 (en) 2011-06-16
EP3296295A1 (en) 2018-03-21
EP2462131A4 (en) 2013-01-02

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