DK2986611T3 - Bestemte proteinkinaseinhibitorer - Google Patents
Bestemte proteinkinaseinhibitorer Download PDFInfo
- Publication number
- DK2986611T3 DK2986611T3 DK14785167.9T DK14785167T DK2986611T3 DK 2986611 T3 DK2986611 T3 DK 2986611T3 DK 14785167 T DK14785167 T DK 14785167T DK 2986611 T3 DK2986611 T3 DK 2986611T3
- Authority
- DK
- Denmark
- Prior art keywords
- protein kinase
- kinase inhibitors
- specific protein
- specific
- inhibitors
- Prior art date
Links
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
- 239000003909 protein kinase inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361813190P | 2013-04-18 | 2013-04-18 | |
| PCT/CN2014/075664 WO2014169843A1 (en) | 2013-04-18 | 2014-04-18 | Certain protein kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2986611T3 true DK2986611T3 (da) | 2019-05-06 |
Family
ID=51730814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14785167.9T DK2986611T3 (da) | 2013-04-18 | 2014-04-18 | Bestemte proteinkinaseinhibitorer |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9556171B2 (da) |
| EP (1) | EP2986611B1 (da) |
| CN (2) | CN105121443B (da) |
| DK (1) | DK2986611T3 (da) |
| ES (1) | ES2724578T3 (da) |
| WO (1) | WO2014169843A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014169843A1 (en) | 2013-04-18 | 2014-10-23 | Shanghai Fochon Pharmaceutical Co Ltd | Certain protein kinase inhibitors |
| CN105705494B (zh) | 2013-07-18 | 2017-12-15 | 锦州奥鸿药业有限责任公司 | 喹唑啉衍生物及其药物组合物，以及作为药物的用途 |
| DK3290407T3 (da) | 2013-10-18 | 2020-03-23 | Celgene Quanticel Res Inc | Bromodomæneinhibitorer |
| WO2018009622A1 (en) | 2016-07-07 | 2018-01-11 | Bristol-Myers Squibb Company | Lactam, cyclic urea and carbamate, and triazolone derivatives as potent and selective rock inhibitors |
| TW201821408A (zh) * | 2016-12-01 | 2018-06-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 一種吡啶酮類衍生物的製備方法及其中間體 |
| CN111201225B (zh) * | 2017-06-23 | 2021-11-05 | 基石药业 | 作为mek抑制剂的类香豆素环类化合物及其应用 |
| IL303376A (en) | 2020-12-02 | 2023-08-01 | Ikena Oncology Inc | Tead inhibitors and uses thereof |
| WO2022120353A1 (en) | 2020-12-02 | 2022-06-09 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| CA3205726A1 (en) | 2021-01-25 | 2022-07-28 | Alfredo C. Castro | Combination of a 3-(imidazol-4-yl)-4-(amino)-benzenesulfonamide tead inhibitor with an egfr inhibitor and/or mek inhibitor for use in the treatment of lung cancer |
| WO2022221866A1 (en) * | 2021-04-16 | 2022-10-20 | Ikena Oncology, Inc. | Mek inhibitors and uses thereof |
| EP4346815A4 (en) * | 2021-05-27 | 2025-04-02 | Schrödinger, Inc. | HETEROCYCLIC COMPOUNDS AND METHODS OF USE |
| WO2023010354A1 (zh) * | 2021-08-04 | 2023-02-09 | 四川大学华西医院 | 一种具有egfr抑制活性的小分子化合物及其制备方法与应用 |
| WO2023114984A1 (en) | 2021-12-17 | 2023-06-22 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| KR20250040894A (ko) | 2022-05-25 | 2025-03-25 | 이케나 온콜로지, 인코포레이티드 | Mek 억제제 및 이의 용도 |
| WO2026085809A1 (zh) * | 2024-10-24 | 2026-04-30 | 上海复星医药产业发展有限公司 | 蛋白激酶抑制剂的药物组合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4223142A (en) * | 1976-06-16 | 1980-09-16 | E. R. Squibb & Sons, Inc. | Amino derivatives of pyrido(2,3-d)pyridazine carboxylic acids and esters |
| CN1045962C (zh) * | 1993-01-01 | 1999-10-27 | 森德克斯(美国)股份有限公司 | 吡啶并哒嗪酮或吡啶并哒嗪硫酮化合物,制备它的中间体,含它的药物组合物及其用途 |
| US7517994B2 (en) * | 2003-11-19 | 2009-04-14 | Array Biopharma Inc. | Heterocyclic inhibitors of MEK and methods of use thereof |
| NZ547481A (en) * | 2003-11-19 | 2009-12-24 | Array Biopharma Inc | Heterocyclic inhibitors of mek and methods of use thereof |
| CN101541801A (zh) * | 2006-08-04 | 2009-09-23 | 武田药品工业株式会社 | 稠杂环衍生物及其用途 |
| CA2714111A1 (en) * | 2008-02-25 | 2009-09-03 | Merck Sharp & Dohme Corp. | Tetrahydro-1h-pyrrolo fused pyridones |
| US20090246198A1 (en) * | 2008-03-31 | 2009-10-01 | Takeda Pharmaceutical Company Limited | Mapk/erk kinase inhibitors and methods of use thereof |
| AU2010298020B8 (en) * | 2009-09-28 | 2013-10-10 | Glaxosmithkline Llc | Combination |
| WO2014169843A1 (en) | 2013-04-18 | 2014-10-23 | Shanghai Fochon Pharmaceutical Co Ltd | Certain protein kinase inhibitors |
-
2014
- 2014-04-18 WO PCT/CN2014/075664 patent/WO2014169843A1/en not_active Ceased
- 2014-04-18 CN CN201480021868.8A patent/CN105121443B/zh active Active
- 2014-04-18 DK DK14785167.9T patent/DK2986611T3/da active
- 2014-04-18 US US14/785,205 patent/US9556171B2/en active Active
- 2014-04-18 ES ES14785167T patent/ES2724578T3/es active Active
- 2014-04-18 CN CN201710130319.XA patent/CN106905316B/zh active Active
- 2014-04-18 EP EP14785167.9A patent/EP2986611B1/en active Active
-
2016
- 2016-12-15 US US15/380,356 patent/US10022374B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2986611A4 (en) | 2016-09-14 |
| EP2986611A1 (en) | 2016-02-24 |
| CN105121443B (zh) | 2017-04-12 |
| CN106905316B (zh) | 2021-06-01 |
| EP2986611B1 (en) | 2019-02-06 |
| CN106905316A (zh) | 2017-06-30 |
| ES2724578T3 (es) | 2019-09-12 |
| CN105121443A (zh) | 2015-12-02 |
| HK1218119A1 (en) | 2017-02-03 |
| US10022374B2 (en) | 2018-07-17 |
| US20160083376A1 (en) | 2016-03-24 |
| US9556171B2 (en) | 2017-01-31 |
| US20170105994A1 (en) | 2017-04-20 |
| WO2014169843A1 (en) | 2014-10-23 |
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