DK3019604T3 - Mevalonat-diphosphat-dicarboxylase-varianter - Google Patents
Mevalonat-diphosphat-dicarboxylase-varianter Download PDFInfo
- Publication number
- DK3019604T3 DK3019604T3 DK14749728.3T DK14749728T DK3019604T3 DK 3019604 T3 DK3019604 T3 DK 3019604T3 DK 14749728 T DK14749728 T DK 14749728T DK 3019604 T3 DK3019604 T3 DK 3019604T3
- Authority
- DK
- Denmark
- Prior art keywords
- dicarboxylase
- variants
- mevalonate diphosphate
- mevalonate
- diphosphate
- Prior art date
Links
- SIGQQUBJQXSAMW-ZCFIWIBFSA-N (R)-5-diphosphomevalonic acid Chemical compound OC(=O)C[C@@](O)(C)CCOP(O)(=O)OP(O)(O)=O SIGQQUBJQXSAMW-ZCFIWIBFSA-N 0.000 title 1
- XAZKFISIRYLAEE-UHFFFAOYSA-N CC1CC(C)CC1 Chemical compound CC1CC(C)CC1 XAZKFISIRYLAEE-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01033—Diphosphomevalonate decarboxylase (4.1.1.33), i.e. mevalonate-pyrophosphate decarboxylase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13175790 | 2013-07-09 | ||
| PCT/EP2014/064767 WO2015004211A2 (en) | 2013-07-09 | 2014-07-09 | Mevalonate diphosphate decarboxylase variants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3019604T3 true DK3019604T3 (da) | 2020-10-26 |
Family
ID=48747458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14749728.3T DK3019604T3 (da) | 2013-07-09 | 2014-07-09 | Mevalonat-diphosphat-dicarboxylase-varianter |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11261438B2 (da) |
| EP (1) | EP3019604B1 (da) |
| CN (1) | CN105408477B (da) |
| CA (1) | CA2913225A1 (da) |
| DK (1) | DK3019604T3 (da) |
| ES (1) | ES2824029T3 (da) |
| PL (1) | PL3019604T3 (da) |
| WO (1) | WO2015004211A2 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10407669B2 (en) * | 2015-07-28 | 2019-09-10 | Global Bioenergies | HIV kinase variants |
| CN107922937B (zh) * | 2015-08-03 | 2022-03-15 | 国立研究开发法人理化学研究所 | 二磷酸甲羟戊酸脱羧酶变异体、和利用了该变异体的烯烃化合物的制造方法 |
| CN109715815B (zh) * | 2016-09-28 | 2022-11-29 | 国立研究开发法人理化学研究所 | 二磷酸甲羟戊酸脱羧酶变异体、和利用了该变异体的烯烃化合物的制造方法 |
| EP3578649A4 (en) | 2017-02-01 | 2020-11-25 | Riken | DIPHOSPHOMEVALONATE DECARBOXYLASE VARIANT AND PROCESS FOR MANUFACTURING AN OLEFIN COMPOUND BY MEANS OF THE SAME |
| EP3502216A1 (en) | 2017-12-21 | 2019-06-26 | Global Bioenergies | Gasoline composition enabling reduced particulate emissions |
| BR112021000598A2 (pt) | 2018-07-27 | 2021-04-13 | Global Bioenergies | Método para produzir frutose-6-fosfato, micro-organismo recombinante, combinação de enzimas, composição e uso do micro-organismo |
| CN109251940B (zh) * | 2018-10-30 | 2020-10-16 | 浙江华睿生物技术有限公司 | 一种产β-羟基-β-甲基丁酸工程菌的构建方法 |
| JP7504112B2 (ja) | 2019-02-20 | 2024-06-21 | ブラスケム エス．エー． | ヘキソースからの含酸素化合物の生成のための微生物および方法 |
| CN113710798B (zh) | 2019-02-20 | 2025-09-23 | 布拉斯科公司 | 戊糖和己糖的降解途径 |
| WO2021063958A1 (en) | 2019-09-30 | 2021-04-08 | Global Bioenergies | Improved means and methods for increasing the yield of acetyl-coa from glucose |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| PT2304040T (pt) * | 2008-07-04 | 2017-11-21 | Scientist Of Fortune Sa | Produção de alcenos por descarboxilação enzimática de ácidos 3-hidroxi-alcanoicos |
| AU2009357243B2 (en) * | 2009-12-22 | 2014-07-03 | Global Bioenergies | Process for the production of isoprenol from mevalonate employing a diphosphomevalonate decarboxylase |
| DE102009060506A1 (de) * | 2009-12-23 | 2011-06-30 | Giesecke & Devrient GmbH, 81677 | Sicherheitselement und Herstellverfahren dafür |
| PH12013500553A1 (en) * | 2010-10-19 | 2013-05-06 | Global Bioenergies | Production of alkenes by combined enzymatic conversion of 3-hydroxyalkanoic acids |
-
2014
- 2014-07-09 DK DK14749728.3T patent/DK3019604T3/da active
- 2014-07-09 US US14/903,945 patent/US11261438B2/en active Active
- 2014-07-09 CN CN201480039197.8A patent/CN105408477B/zh active Active
- 2014-07-09 ES ES14749728T patent/ES2824029T3/es active Active
- 2014-07-09 PL PL14749728T patent/PL3019604T3/pl unknown
- 2014-07-09 WO PCT/EP2014/064767 patent/WO2015004211A2/en not_active Ceased
- 2014-07-09 EP EP14749728.3A patent/EP3019604B1/en active Active
- 2014-07-09 CA CA2913225A patent/CA2913225A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015004211A2 (en) | 2015-01-15 |
| WO2015004211A3 (en) | 2015-03-12 |
| US20160160204A1 (en) | 2016-06-09 |
| ES2824029T3 (es) | 2021-05-11 |
| US11261438B2 (en) | 2022-03-01 |
| PL3019604T3 (pl) | 2021-01-25 |
| CN105408477B (zh) | 2025-05-27 |
| CN105408477A (zh) | 2016-03-16 |
| EP3019604B1 (en) | 2020-08-26 |
| EP3019604A2 (en) | 2016-05-18 |
| CA2913225A1 (en) | 2015-01-15 |
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