DK301986A - Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser - Google Patents

Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser Download PDF

Info

Publication number
DK301986A
DK301986A DK301986A DK301986A DK301986A DK 301986 A DK301986 A DK 301986A DK 301986 A DK301986 A DK 301986A DK 301986 A DK301986 A DK 301986A DK 301986 A DK301986 A DK 301986A
Authority
DK
Denmark
Prior art keywords
hydroxyvitamin
preparing
compounds
Prior art date
Application number
DK301986A
Other languages
English (en)
Other versions
DK153943B (da
DK301986D0 (da
DK153943C (da
Inventor
Hector F Deluca
Heinrich K Schnoes
Seok Ho Lee
Mary E Phelps
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK301986D0 publication Critical patent/DK301986D0/da
Publication of DK301986A publication Critical patent/DK301986A/da
Publication of DK153943B publication Critical patent/DK153943B/da
Application granted granted Critical
Publication of DK153943C publication Critical patent/DK153943C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK301986A 1984-11-01 1986-06-26 Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser ud fra 1-hydroxy-3,5-cyclovitamin-d-forbindelser DK153943C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/667,296 US4555364A (en) 1984-11-01 1984-11-01 Method for preparing 1-hydroxyvitamin D compounds
US66729684 1984-11-01
US8501995 1985-10-15
PCT/US1985/001995 WO1986002649A1 (en) 1984-11-01 1985-10-15 Method for preparing 1-hydroxyvitamin d compounds

Publications (4)

Publication Number Publication Date
DK301986D0 DK301986D0 (da) 1986-06-26
DK301986A true DK301986A (da) 1986-06-26
DK153943B DK153943B (da) 1988-09-26
DK153943C DK153943C (da) 1989-01-30

Family

ID=24677643

Family Applications (1)

Application Number Title Priority Date Filing Date
DK301986A DK153943C (da) 1984-11-01 1986-06-26 Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser ud fra 1-hydroxy-3,5-cyclovitamin-d-forbindelser

Country Status (12)

Country Link
US (1) US4555364A (da)
EP (1) EP0198892B1 (da)
JP (1) JPS62500717A (da)
KR (1) KR920004488B1 (da)
AU (1) AU589580B2 (da)
CA (1) CA1233187A (da)
DE (1) DE3581200D1 (da)
DK (1) DK153943C (da)
IE (1) IE58164B1 (da)
IL (1) IL76754A (da)
NZ (1) NZ213844A (da)
WO (1) WO1986002649A1 (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869473A (en) * 1988-08-02 1999-02-09 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US5602116A (en) * 1988-08-02 1997-02-11 Bone Care International, Inc. Method for treating and preventing secondary hyperparathyroidism
NZ232734A (en) * 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
US5763428A (en) * 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
US5801164A (en) * 1990-09-21 1998-09-01 Bone Care International, Inc. Methods of treating osteoporosis prophylactically or therapeutically
US6025346A (en) * 1990-09-21 2000-02-15 Bone Care International, Inc. 1α-hydroxy vitamin D4 and novel intermediates and analogues
US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5763429A (en) * 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US6121469A (en) * 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
US5869472A (en) * 1994-07-18 1999-02-09 Bone Care International, Inc. Synthesis of 1α-hydroxy vitamin D
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6242434B1 (en) 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US6376479B1 (en) 1995-04-03 2002-04-23 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
CA2279590A1 (en) * 1997-02-13 1998-08-20 Bone Care International, Inc. Targeted therapeutic delivery of vitamin d compounds
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
WO2002006218A2 (en) * 2000-07-18 2002-01-24 Bone Care International, Inc. STABILIZED 1α-HYDROXY VITAMIN D
US7148211B2 (en) 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20050239756A1 (en) * 2004-04-23 2005-10-27 Bone Care International, Inc. Methods of treating various vitamin D metabolism conditions with 1alpha-hydroxyvitamin D2
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
CA2924200C (en) * 2005-10-12 2017-09-05 Proventiv Therapeutics, Llc Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency
SI1993559T1 (sl) 2006-02-03 2017-01-31 Opko Renal, Llc Zdravljenje nezadostnosti in pomanjkanja vitamina D s 25-hidroksivitaminon D2 in 25-hidroksivitaminom D3
PT3357496T (pt) 2006-06-21 2020-05-12 Opko Ireland Global Holdings Ltd Terapia utilizando um agente de repleção de vitamina d e um agente de substituição hormonal de vitamina d
PL3225243T3 (pl) 2007-04-25 2025-12-22 Opko Renal, Llc Sposób bezpiecznego i skutecznego leczenia i zapobiegania wtórnej nadczynności przytarczyc w przewlekłej chorobie nerek
CN101668532B (zh) * 2007-04-25 2014-08-20 赛特克罗公司 治疗维生素d不足和缺乏、继发性甲状旁腺功能亢进症和维生素d-响应疾病的组合物及其相应的制药用途
KR20190141269A (ko) 2007-04-25 2019-12-23 사이토크로마 인코포레이티드 비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
US8592401B2 (en) * 2007-04-25 2013-11-26 Proventiv Therapeutics, Llc Methods and compounds for vitamin D therapy
CN102046812A (zh) 2008-04-02 2011-05-04 赛特克罗公司 用于维生素d缺乏症和相关障碍的方法、组合物、用途和试剂盒
CA2797537C (en) 2010-03-29 2021-11-23 Cytochroma Inc. Use of 25-hydroxyvitamin d compound for reducing parathyroid levels
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
EP4596045A3 (en) 2016-03-28 2025-10-15 EirGen Pharma Ltd. Methods of vitamin d treatment
CN117126090A (zh) * 2023-09-01 2023-11-28 正大制药（青岛）有限公司 一种骨化醇类原料药5,6-trans杂质的除杂方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195027A (en) * 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4234495A (en) * 1979-09-10 1980-11-18 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxyvitamin D compounds from 1α-hydroxy-3,5-cyclovitamin D compounds
US4367177A (en) * 1981-04-15 1983-01-04 Wisconsin Alumni Research Foundation Process for preparing 23,25-dihydroxyvitamin D3
US4512925A (en) * 1983-09-14 1985-04-23 Wisconsin Alumini Research Foundation 1,23-Dihydroxyvitamin D compounds
US4554106A (en) * 1984-11-01 1985-11-19 Wisconsin Alumni Research Foundation Method for preparing 1α-hydroxyvitamin D compounds

Also Published As

Publication number Publication date
EP0198892B1 (en) 1990-12-27
AU4867485A (en) 1986-05-15
JPH0432062B2 (da) 1992-05-28
JPS62500717A (ja) 1987-03-26
DK153943B (da) 1988-09-26
DE3581200D1 (de) 1991-02-07
IE852706L (en) 1986-05-01
KR920004488B1 (ko) 1992-06-05
US4555364A (en) 1985-11-26
DK301986D0 (da) 1986-06-26
NZ213844A (en) 1989-08-29
IE58164B1 (en) 1993-07-28
IL76754A (en) 1989-10-31
WO1986002649A1 (en) 1986-05-09
IL76754A0 (en) 1986-02-28
DK153943C (da) 1989-01-30
EP0198892A1 (en) 1986-10-29
EP0198892A4 (en) 1987-03-12
CA1233187A (en) 1988-02-23
AU589580B2 (en) 1989-10-19
KR860700353A (ko) 1986-10-06

Similar Documents

Publication Publication Date Title
DK301986D0 (da) Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser
DK162647C (da) Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner
DK280182A (da) Fremgangsmaade til fremstilling af n-aryl-piperazinalkanamider
DK470583D0 (da) Fremgangsmade til fremstilling af 1-phenyl-2-piperidinopropanolderivater
DK302086A (da) Fremgangsmaade til fremstilling af 1 alfa-hydroxyvitamin-d-forbindelser
DK492783D0 (da) Fremgangsmade til fremstilling af 3-aryl-5-pyrazol-derivater
DK95483D0 (da) Fremgangsmade til fremstilling af tetrahydropyranderivater
DK379985D0 (da) Fremgangsmaade til fremstilling af 6-chlor-n-methyl-2,3,4,5-tetrahydro-lh-benzazepin
DK183583D0 (da) Fremgangsmade til fremstilling af benzoazacycloalkyl-spiro-imidazolidiner
DK160829C (da) Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner
DK156085D0 (da) Fremgangsmaade til fremstilling af acetoxyazetidinoner
DK370582A (da) Fremgangsmaade til fremstilling af 2-beta-d-ribofuranosylthiazol-4-carboxamid
DK159309C (da) Fremgangsmaade til fremstilling af 4-metyl-5-alkylthiometyl-imidazoler
DK161706C (da) Fremgangsmaade til fremstilling af pyrido-imidazo-rifamyciner
DK40883D0 (da) Fremgangsmade til fremstilling af benzothienylallylaminer
DK369181A (da) Fremgangsmaade til fremstilling af triazolylvinylketonforbindelser
DK518883A (da) Fremgangsmaade til fremstilling af 1-oxa-beta-lactam-forbindelser
DK399783A (da) Fremgangsmaade til fremstilling af substituerede 1-pyridyloxy-3-indolylalkylamino-2-propanoler
DK190385D0 (da) Fremgangsmaade til fremstilling af cephalosporinforbindelser
DK457983D0 (da) Fremgangsmade til fremstilling af beta-lactam
DK156061C (da) Fremgangsmaade til fremstilling af 2-alkyl-4-amino-5-aminomethylpyrimidin
DK432683D0 (da) Fremgangsmade til fremstilling af 2-hydroxy-2-phenylethylaminer
DK163925C (da) Fremgangsmaade til fremstilling af cephalosporinforbindelser
KR860004941A (ko) 아실-락탐화합물을 제조하는 방법
DK229986D0 (da) Fremgangsmaade til fremstilling af 2-thiocromenylidenethylacetoacetater

Legal Events

Date Code Title Description
PUP Patent expired