DK3025743T3 - Lægemiddelafgivelsesindretning - Google Patents

Lægemiddelafgivelsesindretning Download PDF

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Publication number
DK3025743T3
DK3025743T3 DK15194751.2T DK15194751T DK3025743T3 DK 3025743 T3 DK3025743 T3 DK 3025743T3 DK 15194751 T DK15194751 T DK 15194751T DK 3025743 T3 DK3025743 T3 DK 3025743T3
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DK
Denmark
Prior art keywords
distal
proximal
piston rod
actuator
locking means
Prior art date
Application number
DK15194751.2T
Other languages
English (en)
Inventor
Sebastian Karlsson
Gunnar Elmén
Original Assignee
Shl Group Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shl Group Ab filed Critical Shl Group Ab
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Publication of DK3025743T3 publication Critical patent/DK3025743T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/2451—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing preventing delivery before mixing is completed, e.g. by locking mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Enzymes And Modification Thereof (AREA)

Claims (10)

1. Injektionsindretning til manuel penetrering med en på indretningen anbragt kanyle ind i et injektionssted og automatisk injektion af et lægemiddel, hvilken indretning omfatter en distal husdel (10); en proksimal husdel (12), hvori en lægemiddelbeholder (20) er anbragt; en stempelstang (40) indrettet til at virke på en distal stopper (21), som er anbragt inden i beholderen (20); en trykknap (70), der rager ud fra den distale husdel (10) og er interaktivt forbundet til stempelstangen; et aktiveringsorgan (30) omfattende et rørformet, bøjeligt låseorgan (34), der er løsbart forbundet til stempelstangen (40), hvor det rørformede, bøjelige låseorgan (34) omfatter hovedsageligt radialt indadrettede lister (33), og at stempelstangen (40) omfatter en periferirille (46), der har en form, som får listerne (33) til at passe i rillen; et drivkraftorgan (100), der er anbragt forspændt mellem en proksimal endeflade (31) af aktiveringsorganet (30) og en endevæg (41) af stempelstangen; et låseorgan (50) anbragt koaksialt omkring aktiveringsorganet (30) og distalt forskydeligt i forhold til aktiveringsorganet (30) mellem en første position, hvor låseorganet (50) helt omslutter det rørformede, bøjelige låseorgan (34), mens det holder stempelstangen (40) og dermed drivkraftorganet (100) i en forspændt tilstand, og en anden position, hvor låseorganet (50) delvis omslutter det rørformede, bøjelige låseorgan (34); en styrestang (60) anbragt koaksialt inden i drivkraftorganet (100) og funktionelt forbundet til aktiveringsorganet (30), hvor en proksimal del af styrestangen (60) rager gennem endevæggen (41) af stempelstangen (40) til bestemmelse af en første forudbestemt afstand (A) mellem endevæggen (41) og den distale stopper (21), og hvor den, når trykknappen (70) forskydes proksimalt, tvinger stempelstangen (40), aktiveringsorganet (30) og styrestangen (60) til proksimal forskydning, hvorved det rørformede, bøjelige låseorgan (34) kommer helt fri af kontakt med låseorganet (50) og med stempelstangen (40), hvilket primært tillader stempelstangen (40) at forskydes proksimalt den første forudbestemte afstand (A) via kraften af det forspændte drivkraftorgan (100).
2. Indretning ifølge krav 1, hvor indretningen yderligere omfatter en trykfjeder (80) anbragt mellem mindst to modsat anbragte stoplister (39) af aktiveringsorganet (30) og en ringformet liste (52) i låseorganet (50).
3. Indretning ifølge krav 2, hvor trykknappen (70) omfatter mindst to første proksimalt udstrakte tunger (71), og hvor hver tunge har en proksimal overflade til at støde mod en distal, ringformet overflade af stempelstangen.
4. Indretning ifølge ethvert af de foregående krav, hvor det bøjelige låseorgan (34) danner bøjelige tunger, hvor hver tunge har en skrå overgangsoverflade (90), der mødes med en båndformet del (38) med forøget diameter til dannelse af den proksimale ringformede overflade af det rørformede, bøjelige låseorgan (34).
5. Indretning ifølge krav 4, hvor aktiveringsorganet (30) yderligere er udstyret med bøjelige krogorganer (32) til dannelse af mindst én bøjelig tunge, der har en radialt udad rettet krog (37) ved dens ydre ende og har et fremspring (35) med en skrå overflade.
6. Indretning ifølge krav 5, hvor de bøjelige krogorganer (32) er indrettet til at interagere med ringformede holdeorganer (11), der er dannet som en U-formet liste anbragt på den indre periferioverflade af den distale husdel (10).
7. Indretning ifølge ethvert af de foregående krav, hvor aktiveringsorganet (30) også er udformet med mindst ét radialt udad rettet fremspring (36), der interagerer med mindst én på langs udstrakt spalte (73) i trykknappen (70), således at aktiveringsorganet (30) kan bevæges på langs i forhold til trykknappen (70).
8. Indretning ifølge ethvert af de foregående krav, hvor aktiveringsorganet (30) også omfatter mindst to modsat anbragte stoplister (39) rettet radialt udad fra den ydre overflade på hver side.
9. Indretning ifølge krav 8, hvor låseorganet (50) ved dets distale ende omfatter mindst to modsat anbragte udskæringer af en hovedsagelig rektangulær form under dannelse af mindst to distalt udstrakte tunger (51), og hvor bredderne af udskæringerne svarer til bredden af aktiveringsorganets (30) stoplister (39).
10. Indretning ifølge ethvert af kravene 4 til 9, hvor de elastiske egenskaber af det rørformede, bøjelige låseorgan (34) i aktiveringsorganet (30) er således, at det tvinger den båndformede del (38) til at bøje radialt udad og bringe listerne (33) til at komme ud af rillen (46) i stempelstangen (40).
DK15194751.2T 2010-02-09 2011-01-12 Lægemiddelafgivelsesindretning DK3025743T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30260710P 2010-02-09 2010-02-09
SE1050128 2010-02-09
EP11742550.4A EP2533834B1 (en) 2010-02-09 2011-01-12 Medicament delivery device

Publications (1)

Publication Number Publication Date
DK3025743T3 true DK3025743T3 (da) 2018-10-15

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DK15194751.2T DK3025743T3 (da) 2010-02-09 2011-01-12 Lægemiddelafgivelsesindretning
DK11742550.4T DK2533834T3 (da) 2010-02-09 2011-01-12 Medikamentafgivelsesindretning

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Country Status (7)

Country Link
US (1) US8986245B2 (da)
EP (2) EP2533834B1 (da)
CN (1) CN102821801B (da)
AU (1) AU2011214922B2 (da)
DK (2) DK3025743T3 (da)
TW (1) TWI421108B (da)
WO (1) WO2011099918A1 (da)

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Also Published As

Publication number Publication date
EP2533834B1 (en) 2017-11-15
WO2011099918A1 (en) 2011-08-18
EP3025743A3 (en) 2016-08-31
TW201127433A (en) 2011-08-16
CN102821801A (zh) 2012-12-12
AU2011214922A1 (en) 2012-08-09
EP3025743B1 (en) 2018-08-08
TWI421108B (zh) 2014-01-01
CN102821801B (zh) 2014-10-01
EP2533834A4 (en) 2016-08-31
EP3025743A2 (en) 2016-06-01
US20120310156A1 (en) 2012-12-06
EP2533834A1 (en) 2012-12-19
US8986245B2 (en) 2015-03-24
DK2533834T3 (da) 2018-01-15
AU2011214922B2 (en) 2012-12-13

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