DK3042205T3 - Fremgangsmåde til forbedring af antistofstabilitet - Google Patents
Fremgangsmåde til forbedring af antistofstabilitet Download PDFInfo
- Publication number
- DK3042205T3 DK3042205T3 DK14758893.3T DK14758893T DK3042205T3 DK 3042205 T3 DK3042205 T3 DK 3042205T3 DK 14758893 T DK14758893 T DK 14758893T DK 3042205 T3 DK3042205 T3 DK 3042205T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibody stability
- improving antibody
- improving
- stability
- antibody
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—RNA viruses
- C07K16/102—Coronaviridae (F)
- C07K16/104—Severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
- G16B15/20—Protein or domain folding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C99/00—Subject matter not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Evolutionary Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Computing Systems (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13183389 | 2013-09-06 | ||
| EP13184174 | 2013-09-12 | ||
| PCT/EP2014/068649 WO2015032776A1 (en) | 2013-09-06 | 2014-09-03 | Method for improving antibody stability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3042205T3 true DK3042205T3 (da) | 2020-03-02 |
Family
ID=51485608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14758893.3T DK3042205T3 (da) | 2013-09-06 | 2014-09-03 | Fremgangsmåde til forbedring af antistofstabilitet |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10418126B2 (da) |
| EP (2) | EP3761033A3 (da) |
| JP (1) | JP6580570B2 (da) |
| KR (1) | KR20160052562A (da) |
| CN (1) | CN105518461B (da) |
| CA (1) | CA2918191A1 (da) |
| DK (1) | DK3042205T3 (da) |
| MX (1) | MX2016002720A (da) |
| RU (1) | RU2711719C2 (da) |
| WO (1) | WO2015032776A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014306867B2 (en) | 2013-08-12 | 2017-10-26 | Genentech, Inc. | Compositions and method for treating complement-associated conditions |
| EP3137503A1 (en) | 2014-05-01 | 2017-03-08 | Genentech, Inc. | Anti-factor d antibody variants and uses thereof |
| US10407510B2 (en) | 2015-10-30 | 2019-09-10 | Genentech, Inc. | Anti-factor D antibodies and conjugates |
| WO2017075252A1 (en) * | 2015-10-30 | 2017-05-04 | Genentech, Inc. | Anti-factor d antibody variant conjugates and uses thereof |
| WO2021025940A1 (en) * | 2019-08-02 | 2021-02-11 | Genentech, Inc. | Prediction of side-chain degradation in polymers through physics based simulations |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US100736A (en) * | 1870-03-15 | dundeedale | ||
| RU2134724C1 (ru) * | 1992-08-24 | 1999-08-20 | Ниссин Сокухин Кабусики Кайся | Гуманизированное антитело и способ его получения, полинуклеотид (варианты), гибридомная клеточная линия (варианты) |
| US8278262B2 (en) * | 2004-09-21 | 2012-10-02 | Biontech Ag | Use of microproteins as tryptase inhibitors |
| KR101516823B1 (ko) * | 2006-03-17 | 2015-05-07 | 바이오겐 아이덱 엠에이 인코포레이티드 | 안정화된 폴리펩티드 조성물 |
| IN2009DN05758A (da) * | 2007-03-12 | 2015-07-24 | Esbatech Ag | |
| PL3241843T3 (pl) * | 2008-06-25 | 2021-12-27 | Novartis Ag | Optymalizacja rozpuszczalności cząsteczek immunowiążących |
| US9598682B2 (en) * | 2009-09-29 | 2017-03-21 | Vib Vzw | Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose |
| EP3119490B1 (en) * | 2014-03-21 | 2021-09-08 | F. Hoffmann-La Roche AG | In vitro prediction of in vivo half-life of antibodies |
| EP3122762A1 (en) * | 2014-03-28 | 2017-02-01 | Novozymes A/S | Enzyme variants and polynucleotides encoding same |
| CA2950273C (en) * | 2014-05-30 | 2022-06-21 | Novozymes A/S | Variants of gh family 11 xylanase and polynucleotides encoding same |
-
2014
- 2014-09-03 EP EP19217274.0A patent/EP3761033A3/en not_active Withdrawn
- 2014-09-03 JP JP2016539511A patent/JP6580570B2/ja not_active Expired - Fee Related
- 2014-09-03 CA CA2918191A patent/CA2918191A1/en not_active Abandoned
- 2014-09-03 RU RU2016111352A patent/RU2711719C2/ru not_active IP Right Cessation
- 2014-09-03 MX MX2016002720A patent/MX2016002720A/es unknown
- 2014-09-03 WO PCT/EP2014/068649 patent/WO2015032776A1/en not_active Ceased
- 2014-09-03 EP EP14758893.3A patent/EP3042205B1/en active Active
- 2014-09-03 KR KR1020167005951A patent/KR20160052562A/ko not_active Ceased
- 2014-09-03 DK DK14758893.3T patent/DK3042205T3/da active
- 2014-09-03 CN CN201480048544.3A patent/CN105518461B/zh not_active Expired - Fee Related
-
2016
- 2016-03-04 US US15/061,130 patent/US10418126B2/en not_active Expired - Fee Related
-
2019
- 2019-08-02 US US16/530,375 patent/US20200066372A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HK1223684A1 (zh) | 2017-08-04 |
| RU2016111352A3 (da) | 2018-05-23 |
| RU2016111352A (ru) | 2017-10-11 |
| EP3761033A2 (en) | 2021-01-06 |
| CA2918191A1 (en) | 2015-03-12 |
| MX2016002720A (es) | 2016-06-08 |
| WO2015032776A1 (en) | 2015-03-12 |
| US10418126B2 (en) | 2019-09-17 |
| US20200066372A1 (en) | 2020-02-27 |
| EP3042205A1 (en) | 2016-07-13 |
| CN105518461B (zh) | 2018-04-13 |
| US20160275238A1 (en) | 2016-09-22 |
| CN105518461A (zh) | 2016-04-20 |
| EP3042205B1 (en) | 2019-12-25 |
| JP6580570B2 (ja) | 2019-09-25 |
| RU2711719C2 (ru) | 2020-01-21 |
| EP3761033A3 (en) | 2021-01-20 |
| JP2016530288A (ja) | 2016-09-29 |
| KR20160052562A (ko) | 2016-05-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL243311A0 (en) | Novel antibody frameworks | |
| DK3083540T3 (da) | Fremgangsmåde til fremstilling af substituerede phenoxyphenylketoner | |
| DK3336106T3 (da) | Anti-fcrh5-antistoffer | |
| EP3083682C0 (en) | DOUBLE SPECIFICITY ANTIBODIES | |
| DK3708583T3 (da) | Ikke-fucosylerede anti-fgfr2iiib-antistoffer | |
| LT3049441T (lt) | Anti-pdl1 antikūnų kompozicija | |
| FI20135292L (fi) | Menetelmä kartongin valmistamiseksi | |
| DK3071595T3 (da) | Humaniseret anti-kallikrein-2-antistof | |
| DK2972353T3 (da) | Forbedrede fremgangsmåder til udførelse af multipleksanalyser | |
| DK3016991T3 (da) | Sammensætninger til formning af væsker | |
| DK3300610T3 (da) | Fremgangsmåde til fraktionering af opløselige ærter | |
| DK2969098T3 (da) | Fremgangsmåder til oprensning af antistoffer | |
| DK3068800T3 (da) | FcRn-specifikke antistoffer | |
| DK3332813T3 (da) | Metode til opregulering af antigenekspression | |
| DK3033708T3 (da) | Fremgangsmåde til evaluering af et dokument | |
| BR112015021083A2 (pt) | método | |
| DK2983680T3 (da) | Forbedring af organer til transplantation | |
| HRP20190085T1 (hr) | Anti-cd52 protutijela | |
| DK3065774T3 (da) | Anti-CCL17-antistoffer | |
| DK3083493T3 (da) | Fremgangsmåde til fremstilling af syntesegas | |
| BR112015029076A2 (pt) | método | |
| DK3024576T3 (da) | Fremgangsmåde til opstart af en fischer-tropsch-proces | |
| DK3016682T3 (da) | Metoder til behandling af kræft | |
| DK2786852T3 (da) | Metode til laminering af rørfolie | |
| FI20135361L (fi) | Analyyttinen menetelmä |