DK3056208T3 - Immunpotentiator - Google Patents

Immunpotentiator Download PDF

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Publication number
DK3056208T3
DK3056208T3 DK14852637.9T DK14852637T DK3056208T3 DK 3056208 T3 DK3056208 T3 DK 3056208T3 DK 14852637 T DK14852637 T DK 14852637T DK 3056208 T3 DK3056208 T3 DK 3056208T3
Authority
DK
Denmark
Prior art keywords
immunpotentiator
Prior art date
Application number
DK14852637.9T
Other languages
English (en)
Inventor
Yoichiro Koshi
Joonsik Park
Jiao Lu
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Application granted granted Critical
Publication of DK3056208T3 publication Critical patent/DK3056208T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/718Starch or degraded starch, e.g. amylose, amylopectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593Polyesters, e.g. PLGA or polylactide-co-glycolide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55583Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK14852637.9T 2013-10-09 2014-10-09 Immunpotentiator DK3056208T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013212103 2013-10-09
PCT/JP2014/077038 WO2015053354A1 (ja) 2013-10-09 2014-10-09 免疫賦活化剤

Publications (1)

Publication Number Publication Date
DK3056208T3 true DK3056208T3 (en) 2021-11-15

Family

ID=52813169

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14852637.9T DK3056208T3 (en) 2013-10-09 2014-10-09 Immunpotentiator

Country Status (14)

Country Link
US (1) US10556004B2 (da)
EP (1) EP3056208B1 (da)
JP (1) JP6146676B2 (da)
KR (1) KR102343005B1 (da)
CN (1) CN105611936B (da)
AU (1) AU2014332835B2 (da)
BR (1) BR112016007130B1 (da)
CA (1) CA2926720A1 (da)
DK (1) DK3056208T3 (da)
ES (1) ES2887367T3 (da)
MX (1) MX386144B (da)
PL (1) PL3056208T3 (da)
RU (1) RU2702987C2 (da)
WO (1) WO2015053354A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110237249A (zh) * 2018-03-09 2019-09-17 南开大学 特异靶向树突状细胞的新型铝佐剂及在疫苗制备上的应用
TWI862656B (zh) * 2019-08-09 2024-11-21 日商三菱商事生命科學股份有限公司 生活習慣病預防或改善用組成物
CA3230661A1 (en) * 2021-08-30 2023-03-09 Toray Industries, Inc. Composition for enhancing immunogenicity
KR20240054289A (ko) 2021-08-30 2024-04-25 도레이 카부시키가이샤 면역원성 증강용 조성물
KR20240065074A (ko) 2021-09-16 2024-05-14 도레이 카부시키가이샤 암의 치료 및/또는 예방을 위한 의약품
CN119684489A (zh) * 2024-12-16 2025-03-25 南京农业大学 一种聚乙烯亚胺修饰的昆布多糖及其制备方法和应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3871892A (en) * 1972-12-18 1975-03-18 Hayashibara Biochem Lab Shaped bodies of pullulan esters and their use
US5032401A (en) * 1989-06-15 1991-07-16 Alpha Beta Technology Glucan drug delivery system and adjuvant
EP0640348A1 (en) 1993-07-26 1995-03-01 Akzo Nobel N.V. Oil-based and water-based adjuvant mixture
JP4091136B2 (ja) 1997-01-17 2008-05-28 キリンフードテック株式会社 免疫賦活剤
US20040057958A1 (en) * 2002-05-17 2004-03-25 Waggoner David W. Immunogenicity-enhancing carriers and compositions thereof and methods of using the same
KR100649855B1 (ko) 2003-03-07 2006-11-28 가부시키가이샤 아우레오 β-글루칸 함유 조성물 및 상기 조성물을 이용한 변비개선제, 면역 부활제 및 피부용 보습제
JP5138954B2 (ja) 2006-03-09 2013-02-06 独立行政法人科学技術振興機構 両親媒性高分子複合体
JP6082174B2 (ja) * 2006-11-06 2017-02-15 ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ 免疫調節組成物及びその使用方法
US9439954B2 (en) 2007-11-26 2016-09-13 Glaxosmithkline Biologicals Sa Conjugated beta-1,3-linked glucans
WO2009077854A2 (en) 2007-11-26 2009-06-25 Novartis Ag Adjuvanted glucans
EP2244695A1 (en) 2007-12-07 2010-11-03 Novartis AG Compositions for inducing immune responses
CN101932311B (zh) * 2008-02-22 2014-07-16 东丽株式会社 微粒及其药物组合物
JP5429707B2 (ja) 2008-03-27 2014-02-26 国立大学法人群馬大学 微粒子およびその製造方法
BRPI1005919B1 (pt) 2009-02-27 2021-06-22 Toray Industries, Inc Composição imunogênica
ES2829819T3 (es) 2010-08-26 2021-06-02 Toray Industries Composición inmunogénica
GB201020193D0 (en) * 2010-11-29 2011-01-12 Biotec Pharmacon Asa Glucan compositions
JP2013067709A (ja) 2011-09-21 2013-04-18 Gunze Ltd ヒアルロン酸修飾物

Also Published As

Publication number Publication date
AU2014332835A1 (en) 2016-04-28
WO2015053354A1 (ja) 2015-04-16
RU2016116786A (ru) 2017-11-15
BR112016007130B1 (pt) 2023-01-31
JPWO2015053354A1 (ja) 2017-03-09
AU2014332835B2 (en) 2019-07-25
EP3056208B1 (en) 2021-08-18
MX2016004328A (es) 2016-07-11
ES2887367T3 (es) 2021-12-22
KR102343005B1 (ko) 2021-12-24
JP6146676B2 (ja) 2017-06-14
EP3056208A4 (en) 2017-06-14
RU2016116786A3 (da) 2018-08-01
CA2926720A1 (en) 2015-04-16
US20160256543A1 (en) 2016-09-08
MX386144B (es) 2025-03-18
RU2702987C2 (ru) 2019-10-15
BR112016007130A2 (pt) 2020-06-16
US10556004B2 (en) 2020-02-11
PL3056208T3 (pl) 2021-12-20
CN105611936A (zh) 2016-05-25
EP3056208A1 (en) 2016-08-17
KR20160060072A (ko) 2016-05-27
CN105611936B (zh) 2021-08-20

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