DK3059323T3 - DETECTION OF GENETIC PREDICTION FOR OSTEOARTHRITIS-ASSOCIATED CONDITIONS - Google Patents

DETECTION OF GENETIC PREDICTION FOR OSTEOARTHRITIS-ASSOCIATED CONDITIONS Download PDF

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Publication number
DK3059323T3
DK3059323T3 DK15193948.5T DK15193948T DK3059323T3 DK 3059323 T3 DK3059323 T3 DK 3059323T3 DK 15193948 T DK15193948 T DK 15193948T DK 3059323 T3 DK3059323 T3 DK 3059323T3
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subject
osteoarthritis
allele
genotype
vol
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DK15193948.5T
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Danish (da)
English (en)
Inventor
Jack F Bukowski
Nazneen Aziz
Hwa-Ying Wang
Kenneth Huttner
Steven B Abramson
Mukundan Attur
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Orig3N Inc
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Publication of DK3059323T3 publication Critical patent/DK3059323T3/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK15193948.5T 2008-05-02 2009-05-04 DETECTION OF GENETIC PREDICTION FOR OSTEOARTHRITIS-ASSOCIATED CONDITIONS DK3059323T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4999208P 2008-05-02 2008-05-02
US11874408P 2008-12-01 2008-12-01
EP09740020.4A EP2283156B1 (en) 2008-05-02 2009-05-04 Detecting genetic predisposition to osteoarthritis associated conditions

Publications (1)

Publication Number Publication Date
DK3059323T3 true DK3059323T3 (en) 2019-03-04

Family

ID=41210581

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15193948.5T DK3059323T3 (en) 2008-05-02 2009-05-04 DETECTION OF GENETIC PREDICTION FOR OSTEOARTHRITIS-ASSOCIATED CONDITIONS
DK09740020.4T DK2283156T3 (en) 2008-05-02 2009-05-04 Detection of genetic predisposition to conditions associated with osteoarthritis

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09740020.4T DK2283156T3 (en) 2008-05-02 2009-05-04 Detection of genetic predisposition to conditions associated with osteoarthritis

Country Status (9)

Country Link
US (2) US20100098775A1 (2)
EP (3) EP3059323B1 (2)
JP (3) JP5762282B2 (2)
AU (1) AU2009242490B2 (2)
CA (1) CA2723239C (2)
DK (2) DK3059323T3 (2)
ES (2) ES2561316T3 (2)
NZ (1) NZ589034A (2)
WO (1) WO2009135218A2 (2)

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JP5762282B2 (ja) * 2008-05-02 2015-08-12 インタールーキン ジェネティクス, インコーポレイテッド 変形性関節症に関連する状態に対する遺伝的素因の検出
US20120115137A1 (en) * 2010-08-31 2012-05-10 Kornman Kenneth S Methods of Predicting Osteoarthritis
CN104736723B (zh) * 2012-08-06 2017-10-31 默克专利有限公司 用于预测对fgf‑18化合物的响应性的遗传标记
AU2013301607B2 (en) * 2012-08-06 2018-10-18 Merck Patent Gmbh Prognosis biomarkers in cartilage disorders
WO2017123696A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10337070B2 (en) 2017-01-12 2019-07-02 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
IL273613B2 (en) 2017-09-29 2026-02-01 Merck Patent Gmbh Metabolic biomarkers for predicting response to FGF-18 compound
SI3688468T1 (sl) 2017-09-29 2022-08-31 Merck Patent Gmbh Vnetni biomarkerji za predvidevanje odzivov na spojino FGF-18
IL281333B2 (en) * 2018-09-10 2025-11-01 Merck Patent Gmbh A method for reducing risk in a clinical trial
WO2020112853A1 (en) 2018-11-28 2020-06-04 Genascence Corporation Methods and compositions for treating osteoarthritis
US20220249660A1 (en) 2019-06-06 2022-08-11 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
EP4007819A4 (en) * 2019-08-02 2023-08-09 New York University Methods and compositions for treating arthritis
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

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US4998617A (en) * 1986-09-15 1991-03-12 Laura Lupton Inc Facial cosmetic liquid make up kit
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US5459039A (en) 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
FR2650840B1 (fr) 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
DE69433811T2 (de) 1993-01-07 2005-06-23 Sequenom, Inc., San Diego Dns - sequenzierung durch massenspektronomie
US5593826A (en) * 1993-03-22 1997-01-14 Perkin-Elmer Corporation, Applied Biosystems, Inc. Enzymatic ligation of 3'amino-substituted oligonucleotides
US5686246A (en) * 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
US5942390A (en) 1996-01-12 1999-08-24 Cedars-Sinai Medical Center Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism
US5698399A (en) 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
GB9621129D0 (en) * 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
GB9706359D0 (en) * 1997-03-27 1997-05-14 Gemini International Holdings Polymorphisms of an il-1 receptor antagonist gene
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
WO2003064600A2 (en) * 2002-01-25 2003-08-07 Interleukin Genetics, Inc. The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes
WO2005056837A2 (en) * 2003-11-26 2005-06-23 Applera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
CA2631675A1 (en) * 2005-11-30 2007-06-21 The University Of North Carolina At Chapel Hill Identification of genetic polymorphic variants associated with somatosensory disorders and methods of using the same
JP5762282B2 (ja) * 2008-05-02 2015-08-12 インタールーキン ジェネティクス, インコーポレイテッド 変形性関節症に関連する状態に対する遺伝的素因の検出
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Also Published As

Publication number Publication date
JP6263499B2 (ja) 2018-01-17
EP2283156B1 (en) 2015-11-11
WO2009135218A2 (en) 2009-11-05
JP5762282B2 (ja) 2015-08-12
JP2018038436A (ja) 2018-03-15
JP2011520433A (ja) 2011-07-21
US20100098775A1 (en) 2010-04-22
EP2283156A2 (en) 2011-02-16
ES2561316T3 (es) 2016-02-25
EP3059323B1 (en) 2018-12-12
ES2708826T3 (es) 2019-04-11
EP3059323A1 (en) 2016-08-24
DK2283156T3 (en) 2016-02-15
CA2723239A1 (en) 2009-11-05
JP2015211677A (ja) 2015-11-26
AU2009242490B2 (en) 2015-01-22
US20160340734A1 (en) 2016-11-24
AU2009242490A1 (en) 2009-11-05
CA2723239C (en) 2020-07-21
WO2009135218A3 (en) 2010-04-01
EP3467126A1 (en) 2019-04-10
NZ589034A (en) 2012-10-26

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