DK306890D0 - Udtrykkelse af celleproliferation med decorin - Google Patents

Udtrykkelse af celleproliferation med decorin

Info

Publication number
DK306890D0
DK306890D0 DK306890A DK306890A DK306890D0 DK 306890 D0 DK306890 D0 DK 306890D0 DK 306890 A DK306890 A DK 306890A DK 306890 A DK306890 A DK 306890A DK 306890 D0 DK306890 D0 DK 306890D0
Authority
DK
Denmark
Prior art keywords
decorin
cell proliferation
expression
suppress
proliferation
Prior art date
Application number
DK306890A
Other languages
English (en)
Other versions
DK306890A (da
Inventor
Erkki I Rouslahti
Yu Yamaguchi
Original Assignee
Jolla Cancer Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jolla Cancer Res Found filed Critical Jolla Cancer Res Found
Publication of DK306890A publication Critical patent/DK306890A/da
Publication of DK306890D0 publication Critical patent/DK306890D0/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725—Proteoglycans, e.g. aggreccan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
DK306890A 1988-06-28 1990-12-28 Udtrykkelse af celleproliferation med decorin DK306890D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21270288A 1988-06-28 1988-06-28
PCT/US1989/002770 WO1990000194A1 (en) 1988-06-28 1989-06-23 Suppression of cell proliferation by decorin

Publications (2)

Publication Number Publication Date
DK306890A DK306890A (da) 1990-12-28
DK306890D0 true DK306890D0 (da) 1990-12-28

Family

ID=22792114

Family Applications (1)

Application Number Title Priority Date Filing Date
DK306890A DK306890D0 (da) 1988-06-28 1990-12-28 Udtrykkelse af celleproliferation med decorin

Country Status (11)

Country Link
US (2) US5726149A (da)
EP (1) EP0349480B1 (da)
JP (3) JP2887325B2 (da)
AT (1) ATE120235T1 (da)
AU (1) AU633011B2 (da)
CA (1) CA1340112C (da)
DE (1) DE68921803T2 (da)
DK (1) DK306890D0 (da)
ES (1) ES2070926T3 (da)
FI (1) FI906411A0 (da)
WO (1) WO1990000194A1 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583103A (en) * 1988-06-28 1996-12-10 La Jolla Cancer Research Foundation Inhibition of transforming growth factor beta activity
US5654270A (en) 1988-06-28 1997-08-05 La Jolla Cancer Research Foundation Use of fibromodulin to prevent or reduce dermal scarring
US6509314B1 (en) * 1988-06-28 2003-01-21 The Burnham Institute Methods of preventing or reducing scarring with decorin or biglycan
ES2188585T3 (es) * 1991-11-14 2003-07-01 Jolla Cancer Res Found Inhibidores de factores reguladores celulares y procedimientos para evitar o reducir la formacion de cicatrices.
US5830847A (en) * 1992-10-30 1998-11-03 Hsc Research & Development Limited Partnership Soluble TGF-β-binding endoglin polypeptides and homodimers
US5650389A (en) * 1993-03-01 1997-07-22 University Of Alabama At Birmingham Research Foundation Methods for the inhibition of complement activation
US5453492A (en) * 1993-07-28 1995-09-26 La Jolla Cancer Research Foundation 60 kDa transforming growth factor-β-binding protein and its use to detect or purify TGF-β
ZA946595B (en) * 1993-09-03 1996-02-28 Res Dev Foundation Mutants of the retinoblastoma and P53 genes and uses thereof
US5567807A (en) * 1994-07-08 1996-10-22 La Jolla Cancer Research Foundation Processes for the purification of human recombinant decorin and the detection of guanidinium ions
JP2001520877A (ja) 1997-10-28 2001-11-06 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 血管平滑筋細胞のインビトロ分化、それに関する方法および試薬
HUP0302396A2 (hu) * 2000-05-05 2003-10-28 Gtc Biotherapeutics, Inc. Transzgénikus úton előállított dekorin
KR100989647B1 (ko) 2001-09-24 2010-10-26 오레곤 헬스 앤드 사이언스 유니버시티 식습관의 변화
EP1474163A2 (en) 2002-01-10 2004-11-10 Imperial College Innovations Limited Modification of feeding behavior
AU2003209308A1 (en) * 2002-01-22 2003-09-02 Genzyme Corporation Use of tgf-beta antagonists to treat or to prevent chronic transplant rejection
CN1961003B (zh) 2004-03-31 2013-03-27 健泰科生物技术公司 人源化抗TGF-β抗体
JP5481028B2 (ja) * 2004-10-13 2014-04-23 ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション ウイルス関連リンパ増殖性障害を処置または予防するための方法
KR100747646B1 (ko) * 2005-02-25 2007-08-08 연세대학교 산학협력단 데코린 유전자를 포함하는 유전자 전달 시스템 및 이를 포함하는 약제학적 항종양 조성물
JP2006295872A (ja) * 2005-03-18 2006-10-26 Matsushita Electric Ind Co Ltd 機器固有鍵の生成方法、これを用いた機密情報処理機能を備えた機密情報ｌｓｉ、これを搭載したホスト機器、これに用いられる認証機能付き記録媒体、および認証機能を備えた記録媒体付き携帯端末
BRPI0616463A2 (pt) 2005-09-29 2011-06-21 Merck & Co Inc composto, composição farmacêutica, e, uso de um composto
EP1948675B1 (en) 2005-10-25 2014-07-30 The Johns Hopkins University Methods and compositions for the treatment of marfan syndrome and associated disorders
US8454952B2 (en) 2006-03-13 2013-06-04 The Johns Hopkins University Augmentation of endothelial thromboresistance
JP5489333B2 (ja) 2006-09-22 2014-05-14 メルク・シャープ・アンド・ドーム・コーポレーション 脂肪酸合成阻害剤を用いた治療の方法
DK2083863T3 (da) 2006-10-03 2015-06-22 Genzyme Corp Antistoffer mod tgf-beta til anvendelse til behandling af spædbørn med risiko for udvikling af bronkopulmonal dysplasi
US9053063B2 (en) 2007-02-21 2015-06-09 At&T Intellectual Property I, Lp Method and apparatus for authenticating a communication device
CA2682727C (en) 2007-04-02 2016-03-22 Banyu Pharmaceutical Co., Ltd. Indoledione derivative
ME02464B (me) 2010-03-12 2017-02-20 Genzyme Corp Kombinovana terapija za lečenje raka dojke
CA2823154A1 (en) 2010-12-27 2012-07-05 Lsip, Llc Ips cells and method for generating same
EP3456837A3 (en) * 2011-03-14 2019-04-24 Catalent Pharma Solutions, LLC Decorin compositions and use thereof
US20140308275A1 (en) 2011-07-27 2014-10-16 Inserm (Institut National De La Sante Et De La Recherche Medicale Methods for diagnosing and treating myhre syndrome
WO2013062544A1 (en) 2011-10-26 2013-05-02 Seattle Children's Research Institute Cysteamine in the treatment of fibrotic disease
EP2799537B1 (en) 2011-12-28 2021-09-22 Kyoto Prefectural Public University Corporation Normalization of culture of corneal endothelial cells
JP2016519110A (ja) 2013-04-22 2016-06-30 キャタレント ファーマ ソリューションズ リミテッド ライアビリティ カンパニー 獣医学的デコリン組成物及びそれらの使用
CA2927898C (en) 2013-10-31 2021-11-16 Kyoto Prefectural Public University Corporation Therapeutic drug for diseases related to endoplasmic reticulum cell death in corneal endothelium
US10882903B2 (en) 2015-05-18 2021-01-05 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and compositions for treating an alphavirus infection
AU2020288550A1 (en) * 2019-06-06 2022-01-20 Aroa Biosurgery Limited Bioactive agents and methods related thereto

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU624789B2 (en) * 1987-02-19 1992-06-25 Amgen, Inc. Purified platelet-derived growth factor and methods for purification thereof
US5583103A (en) * 1988-06-28 1996-12-10 La Jolla Cancer Research Foundation Inhibition of transforming growth factor beta activity

Also Published As

Publication number Publication date
ATE120235T1 (de) 1995-04-15
AU633011B2 (en) 1993-01-21
JP2887325B2 (ja) 1999-04-26
JP2003034651A (ja) 2003-02-07
FI906411A7 (fi) 1990-12-27
JPH09117278A (ja) 1997-05-06
US5726149A (en) 1998-03-10
EP0349480B1 (en) 1995-03-22
CA1340112C (en) 1998-11-03
DE68921803T2 (de) 1995-07-13
EP0349480A1 (en) 1990-01-03
ES2070926T3 (es) 1995-06-16
WO1990000194A1 (en) 1990-01-11
FI906411A0 (fi) 1990-12-27
DK306890A (da) 1990-12-28
DE68921803D1 (de) 1995-04-27
JPH03503846A (ja) 1991-08-29
AU3865389A (en) 1990-01-23
US6046162A (en) 2000-04-04

Similar Documents

Publication Publication Date Title
DK306890A (da) Udtrykkelse af celleproliferation med decorin
GR3035603T3 (en) Mammals lacking expression of cd28 transgenic
DE69032406D1 (de) Wundheilmittel enthaltend heparanase
BR9712077A (pt) Expressão de proteìnas de alto nìvel
ES2036192T3 (es) Derivados del acido (met)-acrilico, que contienen grupos uretano, de triciclo (5.2.1.0.2.6) decano.
EP0123811A3 (en) The use of the gal 1 yeast promoter
JPS5771391A (en) Microcarrier cell culture
GR860586B (en) Phenyl- carbamates
PT584788E (pt) Meio livre de soro para celulas de mamiferos
AU3947785A (en) Organosiloxanes
DK432987A (da) Fremgangsmaade til forbedring af ekspressionen af eukaryotprotein
ATE76660T1 (de) Enzyme fuer den abbau von lignin.
DE59010334D1 (de) Wasserstoff/Sauerstoff-Brennstoffzelle
AU545444B2 (en) Cooling of carbon fibre gasification vessel
ZA917561B (en) Media for culture of mammalian cells
DK359487D0 (da) Fremgangsmaade til udvirkning af foroeget ekspression af rekombinant faktor viii i en vaertscelle
EP0362283A4 (en) Bovine interleukin-1_g(a)
AU6654086A (en) Low temperature polymethylsiloxane containing silicon-bonded hydrogen and curable compositions made therewith
ES8601861A1 (es) Un metodo de obtener un isocianato bloqueado
AU586330B2 (en) Process for maximum middle distillate production with minimum hydrogen consumption
GB8503248D0 (en) Culturing cells
NO905610L (no) Undertrykkelse av celleproliferasjon ved hjelp av decorin.
GR3015318T3 (en) Method for culturing cells.
IL80901A0 (en) Growth-promoting cell culture medium and process for the cultivation of cells employing the same
DE59308687D1 (de) Kulturgefäss für Zellkulturen

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment