DK3083683T3 - Sammensætninger og fremgangsmåder til behandling af fedtvævsansamlinger - Google Patents

Sammensætninger og fremgangsmåder til behandling af fedtvævsansamlinger Download PDF

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Publication number
DK3083683T3
DK3083683T3 DK14822035.3T DK14822035T DK3083683T3 DK 3083683 T3 DK3083683 T3 DK 3083683T3 DK 14822035 T DK14822035 T DK 14822035T DK 3083683 T3 DK3083683 T3 DK 3083683T3
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DK
Denmark
Prior art keywords
collections
fatty
procedures
compositions
treatment
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Application number
DK14822035.3T
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English (en)
Inventor
Michael O Boylan
M Michael Wolfe
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Mhs Care Innovation Llc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK14822035.3T 2013-12-17 2014-12-17 Sammensætninger og fremgangsmåder til behandling af fedtvævsansamlinger DK3083683T3 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201361917136P 2013-12-17 2013-12-17
US201461974660P 2014-04-03 2014-04-03
US201462007255P 2014-06-03 2014-06-03
US201462045189P 2014-09-03 2014-09-03
US201462074234P 2014-11-03 2014-11-03
US201462074225P 2014-11-03 2014-11-03
US201462074227P 2014-11-03 2014-11-03
PCT/US2014/070901 WO2015095354A2 (en) 2013-12-17 2014-12-17 Compositions and methods for treating fatty tissue buildup

Publications (1)

Publication Number Publication Date
DK3083683T3 true DK3083683T3 (da) 2021-01-25

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
DK20203790.9T DK3828203T3 (da) 2013-12-17 2014-12-17 Sammensætninger og fremgangsmåder til behandling af fedtvævsopbygning
DK14822035.3T DK3083683T3 (da) 2013-12-17 2014-12-17 Sammensætninger og fremgangsmåder til behandling af fedtvævsansamlinger

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK20203790.9T DK3828203T3 (da) 2013-12-17 2014-12-17 Sammensætninger og fremgangsmåder til behandling af fedtvævsopbygning

Country Status (15)

Country Link
US (3) US9771422B2 (da)
EP (3) EP3828203B1 (da)
JP (3) JP6328769B2 (da)
CN (2) CN113633768B (da)
AU (1) AU2014364768B2 (da)
BR (1) BR112016014042A2 (da)
CA (1) CA2934004C (da)
DK (2) DK3828203T3 (da)
ES (2) ES2846099T3 (da)
HU (1) HUE067414T2 (da)
IL (1) IL246269B (da)
MX (1) MX382215B (da)
PL (2) PL3828203T3 (da)
RU (1) RU2711478C2 (da)
WO (1) WO2015095354A2 (da)

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US11066467B2 (en) 2013-12-17 2021-07-20 Mhs Care-Innovation Llc Compositions and methods for treating ischemic heart disease
US10548951B2 (en) 2013-12-17 2020-02-04 Mhs Care-Innovation Llc Compositions and methods for treating obesity and hyperphagia
ES2846099T3 (es) 2013-12-17 2021-07-28 Mhs Care Innovation Llc Composiciones y métodos para tratar la acumulación de tejidos grasos
CN117106085A (zh) 2015-12-23 2023-11-24 美国安进公司 使用gipr结合蛋白与glp-1激动剂的组合来治疗或改善代谢病症的方法
WO2018102654A1 (en) * 2016-12-01 2018-06-07 Mhs Care-Innovation Llc Compositions and methods for treating obesity and hyperphagia
EP4480537A3 (en) 2017-01-17 2025-03-12 Amgen Inc. Method of treating or ameliorating metabolic disorders using glp-1 receptor agonists conjugated to antagonists for gastric inhibitory peptide receptor (gipr)
CA3062194A1 (en) 2017-06-20 2018-12-27 Amgen Inc. Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
JP7250706B2 (ja) 2017-06-21 2023-04-03 アムジエン・インコーポレーテツド 胃抑制ペプチド受容体(gipr)に対するアンタゴニスト結合タンパク質/glp-1受容体アゴニスト融合タンパク質を使用した代謝障害の治療又は寛解方法
MX2022005595A (es) * 2019-11-07 2022-08-10 Amgen Inc Método para tratar o mejorar el síndrome de cushing usando proteínas de unión para el receptor peptídico inhibidor gástrico (gipr).
WO2021196225A1 (en) * 2020-04-03 2021-10-07 Hjb (Hangzhou) Co., Ltd. Molecular antagonist of gastric inhibitory polypeptide, compositions comprising molecular antagoist of gastric inhibitory polypeptide, and method for treatment of diseases using the same
JP2025524736A (ja) * 2022-06-07 2025-07-31 ヘリコア・バイオファーマ・インコーポレイテッド 体位性頻脈症候群を処置するための組成物及び方法
WO2024209050A1 (en) 2023-04-05 2024-10-10 Antag Therapeutics Aps Gip activity modulators and orthostatic intolerance
WO2025226312A1 (en) * 2024-04-25 2025-10-30 Incregen Therapeutics Llc Fc-null anti-gip antibodies
US20260077054A1 (en) * 2024-09-18 2026-03-19 Helicore Biopharma, Inc. Combinations of anti-gip antibodies and incretins and uses thereof

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ES2846099T3 (es) 2013-12-17 2021-07-28 Mhs Care Innovation Llc Composiciones y métodos para tratar la acumulación de tejidos grasos

Also Published As

Publication number Publication date
IL246269A0 (en) 2016-07-31
CA2934004C (en) 2023-07-04
EP4410833A2 (en) 2024-08-07
DK3828203T3 (da) 2024-07-15
WO2015095354A2 (en) 2015-06-25
CN106068125A (zh) 2016-11-02
EP3083683A2 (en) 2016-10-26
HK1225640A1 (zh) 2017-09-15
AU2014364768A1 (en) 2016-07-07
EP3828203B1 (en) 2024-04-24
AU2014364768B2 (en) 2020-05-28
CN106068125B (zh) 2021-08-31
US20150166657A1 (en) 2015-06-18
JP2019214607A (ja) 2019-12-19
JP6633108B2 (ja) 2020-01-22
US20180030133A1 (en) 2018-02-01
CN113633768A (zh) 2021-11-12
EP4410833A3 (en) 2024-10-23
CN113633768B (zh) 2025-11-11
JP6328769B2 (ja) 2018-05-23
MX2016008102A (es) 2017-05-12
US10196441B2 (en) 2019-02-05
US10538586B2 (en) 2020-01-21
EP3083683B1 (en) 2020-10-28
US9771422B2 (en) 2017-09-26
BR112016014042A2 (pt) 2017-12-05
CA2934004A1 (en) 2015-06-25
JP2017501165A (ja) 2017-01-12
JP2018076376A (ja) 2018-05-17
IL246269B (en) 2021-10-31
ES2984113T3 (es) 2024-10-28
EP3828203A1 (en) 2021-06-02
PL3083683T3 (pl) 2021-08-02
RU2711478C2 (ru) 2020-01-17
WO2015095354A3 (en) 2015-08-13
US20170044254A1 (en) 2017-02-16
HUE067414T2 (hu) 2024-10-28
ES2846099T3 (es) 2021-07-28
PL3828203T3 (pl) 2024-10-21
MX382215B (es) 2025-03-13

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