DK3103453T3 - Medicinsk sammensætning omfattende heterocyklisk diamino-carboxamidforbindelse som aktiv bestanddel - Google Patents

Medicinsk sammensætning omfattende heterocyklisk diamino-carboxamidforbindelse som aktiv bestanddel Download PDF

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Publication number
DK3103453T3
DK3103453T3 DK15746276.3T DK15746276T DK3103453T3 DK 3103453 T3 DK3103453 T3 DK 3103453T3 DK 15746276 T DK15746276 T DK 15746276T DK 3103453 T3 DK3103453 T3 DK 3103453T3
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DK
Denmark
Prior art keywords
active ingredient
medical composition
carboxamide compound
comprehensive heterocyclic
composition comprehensive
Prior art date
Application number
DK15746276.3T
Other languages
English (en)
Inventor
Tomohiro Eguchi
Masamichi Mori
Yoko Yamaki
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Application granted granted Critical
Publication of DK3103453T3 publication Critical patent/DK3103453T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK15746276.3T 2014-02-04 2015-02-03 Medicinsk sammensætning omfattende heterocyklisk diamino-carboxamidforbindelse som aktiv bestanddel DK3103453T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014019226 2014-02-04
PCT/JP2015/053018 WO2015119122A1 (ja) 2014-02-04 2015-02-03 ジアミノヘテロ環カルボキサミド化合物を有効成分とする医薬組成物

Publications (1)

Publication Number Publication Date
DK3103453T3 true DK3103453T3 (da) 2020-04-20

Family

ID=53777926

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15746276.3T DK3103453T3 (da) 2014-02-04 2015-02-03 Medicinsk sammensætning omfattende heterocyklisk diamino-carboxamidforbindelse som aktiv bestanddel

Country Status (30)

Country Link
US (2) US11045468B2 (da)
EP (1) EP3103453B1 (da)
JP (1) JP6390626B2 (da)
KR (1) KR102322338B1 (da)
CN (3) CN116509866A (da)
AU (1) AU2015215578B2 (da)
BR (1) BR112016017897A8 (da)
CA (1) CA2938818C (da)
CY (1) CY1122968T1 (da)
DK (1) DK3103453T3 (da)
EA (1) EA033304B1 (da)
ES (1) ES2788390T3 (da)
HR (1) HRP20200662T1 (da)
HU (1) HUE049437T2 (da)
IL (1) IL247077B (da)
LT (1) LT3103453T (da)
ME (1) ME03775B (da)
MX (1) MX363543B (da)
MY (1) MY193536A (da)
PH (1) PH12016501527B1 (da)
PL (1) PL3103453T3 (da)
PT (1) PT3103453T (da)
RS (1) RS60150B1 (da)
SG (1) SG11201606413RA (da)
SI (1) SI3103453T1 (da)
SM (1) SMT202000214T1 (da)
TW (1) TWI655945B (da)
UA (1) UA120607C2 (da)
WO (1) WO2015119122A1 (da)
ZA (1) ZA201605379B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE049437T2 (hu) * 2014-02-04 2020-09-28 Astellas Pharma Inc Hatóanyagként heterociklusos diamino-karboxamid vegyületet tartalmazó gyógyászati készítmény
SMT202300074T1 (it) * 2015-07-03 2023-05-12 Astellas Pharma Inc Composizione farmaceutica stabile per somministrazione orale
WO2017078049A1 (ja) * 2015-11-04 2017-05-11 アステラス製薬株式会社 ジアミノヘテロ環カルボキサミド化合物を有効成分とするがん免疫治療用、及び／又は、免疫活性化用医薬組成物
CA3129665A1 (en) 2019-03-21 2020-09-24 Onxeo A dbait molecule in combination with kinase inhibitor for the treatment of cancer
KR20220098759A (ko) 2019-11-08 2022-07-12 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) 키나제 억제제에 대해 내성을 획득한 암의 치료 방법
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
CA3231846A1 (en) * 2021-04-08 2022-10-13 Tamara Maes Combinations of lsd1 inhibitors for treating myeloid cancers
WO2022220227A1 (ja) * 2021-04-14 2022-10-20 エーザイ・アール・アンド・ディー・マネジメント株式会社 テトラヒドロピリドピリミジン化合物
WO2023129667A1 (en) 2021-12-30 2023-07-06 Biomea Fusion, Inc. Pyrazine compounds as inhibitors of flt3

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009215168A1 (en) * 2008-02-12 2009-08-20 Dana-Farber Cancer Institute Fish assay for EML4 and ALK fusion in lung cancer
US8815906B2 (en) 2008-03-19 2014-08-26 Chembridge Corporation Tyrosine kinase inhibitors
UY31800A (es) * 2008-05-05 2009-11-10 Smithkline Beckman Corp Metodo de tratamiento de cancer usando un inhibidor de cmet y axl y un inhibidor de erbb
MX2011011875A (es) * 2009-05-08 2011-12-08 Astellas Pharma Inc Compuesto de carboxamida heterociclica diamino.
CN102408411B (zh) * 2011-09-19 2014-10-22 北京康辰药业股份有限公司 一种含喹啉基的羟肟酸类化合物及其制备方法、以及含有该化合物的药物组合物及其应用
JP2014533954A (ja) * 2011-11-21 2014-12-18 イミュノジェン， インコーポレイテッド Ｅｇｆｒ抗体細胞傷害性薬物複合体による、ｅｇｆｒ療法に耐性である腫瘍の治療方法
UA113204C2 (xx) 2012-04-02 2016-12-26 Селективна екстракція хлориду калію з відхідного шенітового розчину з використанням тартратної кислоти як безпечного м'якого екстрагента, придатного до рециркуляції
KR102373193B1 (ko) * 2012-11-21 2022-03-10 얀센 바이오테크 인코포레이티드 이중특이성 EGFR/c-Met 항체
HUE049437T2 (hu) * 2014-02-04 2020-09-28 Astellas Pharma Inc Hatóanyagként heterociklusos diamino-karboxamid vegyületet tartalmazó gyógyászati készítmény
WO2015127234A1 (en) 2014-02-20 2015-08-27 Board Of Regents, The University Of Texas System Use of ibrutinib to treat egfr mutant cancer
SMT202300074T1 (it) * 2015-07-03 2023-05-12 Astellas Pharma Inc Composizione farmaceutica stabile per somministrazione orale

Also Published As

Publication number Publication date
PH12016501527B1 (en) 2019-08-09
UA120607C2 (uk) 2020-01-10
SG11201606413RA (en) 2016-09-29
CN105939714A (zh) 2016-09-14
AU2015215578B2 (en) 2019-07-11
HUE049437T2 (hu) 2020-09-28
CA2938818C (en) 2023-03-07
LT3103453T (lt) 2020-05-11
CN116509866A (zh) 2023-08-01
NZ722750A (en) 2020-11-27
MX363543B (es) 2019-03-27
CY1122968T1 (el) 2021-10-29
TWI655945B (zh) 2019-04-11
PT3103453T (pt) 2020-05-06
RS60150B1 (sr) 2020-05-29
MX2016010134A (es) 2016-10-07
PL3103453T3 (pl) 2020-06-29
US20210290618A1 (en) 2021-09-23
EA033304B1 (ru) 2019-09-30
MY193536A (en) 2022-10-18
US11045468B2 (en) 2021-06-29
AU2015215578A1 (en) 2016-08-18
PH12016501527A1 (en) 2017-02-06
EP3103453B1 (en) 2020-04-01
KR20160110498A (ko) 2016-09-21
HRP20200662T1 (hr) 2020-10-02
ZA201605379B (en) 2018-05-30
KR102322338B1 (ko) 2021-11-05
US20160339020A1 (en) 2016-11-24
EP3103453A1 (en) 2016-12-14
SI3103453T1 (sl) 2020-10-30
IL247077B (en) 2020-08-31
CN113425727A (zh) 2021-09-24
TW201613594A (en) 2016-04-16
SMT202000214T1 (it) 2020-05-08
CA2938818A1 (en) 2015-08-13
US11925638B2 (en) 2024-03-12
WO2015119122A1 (ja) 2015-08-13
ES2788390T3 (es) 2020-10-21
EA201691570A1 (ru) 2016-11-30
JP6390626B2 (ja) 2018-09-19
AU2015215578A2 (en) 2016-10-20
BR112016017897A8 (pt) 2020-06-30
ME03775B (me) 2021-04-20
IL247077A0 (en) 2016-09-29
EP3103453A4 (en) 2017-09-06
JPWO2015119122A1 (ja) 2017-03-23

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