DK3165607T3 - Biologisk aktive oligonukleotider, der kan modulere immunsystemet - Google Patents
Biologisk aktive oligonukleotider, der kan modulere immunsystemet Download PDFInfo
- Publication number
- DK3165607T3 DK3165607T3 DK16202636.3T DK16202636T DK3165607T3 DK 3165607 T3 DK3165607 T3 DK 3165607T3 DK 16202636 T DK16202636 T DK 16202636T DK 3165607 T3 DK3165607 T3 DK 3165607T3
- Authority
- DK
- Denmark
- Prior art keywords
- modulate
- biologically active
- immune system
- active oligonucleotides
- oligonucleotides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6866—Interferon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/313—Phosphorodithioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
- C12N2320/11—Applications; Uses in screening processes for the determination of target sites, i.e. of active nucleic acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10196273A EP2468866A1 (en) | 2010-12-21 | 2010-12-21 | Biologically active oligonucleotides capable of modulating the immune system |
| EP10196290A EP2468867A1 (en) | 2010-12-21 | 2010-12-21 | Methods for identifying biologically active oligonucleotides capable of modulating the immune system |
| EP10196285 | 2010-12-21 | ||
| EP11802929.7A EP2655622B1 (en) | 2010-12-21 | 2011-12-20 | Methods for identifying biologically active oligonucleotides capable of modulating the immune system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3165607T3 true DK3165607T3 (da) | 2021-05-31 |
Family
ID=45440530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16202636.3T DK3165607T3 (da) | 2010-12-21 | 2011-12-20 | Biologisk aktive oligonukleotider, der kan modulere immunsystemet |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9157919B2 (da) |
| EP (2) | EP2655622B1 (da) |
| CA (1) | CA2859698C (da) |
| DK (1) | DK3165607T3 (da) |
| ES (1) | ES2870458T3 (da) |
| WO (1) | WO2012084996A2 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3043768A1 (en) | 2016-11-29 | 2018-06-07 | PureTech Health LLC | Exosomes for delivery of therapeutic agents |
| WO2018231752A1 (en) * | 2017-06-12 | 2018-12-20 | University Of Miami | Sting-dependent activators for treatment of disease |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040224405A1 (en) * | 2003-05-06 | 2004-11-11 | Dharmacon Inc. | siRNA induced systemic gene silencing in mammalian systems |
| CN1989439B (zh) * | 2004-05-06 | 2010-12-29 | 美国政府健康及人类服务部 | 治疗葡萄膜炎的方法以及组合物 |
| CN1865275B (zh) * | 2005-05-17 | 2011-06-15 | 长春华普生物技术有限公司 | 对人b细胞肿瘤有治疗作用的人工合成的单链脱氧核苷酸 |
| ES2581480T3 (es) * | 2007-05-04 | 2016-09-06 | Index Pharmaceuticals Ab | Compuestos inhibidores de crecimiento tumoral y métodos de uso de los mismos |
| JP5547637B2 (ja) * | 2007-10-05 | 2014-07-16 | インデックス・ファーマシューティカルズ・アクチエボラーグ | 浮腫を治療または軽減するための新規な化合物およびその使用方法 |
| US20110280934A1 (en) * | 2008-11-04 | 2011-11-17 | Asa Karlsson | Increased Expression of Specific Antigens |
| JP5749651B2 (ja) * | 2008-11-04 | 2015-07-15 | インデックス・ファーマシューティカルズ・アクチエボラーグ | 多形核細胞の動員および/または遊走を減少させる化合物および方法 |
-
2011
- 2011-12-20 US US13/995,304 patent/US9157919B2/en active Active
- 2011-12-20 WO PCT/EP2011/073468 patent/WO2012084996A2/en not_active Ceased
- 2011-12-20 EP EP11802929.7A patent/EP2655622B1/en active Active
- 2011-12-20 ES ES16202636T patent/ES2870458T3/es active Active
- 2011-12-20 DK DK16202636.3T patent/DK3165607T3/da active
- 2011-12-20 EP EP16202636.3A patent/EP3165607B1/en active Active
- 2011-12-20 CA CA2859698A patent/CA2859698C/en active Active
-
2015
- 2015-08-31 US US14/840,628 patent/US9593337B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2655622B1 (en) | 2017-01-11 |
| WO2012084996A3 (en) | 2012-08-16 |
| EP3165607B1 (en) | 2021-04-07 |
| CA2859698A1 (en) | 2012-06-28 |
| US9593337B2 (en) | 2017-03-14 |
| EP3165607A3 (en) | 2017-07-26 |
| WO2012084996A2 (en) | 2012-06-28 |
| US20160024508A1 (en) | 2016-01-28 |
| EP3165607A2 (en) | 2017-05-10 |
| EP2655622A2 (en) | 2013-10-30 |
| US20130281519A1 (en) | 2013-10-24 |
| CA2859698C (en) | 2021-03-02 |
| ES2870458T3 (es) | 2021-10-27 |
| US9157919B2 (en) | 2015-10-13 |
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