DK3169703T3 - Kimær antigenreceptor og anvendelse deraf - Google Patents

Kimær antigenreceptor og anvendelse deraf Download PDF

Info

Publication number: DK3169703T3
Authority: DK; Denmark
Prior art keywords: chimary; antigen receptor; antigen; receptor; chimary antigen
Prior art date: 2014-07-16

Application number

DK15738356.3T

Other languages

English (en)

Other versions

DK3169703T4 (da

Inventor

Hinrich Abken

Andreas Hombach

Original Assignee

Hinrich Abken

Andreas Hombach

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-07-16

Filing date

2015-07-16

Publication date

2020-11-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51178778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3169703(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2015-07-16 Application filed by Hinrich Abken, Andreas Hombach filed Critical Hinrich Abken

2020-11-16 Application granted granted Critical

2020-11-16 Publication of DK3169703T3 publication Critical patent/DK3169703T3/da

2024-02-26 Publication of DK3169703T4 publication Critical patent/DK3169703T4/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

DK15738356.3T 2014-07-16 2015-07-16 Kimær antigenreceptor og anvendelse deraf DK3169703T4 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP14177278		2014-07-16
PCT/EP2015/066252 WO2016008973A1 (en)	2014-07-16	2015-07-16	Chimeric antigen receptor and its use

Publications (2)

Publication Number	Publication Date
DK3169703T3 true DK3169703T3 (da)	2020-11-16
DK3169703T4 DK3169703T4 (da)	2024-02-26

Family

ID=51178778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK15738356.3T DK3169703T4 (da)	2014-07-16	2015-07-16	Kimær antigenreceptor og anvendelse deraf

Country Status (6)

Country	Link
US (2)	US10865243B2 (da)
EP (1)	EP3169703B2 (da)
DK (1)	DK3169703T4 (da)
ES (1)	ES2833162T5 (da)
FI (1)	FI3169703T4 (da)
WO (1)	WO2016008973A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN105940102B (zh)	2013-08-26	2020-02-18	海瑞克·亚柏坎	抗cd30嵌合抗原受体及其用途
CA2976089C (en) *	2015-02-10	2026-01-13	Minerva Biotechnologies Corporation	Humanized anti-muc1* antibodies
EP3098237B1 (en) *	2015-05-28	2018-08-01	Universität Zu Köln	Anti-toso chimeric antigen receptor and its use
CN109705211B (zh) *	2017-10-26	2020-08-18	苏州复融生物技术有限公司	一种IgG1 Fc单体及其应用
GB201721833D0 (en) *	2017-12-22	2018-02-07	Cancer Research Tech Ltd	Fusion proteins
US12491153B2 (en)	2018-01-03	2025-12-09	Qu Biologics Inc.	Innate targeting of adoptive cellular therapies
US12005080B2 (en) *	2018-03-26	2024-06-11	Oricell Therapeutics Co., Ltd.	Method for promoting proliferation of immune cells
WO2019240934A1 (en) *	2018-06-12	2019-12-19	Promab Biotechnologies, Inc.	Plap-car-effector cells
WO2020135426A1 (zh) *	2018-12-24	2020-07-02	信达生物制药(苏州)有限公司	全人源的抗cd30单链抗体及其应用
EP3902838A4 (en)	2018-12-26	2022-12-21	Nanjing Legend Biotech Co., Ltd.	Cd30-binding moieties, chimeric antigen receptors, and uses thereof
EP3747904A1 (en) *	2019-06-03	2020-12-09	Universität Regensburg	Cd25-specific chimeric antigen receptors and their uses
WO2021221927A1 (en)	2020-04-27	2021-11-04	Parsons Corporation	Narrowband iq signal obfuscation
TW202210084A (zh)	2020-06-05	2022-03-16	新加坡商泰莎治療有限公司	Cd30陽性癌症之治療
AR124414A1 (es)	2020-12-18	2023-03-22	Century Therapeutics Inc	Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
US12036644B2 (en)	2021-02-08	2024-07-16	Apex Brands, Inc.	Bolt extractor with distal end engagement areas
CN117529551A (zh)	2021-04-27	2024-02-06	贝勒医学院	表达嵌合抗原受体的病毒特异性免疫细胞
EP4355340A4 (en)	2021-06-16	2025-05-21	Instil Bio, Inc.	RECEPTORS FOR TARGETED COSTIMULATION FOR ADOPTIVE CELL THERAPY
TW202321443A (zh)	2021-10-26	2023-06-01	新加坡商泰莎治療有限公司	用於生產編碼car之反轉錄病毒載體的細胞株
WO2023104910A1 (en)	2021-12-08	2023-06-15	Tessa Therapeutics Ltd.	Treatment of lymphoma
KR20250024750A (ko)	2022-04-13	2025-02-19	티크바 알로셀 피티이. 엘티디.	치료용 t 세포 산물
CN121039155A (zh) *	2023-02-09	2025-11-28	星尘生物科技(上海)有限公司	一种嵌合抗原受体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2822366A1 (en) *	2010-12-23	2012-06-28	Janssen Biotech, Inc.	Active protease-resistant antibody fc mutants
JP6850528B2 (ja)	2012-02-13	2021-03-31	シアトルチルドレンズホスピタルドゥーイングビジネスアズシアトルチルドレンズリサーチインスティテュート	二重特異性キメラ抗原受容体およびその治療的使用
US20130280220A1 (en) *	2012-04-20	2013-10-24	Nabil Ahmed	Chimeric antigen receptor for bispecific activation and targeting of t lymphocytes
CN105940102B (zh) *	2013-08-26	2020-02-18	海瑞克·亚柏坎	抗cd30嵌合抗原受体及其用途

2015
- 2015-07-16 EP EP15738356.3A patent/EP3169703B2/en active Active
- 2015-07-16 US US15/325,638 patent/US10865243B2/en active Active
- 2015-07-16 FI FIEP15738356.3T patent/FI3169703T4/fi active
- 2015-07-16 ES ES15738356T patent/ES2833162T5/es active Active
- 2015-07-16 DK DK15738356.3T patent/DK3169703T4/da active
- 2015-07-16 WO PCT/EP2015/066252 patent/WO2016008973A1/en not_active Ceased
2020
- 2020-11-12 US US17/096,192 patent/US12410248B2/en active Active

Also Published As

Publication number	Publication date
EP3169703A1 (en)	2017-05-24
US12410248B2 (en)	2025-09-09
FI3169703T4 (fi)	2024-03-01
US20220002401A1 (en)	2022-01-06
DK3169703T4 (da)	2024-02-26
ES2833162T3 (es)	2021-06-14
EP3169703B2 (en)	2023-12-13
WO2016008973A1 (en)	2016-01-21
US10865243B2 (en)	2020-12-15
US20170145095A1 (en)	2017-05-25
EP3169703B1 (en)	2020-09-02
ES2833162T5 (es)	2024-06-12

Publication	Publication Date	Title
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