DK3177741T3 - Genetisk modifikation af (s)-mælkesyreproducerende termofile bakterier - Google Patents

Genetisk modifikation af (s)-mælkesyreproducerende termofile bakterier Download PDF

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Publication number
DK3177741T3
DK3177741T3 DK15738320.9T DK15738320T DK3177741T3 DK 3177741 T3 DK3177741 T3 DK 3177741T3 DK 15738320 T DK15738320 T DK 15738320T DK 3177741 T3 DK3177741 T3 DK 3177741T3
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Denmark
Prior art keywords
lactic acid
genetic modification
thermophilic bacteria
producing thermophilic
producing
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DK15738320.9T
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English (en)
Inventor
Kranenburg Richard Van
Anna Verhoef
Marinus Petrus Machielsen
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Purac Biochem Bv
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Publication of DK3177741T3 publication Critical patent/DK3177741T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56Lactic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008Phosphate acetyltransferase (2.3.1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01054Formate C-acetyltransferase (2.3.1.54), i.e. pyruvate formate-lyase or PFL
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/03Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03003Methylglyoxal synthase (4.2.3.3)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK15738320.9T 2014-07-23 2015-07-13 Genetisk modifikation af (s)-mælkesyreproducerende termofile bakterier DK3177741T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14178150.0A EP2977471A1 (en) 2014-07-23 2014-07-23 Genetic modification of (S)-lactic acid producing thermophilic bacteria
PCT/EP2015/065995 WO2016012298A1 (en) 2014-07-23 2015-07-13 Genetic modification of (s)-lactic acid producing thermophilic bacteria

Publications (1)

Publication Number Publication Date
DK3177741T3 true DK3177741T3 (da) 2022-09-12

Family

ID=51211698

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15738320.9T DK3177741T3 (da) 2014-07-23 2015-07-13 Genetisk modifikation af (s)-mælkesyreproducerende termofile bakterier

Country Status (15)

Country Link
US (1) US10273509B2 (da)
EP (2) EP2977471A1 (da)
JP (2) JP6549214B2 (da)
KR (1) KR101999975B1 (da)
CN (1) CN106536543B (da)
AU (1) AU2015294138B2 (da)
BR (1) BR112017000940B1 (da)
CA (1) CA2955720C (da)
DK (1) DK3177741T3 (da)
ES (1) ES2924250T3 (da)
HU (1) HUE059443T2 (da)
PL (1) PL3177741T3 (da)
RU (1) RU2671528C2 (da)
UA (1) UA121479C2 (da)
WO (1) WO2016012298A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021020703A2 (pt) 2019-04-18 2021-12-14 BluCon Biotech GmbH Bactérias termofílicas extremas do gênero caldicellulosiruptor adequadas para a conversão de biomassa celulósica e de amido
WO2024126054A1 (en) 2022-12-15 2024-06-20 Feedstocksunited B.V. Trioxane as unifying fermentation feedstock

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1013682C2 (nl) 1999-11-26 2001-05-30 Purac Biochem Bv Werkwijze en inrichting voor het zuiveren van een waterige oplossing van melkzuur.
GB0000185D0 (en) 2000-01-06 2000-03-01 Agrol Limited Ethanol production
JP4336082B2 (ja) 2001-05-29 2009-09-30 花王株式会社 宿主微生物
US7585674B2 (en) 2001-05-29 2009-09-08 Kao Corporation Host microorganisms
GB0117551D0 (en) 2001-07-18 2001-09-12 Elsworth Biotech Ltd Lastic acid production
CN100560727C (zh) * 2003-09-30 2009-11-18 三井化学株式会社 用于生产d-乳酸的生物催化剂
US7098009B2 (en) * 2004-03-04 2006-08-29 University Of Florida Research Foundation, Inc. Production of chemicals from lignocellulose, biomass or sugars
CA2607052A1 (en) 2005-05-04 2006-11-09 Tmo Renewables Limited Thermophilic microorganisms with inactivated lactate dehydrogenase gene (ldh) for ethanol production
DK2305826T3 (da) * 2005-08-10 2016-06-27 Univ Florida Materialer og fremgangsmåder til effektiv mælkesyreproduktion
ES2290926T3 (es) 2006-01-24 2008-02-16 Lurgi Zimmer Gmbh Procedimiento para la esterificacion de acido tereftalico con butanodiol, procedimiento para la preparacion de poli(tereftalato de butileno)y dispositivo para ello.
US8932841B2 (en) 2006-09-28 2015-01-13 Tmo Renewables Limited Thermophilic microorganisms for ethanol production
RU2355759C1 (ru) 2007-08-14 2009-05-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ АРОМАТИЧЕСКОЙ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ГЕН ydiB, СПОСОБ ПОЛУЧЕНИЯ СЛОЖНОГО ЭФИРА НИЗШИХ АЛКИЛОВ АЛЬФА-L-АСПАРТИЛ-L-ФЕНИЛАЛАНИНА
GB0820262D0 (en) 2008-11-05 2008-12-10 Tmo Renewables Ltd Microorganisms
DK2446019T3 (da) 2009-06-23 2015-06-15 Bp Corp North America Inc Rekombinant ethanologen bakterie
WO2011021629A1 (ja) * 2009-08-21 2011-02-24 旭硝子株式会社 形質転換体およびその製造方法、ならびに乳酸の製造方法

Also Published As

Publication number Publication date
AU2015294138A1 (en) 2017-02-09
CN106536543B (zh) 2021-05-07
UA121479C2 (uk) 2020-06-10
EP2977471A1 (en) 2016-01-27
WO2016012298A1 (en) 2016-01-28
ES2924250T3 (es) 2022-10-05
JP2019088328A (ja) 2019-06-13
RU2671528C2 (ru) 2018-11-01
JP2017521081A (ja) 2017-08-03
RU2017102895A3 (da) 2018-08-27
HUE059443T2 (hu) 2022-11-28
EP3177741A1 (en) 2017-06-14
US20170298398A1 (en) 2017-10-19
BR112017000940A2 (pt) 2017-11-14
CA2955720A1 (en) 2016-01-28
BR112017000940B1 (pt) 2024-01-16
EP3177741B1 (en) 2022-06-29
JP6549214B2 (ja) 2019-07-24
PL3177741T3 (pl) 2022-10-03
RU2017102895A (ru) 2018-08-27
CA2955720C (en) 2019-11-05
CN106536543A (zh) 2017-03-22
KR20170028445A (ko) 2017-03-13
US10273509B2 (en) 2019-04-30
AU2015294138B2 (en) 2018-07-19
KR101999975B1 (ko) 2019-07-15

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