DK3188759T3 - Fremgangsmåde til behandling og sammensætninger, der omfatter en dobbelt pi3k-delta-gamma-kinaseinhibitor og et kortikosteroid - Google Patents

Fremgangsmåde til behandling og sammensætninger, der omfatter en dobbelt pi3k-delta-gamma-kinaseinhibitor og et kortikosteroid Download PDF

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Publication number
DK3188759T3
DK3188759T3 DK15774713.0T DK15774713T DK3188759T3 DK 3188759 T3 DK3188759 T3 DK 3188759T3 DK 15774713 T DK15774713 T DK 15774713T DK 3188759 T3 DK3188759 T3 DK 3188759T3
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costeroid
cortic
delta
treatment
compositions containing
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DK15774713.0T
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English (en)
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Venkata Satya Vakkalanka Swaroop Kumar
Srikant Viswanadha
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Rhizen Pharmaceuticals S A
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Immunology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
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  • Cardiology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
DK15774713.0T 2014-09-03 2015-09-03 Fremgangsmåde til behandling og sammensætninger, der omfatter en dobbelt pi3k-delta-gamma-kinaseinhibitor og et kortikosteroid DK3188759T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN4287CH2014 2014-09-03
PCT/IB2015/056720 WO2016035032A1 (en) 2014-09-03 2015-09-03 Method of treatment and compositions comprising a dual pi3k delta-gamma kinase inhibitor and a corticosteroid

Publications (1)

Publication Number Publication Date
DK3188759T3 true DK3188759T3 (da) 2020-06-29

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DK15774713.0T DK3188759T3 (da) 2014-09-03 2015-09-03 Fremgangsmåde til behandling og sammensætninger, der omfatter en dobbelt pi3k-delta-gamma-kinaseinhibitor og et kortikosteroid

Country Status (26)

Country Link
US (2) US10786504B2 (da)
EP (2) EP3701950A1 (da)
JP (3) JP6559775B2 (da)
KR (1) KR20170044203A (da)
CN (2) CN113332439A (da)
AU (2) AU2015310545B2 (da)
BR (1) BR112017004163A2 (da)
CA (1) CA2958988A1 (da)
CL (1) CL2017000512A1 (da)
CY (1) CY1123075T1 (da)
DK (1) DK3188759T3 (da)
EA (2) EA038527B1 (da)
ES (1) ES2802202T3 (da)
HR (1) HRP20200968T1 (da)
HU (1) HUE049480T2 (da)
IL (2) IL250918B (da)
LT (1) LT3188759T (da)
MX (2) MX376875B (da)
PH (1) PH12017500378A1 (da)
PL (1) PL3188759T3 (da)
PT (1) PT3188759T (da)
RS (1) RS60450B1 (da)
SG (2) SG10202100596SA (da)
SI (1) SI3188759T1 (da)
SM (1) SMT202000345T1 (da)
WO (1) WO2016035032A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113557020A (zh) * 2018-09-14 2021-10-26 瑞真药业公司 包含crac抑制剂和皮质类固醇的组合物及其使用方法
CN114206332B (zh) 2019-06-04 2024-08-23 艾库斯生物科学有限公司 2,3,5-三取代吡唑并[1,5-a]嘧啶化合物
CN116492351B (zh) * 2023-03-13 2024-03-12 香港大学深圳医院 氯替泼诺在制备治疗早发性卵巢功能不全及卵巢响应匮乏药物中的应用

Family Cites Families (17)

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US4018774A (en) 1976-02-13 1977-04-19 E. R. Squibb & Sons, Inc. Steroidal [16α,17-d]isoxazolidines
SE8106165L (sv) 1981-10-19 1983-04-20 Atlas Copco Ab Forfarande for bergbultning och bergbult
GB0415747D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
CA2711558C (en) 2008-01-04 2016-12-13 Intellikine, Inc. Phosphatidyl inositol-3 kinase inhibiting compounds
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
US11058699B2 (en) 2008-07-01 2021-07-13 Wisconsin Alumni Research Foundation Method and compositions for inhibition of double stranded DNA viruses
CN102481282A (zh) * 2009-03-24 2012-05-30 新加坡国立大学 青蒿素衍生物用于治疗哮喘和慢性阻塞性肺病(copd)的用途
EP2993178A1 (en) 2009-09-11 2016-03-09 CHIESI FARMACEUTICI S.p.A. Glucocorticoid condensed in position 16,17 with an isoxazolidine group
SG10201500895XA (en) 2009-11-05 2015-04-29 Rhizen Pharmaceuticals Sa Chromen-4-one Derivatives As Kinase Modulators
EP2528607A4 (en) * 2010-01-28 2014-07-16 Univ Johns Hopkins COMPOSITIONS AND METHODS FOR REVERSING A CORTICOSTEROID RESISTANCE OR TREATING RESPIRATORY RESPONSE
EP3689364A1 (en) * 2010-02-08 2020-08-05 Shenzhen Evergreen Therapeutics Co., Ltd. Methods for the use of progestogen as a glucocorticoid sensitizer
AU2012205669B2 (en) 2011-01-10 2015-08-20 Infinity Pharmaceuticals Inc. Processes for preparing isoquinolinones and solid forms of isoquinolinones
UA113508C2 (xx) 2011-03-15 2017-02-10 Ізоксазолідинові похідні
RS58326B1 (sr) 2011-05-04 2019-03-29 Rhizen Pharmaceuticals S A Nova jedinjenja kao modulatori proteinskih kinaza
CA2872252C (en) 2012-05-22 2019-06-18 Atlas Copco Canada Inc. Rock bolt and method of installing a rock bolt
WO2014072937A1 (en) * 2012-11-08 2014-05-15 Rhizen Pharmaceuticals Sa Pharmaceutical compositions containing a pde4 inhibitor and a pi3 delta or dual pi3 delta-gamma kinase inhibitor
CN204282361U (zh) 2014-12-11 2015-04-22 湖南科技大学 一种带钢丝网的软土地基充气锚杆

Also Published As

Publication number Publication date
CL2017000512A1 (es) 2017-11-03
HUE049480T2 (hu) 2020-09-28
HRP20200968T1 (hr) 2020-10-16
SG11201701499YA (en) 2017-03-30
US10786504B2 (en) 2020-09-29
KR20170044203A (ko) 2017-04-24
JP2021191804A (ja) 2021-12-16
SI3188759T1 (sl) 2020-08-31
JP2019172708A (ja) 2019-10-10
US20170281630A1 (en) 2017-10-05
CN113332439A (zh) 2021-09-03
EP3188759A1 (en) 2017-07-12
LT3188759T (lt) 2020-07-10
EA202092492A1 (ru) 2021-07-30
EP3188759B1 (en) 2020-04-01
AU2015310545B2 (en) 2020-10-22
PT3188759T (pt) 2020-07-02
EA038527B1 (ru) 2021-09-10
MX2017002878A (es) 2017-05-30
MX376875B (es) 2025-03-07
RS60450B1 (sr) 2020-07-31
NZ729419A (en) 2021-08-27
AU2021200051A1 (en) 2021-02-18
JP6559775B2 (ja) 2019-08-14
EP3701950A1 (en) 2020-09-02
IL250918B (en) 2021-02-28
MX2020011472A (es) 2020-12-07
AU2015310545A1 (en) 2017-03-16
CA2958988A1 (en) 2016-03-10
EA201790379A1 (ru) 2017-06-30
CN106714842B (zh) 2021-07-02
IL250918A0 (en) 2017-04-30
PH12017500378A1 (en) 2017-07-17
WO2016035032A1 (en) 2016-03-10
CY1123075T1 (el) 2021-10-29
JP2017525739A (ja) 2017-09-07
ES2802202T3 (es) 2021-01-15
SMT202000345T1 (it) 2020-07-08
PL3188759T3 (pl) 2020-11-02
US20210030757A1 (en) 2021-02-04
SG10202100596SA (en) 2021-02-25
CN106714842A (zh) 2017-05-24
IL280686A (en) 2021-03-25
BR112017004163A2 (pt) 2017-12-05

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